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  1. Book: Oxford textbook of rheumatoid arthritis

    Scott, David L. / Galloway, James B. / Cope, Andrew P.

    2020  

    Title variant Textbook of rheumatoid arthritis ; Rheumatoid arthritis
    Author's details edited by David L. Scott, James Galloway, Andrew Cope, Arthur G.Pratt, Vibeke Strand
    Keywords Rheumatoid arthritis
    Language English
    Size xiii, 556 Seiten, Illustrationen, 28 cm
    Publisher Oxford University Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT020580433
    ISBN 978-0-19-883143-3 ; 0-19-883143-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 A 1310 available for loan (reading room) Lesesaal EG

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  2. Book: Established rheumatoid arthritis

    Scott, David L.

    (Best practice & research : Clinical rheumatology ; 21,5)

    2007  

    Author's details David L. Scott ..., guest ed
    Series title Best practice & research : Clinical rheumatology ; 21,5
    Best practice & research
    Best practice & research ; Clinical rheumatology
    Collection Best practice & research
    Best practice & research ; Clinical rheumatology
    Language English
    Size S. 805 - 967 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015307523
    ISBN 978-0-7020-2956-1 ; 0-7020-2956-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 1036 -21,5- verfügbar in Königswinter Königswinter

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  3. Book: Inflammatory arthritis in clinical practice

    Scott, Ian C. / Galloway, James B. / Scott, David L.

    2015  

    Author's details Ian C. Scott ; James B. Galloway ; David L. Scott
    Keywords Arthritis, Rheumatoid / drug therapy ; Spondylarthritis / drug therapy ; Inflammation / drug therapy ; Antirheumatic Agents / therapeutic use ; Anti-Inflammatory Agents / therapeutic use ; Arthritis/Chemotherapy ; Arthritis
    Subject code 616.722061
    Language English
    Size XVIII, 214 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Springer
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT018615953
    ISBN 978-1-4471-6647-4 ; 9781447166481 ; 1-4471-6647-7 ; 1447166485
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 1579 available for loan (reading room) Lesesaal EG

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  4. Article ; Online: The Effect of Perfusate Temperature on Delayed Graft Function in Deceased Donor Renal Transplantation.

    Sweet, Ashley L / Connelly, Christopher R / Dewey, Elizabeth N / Scott, David L

    Progress in transplantation (Aliso Viejo, Calif.)

    2023  Volume 33, Issue 4, Page(s) 341–347

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Humans ; Kidney Transplantation/adverse effects ; Temperature ; Delayed Graft Function/etiology ; Retrospective Studies ; Organ Preservation/adverse effects ; Kidney ; Tissue Donors ; Graft Survival
    Language English
    Publishing date 2023-11-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2864264-8
    ISSN 2164-6708 ; 1526-9248
    ISSN (online) 2164-6708
    ISSN 1526-9248
    DOI 10.1177/15269248231212920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Heterogeneity of treatment responses in rheumatoid arthritis using group based trajectory models: secondary analysis of clinical trial data.

    Ibrahim, Fowzia / Scott, Ian C / Scott, David L / Ayis, Salma Ahmed

    BMC rheumatology

    2023  Volume 7, Issue 1, Page(s) 33

    Abstract: Background: Traditionally rheumatoid arthritis (RA) trials classify patients as responders and non-responders; they ignore the potential range of treatment responses. Group Based Trajectory Models (GBTMs) provide a more refined approach. They identify ... ...

    Abstract Background: Traditionally rheumatoid arthritis (RA) trials classify patients as responders and non-responders; they ignore the potential range of treatment responses. Group Based Trajectory Models (GBTMs) provide a more refined approach. They identify patient subgroups with similar outcome trajectories. We used GBTMs to classify patients into subgroups of varying responses and explore factors associated with different responses to intensive treatment in a secondary analysis of intensive treatment in the TITRATE clinical trial.
    Methods: The TITRATE trial enrolled 335 patients with RA: 168 patients were randomised to receive intensive management, which comprised monthly assessments including measures of the disease activity score for 28 joints (DAS28), treatment escalation when patients were not responding sufficiently and psychosocial support; 163 of these patients completed the trial. We applied GBTMs to monthly DAS28 scores over one year to these patients who had received intensive management. The control group had standard care and were assessed every 6 months; they had too few DAS28 scores for applying GBTMs.
    Results: GBTMs identified three distinct trajectories in the patients receiving intensive management: good (n = 40), moderate (n = 76) and poor (n = 47) responders. Baseline body mass index (BMI), disability, fatigue and depression levels were significantly different between trajectory groups. Few (10%) good responders were obese, compared to 38% of moderate, and 43% of poor responders (P = 0.002). Few (8%) good responders had depression, compared to 14% moderate responders, and 38% poor responders (P < 0.001). The key difference in treatments was using high-cost biologics, used in only 5% of good responders but 30% of moderate and 51% of poor responders (P < 0.001). Most good responders had endpoint remissions and low disability, pain, and fatigue scores; few poor responders achieved any favourable outcomes.
    Conclusion: GBTMs identified three trajectories of disease activity progression in patients receiving intensive management for moderately active RA. Baseline variables like obesity and depression predicted different treatment responses. Few good responders needed biologic drugs; they responded to conventional DMARDs alone. GBTMs have the potential to facilitate precision medicine enabling patient-oriented treatment strategies based on key characteristics.
    Registration: TITRATE Trial ISRCTN 70160382.
    Language English
    Publishing date 2023-09-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2918121-5
    ISSN 2520-1026 ; 2520-1026
    ISSN (online) 2520-1026
    ISSN 2520-1026
    DOI 10.1186/s41927-023-00348-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Inflammatory arthritis in clinical practice

