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  1. Book ; Online: Kontrollräume und Raumkontrolle

    Schröder, David Joshua

    Infrastrukturelle Kontrollzentralen in Zeiten der Digitalisierung

    (Re-Figuration von Räumen)

    2022  

    Series title Re-Figuration von Räumen
    Keywords Sociology ; Human geography ; Architecture ; Raum ; Digitalisierung ; Infrastruktur ; Smart City ; Moderne ; Refiguration ; Steuerung ; Kontrolle ; Arbeit ; Architektur ; Soziologie ; Space ; Digitalization ; Infrastructure ; Modernity ; Control System ; Control ; Work
    Language 0|d
    Size 1 electronic resource (304 pages)
    Publisher transcript Verlag
    Publishing place Bielefeld
    Document type Book ; Online
    Note German ; Open Access
    HBZ-ID HT021618591
    ISBN 9783837662337 ; 3837662330
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Prototype Description and Ex Vivo Evaluation of a System for Combined Endorectal Magnetic Resonance Imaging and In-Bore Biopsy of the Prostate.

    Coakley, Fergus V / Foster, Bryan R / Schroeder, David W / Rooney, William D / Jones, Randall W / Amling, Christopher L

    Journal of computer assisted tomography

    2024  

    Abstract: Abstract: We describe early ex vivo proof-of-concept testing of a novel system composed of a disposable endorectal coil and converging multichannel needle guide with a reusable clamp stand, embedded electronics, and baseplate to allow for endorectal ... ...

    Abstract Abstract: We describe early ex vivo proof-of-concept testing of a novel system composed of a disposable endorectal coil and converging multichannel needle guide with a reusable clamp stand, embedded electronics, and baseplate to allow for endorectal magnetic resonance (MR) imaging and in-bore MRI-targeted biopsy of the prostate as a single integrated procedure. Using prostate phantoms imaged with standard T2-weighted sequences in a Siemens 3T Prisma MR scanner, we measured the signal-to-noise ratio in successive 1-cm distances from the novel coil and from a commercially available inflatable balloon coil and measured the lateral and longitudinal deviation of the tip of a deployed MR compatible needle from the intended target point. Signal-to-noise ratio obtained with the novel system was significantly better than the inflatable balloon coil at each of five 1-cm intervals, with a mean improvement of 78% (P < 0.05). In a representative sampling of 15 guidance channels, the mean lateral deviation for MR imaging-guided needle positioning was 1.7 mm and the mean longitudinal deviation was 2.0 mm. Our ex vivo results suggest that our novel system provides significantly improved signal-to-noise ratio when compared with an inflatable balloon coil and is capable of accurate MRI-guided needle deployment.
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80392-3
    ISSN 1532-3145 ; 0363-8715
    ISSN (online) 1532-3145
    ISSN 0363-8715
    DOI 10.1097/RCT.0000000000001583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1388: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Development of the national bariatric prioritization tool in Aotearoa New Zealand.

    Srikumar, Gajan / Schroeder, David / McEwan, Christopher / MacCormick, Andrew D

    ANZ journal of surgery

    2023  Volume 93, Issue 12, Page(s) 2843–2850

    Abstract: Background: Bariatric surgery is a proven effective method of reducing obesity and reversing or preventing obesity-related comorbidities. The aim of this study is to describe the development of a tool to assist with the prioritization of patients with ... ...

    Abstract Background: Bariatric surgery is a proven effective method of reducing obesity and reversing or preventing obesity-related comorbidities. The aim of this study is to describe the development of a tool to assist with the prioritization of patients with obesity for bariatric surgery. The tool would meet the criteria for being evidence-based, fair, implementable and transparent.
    Methods: The development of the tool involved a validated step-by-step process based on the consensus of clinical judgement of the New Zealand Ministry of Health working party. The process involved elicitation of criteria, clinical ranking of vignettes and creation of weightings using the 1000Minds® tool. The concurrent validity was tested by comparing tool rankings of vignettes to clinical judgement rankings.
    Results: Four major criteria (impact on life, likelihood of achieving maximum benefit with respect to control of diabetes, duration of benefit and surgical risk) are used to characterize the need and potential to benefit. The impact on life criterion has the largest weighting (up to 44.3%). There was good concurrent validity with a correlation coefficient r = 0.67.
    Conclusion: The tool as presented is evidence-based, transparent and internally valid. The next step is to assess the predictive validity of the tool using real patient data to evaluate the effectiveness of the tool and determine what modifications may be required.
    MeSH term(s) Humans ; New Zealand/epidemiology ; Obesity/surgery ; Bariatric Surgery ; Diabetes Mellitus
    Language English
    Publishing date 2023-07-23
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.18623
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 180: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Reviews.

