LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article: Kindzentriertes Betreuungskonzept fuer Familien krebskranker Kinder in der Sterbephase. Zusammenarbeit mit dem niedergelassenen Arzt

    Schwamborn, Dorothee / Wendel, Kati

    Monatsschrift Kinderheilkunde

    1993  Volume 141, Issue 4, Page(s) 272–276

    Abstract: For a period of more than a year children with incurable diseases and their families were observed at home during the final stage of the children's illness. The psychological assistance and the necessary medical care were guaranteed by the staff of the ... ...

    Title translation Child centred plan of medical care for families of children with cancer who are at death's door. Cooperation with the general practioner
    Abstract For a period of more than a year children with incurable diseases and their families were observed at home during the final stage of the children's illness. The psychological assistance and the necessary medical care were guaranteed by the staff of the district attending clinic, the family doctors and the district home nurses. The results of this project show that the concept which takes into account the child's welfare at home, was practicable in all cases even in very serious disease right up to death.
    Keywords cancer ; case studies ; children ; home care ; death ; decision making ; pain ; parents ; patient care team ; physicians ; professional patient relationship ; psychology ; terminal care ; palliative care ; vulnerable populations
    Language German
    Document type Article
    ZDB-ID 137102-2
    ISSN 1433-0474 ; 0026-9298
    ISSN (online) 1433-0474
    ISSN 0026-9298
    Database Ethics in Medicine (ETHMED)

    More links

    Kategorien

  2. Article: TI: Kindzentriertes Betreuungskonzept fuer Familien krebskranker Kinder in der Sterbephase. Zusammenarbeit mit dem niedergelassenen Arzt

    AU: Schwamborn, Dorothee / Wendel, Kati / EDR:

    JT: Monatsschrift Kinderheilkunde

    (SE:)

    PY: 1993  Volume VOLUME / ISSUE: 141, Issue 4, Page(s) PAGINATION: 272–276

    Abstract: AB: For a period of more than a year children with incurable diseases and their families were observed at home during the final stage of the children's illness. The psychological assistance and the necessary medical care were guaranteed by the staff of ... ...

    Title translation TITLE TRANSLATION: (Child centred plan of medical care for families of children with cancer who are at death's door. Cooperation with the general practioner)
    Institution CS:
    Series title SE:
    Abstract AB: For a period of more than a year children with incurable diseases and their families were observed at home during the final stage of the children's illness. The psychological assistance and the necessary medical care were guaranteed by the staff of the district attending clinic, the family doctors and the district home nurses. The results of this project show that the concept which takes into account the child's welfare at home, was practicable in all cases even in very serious disease right up to death.
    Keywords it: cancer ; case studies ; children ; home care ; death ; decision making ; pain ; parents ; patient care team ; physicians ; professional patient relationship ; psychology ; terminal care ; palliative care ; vulnerable populations ; keyword identifiers:
    Subject code SC:
    Language Latin ; German
    Publisher PU:
    Document type Article
    Note NOTE:
    ISSN ISSN: 0026-9298
    Database Ethics in Medicine (ETHMED)

    More links

    Kategorien

  3. Article ; Online: Healthcare-associated infections in pediatric cancer patients

    Rutkowski Stefan / Schlegel Paul-Gerhardt / Gravou Chara / Schwamborn Dorothee / Wenchel Hans-Martin / Fleischhack Gudrun / Bode Udo / Ammann Roland A / Simon Arne / Dannenberg Claudia / Körholz Dieter / Laws Hans / Kramer Michael H

    BMC Infectious Diseases, Vol 8, Iss 1, p

    results of a prospective surveillance study from university hospitals in Germany and Switzerland

    2008  Volume 70

    Abstract: Abstract Background Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic. Methods Prospective multicenter surveillance for HAI and ... ...

    Abstract Abstract Background Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic. Methods Prospective multicenter surveillance for HAI and nosocomial fever of unknown origin (nFUO) with specific case definitions and standardized surveillance methods. Results 7 pediatric oncology centers (university facilities) participated from April 01, 2001 to August 31, 2005. During 54,824 days of inpatient surveillance, 727 HAIs and nFUOs were registered in 411 patients. Of these, 263 (36%) were HAIs in 181 patients, for an incidence density (ID) (number of events per 1,000 inpatient days) of 4.8 (95% CI 4.2 to 5.4; range 2.4 to 11.7; P < 0.001), and 464 (64%) were nFUO in 230 patients. Neutropenia at diagnosis correlated significantly with clinical severity of HAI. Of the 263 HAIs, 153 (58%) were bloodstream infections (BSI). Of the 138 laboratory-confirmed BSIs, 123 (89%) were associated with use of a long-term central venous catheter (CVAD), resulting in an overall ID of 2.8 per 1,000 utilization days (95% CI 2.3 to 3.3). The ID was significantly lower in Port-type than in Hickman-type CVADs. The death of 8 children was related to HAI, including six cases of aspergillosis. The attributable mortality was 3.0% without a significant association to neutropenia at time of NI diagnosis. Conclusion Our study confirmed that pediatric cancer patients are at an increased risk for specific HAIs. The prospective surveillance of HAI and comparison with cumulative multicenter results are indispensable for targeted prevention of these adverse events of anticancer treatment.
    Keywords Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Infectious and parasitic diseases ; RC109-216
    Subject code 610
    Language English
    Publishing date 2008-05-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  4. Article ; Online: Healthcare-associated infections in pediatric cancer patients: results of a prospective surveillance study from university hospitals in Germany and Switzerland.

