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  1. Book ; Thesis: The role of the IL-33-ST2 axis in acute graft-versus-host disease

    Schwarze, Vincent

    2013  

    Author's details vorgelegt von Vincent Schwarze
    Language English
    Size 132 Bl. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Freiburg (Breisgau), Univ., Diss., 2014
    HBZ-ID HT018615338
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 E 635 order for loan Magazin

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  2. Article ; Online: Authors' Response to Letter: "Diagnosis of Hepatic Hydatid Cysts by Contrast-Enhanced Ultrasound".

    Schwarze, Vincent

    Ultraschall in der Medizin (Stuttgart, Germany : 1980)

    2019  Volume 41, Issue 6, Page(s) 700

    MeSH term(s) Echinococcosis, Hepatic/diagnostic imaging ; Humans ; Ultrasonography
    Language English
    Publishing date 2019-10-24
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 801064-x
    ISSN 1438-8782 ; 1439-0914 ; 1431-4894 ; 0172-4614
    ISSN (online) 1438-8782
    ISSN 1439-0914 ; 1431-4894 ; 0172-4614
    DOI 10.1055/a-1024-2487
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1572: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Book ; Online ; Thesis: Interdisziplinäre Anwendungen des kontrastmittelverstärkten Ultraschalls (CEUS) im diagnostischen Algorithmus selektierter Fragestellungen

    Schwarze, Vincent [Verfasser]

    2021  

    Author's details Vincent Schwarze
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
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  4. Article: Authors’ Response to Letter: “Diagnosis of Hepatic Hydatid Cysts by Contrast-Enhanced Ultrasound”

    Schwarze, Vincent

    Ultraschall in der Medizin - European Journal of Ultrasound

    2019  Volume 41, Issue 06, Page(s) 700–700

    Language English
    Publishing date 2019-10-24
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 801064-x
    ISSN 1438-8782 ; 0172-4614 ; 1439-0914 ; 1431-4894
    ISSN (online) 1438-8782
    ISSN 0172-4614 ; 1439-0914 ; 1431-4894
    DOI 10.1055/a-1024-2487
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1572: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Artificial intelligence support in MR imaging of incidental renal masses: an early health technology assessment.

    Marka, Alexander W / Luitjens, Johanna / Gassert, Florian T / Steinhelfer, Lisa / Burian, Egon / Rübenthaler, Johannes / Schwarze, Vincent / Froelich, Matthias F / Makowski, Marcus R / Gassert, Felix G

    European radiology

    2024  

    Abstract: Objective: This study analyzes the potential cost-effectiveness of integrating an artificial intelligence (AI)-assisted system into the differentiation of incidental renal lesions as benign or malignant on MR images during follow-up.: Materials and ... ...

    Abstract Objective: This study analyzes the potential cost-effectiveness of integrating an artificial intelligence (AI)-assisted system into the differentiation of incidental renal lesions as benign or malignant on MR images during follow-up.
    Materials and methods: For estimation of quality-adjusted life years (QALYs) and lifetime costs, a decision model was created, including the MRI strategy and MRI + AI strategy. Model input parameters were derived from recent literature. Willingness to pay (WTP) was set to $100,000/QALY. Costs of $0 for the AI were assumed in the base-case scenario. Model uncertainty and costs of the AI system were assessed using deterministic and probabilistic sensitivity analysis.
    Results: Average total costs were at $8054 for the MRI strategy and $7939 for additional use of an AI-based algorithm. The model yielded a cumulative effectiveness of 8.76 QALYs for the MRI strategy and of 8.77 for the MRI + AI strategy. The economically dominant strategy was MRI + AI. Deterministic and probabilistic sensitivity analysis showed high robustness of the model with the incremental cost-effectiveness ratio (ICER), which represents the incremental cost associated with one additional QALY gained, remaining below the WTP for variation of the input parameters. If increasing costs for the algorithm, the ICER of $0/QALY was exceeded at $115, and the defined WTP was exceeded at $667 for the use of the AI.
    Conclusions: This analysis, rooted in assumptions, suggests that the additional use of an AI-based algorithm may be a potentially cost-effective alternative in the differentiation of incidental renal lesions using MRI and needs to be confirmed in the future.
    Clinical relevance statement: These results hint at AI's the potential impact on diagnosing renal masses. While the current study urges careful interpretation, ongoing research is essential to confirm and seamlessly integrate AI into clinical practice, ensuring its efficacy in routine diagnostics.
    Key points: • This is a model-based study using data from literature where AI has been applied in the diagnostic workup of incidental renal lesions. • MRI + AI has the potential to be a cost-effective alternative in the differentiation of incidental renal lesions. • The additional use of AI can reduce costs in the diagnostic workup of incidental renal lesions.
    Language English
    Publishing date 2024-02-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-024-10643-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3300: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Book ; Online ; Thesis: Möglichkeiten des kontrastverstärkten Ultraschalls (CEUS) in radiologischen Anwendungsgebieten