    Scott, David L. / Kingsley, Gabrielle Helen

    2008  

    Author's details David L. Scott and Gabrielle H. Kingsley
    Keywords Arthritis, Rheumatoid / drug therapy ; Spondylarthritis / drug therapy ; Inflammation / drug therapy ; Antirheumatic Agents / therapeutic use ; Anti-Inflammatory Agents / therapeutic use
    Language English
    Size IX, 116 S. : Ill., graph. Darst., 21cm
    Publisher Springer
    Publishing place London
    Publishing country Great Britain
    Document type Book
    Note Includes index. - Originally published as Inflammatory arthritis. S.l.: Current Medicine Group, 2006. - Formerly CIP
    HBZ-ID HT017022729
    ISBN 978-1-84628-932-3 ; 1-84628-932-7 ; 9781846289330 ; 1846289335
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 4418 order for loan Magazin

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  7. Article ; Online: Thromboembolism and Janus Kinase Inhibitors.

    Ibrahim, Fowzia / Scott, David L

    Drug safety

    2020  Volume 43, Issue 9, Page(s) 831–833

    MeSH term(s) Azetidines ; Humans ; Janus Kinase Inhibitors ; Piperidines ; Purines ; Pyrazoles ; Pyrimidines ; Sulfonamides ; Thromboembolism ; World Health Organization
    Chemical Substances Azetidines ; Janus Kinase Inhibitors ; Piperidines ; Purines ; Pyrazoles ; Pyrimidines ; Sulfonamides ; tofacitinib (87LA6FU830) ; baricitinib (ISP4442I3Y)
    Language English
    Publishing date 2020-07-17
    Publishing country New Zealand
    Document type Journal Article ; Comment
    ZDB-ID 1018059-x
    ISSN 1179-1942 ; 0114-5916
    ISSN (online) 1179-1942
    ISSN 0114-5916
    DOI 10.1007/s40264-020-00973-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 2127: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Book ; Online: Inflammatory Arthritis in Clinical Practice

    Scott, David L. / Kingsley, Gabrielle H.

    2007  

    Author's details by David L. Scott, Gabrielle H. Kingsley
    Keywords Emergency medicine ; Nursing ; Occupational Therapy ; Rehabilitation ; Rheumatology
    Language English
    Publisher Springer-Verlag London Limited
    Publishing place London
    Document type Book ; Online
    HBZ-ID TT050387273
    ISBN 978-1-8462-8932-3 ; 978-1-8462-8933-0 ; 1-8462-8932-7 ; 1-8462-8933-5
    DOI 10.1007/978-1-84628-933-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  9. Article: Developing new therapeutic approaches for rheumatoid arthritis: the continuing challenges of clinical assessments.

    Scott, David L

    F1000Research

    2016  Volume 5

    Abstract: The management of rheumatoid arthritis has changed dramatically over the last three decades. Improvements in clinical assessment have been a key driver of these changes. However, in the last five years, three areas of unresolved uncertainty have ... ...

    Abstract The management of rheumatoid arthritis has changed dramatically over the last three decades. Improvements in clinical assessment have been a key driver of these changes. However, in the last five years, three areas of unresolved uncertainty have dominated specialist thinking in the field. These challenges comprise identifying the optimal management target, determining how best to reach this target by using intensive treatments, and individualising management because not all patients need or respond to identical treatments. The key problem that links each of these areas is balancing different types of evidence and is most readily appreciated in relation to treatment intensity. Giving more intensive therapy improves outcomes but also increases risks and, with biologic treatments, substantially increases drug costs. Specialists and healthcare funders need to agree on how best to rationalise optimal care for patients with what is most effective and safe and what is affordable.
    Language English
    Publishing date 2016
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2699932-8
    ISSN 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.8812.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Beyond methotrexate monotherapy for early rheumatoid arthritis.

    Scott, David L

    Lancet (London, England)

    2016  Volume 388, Issue 10042, Page(s) 309–310

    MeSH term(s) Antibodies, Monoclonal, Humanized/therapeutic use ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Female ; Humans ; Male ; Methotrexate/therapeutic use
    Chemical Substances Antibodies, Monoclonal, Humanized ; Antirheumatic Agents ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2016-07-23
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(16)30678-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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