    Simon, Arne / Ammann, Roland A / Bode, Udo / Fleischhack, Gudrun / Wenchel, Hans-Martin / Schwamborn, Dorothee / Gravou, Chara / Schlegel, Paul-Gerhardt / Rutkowski, Stefan / Dannenberg, Claudia / Körholz, Dieter / Laws, Hans Jürgen / Kramer, Michael H

    BMC infectious diseases

    2008  Volume 8, Page(s) 70

    Abstract: Background: Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic.: Methods: Prospective multicenter surveillance for HAI and ... ...

    Abstract Background: Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic.
    Methods: Prospective multicenter surveillance for HAI and nosocomial fever of unknown origin (nFUO) with specific case definitions and standardized surveillance methods.
    Results: 7 pediatric oncology centers (university facilities) participated from April 01, 2001 to August 31, 2005. During 54,824 days of inpatient surveillance, 727 HAIs and nFUOs were registered in 411 patients. Of these, 263 (36%) were HAIs in 181 patients, for an incidence density (ID) (number of events per 1,000 inpatient days) of 4.8 (95% CI 4.2 to 5.4; range 2.4 to 11.7; P < 0.001), and 464 (64%) were nFUO in 230 patients. Neutropenia at diagnosis correlated significantly with clinical severity of HAI. Of the 263 HAIs, 153 (58%) were bloodstream infections (BSI). Of the 138 laboratory-confirmed BSIs, 123 (89%) were associated with use of a long-term central venous catheter (CVAD), resulting in an overall ID of 2.8 per 1,000 utilization days (95% CI 2.3 to 3.3). The ID was significantly lower in Port-type than in Hickman-type CVADs. The death of 8 children was related to HAI, including six cases of aspergillosis. The attributable mortality was 3.0% without a significant association to neutropenia at time of NI diagnosis.
    Conclusion: Our study confirmed that pediatric cancer patients are at an increased risk for specific HAIs. The prospective surveillance of HAI and comparison with cumulative multicenter results are indispensable for targeted prevention of these adverse events of anticancer treatment.
    MeSH term(s) Adolescent ; Bacteremia/epidemiology ; Bacteremia/microbiology ; Bacteremia/mortality ; Catheterization, Central Venous/adverse effects ; Catheterization, Central Venous/statistics & numerical data ; Child ; Child, Preschool ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Cross Infection/mortality ; Fever of Unknown Origin/epidemiology ; Fever of Unknown Origin/microbiology ; Fever of Unknown Origin/mortality ; Germany/epidemiology ; Hospitals, University ; Humans ; Incidence ; Infant ; Infections/epidemiology ; Infections/microbiology ; Infections/mortality ; Neoplasms/complications ; Neutropenia/complications ; Population Surveillance/methods ; Risk Factors ; Severity of Illness Index ; Switzerland/epidemiology
    Language English
    Publishing date 2008-05-23
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ISSN 1471-2334
    ISSN (online) 1471-2334
    DOI 10.1186/1471-2334-8-70
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Hochdosierte Chemotherapie: Grundlagen, Indikationen, Komplikationen

    Göbel, Ulrich / Jürgens, Herbert / Schwamborn, Dorothee / Wahn, Volker

    Klinische Pädiatrie

    1988  Volume 200, Issue 01, Page(s) 1–6

    Abstract: Cure rates of children and adolescents with malignant diseases have improved since the introduction of systemic chemotherapy in cooperative trials in the recent 10 to 15 years. Tumors resistant to conventional doses have responded to high dose regimens. ... ...

    Abstract Cure rates of children and adolescents with malignant diseases have improved since the introduction of systemic chemotherapy in cooperative trials in the recent 10 to 15 years. Tumors resistant to conventional doses have responded to high dose regimens. The rationale for the use of high dose regimens is discussed as well as adequate methods of protecting against severe and often life threatening complications.
    Language German
    Publishing date 1988-01-01
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 120650-3
    ISSN 1439-3824 ; 0300-8630
    ISSN (online) 1439-3824
    ISSN 0300-8630
    DOI 10.1055/s-2008-1033675
    Database Thieme publisher's database

    More links

    Kategorien

  6. Article: Klinische Erfahrungen mit polyäthylenglykol-gekoppelter E. coli-L-Asparaginase bei Patienten mit ALL-Mehrfachrezidiv

    Jürgens, H. / Schwamborn, Dorothee / Körholz, D. / Wahn, V. / Göbel, U.

    Klinische Pädiatrie

    1988  Volume 200, Issue 03, Page(s) 184–189

    Abstract: The efficiency and toxicity of E. coli-L-Asparaginase coupled to polyethylenglycol (PEGASP) was investigated in 5 patients with second relapse of acute lymphoblastic leukemia. PEG-ASP was administered at a dose of 2000 U/m 2 as infusion over 2 hrs. every ...

    Abstract The efficiency and toxicity of E. coli-L-Asparaginase coupled to polyethylenglycol (PEGASP) was investigated in 5 patients with second relapse of acute lymphoblastic leukemia. PEG-ASP was administered at a dose of 2000 U/m 2 as infusion over 2 hrs. every 2 weeks. Following an initial single agent phase, PEG-ASP was combined with prednisone, vincristine, adriamycin and methotrexate i.t. Following induction, all 5 patients were in third remission. The remissions lasted from 3 to 9 months, median 4 months. The toxicity was transient and mild. Also in patients sensitized against native L-Asparaginase no anaphylactic reactions were observed.
    Language German
    Publishing date 1988-05-01
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 120650-3
    ISSN 1439-3824 ; 0300-8630
    ISSN (online) 1439-3824
    ISSN 0300-8630
    DOI 10.1055/s-2008-1033707
    Database Thieme publisher's database

    More links

    Kategorien

To top