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  1. Article: Protein Loss Enteropathy as an Initial Presentation of Gastric Epstein-Barr Virus Lymphoma.

    Niazi, Bilal / Ali, Saad / Elias, Sameh / Sciarra, Michael

    Case reports in gastrointestinal medicine

    2022  Volume 2022, Page(s) 5143760

    Abstract: Protein loss enteropathy (PLE) is a complex disease process that can result in potentially fatal protein losses. Gastrointestinal protein losses usually arise from damage to the gastrointestinal mucosa or from lymphatic obstruction. The goal of ... ...

    Abstract Protein loss enteropathy (PLE) is a complex disease process that can result in potentially fatal protein losses. Gastrointestinal protein losses usually arise from damage to the gastrointestinal mucosa or from lymphatic obstruction. The goal of management is to identify and treat the underlying causes and maintain normal serum protein levels. Here, we present a patient with diarrhea and generalized edema, with decreased serum albumin and gamma-globulin levels, concerning for protein loss enteropathy. He was ultimately found to be positive for HIV infection, and his stool alpha-1 antitrypsin levels were diagnostic of protein loss enteropathy. His endoscopic and histologic evaluation revealed gastric Epstein-Barr virus-encoded small RNA- (EBER-) positive lymphoma. Though gastrointestinal lymphomas are known to cause PLE, this will be the first documented case of EBER-positive gastric lymphoma presenting with PLE. We hope to bring awareness to this unique presentation to aid in expedient diagnosis and treatment to avoid delays in treatment and potentially fatal outcomes.
    Language English
    Publishing date 2022-06-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627636-7
    ISSN 2090-6536 ; 2090-6528
    ISSN (online) 2090-6536
    ISSN 2090-6528
    DOI 10.1155/2022/5143760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Appendiceal Bulge on Routine Colonoscopy: Not All Disease Is Luminal.

    Taj, Sobaan / Akbar, Usman Ali / Philip, Shawn / Miller, Brett / Haq, ZakaUl / Sanekommu, Harshavardhan / Hossain, Mohammad A / Sciarra, Michael

    Cureus

    2023  Volume 15, Issue 2, Page(s) e35466

    Abstract: Appendiceal ... ...

    Abstract Appendiceal mucocele
    Language English
    Publishing date 2023-02-25
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.35466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Recent advances in endoscopy.

    Weissman, Simcha / Sciarra, Michael A / Al-Dulaimi, David

    Gastroenterology and hepatology from bed to bench

    2019  Volume 12, Issue 4, Page(s) 374–375

    Language English
    Publishing date 2019-10-22
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2569124-7
    ISSN 2008-4234 ; 2008-2258
    ISSN (online) 2008-4234
    ISSN 2008-2258
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  4. Article ; Online: Biliary Fibrosis and Portal Hypertension as a Rare Cause of Cholangiocarcinoma.

    Hassan, Ammar / Weissman, Simcha / Pinkhasov, Mark / Sciarra, Michael

    Journal of gastrointestinal cancer

    2019  Volume 51, Issue 2, Page(s) 647–648

    MeSH term(s) Aged ; Bile Duct Neoplasms/etiology ; Bile Duct Neoplasms/pathology ; Bile Ducts/pathology ; Cholangiocarcinoma/etiology ; Cholangiocarcinoma/pathology ; Female ; Fibrosis/complications ; Fibrosis/pathology ; Humans ; Hypertension, Portal/complications ; Hypertension, Portal/pathology ; Prognosis
    Language English
    Publishing date 2019-11-27
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2452514-5
    ISSN 1941-6636 ; 1559-0739 ; 1941-6628 ; 1537-3649
    ISSN (online) 1941-6636 ; 1559-0739
    ISSN 1941-6628 ; 1537-3649
    DOI 10.1007/s12029-019-00346-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2184: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: "HASH"ing out pancreatitis: the new increasingly common culprit.