    Dean Schroeder, David J

    Aerospace medicine and human performance

    2015  Volume 86, Issue 8, Page(s) 752–753

    Language English
    Publishing date 2015-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2809085-8
    ISSN 2375-6322 ; 2375-6314
    ISSN (online) 2375-6322
    ISSN 2375-6314
    DOI 10.3357/AMHP.4205.2015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 57: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Online: The first 250 years of the Heinrich 11 iceberg discharge

    Guarino, Maria Vittoria / Sime, Louise / Schroeder, David / Ridley, Jeff

    eISSN: 1814-9332

    Last Interglacial HadGEM3-GC3.1 simulations for CMIP6-PMIP4

    2022  

    Abstract: The Heinrich 11 event is simulated using the HadGEM3 model during the Last Interglacial period. We apply 0.2 Sv of meltwater forcing across the North Atlantic during a 250 years long simulation. We find that the strength of the Atlantic Meridional ... ...

    Abstract The Heinrich 11 event is simulated using the HadGEM3 model during the Last Interglacial period. We apply 0.2 Sv of meltwater forcing across the North Atlantic during a 250 years long simulation. We find that the strength of the Atlantic Meridional Overturning Circulation is reduced by 60 % after 150 years of meltwater forcing, with an associated decrease of 0.2 to 0.4 PW in meridional ocean heat transport at all latitudes. The changes in ocean heat transport affect surface temperatures. The largest increase in the meridional surface temperature gradient occurs between 40–50 N. This increase is associated with a strengthening of 20 % in 850 hPa winds. The stream jet intensification in the Northern Hemisphere in return alters the temperature structure of the ocean heat through an increased gyre circulation, and associated heat transport (+0.1–0.2 PW), at the mid-latitudes, and a decreased gyre ocean heat transport (−0.2 PW) at high-latitudes. The changes in meridional temperature and pressure gradients cause the Intertropical Convergence Zone (ITCZ) to move southward, leading to stronger westerlies and a more positive Southern Annual Mode (SAM) in the Southern Hemisphere. The positive SAM influences sea ice formation leading to an increase in Antarctic sea ice. Our coupled-model simulation framework shows that the classical "thermal bipolar see-saw' has previously undiscovered consequences in both Hemispheres: these include Northern Hemisphere gyre heat transport and wind changes; alongside an increase in Antarctic sea ice during the first 250 years of meltwater forcing.
    Subject code 551
    Language English
    Publishing date 2022-01-11
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article: Transcriptomic and Genomic Testing to Guide Individualized Treatment in Chemoresistant Gastric Cancer Case.

    Moisseev, Alexey / Albert, Eugene / Lubarsky, Dan / Schroeder, David / Clark, Jeffrey

    Biomedicines

    2020  Volume 8, Issue 3

    Abstract: Gastric cancer is globally the fifth leading cause of cancer death. We present a case report describing the unique genomic characteristics of an Epstein-Barr virus-negative gastric cancer with esophageal invasion and regional lymph node metastasis. ... ...

    Abstract Gastric cancer is globally the fifth leading cause of cancer death. We present a case report describing the unique genomic characteristics of an Epstein-Barr virus-negative gastric cancer with esophageal invasion and regional lymph node metastasis. Genomic tests were performed first with the stomach biopsy using platforms FoundationOne, OncoDNA, and Oncopanel at Dana Farber Institute. Following neoadjuvant chemotherapy, residual tumor was resected and the stomach and esophageal residual tumor samples were compared with the initial biopsy by whole exome sequencing and molecular pathway analysis platform Oncobox. Copy number variation profiling perfectly matched the whole exome sequencing results. A moderate agreement was seen between the diagnostic platforms in finding mutations in the initial biopsy. Final data indicate somatic activating mutation Q546K in
    Language English
    Publishing date 2020-03-23
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines8030067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Visualization-by-Sketching: An Artist's Interface for Creating Multivariate Time-Varying Data Visualizations.

