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  1. Article ; Online: Measurement inaccuracies in widefield imaging-a cautionary tale.

    Lucente, Amedeo / Taloni, Andrea / Scorcia, Vincenzo / Giannaccare, Giuseppe

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

    2024  Volume 262, Issue 4, Page(s) 1365–1367

    MeSH term(s) Humans ; Diagnostic Imaging
    Language English
    Publishing date 2024-01-04
    Publishing country Germany
    Document type Letter
    ZDB-ID 8435-9
    ISSN 1435-702X ; 0721-832X
    ISSN (online) 1435-702X
    ISSN 0721-832X
    DOI 10.1007/s00417-023-06356-y
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  2. Article ; Online: Longitudinal Observation of Two Giant Peripheral Atrophic Retinal Holes Left Untreated.

    Lucente, Amedeo / Taloni, Andrea / Scorcia, Vincenzo / Giannaccare, Giuseppe

    Ophthalmic surgery, lasers & imaging retina

    2024  Volume 55, Issue 3, Page(s) 176–178

    Abstract: In this report, two rare cases of large atrophic peripheral retinal holes are described. Both patients presented during a routine visit without reporting any ocular symptoms. The holes did not exhibit significant risk factors for progression to ... ...

    Abstract In this report, two rare cases of large atrophic peripheral retinal holes are described. Both patients presented during a routine visit without reporting any ocular symptoms. The holes did not exhibit significant risk factors for progression to rhegmatogenous retinal detachment: No signs of posterior vitreous detachment, vitreoretinal tractions, or retinal degeneration were visible. For such asymptomatic cases, international guidelines recommend a strict follow-up schedule; however, the unusual size of the holes raised significant concerns about the management of these retinal breaks. The advantages and disadvantages of laser photo-coagulation treatment were discussed, ultimately favoring a watch-and-wait strategy.
    MeSH term(s) Humans ; Retinal Perforations/diagnosis ; Retinal Perforations/etiology ; Retinal Perforations/surgery ; Retinal Detachment/surgery ; Vitreous Detachment ; Retinal Degeneration ; Laser Therapy
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2701167-7
    ISSN 2325-8179 ; 2325-8160
    ISSN (online) 2325-8179
    ISSN 2325-8160
    DOI 10.3928/23258160-20240105-01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Widefield and Ultra-Widefield Retinal Imaging: A Geometrical Analysis.

    Lucente, Amedeo / Taloni, Andrea / Scorcia, Vincenzo / Giannaccare, Giuseppe

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 1

    Abstract: Diabetic retinopathy (DR) often causes a wide range of lesions in the peripheral retina, which can be undetected when using a traditional fundus camera. Widefield (WF) and Ultra-Widefield (UWF) technologies aim to significantly expand the photographable ... ...

    Abstract Diabetic retinopathy (DR) often causes a wide range of lesions in the peripheral retina, which can be undetected when using a traditional fundus camera. Widefield (WF) and Ultra-Widefield (UWF) technologies aim to significantly expand the photographable retinal field. We conducted a geometrical analysis to assess the field of view (FOV) of WF and UWF imaging, comparing it to the angular extension of the retina. For this task, we shot WF images using the Zeiss Clarus 500 fundus camera (Carl Zeiss Meditec, Jena, Germany). Approximating the ocular bulb to an ideal sphere, the angular extension of the theoretically photographable retinal surface was 242 degrees. Performing one shot, centered on the macula, it was possible to photograph a retinal surface of ~570 mm
    Language English
    Publishing date 2023-01-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13010202
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  4. Article ; Online: Large Language Model Advanced Data Analysis Abuse to Create a Fake Data Set in Medical Research.

    Taloni, Andrea / Scorcia, Vincenzo / Giannaccare, Giuseppe

    JAMA ophthalmology

    2023  Volume 141, Issue 12, Page(s) 1174–1175

    MeSH term(s) Humans ; Biomedical Research ; Data Analysis
    Language English
    Publishing date 2023-11-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2023.5162
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  5. Article ; Online: Reply.