    Chandy, Joel / Hassan, Ammar / Sciarra, Michael

    Journal of community hospital internal medicine perspectives

    2019  Volume 9, Issue 4, Page(s) 360–361

    Abstract: Acute pancreatitis is a serious, potentially life threatning inflammatory disorder of the pancreas usually caused by alcohol use or gallstones. Other causes include certain drugs (such as antibiotics, antihypertensive medications, and immunosuppressants) ...

    Abstract Acute pancreatitis is a serious, potentially life threatning inflammatory disorder of the pancreas usually caused by alcohol use or gallstones. Other causes include certain drugs (such as antibiotics, antihypertensive medications, and immunosuppressants) and extremley high triglyceride levels.Cannabis use has been identified as an uncommon cause of acute pancreatitis. However, due to its rarity in the general population, it has been low on practitioners' differential diagnosis. As a result, the incidence is likely underrepresented as these patients' recurrent episodes of pancreatitis are likely labeled as idiopathic when in fact they are not. This case report highlights the importance of keeping a wide differential when considering possible causes of pancreatitis.
    Language English
    Publishing date 2019-09-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2616884-4
    ISSN 2000-9666
    ISSN 2000-9666
    DOI 10.1080/20009666.2019.1624138
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  6. Article: Isolated Intestinal Angioedema Secondary to a Food Allergen.

    Hassan, Ammar / Weissman, Simcha / Sciarra, Michael A / Sotiriadis, John

    ACG case reports journal

    2019  Volume 6, Issue 9, Page(s) e00222

    Abstract: Intestinal angioedema is the dilatation or thickening, or both, of a segment of bowel. It is a diagnostic phenomenon that manifests itself clinically as acute abdominal pain, diarrhea, and emesis. Generally, this condition occurs in tandem with ... ...

    Abstract Intestinal angioedema is the dilatation or thickening, or both, of a segment of bowel. It is a diagnostic phenomenon that manifests itself clinically as acute abdominal pain, diarrhea, and emesis. Generally, this condition occurs in tandem with angioedema of the face and tongue and/or in association with the use of an angiotensin-converting enzyme inhibitor (ACE-I). We present a rare case of a 63-year-old woman who developed isolated intestinal angioedema due to the ingestion of a food allergen.
    Language English
    Publishing date 2019-09-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Acrodermatitis Enteropathica Associated With Inflammatory Bowel Disease.

    Weissman, Simcha / Aziz, Muhammad / Saleem, Saad / Hassan, Ammar / Sciarra, Michael

    ACG case reports journal

    2019  Volume 6, Issue 9, Page(s) e00209

    Language English
    Publishing date 2019-08-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Are Quality Metrics in Inflammatory Bowel Disease Rooted on Substantial Quality Evidence? A Systematic Review.

    Weissman, Simcha / Goldowsky, Alexander / Mehta, Tej I / Sciarra, Michael A / Feuerstein, Joseph D

    Journal of Crohn's & colitis

    2020  

    Abstract: Background and aims: Quality metrics were established to develop standards to help assess quality of care, yet variation in inflammatory bowel disease (IBD) clinical practice exists. We performed a systematic review to assess the overall quality of ... ...

    Abstract Background and aims: Quality metrics were established to develop standards to help assess quality of care, yet variation in inflammatory bowel disease (IBD) clinical practice exists. We performed a systematic review to assess the overall quality of evidence cited in formulating IBD quality metrics.
    Methods: A systematic search was performed on PubMed, MEDLINE, and EMBASE. All major national and international IBD societies were included. Quality metrics were assessed for evidence quality and categorized as category A (guideline based), category B (primarily retrospective and observational studies) or category C (expert opinion). Quality metrics were examined for the type of metric, the quality, measurability, review, existing conflicts of interest (COI), and patient participation of the metric. Statistical analysis was conducted in R.
    Results: A total of 143 distinct, and an aggregate total of 217 quality metrics were included and analyzed. 68%, 3.2%, and 28.6% of IBD quality metrics were based on low, moderate, and high quality of evidence, respectively. The proportion of high quality evidence across societies was significantly different (P <0.01). Five organizations included patients in quality metric development, three reported external review, not all reported measurable outcomes or stated the presence of a COI. Finally, 43% of quality metrics were published more than 5 years ago.
    Conclusions: Quality metrics are important to standardize practice. As more than two-thirds of the quality metrics in IBD are based on low quality evidence, further studies are needed to improve the overall quality of evidence supporting the development of quality measures.
    Language English
    Publishing date 2020-06-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2390120-2
    ISSN 1876-4479 ; 1873-9946
    ISSN (online) 1876-4479
    ISSN 1873-9946
    DOI 10.1093/ecco-jcc/jjaa123
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6634: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Increased Mortality and Healthcare Costs Upon Hospital Readmissions of Ulcerative Colitis Flares: A Large Population-Based Cohort Study.