    Schwarze, Vincent [Verfasser] / Rübenthaler, Johannes [Akademischer Betreuer]

    2021  

    Author's details Vincent Schwarze ; Betreuer: Johannes Rübenthaler
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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    Inter-library loan at ZB MED

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  7. Article: Diagnostic Value of Contrast-Enhanced Ultrasound for Evaluation of Transjugular Intrahepatic Portosystemic Shunt Perfusion.

    Marschner, Constantin A / Geyer, Thomas / Froelich, Matthias F / Rübenthaler, Johannes / Schwarze, Vincent / Clevert, Dirk-André

    Diagnostics (Basel, Switzerland)

    2021  Volume 11, Issue 9

    Abstract: Background: In patients with liver cirrhosis, transjugular intrahepatic portosystemic shunt (TIPS) displays an effective method for treating portal hypertension. Main indications include refractory ascites and secondary prevention of esophageal bleeding. ...

    Abstract Background: In patients with liver cirrhosis, transjugular intrahepatic portosystemic shunt (TIPS) displays an effective method for treating portal hypertension. Main indications include refractory ascites and secondary prevention of esophageal bleeding. Color Doppler ultrasound (CDUS) plays a leading role in the follow-up management, whereas contrast-enhanced ultrasound (CEUS) is not routinely considered. We compared the efficacy of CEUS to CDUS and highlighted differences compared to findings of corresponding computed tomography (CT) and magnetic resonance imaging (MRI). (2) Methods: On a retrospective basis, 106 patients with CEUS examination after TIPS were included. The enrollment period was 12 years (between 2008 and 2020) and the age group ranged from 23.3 to 82.1 years. In addition, 92 CDUS, 43 CT and 58 MRI scans were evaluated for intermodal comparison. (3) Results: Intermodal analysis and comparison revealed a high level of concordance between CDUS, CT and MRI in the vast majority of cases. In comparison to CDUS, the correlation of the relevant findings was 92.5%, 95.3% for CT and 87.9% for MRI. In some cases, however, additional information was provided by CEUS (4) Conclusions: CEUS depicts a safe and effective imaging modality for follow-up after TIPS. In addition to CDUS, CEUS enables specific assessment of stent pathologies and stent dysfunction due to its capacity to dynamically visualize single microbubbles at high spatial and temporal resolution. Due to the low number of adverse events regarding the application of contrast agents, CEUS can be administered to a very broad patient population, thus avoiding additional radiation exposure compared to CT angiography in cases with divergent findings during follow-up.
    Language English
    Publishing date 2021-09-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics11091593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Therapeutic Outcome of MR-Guided High-Intensity Focused Ultrasound (MR-HIFU) in Solitary versus Multiple Uterine Fibroids.

    Erber, Bernd / Schwarze, Vincent / Strobl, Frederik / Burges, Alexander / Mahner, Sven / Goller, Sophia Samira / Rudolph, Jan / Ricke, Jens / Sabel, Bastian Oliver

    Healthcare (Basel, Switzerland)

    2022  Volume 10, Issue 8

    Abstract: MR-guided high-intensity focused ultrasound (MR-HIFU) is an effective method for treating symptomatic uterine fibroids, especially solitary lesions. The aim of our study was to compare the clinical and morphological outcomes of patients who underwent MR- ... ...

    Abstract MR-guided high-intensity focused ultrasound (MR-HIFU) is an effective method for treating symptomatic uterine fibroids, especially solitary lesions. The aim of our study was to compare the clinical and morphological outcomes of patients who underwent MR-HIFU due to solitary fibroid (SF) or multiple fibroids (MFs) in a prospective clinical trial. We prospectively included 21 consecutive patients with SF (10) and MF (11) eligible for MR-guided HIFU. The morphological data were assessed using mint Lesion™ for MRI. The clinical data were determined using the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire before and 6 months after treatment. Unpaired and paired Wilcoxon-test and
    Language English
    Publishing date 2022-08-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare10081471
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  9. Article ; Online: Nonradiology Health-Care Professionals Significantly Benefit From AI Assistance in Emergency-Related Chest Radiography Interpretation.

