LIVIVO - Search results -

Search results

Result 1 - 8 of total 8

Search options

Article: Study of CD4+ T-lymphocytes in chronic kidney disease patients with COVID-19 infection.

Aziz, Shereen P / Abbas, Amany / Sayed, Sherif A / Mohamed, Tamer / Mohy, Osama / Sedky, Ahmed

The Egyptian journal of immunology

2024 Volume 31, Issue 1, Page(s) 155–161

Abstract: Chronic kidney disease (CKD) is a functional and/or structural kidney damage that lasts more than three months duration. This study aimed to analyze CD4+ T-lymphocytes levels in chronic CKD patients specifically, during the coronavirus disease 2019 ( ... ...

Abstract	Chronic kidney disease (CKD) is a functional and/or structural kidney damage that lasts more than three months duration. This study aimed to analyze CD4+ T-lymphocytes levels in chronic CKD patients specifically, during the coronavirus disease 2019 (COVID-19) pandemic to assess the adaptive cell-mediated immunity. The study measured absolute CD4+ T-lymphocytes counts by flowcytometry among participating individuals. The study included 146 subjects, 40 CKD patients and tested positive for COVID-19, 44 CKD patients and tested negative for COVID-19 and 62 normal individuals as controls. There was a significant impact of COVID-19 infection in CKD patients showing lower absolute CD4+ T-lymphocytes values to more than six folds compared to the control individuals (Odds Ratio: 72.63, p= 0.0001). Also, there was a significant correlation between the decrease in absolute CD4+ T-lymphocytes counts and the advanced stages of CKD. Therefore, the study indicated that CKD causes an obvious alteration in the body immune system as decreased CD4+ T-lymphocytes levels alongside with the advanced CKD stages. While COVID-19 infection exposes CKD patients to be 50% more likely to express lower values of CD4+ T-lymphocytes levels compared to the negative tested CKD patients. In conclusion, poor immune response and increased morbidity and mortality could be correlated with CKD patients especially when associated with COVID-19 infection as comorbidity.
MeSH term(s)	Humans ; COVID-19 ; CD4-Positive T-Lymphocytes ; Renal Insufficiency, Chronic/complications ; CD8-Positive T-Lymphocytes
Language	English
Publishing date	2024-01-15
Publishing country	Egypt
Document type	Journal Article
ISSN	1110-4902
ISSN	1110-4902
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Desnutrin as a Biomarker for Insulin Resistance in Patients with Vitiligo Vulgaris.

El-Hamd, Mohammed Abu / Sedky, Ahmed / Mahmoud, Asmaa B / Abd El-Magid, Wafaa M

Indian journal of dermatology

2023 Volume 68, Issue 4, Page(s) 366–371

Abstract: Background: Vitiligo is a common depigmented skin disorder characterised by the selective destruction of melanocytes.: Aims and objectives: This study aimed to assess serum desnutrin and its association with insulin resistance in patients with ... ...

Abstract	Background: Vitiligo is a common depigmented skin disorder characterised by the selective destruction of melanocytes. Aims and objectives: This study aimed to assess serum desnutrin and its association with insulin resistance in patients with vitiligo vulgaris. Materials and methods: This study was a cross-sectional case-control study. It included 45 patients with vitiligo vulgaris and 45 age- and sex-matched healthy controls. Patients were subjected to complete general and cutaneous evaluations. All participants were subjected to the assay of fasting blood glucose (FBG), cholesterol, triglyceride, high-density lipoprotein (HDL), very low-density lipoprotein (VLDL), low-density lipoprotein (LDL), fasting serum insulin and serum desnutrin. Homeostasis Model Assessment + insulin resistance (HOMA + IR) was calculated for all participants. Results: There were statistically significant differences between the patients with vitiligo vulgaris and healthy controls regarding HDL, FBG, fasting insulin, HOMA-IR, and serum desnutrin ( Conclusion: This study concluded that in patients with vitiligo vulgaris, as a result of increased serum levels of glucose and insulin, the serum desnutrin was suppressed, perhaps contributing to hyperlipidaemia and IR. So, low serum desnutrin could be a biomarker for IR in patients with vitiligo vulgaris. A multidisciplinary approach is essential for the early detection of diabetes mellitus, IR and hyperlipidemia among patients with vitiligo vulgaris to avoid cardiovascular and metabolic complications.
Language	English
Publishing date	2023-10-09
Publishing country	India
Document type	Journal Article
ZDB-ID	416069-1
ISSN	1998-3611 ; 0019-5154
ISSN (online)	1998-3611
ISSN	0019-5154
DOI	10.4103/ijd.ijd_435_22
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 817: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Exists a role for serum irisin in Egyptian Behcet’s patients with subclinical atherosclerosis?

