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  1. Article: Nahrungsergänzungsmittel versus gesunde Nahrungsmittel – eine kontroverse Diskussion

    Schulze, Frank

    Ernährung & Medizin

    2020  Volume 35, Issue 04, Page(s) 173–179

    Abstract: Bei der Diskussion um die ggf. zusätzlich notwendige Supplementation bestimmter Nährstoffe bei bestimmten Bevölkerungsgruppen versus einer gesunden, ausgewogenen Ernährungsweise stehen sich selbst die wissenschaftlichen Meinungen kontrovers gegenüber. ... ...

    Abstract Bei der Diskussion um die ggf. zusätzlich notwendige Supplementation bestimmter Nährstoffe bei bestimmten Bevölkerungsgruppen versus einer gesunden, ausgewogenen Ernährungsweise stehen sich selbst die wissenschaftlichen Meinungen kontrovers gegenüber. Wer hat Recht, oder trifft beides zu? Dieser Beitrag unternimmt einen Versuch, Licht ins Dunkel der Positionen zu bringen.
    Language German
    Publishing date 2020-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2133391-9
    ISSN 1438-9002 ; 1439-1635
    ISSN (online) 1438-9002
    ISSN 1439-1635
    DOI 10.1055/a-1298-6184
    Database Thieme publisher's database

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  2. Book ; Thesis: Herstellung und Charakterisierung von monoklonalen Antikörpern gegen Klasse I b MHC-Moleküle der Ratte

    Schulze, Frank P.

    2003  

    Author's details vorgelegt von Frank P. Schulze
    Language German
    Size 92 Bl. : Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Med. Hochsch., Diss., 2003
    Note Enth. 2 Sonderabdr. aus: Transplantation Proceedings; Vol 22. 1990 und: Transplantation Proceedings; Vol 25. 1993
    HBZ-ID HT013899797
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 E 108 order for loan Magazin

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  3. Article ; Online: Noninfectious tissue interactions at periprosthetic interfaces.

    Schulze, Frank / Perino, Giorgio / Rakow, Anastasia / Wassilew, Georgi / Schoon, Janosch

    Orthopadie (Heidelberg, Germany)

    2023  Volume 52, Issue 3, Page(s) 186–195

    Abstract: The success of hip arthroplasty is based on modern materials in addition to the continuous development of surgical techniques and clinical experience gained over six decades. The biocompatible implant materials used in hip arthroplasty can be textured or ...

    Title translation Nichtinfektiöse Gewebsinteraktionen an den periprothetischen Interfaces.
    Abstract The success of hip arthroplasty is based on modern materials in addition to the continuous development of surgical techniques and clinical experience gained over six decades. The biocompatible implant materials used in hip arthroplasty can be textured or coated with biomimetic surfaces to ensure durable component ingrowth and moderate host response. Material integrity plays a critical role in the durability of the stable interface between implant components and periprosthetic tissues. Inflammation at the interfaces due to the release of degradation products from the implant materials is one of the causes of hip arthroplasty failure. This review summarizes the implant materials currently used in hip arthroplasty, their preclinical testing and the postoperative neogenesis of periprosthetic tissues, and the interactions of periprosthetic bone and the implant materials at the periprosthetic interfaces.
    MeSH term(s) Arthroplasty, Replacement, Hip/adverse effects ; Biocompatible Materials ; Prostheses and Implants ; Joints
    Chemical Substances Biocompatible Materials
    Language English
    Publishing date 2023-02-28
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2731-7153
    ISSN (online) 2731-7153
    DOI 10.1007/s00132-023-04352-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Ratgeber Agrarreform

    Schulze, Frank

    die wichtigsten Rechtsfragen für Landwirte, Behörden, Juristen ; Ausgleichszahlungen, Stillegungsausgleich, Bullenprämie, Mutterkuhprämie, Prämienkürzung, Subventionsbetrug

    (Top agrar aktuell)

    1995  

    Author's details Frank Schulze
    Series title Top agrar aktuell
    Keywords Europäische Union ; Agrarreform ; Agrarrecht
    Subject Landwirtschaftsrecht ; Landreform ; Agrarverfassung
    Size 346 S. : Ill.
    Edition 1. Aufl.
    Publisher Landwirtschaftsverl
    Publishing place Münster-Hiltrup
    Document type Book
    HBZ-ID HT006819923
    ISBN 3-7843-2741-9 ; 978-3-7843-2741-9
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    954/1442 available for loan (reading room) Freihandmagazin (U1)

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  5. Book ; Thesis: Differentialdiagnose akuter und chronischer pulmonaler Erkrankungen durch immunzytochemische Zellbildbetrachtungen der bronchoalveolären Lavage

    Schulze, Frank

    1994  

    Author's details vorgelegt von Frank Schulze
    Language German
    Size VIII, 112 Bl. : graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Münster (Westfalen), Univ., Diss., 1994
    Note 2 Mikrofiches
    HBZ-ID HT006502875
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1995 MB 124 order for loan Magazin

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  6. Article: Scaffold Guided Bone Regeneration for the Treatment of Large Segmental Defects in Long Bones.