    Giannaccare, Giuseppe / Pellegrini, Marco / Scorcia, Vincenzo

    Cornea

    2023  Volume 42, Issue 10, Page(s) e19–e20

    Language English
    Publishing date 2023-07-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000003351
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  6. Article ; Online: Modern threats in academia: evaluating plagiarism and artificial intelligence detection scores of ChatGPT.

    Taloni, Andrea / Scorcia, Vincenzo / Giannaccare, Giuseppe

    Eye (London, England)

    2023  Volume 38, Issue 2, Page(s) 397–400

    MeSH term(s) Humans ; Plagiarism ; Academia ; Artificial Intelligence
    Language English
    Publishing date 2023-08-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-023-02678-7
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  7. Article ; Online: Phacoemulsification Under the Complex Dua Layer-Descemet-Endothelium for Combined Cataract Surgery and Penetrating Keratoplasty After Failed Deep Anterior Lamellar Keratoplasty.

    Lucisano, Andrea / Scorcia, Vincenzo / Rossi, Costanza / Scalia, Giovanni / Giannaccare, Giuseppe

    Cornea

    2023  Volume 42, Issue 10, Page(s) 1297–1300

    Abstract: Purpose: The aim of this study was to report the surgical management of an eye with a cataract and a failed deep anterior lamellar keratoplasty (DALK) graft. Given the null visualization of the anterior chamber, instead of performing penetrating ... ...

    Abstract Purpose: The aim of this study was to report the surgical management of an eye with a cataract and a failed deep anterior lamellar keratoplasty (DALK) graft. Given the null visualization of the anterior chamber, instead of performing penetrating keratoplasty (PK) combined with open-sky extracapsular extraction, the cleavage plane of the previous DALK was used to expose the transparent complex including Dua layer (DL)-Descemet membrane (DM)-endothelium and to perform phacoemulsification in a closed system; then, PK was completed after the surgical removal of the complex DL-DM-endothelium.
    Methods: This study is a case report.
    Results: A 45-year-old woman with corneal opacity due to Acanthamoeba keratitis underwent multiple (n = 2) DALK surgeries. The second DALK graft underwent failure, with the development of severe corneal edema; a dense opacity of the lens was also present. The patient was scheduled for combined PK and cataract surgery. Because the cornea was too opaque to allow closed-system cataract surgery, a partial trephination was performed with the purpose of reopening the old donor-host junction and finding the deep cleavage plane. This maneuver permitted the exposition of the complex DL-DM-endothelium that was completely transparent, thus allowing standard phacoemulsification using the phaco-chop technique. A full-thickness corneal graft was then positioned and sutured.
    Conclusions: This case confirms the toughness of the complex DL-DM-endothelium and reveals the transparency of this complex even in the presence of a failed endothelium, thus highlighting distinct advantages of our surgical approach over the conventional one involving PK combined with open-sky extracapsular extraction.
    MeSH term(s) Female ; Humans ; Middle Aged ; Keratoplasty, Penetrating/methods ; Phacoemulsification/methods ; Corneal Transplantation/methods ; Cataract ; Endothelium
    Language English
    Publishing date 2023-07-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000003338
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    Zs.A 1790: Show issues Location:
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  8. Article ; Online: Nationwide pharmacy-based dry eye disease screening: analysis of cross-sectional data from 8259 individuals.

    Pellegrini, Marco / Yu, Angeli Christy / Scorcia, Vincenzo / Giannaccare, Giuseppe

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

    2023  Volume 262, Issue 2, Page(s) 663–665

    MeSH term(s) Humans ; Cross-Sectional Studies ; Pharmacy
    Language English
    Publishing date 2023-07-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 8435-9
    ISSN 1435-702X ; 0721-832X
    ISSN (online) 1435-702X
    ISSN 0721-832X
    DOI 10.1007/s00417-023-06174-2
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  9. Article ; Online: Spontaneous intraocular lens extrusion through Gundersen conjunctival graft after multiple failed keratoplasties: A report of two cases.

