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  1. Book ; Thesis: Retinale Gefäßveränderungen als Surrogatmarker des primären Offenwinkelglaukoms

    Bölefahr, Sebastian David

    ein Pilotversuch zur Untersuchung des Streuungsverhaltens retinaler Gefäße mittels Spectral-Domain-OCT unter Einbindung und Evaluierung eines Algorithmus zur Detektion retinaler Gefäße in der konfokalen Laser-Scanning-Ophthalmoskopie

    2017  

    Author's details vorgelegt von Sebastian David Bölefahr
    Language German
    Size 89 Blatt, Illustrationen, Diagramme, 30 cm
    Publishing place Hamburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Hamburg, 2017
    Note Text deutsch, Zusammenfassung in deutscher und englischer Sprache ; Literaturverzeichnis: Blatt 73-80
    HBZ-ID HT020488443
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 E 999 order for loan Magazin

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  2. Book ; Online: Catalysis for Low Temperature Fuel Cells

    Sebastián, David / Baglio, Vincenzo

    2018  

    Abstract: Today, the development of active and stable catalysts still represents a challenge to overcome in the research field of low temperature fuel cells. Operation at low temperatures demands the utilization of highly active catalysts to reduce the activation ... ...

    Abstract Today, the development of active and stable catalysts still represents a challenge to overcome in the research field of low temperature fuel cells. Operation at low temperatures demands the utilization of highly active catalysts to reduce the activation energy of the electrochemical reactions involved at the electrodes, and thus obtain practical performances and high efficiencies. At present, the most practical catalysts in low temperature fuel cells are highly dispersed Pt nanoparticles. However, these present several drawbacks such as high cost, limited earth resources, sensitivity to contaminants, low tolerance to the presence of alcohols and stability due to carbon support corrosion and Pt dissolution. In the search for alternative catalysts, researchers have looked at several strategies: increase of the utilization of Pt catalysts by means of novel structures (metal/support), alloying with non-platinum metals, new carbon and non-carbon supports, cheaper platinum-group-metals like Pd, non-platinum-group metals catalysts (Fe-N-C, Co-N-C, etc.), etc. This book is intended to cover the most recent progresses in advanced electro-catalysts from the synthesis and characterization to the evaluation of performance and degradation mechanisms, in order to gain insights towards the development of highly active fuel cells
    Keywords Chemistry
    Size 1 electronic resource (210 p.)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020096976
    ISBN 9783038426585 ; 9783038426592 ; 303842658X ; 3038426598
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Age-related muscle atrophy? Mitofusin 2 the rescue.

    Creus, Agustina / Sebastián, David

    Acta physiologica (Oxford, England)

    2024  Volume 240, Issue 5, Page(s) e14135

    Language English
    Publishing date 2024-03-11
    Publishing country England
    Document type Editorial
    ZDB-ID 2218636-0
    ISSN 1748-1716 ; 1748-1708
    ISSN (online) 1748-1716
    ISSN 1748-1708
    DOI 10.1111/apha.14135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs 229: Show issues Location:
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  4. Book ; Thesis: Einfluss der totalen versus subtotalen laparoskopischen Hysterektomie auf die weibliche Sexualität unter Berücksichtigung der Erwartungshaltung

    Kircher, Anna-Theresa / Berlit, Sebastian

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Anna Theresa Kircher ; Referent: Herr Prof. (apl) Dr. med. Sebastian Berlit
    Language German
    Size 64 Blätter, Diagramme, Illustrationen
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2022
    HBZ-ID HT030008036
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 E 696 order for loan Magazin

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  5. Book ; Thesis: Partielle Defienz des Thyroxin-bindenden Globulins verursacht durch eine Mutation im Signalpeptid

    Knüdeler, Sebastian

    2011  

    Author's details vorgelegt von Sebastian David Knüdeler
    Language German
    Size 88 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Duisburg, Essen, Univ., Diss., 2012
    HBZ-ID HT017332365
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 E 1970 order for loan Magazin

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  6. Article ; Online: Mitochondrial fitness sustains healthy muscle aging.

    Irazoki, Andrea / Zorzano, Antonio / Sebastián, David

    Aging

    2023  Volume 15, Issue 13, Page(s) 5956–5958

    MeSH term(s) Humans ; Mitochondria/pathology ; Muscles ; Muscle, Skeletal/metabolism ; Sarcopenia/metabolism ; Mitochondrial Dynamics
    Language English
    Publishing date 2023-06-24
    Publishing country United States
    Document type Editorial
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.204857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Carbonized Polydopamine-Based Nanocomposites: The Effect of Transition Metals on the Oxygen Electrocatalytic Activity.

    Cebollada, Jesús / Sebastián, David / Lázaro, María Jesús / Martínez-Huerta, Maria Victoria

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 9

    Abstract: The electrochemical oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are the most critical processes in renewable energy-related technologies, such as fuel cells, water electrolyzers, and unitized regenerative fuel cells. N-doped ... ...

