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  1. Book ; Thesis: Hepatitis B in der Gravidität

    Schultz, Doreen

    retrospektive Untersuchungen im Rahmen der Mutterschaftsvorsorge im Zeitraum von 1998 bis 2012 in der Region Marburg

    2013  

    Author's details vorgelegt von Doreen Schultz
    Language German
    Size 53 Bl. : graph. Darst., Kt.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Magdeburg, Univ., Diss., 2014
    HBZ-ID HT018642676
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 E 781 order for loan Magazin

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  2. Article ; Online: mSphere of Influence: Learning Biology from the Radio.

    Schultz, Daniel

    mSphere

    2023  Volume 8, Issue 1, Page(s) e0002623

    Abstract: Daniel Schultz works at the intersection of microbiology and biological physics. In this mSphere of Influence article, he reflects on how two papers concerning the radio, "Can a biologist fix a radio? Or, what I learned while studying apoptosis" by Yuri ... ...

    Abstract Daniel Schultz works at the intersection of microbiology and biological physics. In this mSphere of Influence article, he reflects on how two papers concerning the radio, "Can a biologist fix a radio? Or, what I learned while studying apoptosis" by Yuri Lazebnik and "The evolved radio and its implications for modeling the evolution of novel sensors" by Jon Bird and Paul Layzell, offered him complementary perspectives on how to bridge the gap between engineering and biology in the study of cellular circuits.
    MeSH term(s) Apoptosis ; Biology
    Language English
    Publishing date 2023-02-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/msphere.00026-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Building Better Boyhood Programs

    Schultz, Dana / Sontag-Padilla, Lisa M

    Evaluation of Programs Funded by the African American Men and Boys Task Force Initiative

    2015  

    Keywords Management & management techniques ; Secondary schools ; Examinations & assessment ; Inclusive education / mainstreaming ; Ethnic minorities & multicultural studies ; Education ; Sociology ; Management & Organizational Behavior
    Language English
    Size 1 Online-Ressource
    Publisher RAND Corporation
    Document type Book ; Online
    Note English
    HBZ-ID HT030610355
    ISBN 9780833091659 ; 0833091654
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Apendix: Building Better Boyhood Programs

    Schultz, Dana / Sontag-Padilla, Lisa M

    Evaluation of Programs Funded by the African American Men and Boys Task Force Initiative

    2015  

    Keywords Management & management techniques ; Secondary schools ; Examinations & assessment ; Inclusive education / mainstreaming ; Ethnic minorities & multicultural studies ; Education ; Sociology ; Management & Organizational Behavior
    Language English
    Size 1 Online-Ressource
    Publisher RAND Corporation
    Document type Book ; Online
    Note English
    HBZ-ID HT030609625
    ISBN 9780833093844 ; 0833093843
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book ; Thesis: Die Anwendung schneller Neutronen in der Therapie von Tumoren der großen Speicheldrüsen

    Schultz, Dietmar

    2003  

    Author's details vorgelegt von Dietmar Schultz
    Language German
    Size 71 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Humboldt-Univ., Diss., 2003
    HBZ-ID HT013835744
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2002 MB 5583 order for loan Magazin

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  6. Article ; Online: United States Doula Programs and Their Outcomes: A Scoping Review to Inform State-Level Policies.

    Alvarado, Gabriela / Schultz, Dana / Malika, Nipher / Reed, Nastassia

    Women's health issues : official publication of the Jacobs Institute of Women's Health

    2024  

    Abstract: Background: The field of maternal health has advanced significantly over the past decades. However, the United States continues to have poor outcomes in comparison with other industrialized nations. With emerging evidence on the promise of doula care, ... ...

    Abstract Background: The field of maternal health has advanced significantly over the past decades. However, the United States continues to have poor outcomes in comparison with other industrialized nations. With emerging evidence on the promise of doula care, states are including doula care under their Medicaid programs.
    Methods: We conducted a scoping review across four academic databases and gray literature published between January 1, 2012, and March 10, 2022, to describe the landscape of literature on U.S. doula programs and their outcomes in order to inform state policy makers considering laws or programs related to doula care.
    Findings: Of 740 records identified, 100 met inclusion criteria. Outcomes fell into four areas: birthing people's outcomes, infant outcomes, systems of care and implementation, and cross-cutting issues. Data on outcomes related to doula care in the literature were predominantly clinical, even though doulas are not clinical providers. Although some studies have found associations between doula care and improved clinical outcomes for birthing people and infants, the evidence is limited due to small sample sizes, study methodology, or conflicting conclusions. Doula outcomes are underexplored in the literature, with mainly qualitative data describing low levels of diversity and equity within the doula workforce and ineffective payment models. When cost-effectiveness estimates have been calculated, they largely rely on savings realized from averted cesarean births, preterm births, and neonatal intensive care unit admissions.
    Conclusions: As state Medicaid programs expand to include doula care, policymakers should be aware of the limitations in the evidence as they plan for successful implementation, such as the narrow focus on certain clinical outcomes to quantify cost savings and conflicting conclusions on the impact of doula care. An important consideration is the impact of the reimbursement rate on the adoption of doula care, which is why it is important to engage doulas in compensation determinations, as well as the development of improved metrics to untangle the components that contribute to maternal health outcomes in the United States.
    Language English
    Publishing date 2024-05-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1085396-0
    ISSN 1878-4321 ; 1049-3867
    ISSN (online) 1878-4321
    ISSN 1049-3867
    DOI 10.1016/j.whi.2024.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3298: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Dynamical model of antibiotic responses linking expression of resistance genes to metabolism explains emergence of heterogeneity during drug exposures.

    Stevanovic, Mirjana / Teuber Carvalho, João Pedro / Bittihn, Philip / Schultz, Daniel

    Physical biology

    2024  Volume 21, Issue 3

    Abstract: Antibiotic responses in bacteria are highly dynamic and heterogeneous, with sudden exposure of bacterial colonies to high drug doses resulting in the coexistence of recovered and arrested cells. The dynamics of the response is determined by regulatory ... ...

    Abstract Antibiotic responses in bacteria are highly dynamic and heterogeneous, with sudden exposure of bacterial colonies to high drug doses resulting in the coexistence of recovered and arrested cells. The dynamics of the response is determined by regulatory circuits controlling the expression of resistance genes, which are in turn modulated by the drug's action on cell growth and metabolism. Despite advances in understanding gene regulation at the molecular level, we still lack a framework to describe how feedback mechanisms resulting from the interdependence between expression of resistance and cell metabolism can amplify naturally occurring noise and create heterogeneity at the population level. To understand how this interplay affects cell survival upon exposure, we constructed a mathematical model of the dynamics of antibiotic responses that links metabolism and regulation of gene expression, based on the tetracycline resistance
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial/genetics ; Tetracycline ; Bacteria ; Models, Theoretical
    Chemical Substances Anti-Bacterial Agents ; Tetracycline (F8VB5M810T)
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2133216-2
    ISSN 1478-3975 ; 1478-3967
    ISSN (online) 1478-3975
    ISSN 1478-3967
    DOI 10.1088/1478-3975/ad2d64
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The infant health effects of doulas: Leveraging big data and machine learning to inform cost-effective targeting.

    Peet, Evan D / Schultz, Dana / Lovejoy, Susan / Tsui, Fuchiang Rich

    Health economics

    2024  Volume 33, Issue 6, Page(s) 1387–1411

    Abstract: Doula services represent an underutilized maternal and child health intervention with the potential to improve outcomes through the provision of physical, emotional, and informational support. However, there is limited evidence of the infant health ... ...

    Abstract Doula services represent an underutilized maternal and child health intervention with the potential to improve outcomes through the provision of physical, emotional, and informational support. However, there is limited evidence of the infant health effects of doulas despite well-established connections between maternal and infant health. Moreover, because the availability of doulas is limited and often not covered by insurers, existing evidence leaves unclear if or how doula services should be allocated to achieve the greatest improvements in outcomes. We use unique data and machine learning to develop accurate predictive models of infant health and doula service participation. We then combine these predictive models within the double machine learning method to estimate the effects of doula services. We show that while doula services reduce risk on average, the benefits of doula services increase as the risk of negative infant health outcomes increases. We compare these benefits to the costs of doula services under alternative allocation schemes and show that leveraging the risk predictions dramatically increases the cost effectiveness of doula services. Our results show the potential of big data and novel analytic methods to provide cost-effective support to those at greatest risk of poor outcomes.
    MeSH term(s) Humans ; Machine Learning ; Cost-Benefit Analysis ; Infant ; Female ; Big Data ; Infant Health ; Doulas ; Infant, Newborn ; Adult
    Language English
    Publishing date 2024-03-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1135838-5
    ISSN 1099-1050 ; 1057-9230
    ISSN (online) 1099-1050
    ISSN 1057-9230
    DOI 10.1002/hec.4821
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3555: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book ; Online: Transforming Systems for Parental Depression and Early Childhood Developmental Delays

    Schultz, Dana / Reynolds, Kerry A / Sontag-Padilla, Lisa / Lovejoy, Susan L / Firth, Ray

    Findings and Lessons Learned from the Helping Families Raise Healthy Children Initiative

    2013  

    Keywords Advice on parenting ; Pregnancy, birth & baby care ; Nursing & ancillary services ; Abnormal psychology ; Sociology: birth ; Health Sciences ; Psychology ; Sociology
    Language English
    Size 1 Online-Ressource
    Publisher RAND Corporation
    Document type Book ; Online
    Note English
    HBZ-ID HT030610918
    ISBN 9780833079961 ; 0833079964
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article: Short-term evolution of antibiotic responses in highly dynamic environments favors loss of regulation.

    Crow, John / Geng, Hao / Schultz, Daniel

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Microbes inhabit natural environments that are remarkably dynamic, with sudden environmental shifts that require immediate action by the cell. To cope with changing environments, microbes are equipped with regulated response mechanisms that are only ... ...

    Abstract Microbes inhabit natural environments that are remarkably dynamic, with sudden environmental shifts that require immediate action by the cell. To cope with changing environments, microbes are equipped with regulated response mechanisms that are only activated when needed. However, when exposed to extreme environments such as clinical antibiotic treatments, complete loss of regulation is frequently observed. Although recent studies suggest that the initial evolution of microbes in new environments tends to favor mutations in regulatory pathways, it is not clear how this evolution is affected by how quickly conditions change (i.e. dynamics), or which mechanisms are commonly used to implement new regulation. Here, we perform experimental evolution on continuous cultures of
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.11.29.569327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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