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  1. Article ; Online: How kidney function adapts to changes in acid-base balance: the AE4 transporter as a central acid-base sensor in tubular cells.

    Schweda, Frank

    Pflugers Archiv : European journal of physiology

    2023  Volume 476, Issue 1, Page(s) 7–8

    MeSH term(s) Acid-Base Equilibrium ; Kidney/metabolism ; Membrane Transport Proteins/metabolism ; Epithelial Cells
    Chemical Substances Membrane Transport Proteins
    Language English
    Publishing date 2023-12-20
    Publishing country Germany
    Document type Editorial
    ZDB-ID 6380-0
    ISSN 1432-2013 ; 0031-6768
    ISSN (online) 1432-2013
    ISSN 0031-6768
    DOI 10.1007/s00424-023-02898-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.35: Show issues Location:
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  2. Book ; Online: Laborhandbuch Nierenperfusion

    Schurek, Hans-Joachim / Neumann, Klaus Hinrich / Schweda, Frank

    (Wissenschaftliche Schriften der WWU Münster. Reihe V ; Band 5 ; MV Wissenschaft)

    2015  

    Author's details Hans-Joachim Schurek unter Mitarbeit von Klaus Hinrich Neumann und Frank Schweda
    Series title Wissenschaftliche Schriften der WWU Münster. Reihe V ; Band 5
    MV Wissenschaft
    Wissenschaftliche Schriften der WWU Münster
    Collection Wissenschaftliche Schriften der WWU Münster
    Keywords Nierenperfusion
    Subject Niere
    Language German
    Size 1 Online-Ressource (227 Seiten), Illustrationen, Diagramme
    Publisher Verlagshaus Monsenstein und Vannerdat
    Publishing place Münster
    Publishing country Germany
    Document type Book ; Online
    HBZ-ID HT018875172
    ISBN 9783840501326 ; 3840501326
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Laborhandbuch Nierenperfusion

    Schurek, Hans-Joachim / Neumann, Klaus Hinrich / Schweda, Frank

    (Wissenschaftliche Schriften der WWU Münster. Reihe V ; Band 5 ; MV Wissenschaft)

    2015  

    Author's details Hans-Joachim Schurek unter Mitarbeit von Klaus Hinrich Neumann und Frank Schweda
    Series title Wissenschaftliche Schriften der WWU Münster. Reihe V ; Band 5
    MV Wissenschaft
    Wissenschaftliche Schriften der WWU Münster
    Collection Wissenschaftliche Schriften der WWU Münster
    Keywords Nierenperfusion
    Subject Niere
    Language German
    Size X, 227 Seiten, Illustrationen, Diagramme
    Publisher Verlagshaus Monsenstein und Vannerdat
    Publishing place Münster
    Publishing country Germany
    Document type Book
    HBZ-ID HT018937156
    ISBN 978-3-8405-0132-6 ; 3-8405-0132-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 A 841 available for loan (reading room) Lesesaal EG

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  4. Book ; Online: A laboratory manual of kidney perfusion techniques

    Schurek, Hans-Joachim / Neumann, Klaus Hinrich / Schweda, Frank / Czogalla, Jan

    (Wissenschaftliche Schriften der WWU Münster. Reihe V ; Band 6)

    2017  

    Author's details Hans-Joachim Schurek in collaboration with Klaus Hinrich Neumann, Frank Schweda and Jan Czogalla
    Series title Wissenschaftliche Schriften der WWU Münster. Reihe V ; Band 6
    Wissenschaftliche Schriften der WWU Münster
    Collection Wissenschaftliche Schriften der WWU Münster
    Keywords Nierenperfusion
    Subject Niere
    Language English
    Size 1 Online-Ressource (VIII, 228 Seiten), Illustrationen, Diagramme
    Publisher MV Wissenschaft
    Publishing place Münster
    Publishing country Germany
    Document type Book ; Online
    HBZ-ID HT019422579
    ISBN 9783840501548 ; 3840501547
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book: A laboratory manual of kidney perfusion techniques

    Schurek, Hans-Joachim / Neumann, Klaus Hinrich / Schweda, Frank / Czogalla, Jan

    (Wissenschaftliche Schriften der WWU Münster. Reihe V ; Band 6)

    2017  

    Author's details Hans-Joachim Schurek in collaboration with Klaus Hinrich Neumann, Frank Schweda and Jan Czogalla
    Series title Wissenschaftliche Schriften der WWU Münster. Reihe V ; Band 6
    Wissenschaftliche Schriften der WWU Münster
    Collection Wissenschaftliche Schriften der WWU Münster
    Keywords Nierenperfusion
    Subject Niere
    Language English
    Size VIII, 228 Seiten, Illustrationen, Diagramme
    Publisher MV Wissenschaft
    Publishing place Münster
    Publishing country Germany
    Document type Book
    HBZ-ID HT019422734
    ISBN 978-3-8405-0154-8 ; 3-8405-0154-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 C 72 order for loan Magazin

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  6. Book ; Thesis: Tierexperimenteller Vergleich der Linksherz-Assist-Systeme Intraaortale Ballonpumpe und Hemopump in der akuten Myokardischämie

    Schweda, Frank

    1997  

    Author's details vorgelegt von Frank Schweda
    Language German
    Size 92 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Göttingen, Univ., Diss., 1998
    HBZ-ID HT013149481
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 MB 2024 order for loan Magazin

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  7. Article ; Online: Impact of Impaired Kidney Function on Arrhythmia-Promoting Cardiac Ion Channel Regulation.

