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  1. Book ; Online ; E-Book: A multidisciplinary approach to obstetric fistula in Africa

    Drew, Laura Briggs / Ruder, Bonnie / Schwartz, David A.

    public health, anthropological, and medical perspectives

    (Global Maternal and Child Health)

    2022  

    Author's details edited by Laura Briggs Drew, Bonnie Ruder, David A. Schwartz
    Series title Global Maternal and Child Health
    Keywords Fistula
    Subject code 910.5
    Language English
    Size 1 online resource (492 pages)
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-031-06314-7 ; 9783031063138 ; 978-3-031-06314-5 ; 3031063139
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Perianal Fistulas in Patients With Crohn's Disease.

    Schwartz, David A

    Gastroenterology & hepatology

    2024  Volume 20, Issue 4, Page(s) 237–240

    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Top tips for endoscopic balloon dilation of Crohn's-related strictures (with video).

    Schwartz, David A

    Gastrointestinal endoscopy

    2023  Volume 97, Issue 5, Page(s) 974–976

    MeSH term(s) Humans ; Constriction, Pathologic/etiology ; Constriction, Pathologic/therapy ; Dilatation ; Crohn Disease/complications ; Crohn Disease/therapy ; Endoscopy ; Treatment Outcome ; Intestinal Obstruction ; Endoscopy, Gastrointestinal
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Video-Audio Media ; Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.01.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Medicine science and dreams

    Schwartz, David A.

    the making of physician-scientists

    (Biomedicine)

    2011  

    Author's details David A. Schwartz ed
    Series title Biomedicine
    Language English
    Size XXXIX, 334 S. : Ill.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT016617670
    ISBN 978-90-481-9537-4 ; 9789048195381 ; 90-481-9537-3 ; 9048195381
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Stillbirth after COVID-19 in Unvaccinated Mothers Can Result from SARS-CoV-2 Placentitis, Placental Insufficiency, and Hypoxic Ischemic Fetal Demise, Not Direct Fetal Infection: Potential Role of Maternal Vaccination in Pregnancy.

    Schwartz, David A

    Viruses

    2022  Volume 14, Issue 3

    Abstract: Stillbirth is a recently recognized complication of COVID-19 in pregnant women. Other congenitally transmitted infections from viruses, bacteria and parasites can cause stillbirth by infecting fetal organs following transplacental transmission of the ... ...

    Abstract Stillbirth is a recently recognized complication of COVID-19 in pregnant women. Other congenitally transmitted infections from viruses, bacteria and parasites can cause stillbirth by infecting fetal organs following transplacental transmission of the agent from the maternal bloodstream. However, recent research on pregnant women with COVID-19 having stillbirths indicates that there is another mechanism of stillbirth that can occur in placentas infected with SARS-CoV-2. In these cases, viral infection of the placenta results in SARS-CoV-2 placentitis, a combination of concurrent destructive findings that include increased fibrin deposition which typically reaches the level of massive perivillous fibrin deposition, chronic histiocytic intervillositis and trophoblast necrosis. These three pathological lesions, in some cases together with placental hemorrhage, thrombohematomas and villitis, result in severe and diffuse placental parenchymal destruction. This pathology can involve greater than one-half of the placental volume, averaging 77% in the largest study of 68 cases, effectively rendering the placenta incapable of performing its function of oxygenating the fetus. This destructive placental process can lead to stillbirth and neonatal death via malperfusion and placental insufficiency which is independent of fetal infection. Fetal autopsies show no evidence that direct infection of fetal organs is contributory. Because all mothers examined have been unvaccinated, maternal vaccination may prevent viremia and consequent placental infection.
    MeSH term(s) COVID-19/prevention & control ; Female ; Fetal Death/etiology ; Humans ; Infant, Newborn ; Mothers ; Placenta/pathology ; Placental Insufficiency/pathology ; Pregnancy ; SARS-CoV-2 ; Stillbirth ; Vaccination/adverse effects
    Language English
    Publishing date 2022-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14030458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online ; E-Book: Pregnant in the time of Ebola

    Schwartz, David A. / Anoko, Julienne N. / Abramowitz, Sharon Alane

    women and their children in the 2013-2015 West African epidemic

    (Global maternal and child health: medical, anthropological, and public health perspectives)

    2019  

    Series title Global maternal and child health: medical, anthropological, and public health perspectives
    Subject code 610
    Language English
    Size 1 Online-Ressource (xxix, 487 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019953324
    ISBN 978-3-319-97637-2 ; 9783319976365 ; 3-319-97637-0 ; 3319976362
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Article ; Online: In Reply.

    Schwartz, David A

    Archives of pathology & laboratory medicine

    2021  Volume 145, Issue 8, Page(s) 921–922

    Language English
    Publishing date 2021-05-02
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/arpa.2021-0170-LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Mpox (Monkeypox) in Pregnancy: Viral Clade Differences and Their Associations with Varying Obstetrical and Fetal Outcomes.

    Schwartz, David A / Pittman, Phillip R

    Viruses

    2023  Volume 15, Issue 8

    Abstract: In African countries where mpox (monkeypox) is endemic, infection is caused by two genetically related clades-Clade I (formerly Congo Basin), and Clade IIa (formerly West Africa), both of which are potentially life-threatening infections. Prior to the ... ...