Ismail, Mohamed A. / Mounir, Ola / Sedky, Ahmed / Algahlan, Hisham A. / Abda, Esam A. / Radwan, Ahmed R. / Abozaid, Hanan Sayed

Clin Rheumatol. 2023 Jan., v. 42, no. 1, p. 179-186

2023 , Page(s) 179–186

Abstract: OBJECTIVES: To examine the serum irisin level in a group of Behcet’s disease patients, its association with illness parameters, and its utility in diagnosing subclinical atherosclerosis. METHODS: This randomized case–control study included 50 patients ... ...

Abstract	OBJECTIVES: To examine the serum irisin level in a group of Behcet’s disease patients, its association with illness parameters, and its utility in diagnosing subclinical atherosclerosis. METHODS: This randomized case–control study included 50 patients and 50 age- and sex-matched controls. Carotid Doppler ultrasound for the measurement of the carotid artery intima-media thickness (CIMT) and ankle-brachial pressure index (ABPI) were performed. A clinical evaluation, lipogram, and serum irisin were also performed. RESULTS: Between the patients and the control group, there was a significant difference in CIMT, S. irisin level, and ankle-brachial pressure index; however, gender and BMI did not significantly affect CIMT, ABPI, or S. irisin level. CIMT demonstrated a substantial negative correlation with both S. irisin and ABPI (r = − 0.62, P 0.0001). With a sensitivity of up to 94.30% and a specificity of 93.30%, the ROC analysis revealed that a decrease in S. irisin level in Behcet’s patients was indicative of subclinical atherosclerosis. The drop in the ABPI level demonstrated a sensitivity of up to 94.30% and a specificity of 100%. CONCLUSION: Subclinical atherosclerosis is prevalent among Egyptian Behcet’s patients, and S. irisin can be employed as a biomarker for diagnosing subclinical atherosclerosis in Behcet’s illness.
Keywords	atherosclerosis ; biomarkers ; blood serum ; carotid arteries ; case-control studies ; clinical examination ; gender ; ultrasonography
Language	English
Dates of publication	2023-01
Size	p. 179-186
Publishing place	Springer International Publishing
Document type	Article ; Online
ZDB-ID	604755-5
ISSN	0770-3198
ISSN	0770-3198
DOI	10.1007/s10067-022-06368-9
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1740: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Soluble CD163 for Prediction of High-Risk Esophageal Varices and Variceal Hemorrhage in Patients with Liver Cirrhosis.

Taher, Mohamed Yousri / El-Hadidi, Abeer / El-Shendidi, Assem / Sedky, Ahmed

GE Portuguese journal of gastroenterology

2021 Volume 29, Issue 2, Page(s) 82–95

Abstract: Introduction: Activation of hepatic macrophages in liver disease is pathogenically related to portal hypertension (PH). Soluble CD163 (sCD163) is shed in blood by activated macrophages and may predict PH progression noninvasively. This study was ... ...

Abstract	Introduction: Activation of hepatic macrophages in liver disease is pathogenically related to portal hypertension (PH). Soluble CD163 (sCD163) is shed in blood by activated macrophages and may predict PH progression noninvasively. This study was designed to investigate the relation of serum sCD163 to the grade and bleeding risk of esophageal varices (EV) and its role for prediction of variceal hemorrhage (VH). Methods: The study included cirrhotic patients divided into 3 groups: patients who presented with acute upper gastrointestinal bleeding (UGIB) proved to originate from EV on endoscopy, patients without any history of UGIB but who revealed EV on surveillance endoscopy, and patients without endoscopic evidence of varices. Variceal grade and risk signs and bleeding stigmata were noted simultaneously with measurement of serum sCD163 concentration. Results: Serum sCD163 concentration showed a significant increase in cirrhotic patients compared to healthy subjects ( Conclusions: Serum sCD163 levels accurately predicted high-grade and high-risk EV and could help plan for primary prophylaxis. However, it modestly identified VH occurrence, and endoscopy would be required to make a definitive diagnosis.
Language	English
Publishing date	2021-07-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2835774-7
ISSN	2387-1954 ; 2341-4545
ISSN (online)	2387-1954
ISSN	2341-4545
DOI	10.1159/000516913
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Exists a role for serum irisin in Egyptian Behcet's patients with subclinical atherosclerosis?