    Giannaccare, Giuseppe / Nadeem, Sana / Vaccaro, Sabrina / Scorcia, Vincenzo

    European journal of ophthalmology

    2022  Volume 33, Issue 5, Page(s) NP79–NP82

    Abstract: Purpose: To report the occurrence and the outcomes of 2 cases of spontaneous extrusion of 3-piece intraocular lens (IOL) through a Gundersen conjunctival flap performed for tectonic purposes after multiple failed penetrating keratoplasties (PKs).: ... ...

    Abstract Purpose: To report the occurrence and the outcomes of 2 cases of spontaneous extrusion of 3-piece intraocular lens (IOL) through a Gundersen conjunctival flap performed for tectonic purposes after multiple failed penetrating keratoplasties (PKs).
    Methods: A 70-year-old woman (Patient #1) with severe dry eye disease who had undergone cataract surgery with posterior chamber 3-piece IOL implantation, multiple PKs and Gundersen conjunctival flap in her left eye presented with partial extrusion of the optic and the inferior haptic of the IOL through the conjunctival flap. Inferior symblepharon and keratinization of the entire ocular surface were also present. A 64-year-old diabetic man (Patient #2) with history of cataract surgery with a posterior chamber IOL implantation, multiple PKs for keratoconus and Gunderson conjunctival flap in his right eye presented with partial extrusion of IOL optic through the conjunctival flap.
    Results: Patient #1 refused a further surgery and IOL was removed at the slit lamp. Currently, 3 months after IOL extrusion, corneal perforation self-sealed, visual acuity of light perception is maintained, and the patient does not complain any symptoms of ocular discomfort or pain. In Patient #2, tectonic PK combined with IOL removal and anterior vitrectomy was performed. Currently, 1 month postoperatively corneal graft is clear, intraocular pressure is normal, and patient's vision is counting fingers.
    Conclusions: In both cases, IOL extrusion occurred spontaneously through a Gunderson conjunctival flap. Including the underlying Tenon's capsule in the conjunctival graft could increase its tectonic support, potentially avoiding this complication.
    MeSH term(s) Humans ; Male ; Female ; Aged ; Middle Aged ; Lens Implantation, Intraocular/adverse effects ; Lenses, Intraocular/adverse effects ; Corneal Transplantation ; Keratoconus/complications ; Cataract/complications ; Postoperative Complications
    Language English
    Publishing date 2022-10-27
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721221136433
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  10. Article: False Myths versus Medical Facts: Ten Common Misconceptions Related to Dry Eye Disease.

    Giannaccare, Giuseppe / Scorcia, Vincenzo

    Biomedicines

    2020  Volume 8, Issue 6

    Abstract: Since the first definition of dry eye, rapid progress has been made in this field over the past decades that has guided profound changes in the definition, classification, diagnosis and management of the disease. Although dry eye is one of the most ... ...

    Abstract Since the first definition of dry eye, rapid progress has been made in this field over the past decades that has guided profound changes in the definition, classification, diagnosis and management of the disease. Although dry eye is one of the most frequently encountered ocular conditions, various "old" misconceptions persist, in particular among comprehensive ophthalmologists not specialized in ocular surface diseases. These misconceptions hamper the correct diagnosis and the proper management of dry eye in the routine clinical practice. In the present review, we described the 10 most common misconceptions related to dry eye and provided an evidence-based guide for reconsidering them using the format "false myth versus medical fact". These misconceptions concern the dry eye definition and classification (#1, #2, #3), disease physiopathology (#4), diagnosis (#5), symptoms (#6, #7) and treatment (#8, #9, #10). Nowadays, dry eye is still an under-recognized and evolving disease that poses significant clinical challenges to ophthalmologists. The two major reasons behind these challenges include the heterogeneity of the conditions that fall under the umbrella term of dry eye and the common discrepancy between signs and symptoms.
    Language English
    Publishing date 2020-06-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines8060172
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