    Weissman, Simcha / Sharma, Sachit / Fung, Brian M / Aziz, Muhammad / Sciarra, Michael / Swaminath, Arun / Feuerstein, Joseph D

    Crohn's & colitis 360

    2021  Volume 3, Issue 3, Page(s) otab029

    Abstract: Background: Ulcerative colitis (UC) flares often result in prolonged hospitalization and considerable mortality. Nevertheless, large-scale analyses evaluating the frequency and characteristics of hospital readmissions for UC remain limited. We aimed to ... ...

    Abstract Background: Ulcerative colitis (UC) flares often result in prolonged hospitalization and considerable mortality. Nevertheless, large-scale analyses evaluating the frequency and characteristics of hospital readmissions for UC remain limited. We aimed to examine these clinical outcomes in a nationwide cohort of patients hospitalized with UC.
    Methods: We queried the 2017 Nationwide Readmission Database using ICD-10-CM codes to identify all adult patients admitted for UC. Outcomes including mortality, readmission rates, predictors of readmission and mortality, and healthcare usage were assessed. Multivariate analysis was used to adjust for potential confounders.
    Results: From the 31,063 patients hospitalized for UC, 17.38% were readmitted within 30 days and 28.51% in 90 days. UC accounted for 28.17% and 29.82% of readmissions at 30 and 90 days, respectively. Compared to index admission, 30- and 90-day readmissions were characterized by significantly higher mortality (0.42% vs 1.99% and 1.65%, respectively), longer hospital stays (5.05 vs 6.62 and 6.04 days, respectively), and increased hospital cost ($49,999 vs $62,288 and $59,698, respectively) (all
    Conclusions: In a large cohort of patients hospitalized for UC, we found that readmission is associated with higher mortality and more lengthy/costly admissions. Additionally, we found independent associations for readmission and mortality that may help identify patients who can benefit from close postdischarge follow-up.
    Language English
    Publishing date 2021-06-09
    Publishing country England
    Document type Journal Article
    ISSN 2631-827X
    ISSN (online) 2631-827X
    DOI 10.1093/crocol/otab029
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  10. Article: Bile Cast Nephropathy an Important Biliary Culprit of Kidney Injury.

    Yusuf, Fouzia / Weissman, Simcha / Qureshi, Nabeel / Ibrahim, Mounir / Kurtz, Daniel / Manandhar, Lochana / Sciarra, Michael / Elias, Sameh

    Journal of community hospital internal medicine perspectives

    2021  Volume 11, Issue 2, Page(s) 253–255

    Abstract: Bile cast nephropathy (BCN) is a rare form of acute kidney injury (AKI) that occurs in the setting of hyperbilirubinemia. We present the case of a 67 year-old male with severe kidney injury who was found to have obstructive cholestasis. By way of this ... ...

    Abstract Bile cast nephropathy (BCN) is a rare form of acute kidney injury (AKI) that occurs in the setting of hyperbilirubinemia. We present the case of a 67 year-old male with severe kidney injury who was found to have obstructive cholestasis. By way of this report, we aim to expand upon the existing literature and showcase the importance of timely endoscopic retrograde cholangio-pancreatography (ERCP) in this setting, in order to prevent irreversible kidney damage.
    Language English
    Publishing date 2021-03-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2616884-4
    ISSN 2000-9666
    ISSN 2000-9666
    DOI 10.1080/20009666.2021.1877397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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