Ismail, Mohamed A / Mounir, Ola / Sedky, Ahmed / Algahlan, Hisham A / Abda, Esam A / Radwan, Ahmed R / Abozaid, Hanan Sayed

Clinical rheumatology

2022 Volume 42, Issue 1, Page(s) 179–186

Abstract: Objectives: To examine the serum irisin level in a group of Behcet's disease patients, its association with illness parameters, and its utility in diagnosing subclinical atherosclerosis.: Methods: This randomized case-control study included 50 ... ...

Abstract	Objectives: To examine the serum irisin level in a group of Behcet's disease patients, its association with illness parameters, and its utility in diagnosing subclinical atherosclerosis. Methods: This randomized case-control study included 50 patients and 50 age- and sex-matched controls. Carotid Doppler ultrasound for the measurement of the carotid artery intima-media thickness (CIMT) and ankle-brachial pressure index (ABPI) were performed. A clinical evaluation, lipogram, and serum irisin were also performed. Results: Between the patients and the control group, there was a significant difference in CIMT, S. irisin level, and ankle-brachial pressure index; however, gender and BMI did not significantly affect CIMT, ABPI, or S. irisin level. CIMT demonstrated a substantial negative correlation with both S. irisin and ABPI (r = - 0.62, P 0.0001). With a sensitivity of up to 94.30% and a specificity of 93.30%, the ROC analysis revealed that a decrease in S. irisin level in Behcet's patients was indicative of subclinical atherosclerosis. The drop in the ABPI level demonstrated a sensitivity of up to 94.30% and a specificity of 100%. Conclusion: Subclinical atherosclerosis is prevalent among Egyptian Behcet's patients, and S. irisin can be employed as a biomarker for diagnosing subclinical atherosclerosis in Behcet's illness. Key Points • Serum irisin has been studied in numerous autoimmune disorders as a marker for subclinical atherosclerosis, although its importance in Behcet's disease remains unclear (BD). • We examined the change in serum irisin levels in Behcet's disease patients and healthy controls. In addition, its association with carotid artery intima-media thickness (CIMT) and ankle-brachial pressure index was investigated (ABPI). • Changes in serum irisin levels are significant in BD, and a decrease in irisin level indicates subclinical atherosclerosis.
MeSH term(s)	Humans ; Behcet Syndrome/diagnostic imaging ; Fibronectins ; Carotid Intima-Media Thickness ; Case-Control Studies ; Egypt ; Atherosclerosis/diagnostic imaging
Chemical Substances	Fibronectins
Language	English
Publishing date	2022-09-16
Publishing country	Germany
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	604755-5
ISSN	1434-9949 ; 0770-3198
ISSN (online)	1434-9949
ISSN	0770-3198
DOI	10.1007/s10067-022-06368-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1740: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Book ; Online: Living with heritage in Cairo

Sedky, Ahmed

area conservation in the Arab-Islamic city

2009

Abstract: The Arab-Islamic city has been always a glamorous urban dream in human cultural memory. This is manifested in Cairo, the world's largest medieval urban system where traditional lifestyles are still implemented. Nevertheless, despite the extensive efforts ...

Institution	ebrary, Inc
Author's details	Ahmed Sedky
Abstract	The Arab-Islamic city has been always a glamorous urban dream in human cultural memory. This is manifested in Cairo, the world's largest medieval urban system where traditional lifestyles are still implemented. Nevertheless, despite the extensive efforts to preserve Historic Cairo, it is sadly vulnerable.Ahmed Sedky investigates the reasons behind this condition, exploring and comparing regional and international case studies. Questions such as how and what to conserve are raised and elaborated through the perspectives of different stakeholders.A resulting evaluative framework is accumulated t
Keywords	Historic buildings ; Islamic architecture
Language	English
Size	Online-Ressource (xxii, 305 p), ill., maps
Publisher	American University in Cairo Press
Publishing place	Cairo
Document type	Book ; Online
Note	Includes bibliographical references (p. 265-287) and index
ISBN	9774162455 ; 9781936190638 ; 9789774162459 ; 193619063X
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Cap-preserving SMILE Enhancement Surgery.

Sedky, Ahmed N / Wahba, Sherine S / Roshdy, Maged M / Ayaad, Nermeen R

BMC ophthalmology

2018 Volume 18, Issue 1, Page(s) 49

Abstract: Background: Different enhancement procedures have been suggested for reduction of residual refractive errors after SMILE. The aim of this study is to evaluate an improved cap-preserving technique for enhancement after SMILE (Re-SMILE).: Methods: A ... ...