    Abstract The electrochemical oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are the most critical processes in renewable energy-related technologies, such as fuel cells, water electrolyzers, and unitized regenerative fuel cells. N-doped carbon composites have been demonstrated to be promising ORR/OER catalyst candidates because of their excellent electrical properties, tunable pore structure, and environmental compatibility. In this study, we prepared porous N-doped carbon nanocomposites (NC) by combining mussel-inspired polydopamine (PDA) chemistry and transition metals using a solvothermal carbonization strategy. The complexation between dopamine catechol groups and transition metal ions (Fe, Ni, Co, Zn, Mn, Cu, and Ti) results in hybrid structures with embedded metal nanoparticles converted to metal-NC composites after the carbonization process. The influence of the transition metals on the structural, morphological, and electrochemical properties was analyzed in detail. Among them, Cu, Co, Mn, and Fe N-doped carbon nanocomposites exhibit efficient catalytic activity and excellent stability toward ORR. This method improves the homogeneous distribution of the catalytically active sites. The metal nanoparticles in reduced (MnO, Fe
    Language English
    Publishing date 2023-05-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13091549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Self-Eating for Muscle Fitness: Autophagy in the Control of Energy Metabolism.

    Sebastián, David / Zorzano, Antonio

    Developmental cell

    2020  Volume 54, Issue 2, Page(s) 268–281

    Abstract: Cellular processes that sense and transmit metabolic changes are crucial for adaptation to external signals. In this regard, autophagy provides energy upon nutrient deprivation and represents a quality control mechanism that eliminates damaged organelles ...

    Abstract Cellular processes that sense and transmit metabolic changes are crucial for adaptation to external signals. In this regard, autophagy provides energy upon nutrient deprivation and represents a quality control mechanism that eliminates damaged organelles or proteins. Here, we review recent findings on the metabolic pathways controlling autophagy in skeletal muscle, a plastic tissue that undergoes major changes in energy demands. We also analyze the implications of autophagy in the regulation of energy metabolism in muscle and how alterations in this process affect energy homeostasis at the whole-body level and the development of metabolic diseases and aging.
    MeSH term(s) Adaptation, Physiological/physiology ; Animals ; Autophagy/physiology ; Energy Metabolism/physiology ; Homeostasis/physiology ; Humans ; Muscle, Skeletal/metabolism ; Organelles/metabolism
    Language English
    Publishing date 2020-07-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2054967-2
    ISSN 1878-1551 ; 1534-5807
    ISSN (online) 1878-1551
    ISSN 1534-5807
    DOI 10.1016/j.devcel.2020.06.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5742: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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    Zs.MG 76: Show issues

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  9. Article: Tailored Porous Carbon Xerogels for Fe-N-C Catalysts in Proton Exchange Membrane Fuel Cells.

    Álvarez-Manuel, Laura / Alegre, Cinthia / Sebastián, David / Napal, Pedro F / Lázaro, María Jesús

    Nanomaterials (Basel, Switzerland)

    2023  Volume 14, Issue 1

    Abstract: Atomically dispersed Fe-N-C catalysts for the oxygen reduction reaction (ORR) have been synthesized with a template-free method using carbon xerogels (CXG) as a porous matrix. The porosity of the CXGs is easily tunable through slight variations in the ... ...

    Abstract Atomically dispersed Fe-N-C catalysts for the oxygen reduction reaction (ORR) have been synthesized with a template-free method using carbon xerogels (CXG) as a porous matrix. The porosity of the CXGs is easily tunable through slight variations in the synthesis procedure. In this work, CXGs are prepared by formaldehyde and resorcinol polymerization, modifying the pH during the process. Materials with a broad range of porous structures are obtained: from non-porous to micro-/meso-/macroporous materials. The porous properties of CXG have a direct effect on Fe-N-CXG activity against ORR in an acidic medium (0.5 M H
    Language English
    Publishing date 2023-12-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano14010014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Transformation of CoFe2O4 spinel structure into active and robust CoFe alloy/N-doped carbon electrocatalyst for oxygen evolution reaction

    Gebreslase, Gebrehiwet Abrham / Martínez-Huerta, María Victoria / Sebastián, David / Lázaro, María Jesús

    Journal of colloid and interface science. 2022 Nov., v. 625

    2022  

    Abstract: Electrochemical water splitting is an environmentally benign technology employed for H₂ production; however, it is critically hampered by the sluggish kinetics of the oxygen evolution reaction (OER) at the positive electrode. In this work, nitrogen-doped ...

    Abstract Electrochemical water splitting is an environmentally benign technology employed for H₂ production; however, it is critically hampered by the sluggish kinetics of the oxygen evolution reaction (OER) at the positive electrode. In this work, nitrogen-doped carbon-coated CoFe electrocatalysts were synthesized via a three-step route comprising (1) hydrothermal reaction, (2) in-situ polymerization of dopamine and (3) carbonization. The effect of carbonized polydopamine on the overall physicochemical properties and electrochemical activity of CoFe catalysts was systematically studied. By controlling and optimizing the ratio of CoFe₂O₄ and dopamine contents, a transformation of the CoFe₂O₄ structure to CoFe alloy was observed. It was found that CoFe/NC₃₀% (prepared with 30% dopamine) exhibits an excellent catalytic activity towards OER. A small overpotential of 340 mV was required to generate a current density of 10 mA cm⁻² in a 1.0 M KOH electrolyte. More importantly, the CoFe/NC₃₀% catalyst reflected exceptional durability for at least 24 h. This research sheds light on the development of affordable, highly efficient, and durable electrocatalysts for OER.
    Keywords alloys ; carbon ; carbonization ; catalysts ; catalytic activity ; dopamine ; durability ; electrochemistry ; electrodes ; electrolytes ; oxygen production ; polymerization
    Language English
    Dates of publication 2022-11
    Size p. 70-82.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.06.005
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 71/707: Show issues

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