    Schroeder, David / Keefe, Daniel F

    IEEE transactions on visualization and computer graphics

    2016  Volume 22, Issue 1, Page(s) 877–885

    Abstract: We present Visualization-by-Sketching, a direct-manipulation user interface for designing new data visualizations. The goals are twofold: First, make the process of creating real, animated, data-driven visualizations of complex information more ... ...

    Abstract We present Visualization-by-Sketching, a direct-manipulation user interface for designing new data visualizations. The goals are twofold: First, make the process of creating real, animated, data-driven visualizations of complex information more accessible to artists, graphic designers, and other visual experts with traditional, non-technical training. Second, support and enhance the role of human creativity in visualization design, enabling visual experimentation and workflows similar to what is possible with traditional artistic media. The approach is to conceive of visualization design as a combination of processes that are already closely linked with visual creativity: sketching, digital painting, image editing, and reacting to exemplars. Rather than studying and tweaking low-level algorithms and their parameters, designers create new visualizations by painting directly on top of a digital data canvas, sketching data glyphs, and arranging and blending together multiple layers of animated 2D graphics. This requires new algorithms and techniques to interpret painterly user input relative to data "under" the canvas, balance artistic freedom with the need to produce accurate data visualizations, and interactively explore large (e.g., terabyte-sized) multivariate datasets. Results demonstrate a variety of multivariate data visualization techniques can be rapidly recreated using the interface. More importantly, results and feedback from artists support the potential for interfaces in this style to attract new, creative users to the challenging task of designing more effective data visualizations and to help these users stay "in the creative zone" as they work.
    MeSH term(s) Algorithms ; Art ; Climate ; Computer Graphics ; Humans ; Image Processing, Computer-Assisted/methods ; Models, Theoretical ; User-Computer Interface
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1941-0506
    ISSN (online) 1941-0506
    DOI 10.1109/TVCG.2015.2467153
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  8. Article ; Online: Pearls from a Clinician-Researcher in an Integrated Health care Delivery System.

    Ettinger, Kate Michi / Ettinger, Vivian M / Jaffe, Marc G / Schroeder, David A / Lo, Joan C

    The Permanente journal

    2021  Volume 25

    MeSH term(s) Delivery of Health Care ; Humans ; Research Personnel
    Language English
    Publishing date 2021-06-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2062823-7
    ISSN 1552-5775 ; 1552-5775
    ISSN (online) 1552-5775
    ISSN 1552-5775
    DOI 10.7812/TPP/20.305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Thesis: Four essays on investment

    Schröder, David

    2008  

    Author's details vorgelegt von David Schröder
    Keywords implied cost of capital ; Investitionsentscheidung ; Entscheidung bei Unsicherheit ; Terminplanung ; Theorie ; Eigenkapital ; Risikoprämie ; Kapitalkosten ; Finanzanalyse ; Portfolio-Management ; Börsenkurs ; Kapitaleinkommen ; Prognoseverfahren
    Language English
    Size XVI, 146 S., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Bonn, 2008
    Database ECONomics Information System

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  10. Article: Peptide stapling by late-stage Suzuki-Miyaura cross-coupling.

    Gruß, Hendrik / Feiner, Rebecca C / Mseya, Ridhiwan / Schröder, David C / Jewgiński, Michał / Müller, Kristian M / Latajka, Rafał / Marion, Antoine / Sewald, Norbert

    Beilstein journal of organic chemistry

    2022  Volume 18, Page(s) 1–12

    Abstract: The development of peptide stapling techniques to stabilise α-helical secondary structure motifs of peptides led to the design of modulators of protein-protein interactions, which had been considered undruggable for a long time. We disclose a novel ... ...

    Abstract The development of peptide stapling techniques to stabilise α-helical secondary structure motifs of peptides led to the design of modulators of protein-protein interactions, which had been considered undruggable for a long time. We disclose a novel approach towards peptide stapling utilising macrocyclisation by late-stage Suzuki-Miyaura cross-coupling of bromotryptophan-containing peptides of the catenin-binding domain of axin. Optimisation of the linker length in order to find a compromise between both sufficient linker rigidity and flexibility resulted in a peptide with an increased α-helicity and enhanced binding affinity to its native binding partner β-catenin. An increased proteolytic stability against proteinase K has been demonstrated.
    Language English
    Publishing date 2022-01-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2192461-2
    ISSN 1860-5397
    ISSN 1860-5397
    DOI 10.3762/bjoc.18.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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