Abstract	Background: Different enhancement procedures have been suggested for reduction of residual refractive errors after SMILE. The aim of this study is to evaluate an improved cap-preserving technique for enhancement after SMILE (Re-SMILE). Methods: A retrospective case series was conducted at Eye subspecialty center, Cairo, Egypt on 9 eyes with myopia or myopic astigmatism (spherical equivalent - 8.0 and - 12.0D). undergoing SMILE procedure and needed second interference. This was either because the more myopic meridian was more than - 10.0 D and therefore planned to have two-steps procedure (six eyes) or because of under correction needing enhancement (three eyes). Assessment after the primary SMILE procedure was conducted at 1 day, 1 week, 1 month and 3 months postoperatively. Assessment after Re-SMILE was conducted at 1 day, 1 week, 1 month, 3 months, 6 months and 1 year postoperatively. The assessments included full ophthalmic examination, objective and subjective refraction, and rotating Scheimpflug camera imaging. Results: Preoperatively, the mean refractive spherical equivalent (MRSE) values were: - 9.36 ± 0. 89. After primary SMILE it was - 2.18 ± 0.71. After Re-SMILE it was - 0.13 ± 0.68. MRSE was significantly improved after both procedures (P < 0.01). The safety index of primary SMILE cases was 1.65 ± 0.62 and for Re-SMILE 1.13 ± 0.34 and the efficacy index was 1.14 ± 0.24 after primary SMILE and 1.11 ± 0.26 after Re-SMILE. Conclusion: Centered cap-preserving Re-SMILE is an effective procedure in reducing residual refractive errors after primary SMILE in high myopes.
MeSH term(s)	Adult ; Astigmatism/surgery ; Cornea/surgery ; Corneal Surgery, Laser/methods ; Female ; Humans ; Lasers, Excimer/therapeutic use ; Male ; Myopia/surgery ; Refraction, Ocular ; Refractive Surgical Procedures/methods ; Retrospective Studies ; Visual Acuity ; Young Adult
Language	English
Publishing date	2018-02-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2050436-6
ISSN	1471-2415 ; 1471-2415
ISSN (online)	1471-2415
ISSN	1471-2415
DOI	10.1186/s12886-018-0712-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Possible role of interleukin 21 and interleukin 33 in patients with genital warts.

Abu El-Hamd, Mohammed / Assaf, Hanan Abdel Rady / Sedky, Ahmed / Mohammad, Shrouk Haggag

Dermatologic therapy

2019 Volume 32, Issue 5, Page(s) e13063

Abstract: Genital warts (GWs) are most prevalent sexually transmitted infections, presenting especially among the sexually active young population of both sexes. Efficient cell-mediated immunity is needed for regression of GWs. To clarify the reactivity of ... ...

Abstract	Genital warts (GWs) are most prevalent sexually transmitted infections, presenting especially among the sexually active young population of both sexes. Efficient cell-mediated immunity is needed for regression of GWs. To clarify the reactivity of cellular immunity among patients with GWs by means of measurements of their levels of serum interleukin (IL)-21 and IL-33, hence, to identify the possible role of IL-21 and IL-33 in GWs, this study aimed to evaluate serum levels of IL-21 and IL-33 among patients with GWs in comparison with the results of the controls. Levels of serum IL-21 and IL-33 were assayed utilizing commercially enzyme-linked immune-sorbent assay kits in 45 patients with GWs and 45 healthy control subjects. Levels of serum IL-21 and IL-33 were significantly decreased among patients with GWs in comparison with the controls (p < .0001). There was a highly significant positive correlation between IL-21 and IL-33 (r = .73, p < .0001). Low levels of serum IL-21 and IL-33 could have a contributive role in development, persistence, severity, and recurrence of GWs which rely basically on the defectiveness of cell-mediated immunity. This could receive new light on nonconventional strategies for the prospective medical therapies of GWs by means of regulation of IL-21 and IL-33.
MeSH term(s)	Adult ; Biomarkers/blood ; Case-Control Studies ; Condylomata Acuminata/blood ; Condylomata Acuminata/epidemiology ; Condylomata Acuminata/physiopathology ; Cross-Sectional Studies ; Disease Progression ; Egypt ; Female ; Humans ; Interleukin-33/blood ; Interleukins/blood ; Male ; Middle Aged ; Prognosis ; Reference Values ; Sampling Studies ; Sensitivity and Specificity ; Severity of Illness Index ; Sexually Transmitted Diseases/blood ; Sexually Transmitted Diseases/epidemiology ; Sexually Transmitted Diseases/physiopathology
Chemical Substances	Biomarkers ; Interleukin-33 ; Interleukins ; interleukin-21 (MKM3CA6LT1)
Language	English
Publishing date	2019-08-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	1354801-3
ISSN	1529-8019 ; 1396-0296
ISSN (online)	1529-8019
ISSN	1396-0296
DOI	10.1111/dth.13063
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 5181: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito