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  1. AU="Sciacca, Chiara"
  2. AU=Magee L A
  3. AU="Mansour, Heba Mohamed"
  4. AU="Iglesias-Gutiérrez, Eduardo"
  5. AU="He, Yudou"
  6. AU="Dadas, Osman"
  7. AU="Chen, Fiona"
  8. AU=Itoh Nobuyuki
  9. AU="Adorjan, Kristina"
  10. AU="Humaid Al-Shamsi, Mohammed"
  11. AU="TATIANA B. FANTAZZINI"
  12. AU="Yonan, Charles"
  13. AU="Denic, Milica"
  14. AU="Pértega-Díaz, Sonia"
  15. AU=Passos Maria do Carmo Friche
  16. AU=Lumb Bridget M
  17. AU="Drabo, Emmanuel F"
  18. AU="Raux, M"
  19. AU="Kubba, Haytham"
  20. AU="Hence, Deanna"
  21. AU="Swiger, James"
  22. AU="Loftus Jr, E. V."
  23. AU="Pozzi Mucelli, Roberto"
  24. AU="Subedi, Prajan"
  25. AU=Xiao Xizhu
  26. AU="Franzén, Anna"
  27. AU=Klonoff David C
  28. AU="DeCobelli, Francesco"
  29. AU="Zhang, KaiDong"

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  1. Artikel ; Online: Long-term Inhibition of Soleus H-reflex with Epidural Adhesiolysis and Pulsed Radiofrequency in Lumbosacral Neuropathic Pain.

    Vigneri, Simone / Sindaco, Gianfranco / La Grua, Marco / Zanella, Matteo / Paci, Valentina / Vinci, Francesca Maria / Sciacca, Chiara / Merlini, Alberto / Pari, Gilberto

    Pain practice : the official journal of World Institute of Pain

    2020  Band 21, Heft 3, Seite(n) 277–284

    Abstract: Introduction: Scientific data about neurophysiological changes subsequent to pulsed radiofrequency (PRF) are still lacking. The goal of this study was to evaluate sural nerve conduction and Hoffmann reflex (H-reflex) in soleus muscle following ... ...

    Abstract Introduction: Scientific data about neurophysiological changes subsequent to pulsed radiofrequency (PRF) are still lacking. The goal of this study was to evaluate sural nerve conduction and Hoffmann reflex (H-reflex) in soleus muscle following adhesiolysis and PRF in patients with unilateral chronic lumbosacral L5-S1 neuropathic radiating pain.
    Methods: Seventeen patients received two cycles of 240 seconds high-voltage PRF and epidural adhesiolysis. Sural nerve action potential (SNAP) and the ratio of maximum H-reflex to maximum M response (H/M ratio) as well as pain scores were collected in both lower limbs before, immediately following, and 1 month after the treatment.
    Results: At follow-up, a significant reduction in numeric rating scale (NRS) and Douleur Neuropathique 4 Questions (DN4) scores was observed in 53% of patients reporting pain improvement of ≥ 30% over baseline. The H/M ratio was decreased in the affected limb following PRF (P = 0.01) and 1 month after the treatment (P = 0.04). A direct correlation was observed between H/M ratio variation and NRS score at follow-up in the treated limb (P = 0.04). No significant difference in sural nerve latency, amplitude, and velocity was detected between affected and normal side after treatment and at follow-up.
    Conclusions: Epidural adhesiolysis and PRF of the dorsal root ganglion seem to significantly affect spinal reflexes in patients with lumbosacral neuropathic radiating pain.
    Mesh-Begriff(e) Adult ; Aged ; Epidural Space ; Female ; Follow-Up Studies ; Ganglia, Spinal/physiopathology ; Ganglia, Spinal/radiation effects ; Humans ; Italy ; Lumbosacral Region ; Male ; Middle Aged ; Muscle, Skeletal/innervation ; Muscle, Skeletal/physiopathology ; Neural Inhibition/physiology ; Neuralgia/physiopathology ; Neuralgia/therapy ; Pain Management/methods ; Pulsed Radiofrequency Treatment/methods ; Reflex/physiology ; Tissue Adhesions/pathology ; Tissue Adhesions/therapy ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2020-10-25
    Erscheinungsland United States
    Dokumenttyp Clinical Trial ; Journal Article
    ZDB-ID 2151272-3
    ISSN 1533-2500 ; 1530-7085
    ISSN (online) 1533-2500
    ISSN 1530-7085
    DOI 10.1111/papr.12955
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain: A Randomized Controlled Study.

    Vigneri, Simone / Sindaco, Gianfranco / La Grua, Marco / Zanella, Matteo / Lo Bianco, Giuliano / Paci, Valentina / Vinci, Francesca M / Sciacca, Chiara / Ravaioli, Laura / Pari, Gilberto

    The Clinical journal of pain

    2019  Band 36, Heft 1, Seite(n) 25–33

    Abstract: Objectives: Despite the interest in scientific community, there is still poor evidence about pulsed radiofrequency (PRF) efficacy in the treatment of neuropathic pain. In order to determine whether high-voltage PRF and epidural adhesiolysis (PRF-EA) ... ...

    Abstract Objectives: Despite the interest in scientific community, there is still poor evidence about pulsed radiofrequency (PRF) efficacy in the treatment of neuropathic pain. In order to determine whether high-voltage PRF and epidural adhesiolysis (PRF-EA) showed better results than epidural adhesiolysis alone (EA), a randomized, double-blind, comparative-effectiveness study was conducted in patients with chronic lumbosacral radiating pain and neuropathic features.
    Materials and methods: A total of 41 patients were randomly allocated to 2 groups. Twenty-one patients were randomized to receive 2 cycles of 240 seconds high-voltage PRF followed by the injection of local anesthetics, hyaluronidase, and betamethasone, whereas 20 patients underwent sham stimulation followed by adhesiolysis. The treatment was delivered at the affected lumbosacral roots and patients, treating physicians and assessors were blinded to intervention.
    Results: A significant reduction of radiating pain was observed in mean Numeric Rating Scale score at follow-up. A change of -3.43 versus -1.75 (P=0.031) after 1 month and -3.34 versus -0.80 (P=0.005) after 6 months was reported in patients undergoing PRF-EA in comparison with EA, respectively. After 1 month, 57% of patients in the PRF-EA group experienced a pain reduction of ≥50% versus only 25% of patients allocated to EA (P=0.037). Improvement decreased to 48% in the PRF-EA group whereas only 10% of EA reported significant pain relief after 6 months (P=0.008).
    Discussion: High-voltage PRF of dorsal root ganglion delivered through multifunctional electrode provided significant pain relief and may be considered a valuable treatment in chronic lumbosacral radicular pain with neuropathic features.
    Mesh-Begriff(e) Ganglia, Spinal ; Humans ; Low Back Pain/therapy ; Neuralgia/therapy ; Pain Management ; Pulsed Radiofrequency Treatment ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2019-10-02
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Randomized Controlled Trial
    ZDB-ID 632582-8
    ISSN 1536-5409 ; 0749-8047
    ISSN (online) 1536-5409
    ISSN 0749-8047
    DOI 10.1097/AJP.0000000000000766
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 2078: Hefte anzeigen Standort:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

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