    Sinha, Frederick / Schweda, Frank / Maier, Lars S / Wagner, Stefan

    International journal of molecular sciences

    2023  Volume 24, Issue 18

    Abstract: Chronic kidney disease (CKD) is associated with a significantly increased risk of cardiovascular events and sudden cardiac death. Although arrhythmias are one of the most common causes of sudden cardiac death in CKD patients, the molecular mechanisms ... ...

    Abstract Chronic kidney disease (CKD) is associated with a significantly increased risk of cardiovascular events and sudden cardiac death. Although arrhythmias are one of the most common causes of sudden cardiac death in CKD patients, the molecular mechanisms involved in the development of arrhythmias are still poorly understood. In this narrative review, therefore, we summarize the current knowledge on the regulation of cardiac ion channels that contribute to arrhythmia in CKD. We do this by first explaining the excitation-contraction coupling, outlining current translational research approaches, then explaining the main characteristics in CKD patients, such as abnormalities in electrolytes and pH, activation of the autonomic nervous system, and the renin-angiotensin-aldosterone system, as well as current evidence for proarrhythmic properties of uremic toxins. Finally, we discuss the substance class of sodium-glucose co-transporter 2 inhibitors (SGLT2i) on their potential to modify cardiac channel regulation in CKD and, therefore, as a treatment option for arrhythmias.
    MeSH term(s) Humans ; Arrhythmias, Cardiac ; Renal Insufficiency ; Renal Insufficiency, Chronic/complications ; Death, Sudden, Cardiac ; Ion Channels ; Sodium-Glucose Transporter 2 Inhibitors ; Kidney
    Chemical Substances Ion Channels ; Sodium-Glucose Transporter 2 Inhibitors
    Language English
    Publishing date 2023-09-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241814198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Salt feedback on the renin-angiotensin-aldosterone system.

    Schweda, Frank

    Pflugers Archiv : European journal of physiology

    2015  Volume 467, Issue 3, Page(s) 565–576

    Abstract: The renin-angiotensin-aldosterone system (RAAS) is a central element in the control of the salt and water balance of the body and arterial blood pressure. The activity of the RAAS is controlled by the protease renin, which is released from renal ... ...

    Abstract The renin-angiotensin-aldosterone system (RAAS) is a central element in the control of the salt and water balance of the body and arterial blood pressure. The activity of the RAAS is controlled by the protease renin, which is released from renal juxtaglomerular epithelioid cells (JGE cells) into the circulation. Renin release is regulated by a complex interplay of several locally acting hormones or mechanisms and longer feedback loops one of which involves salt intake. Acute NaCl loads or longer lasting high salt intakes suppress plasma renin activity, whereas reductions in NaCl intake stimulate it. Because the activation of the RAAS conserves the salt content of the body, a classical feedback loop between salt intake/body salt content and renin is established. Despite of its important role for body fluid homeostasis, the precise signaling pathways connecting salt intake with the synthesis and release of renin are only incompletely understood. Four putative controllers of the salt-dependent regulation of the RAAS have been suggested: (1) the macula densa mechanism which adjusts renin release in response to changes in the renal tubular salt concentration; (2) salt-dependent changes in the arterial blood pressure; (3) circulating salt-dependent hormones, particularly the atrial natriuretic peptide (ANP); and (4) renal sympathetic nervous activity, which is regulated by extracellular volume and arterial blood pressure. In this review, the role of these known controllers of the RAAS will be discussed with special emphasis on their relative contributions to the salt-dependent regulation of the RAAS at different time frames.
    MeSH term(s) Aldosterone/metabolism ; Animals ; Feedback, Physiological ; Humans ; Kidney/innervation ; Kidney/metabolism ; Kidney/physiology ; Renin-Angiotensin System ; Sodium/metabolism
    Chemical Substances Aldosterone (4964P6T9RB) ; Sodium (9NEZ333N27)
    Language English
    Publishing date 2015-03
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 6380-0
    ISSN 1432-2013 ; 0031-6768
    ISSN (online) 1432-2013
    ISSN 0031-6768
    DOI 10.1007/s00424-014-1668-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.35: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Book ; Online ; Thesis: Anpassungsvorgänge des Nephrons an die Hemmung der Glukoseresorption durch SGLT2-Inhibitoren

    Schwarzfischer, Magdalena [Verfasser] / Schweda, Frank [Akademischer Betreuer]

    2023  

    Author's details Magdalena Schwarzfischer ; Betreuer: Frank Schweda
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language German
    Publisher Universitätsbibliothek Regensburg
    Publishing place Regensburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Book ; Online ; Thesis: Interstitielle reninbildende Zellen der murinen Niere

    Baier, Julius [Verfasser] / Schweda, Frank [Akademischer Betreuer]

    2023  

    Author's details Julius Baier ; Betreuer: Frank Schweda
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Regensburg
    Publishing place Regensburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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