    Schulze, Frank / Lang, Annemarie / Schoon, Janosch / Wassilew, Georgi I / Reichert, Johannes

    Biomedicines

    2023  Volume 11, Issue 2

    Abstract: Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous defects sometimes fail to heal. The treatment of such large segmental defects still represents a considerable clinical challenge. The regeneration of large bone ... ...

    Abstract Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous defects sometimes fail to heal. The treatment of such large segmental defects still represents a considerable clinical challenge. The regeneration of large bone defects often proves difficult, since it relies on the formation of large amounts of bone within an environment impedimental to osteogenesis, characterized by soft tissue damage and hampered vascularization. Consequently, research efforts have concentrated on tissue engineering and regenerative medical strategies to resolve this multifaceted challenge. In this review, we summarize, critically evaluate, and discuss present approaches in light of their clinical relevance; we also present future advanced techniques for bone tissue engineering, outlining the steps to realize for their translation from bench to bedside. The discussion includes the physiology of bone healing, requirements and properties of natural and synthetic biomaterials for bone reconstruction, their use in conjunction with cellular components and suitable growth factors, and strategies to improve vascularization and the translation of these regenerative concepts to in vivo applications. We conclude that the ideal all-purpose material for scaffold-guided bone regeneration is currently not available. It seems that a variety of different solutions will be employed, according to the clinical treatment necessary.
    Language English
    Publishing date 2023-01-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11020325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Impact of gadolinium-based MRI contrast agent and local anesthetics co-administration on chondrogenic gadolinium uptake and cytotoxicity.

    Zimmerer, Alexander / Schulze, Frank / Gebhardt, Sebastian / Huesker, Katrin / Stobbe, Dirk / Grolimund, Daniel / Hesse, Bernhard / Wassilew, Georgi I / Schoon, Janosch

    Heliyon

    2024  Volume 10, Issue 8, Page(s) e29719

    Abstract: The gadolinium-based contrast agent DOTA-Gd is clinically used in combination with local anesthetics for direct magnetic resonance arthrography. It remains unclear whether gadolinium uptake into cartilage is influenced by co-administration of bupivacaine ...

    Abstract The gadolinium-based contrast agent DOTA-Gd is clinically used in combination with local anesthetics for direct magnetic resonance arthrography. It remains unclear whether gadolinium uptake into cartilage is influenced by co-administration of bupivacaine or ropivacaine and whether DOTA-Gd alters their chondrotoxicity. Gadolinium quantification of chondrogenic spheroids revealed enhanced gadolinium uptake after simultaneous exposure to local anesthetics. Analyses of the spatial gadolinium distribution using synchrotron X-ray-fluorescence scanning indicates gadolinium exposed chondrocytes. In vitro exposure to DOTA-Gd does not alter viability and proliferation of human chondrocytes and the chondrotoxic potential of the anesthetics. Reduced viability induced by ropivacaine was found to be reversible, while exposure to bupivacaine leads to irreversible cell death. Our data suggest that ropivacaine is more tolerable than bupivacaine and that DOTA-Gd exposure does not alter the cytotoxicity of both anesthetics. Enhanced gadolinium uptake into cartilage due to co-administration of anesthetics should find attention.
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e29719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Conference proceedings: Knochenmark von jungen, adulten Osteotomie-Patienten als neuartige Stammzellquelle

    Schoon, Janosch / Handke, Maximilian / Schulze, Frank / Rakow, Anastasia / Wassilew, Georgi

    2023  , Page(s) AB86–3075

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2023); Berlin; ; Berufsverband für Orthopädie und Unfallchirurgie; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23dkou491
    Database German Medical Science

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  9. Book: Die Gastrointestinalflora des Schweines und ihre Regulationsmechanismen

    Schulze, Frank

    = Gastrointestinal'naja flora cvinej i mechanizmy eë reguljacii

    (Fortschrittsberichte für die Landwirtschaft und Nahrungsgüterwirtschaft ; 25,4)

    1987  

    Title variant Gastrointestinal'naja flora cvinej i mechanizmy eë reguljacii
    Author's details Frank Schulze
    Series title Fortschrittsberichte für die Landwirtschaft und Nahrungsgüterwirtschaft ; 25,4
    Collection
    Size 72 S. : Ill.
    Publisher Akad. der Landwirtschaftswiss. der Dt. Demokratischen Republik, Inst. für Landwirtschaftliche Information und Dokumentation
    Publishing place Berlin
    Publishing country XA-DDDE
    Document type Book
    Note Zsfassung in engl. und russ. Sprache
    HBZ-ID HT007138323
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    878/1758 order for loan Geschlossenes Magazin (U2)

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  10. Book ; Thesis: Kombinierte H 1 -, H 2 -Antagonisten mit Pheniramin-Struktur und anderen H 1 -affinen Bausteinen

    Schulze, Frank R.

    1991  

    Author's details vorgelegt von Frank R. Schulze
    Size 3 Mikrofiches : 24x
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Freie Univ., Diss., 1991
    Note Mikroreprod. eines Ms. Getr. Zählung: graph. Darst.
    HBZ-ID HT004450465
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1992 MB 2965 order for loan Magazin

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