    Rudolph, Jan / Huemmer, Christian / Preuhs, Alexander / Buizza, Guiulia / Hoppe, Boj F / Dinkel, Julien / Koliogiannis, Vanessa / Fink, Nicola / Goller, Sophia S / Schwarze, Vincent / Mansour, Nabeel / Schmidt, Vanessa F / Fischer, Maximilian / Jörgens, Maximilian / Ben Khaled, Najib / Liebig, Thomas / Ricke, Jens / Rueckel, Johannes / Sabel, Bastian O

    Chest

    2024  

    Abstract: Background: Chest radiographs (CXRs) are still of crucial importance in primary diagnostics, but their interpretation poses difficulties at times.: Research question: Can a convolutional neural network-based artificial intelligence (AI) system that ... ...

    Abstract Background: Chest radiographs (CXRs) are still of crucial importance in primary diagnostics, but their interpretation poses difficulties at times.
    Research question: Can a convolutional neural network-based artificial intelligence (AI) system that interprets CXRs add value in an emergency unit setting?
    Study design and methods: A total of 563 CXRs acquired in the emergency unit of a major university hospital were retrospectively assessed twice by three board-certified radiologists, three radiology residents, and three emergency unit-experienced nonradiology residents (NRRs). They used a two-step reading process: (1) without AI support (woAI); and (2) with AI support (wAI) providing additional images with AI overlays. Suspicion of four suspected pathologies (pleural effusion, pneumothorax, consolidations suspicious for pneumonia, and nodules) was reported on a five-point confidence scale. Confidence scores of the board-certified radiologists were converted into four binary reference standards (RFS I-IV) of different sensitivities. Performance by radiology residents and NRRs woAI/wAI were statistically compared by using receiver-operating characteristics (ROCs), Youden statistics, and operating point metrics derived from fitted ROC curves.
    Results: NRRs could significantly improve performance, sensitivity, and accuracy wAI in all four pathologies tested. In the most sensitive RFS IV, NRR consensus improved the area under the ROC curve (mean, 95% CI) in the detection of the time-critical pathology pneumothorax from 0.846 (0.785-0.907) woAI to 0.974 (0.947-1.000) wAI (P < .001), which represented a gain of 30% in sensitivity and 2% in accuracy (while maintaining an optimized specificity). The most pronounced effect was observed in nodule detection, with NRR wAI improving sensitivity by 53% and accuracy by 7% (area under the ROC curve woAI, 0.723 [0.661-0.785]; wAI, 0.890 [0.848-0.931]; P < .001). The RR consensus wAI showed smaller, mostly nonsignificant gains in performance, sensitivity, and accuracy.
    Interpretation: In an emergency unit setting without 24/7 radiology coverage, the presented AI solution features an excellent clinical support tool to nonradiologists, similar to a second reader, and allows for a more accurate primary diagnosis and thus earlier therapy initiation.
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2024.01.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Benefits of contrast-enhanced ultrasonography for interventional procedures.

    Marschner, Constantin Arndt / Rübenthaler, Johannes / Froelich, Matthias Frank / Schwarze, Vincent / Clevert, Dirk-André

    Ultrasonography (Seoul, Korea)

    2020  Volume 40, Issue 2, Page(s) 207–216

    Abstract: For evaluating unclear tumorous lesions, contrast-enhanced ultrasonography (CEUS) is an important imaging modality in addition to contrast-enhanced computed tomography and magnetic resonance imaging, and may provide valuable insights into the ... ...

    Abstract For evaluating unclear tumorous lesions, contrast-enhanced ultrasonography (CEUS) is an important imaging modality in addition to contrast-enhanced computed tomography and magnetic resonance imaging, and may provide valuable insights into the microvascularization of tumors in dynamic examinations. In interventional procedures, CEUS can make a valuable contribution in pre-, peri-, and post-interventional settings, reduce radiation exposure and, under certain circumstances, decrease the number of interventions needed for patients.
    Language English
    Publishing date 2020-11-19
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2775801-1
    ISSN 2288-5943 ; 2288-5919
    ISSN (online) 2288-5943
    ISSN 2288-5919
    DOI 10.14366/usg.20083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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