    Abstract In African countries where mpox (monkeypox) is endemic, infection is caused by two genetically related clades-Clade I (formerly Congo Basin), and Clade IIa (formerly West Africa), both of which are potentially life-threatening infections. Prior to the 2022-2023 global outbreak, mpox infections among pregnant women caused by Clade I were reported to have a 75% perinatal case fatality rate in the Democratic Republic of Congo, including the only documented case of placental infection and stillbirth from the Congenital Mpox Syndrome, and the Clade IIa mpox infection was associated with stillbirths in Nigeria. The 2022-2023 global mpox outbreak, caused by a genetically distinct strain, Clade IIb, has focused attention on the effects of mpox on pregnant women and fetal outcomes. There have been at least 58 cases of mpox infection occurring in pregnant women during the 2022-2023 outbreak. No confirmed cases of adverse perinatal outcome, including stillbirth, have been reported. The absence of perinatal morbidity and mortality from Clade IIb corresponds to the overall case fatality rate among non-pregnant women of <0.1%, as this clade has been demonstrated to produce a less-severe disease than the mpox Clade I or IIa variants. Thus, there are apparently important differences between mpox clades affecting pregnant women and perinatal outcomes.
    MeSH term(s) Pregnancy ; Female ; Humans ; Mpox (monkeypox)/epidemiology ; Stillbirth/epidemiology ; Placenta ; Fetus ; Nigeria
    Language English
    Publishing date 2023-07-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15081649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Stillbirth after COVID-19 in Unvaccinated Mothers Can Result from SARS-CoV-2 Placentitis, Placental Insufficiency, and Hypoxic Ischemic Fetal Demise, Not Direct Fetal Infection: Potential Role of Maternal Vaccination in Pregnancy

    Schwartz, David A.

    Viruses. 2022 Feb. 23, v. 14, no. 3

    2022  

    Abstract: Stillbirth is a recently recognized complication of COVID-19 in pregnant women. Other congenitally transmitted infections from viruses, bacteria and parasites can cause stillbirth by infecting fetal organs following transplacental transmission of the ... ...

    Abstract Stillbirth is a recently recognized complication of COVID-19 in pregnant women. Other congenitally transmitted infections from viruses, bacteria and parasites can cause stillbirth by infecting fetal organs following transplacental transmission of the agent from the maternal bloodstream. However, recent research on pregnant women with COVID-19 having stillbirths indicates that there is another mechanism of stillbirth that can occur in placentas infected with SARS-CoV-2. In these cases, viral infection of the placenta results in SARS-CoV-2 placentitis, a combination of concurrent destructive findings that include increased fibrin deposition which typically reaches the level of massive perivillous fibrin deposition, chronic histiocytic intervillositis and trophoblast necrosis. These three pathological lesions, in some cases together with placental hemorrhage, thrombohematomas and villitis, result in severe and diffuse placental parenchymal destruction. This pathology can involve greater than one-half of the placental volume, averaging 77% in the largest study of 68 cases, effectively rendering the placenta incapable of performing its function of oxygenating the fetus. This destructive placental process can lead to stillbirth and neonatal death via malperfusion and placental insufficiency which is independent of fetal infection. Fetal autopsies show no evidence that direct infection of fetal organs is contributory. Because all mothers examined have been unvaccinated, maternal vaccination may prevent viremia and consequent placental infection.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; blood flow ; death ; fetal death ; fetus ; fibrin ; hemorrhage ; necrosis ; pregnancy ; transplacental transmission ; trophoblast ; vaccination ; viremia
    Language English
    Dates of publication 2022-0223
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14030458
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Being Pregnant during the Kivu Ebola Virus Outbreak in DR Congo: The rVSV-ZEBOV Vaccine and Its Accessibility by Mothers and Infants during Humanitarian Crises and in Conflict Areas.

    Schwartz, David A

    Vaccines

    2020  Volume 8, Issue 1

    Abstract: The Ebola virus disease (EVD) outbreak that began in Kivu province of the Democratic Republic of the Congo (DRC) in July 2018 is the second largest in history. It is also the largest and most deadly of the ten Ebola outbreaks to occur in DRC, the country ...

    Abstract The Ebola virus disease (EVD) outbreak that began in Kivu province of the Democratic Republic of the Congo (DRC) in July 2018 is the second largest in history. It is also the largest and most deadly of the ten Ebola outbreaks to occur in DRC, the country where Ebola was first identified during the 1976 Yambuku outbreak. The Kivu region is one of the most challenging locations in which to organize humanitarian assistance. It is an active conflict zone in which numerous armed groups are conducting violent acts, often directed against the inhabitants, healthcare and relief workers and peacekeepers. EVD has been especially problematic in pregnancy-previous outbreaks both in DRC and other countries have resulted in very high mortality rates among pregnant women and especially their infants, with maternal mortality in some outbreaks reaching over 90% and perinatal mortality 100%. The development and implementation of the Merck rVSV-ZEBOV vaccine for Ebola infection has been a tremendous public health advance in preventing EVD, being used successfully in both the West Africa Ebola epidemic and the Équateur DRC Ebola outbreak. But from the start of the Kivu outbreak, policy decisions had resulted in excluding pregnant and lactating women and their infants from receiving it during extensive ring vaccination efforts. In June 2019, this policy was reversed, 10 months after the start of the outbreak. Pregnant and lactating women are now permitted not only the rVSV-ZEBOV vaccine in the continuing Kivu outbreak but also the newly implemented Ad26.ZEBOV/MVA-BN vaccine.
    Language English
    Publishing date 2020-01-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines8010038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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