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  1. AU="Sedor, John R."
  2. AU="Legrand, Julien"
  3. AU="Mintz, Kevin Todd"
  4. AU="Kösters, Markus"
  5. AU="Castano-Duque, Lina"
  6. AU="Lowry, Gregory V"
  7. AU="Gao, Xiaojuan"
  8. AU="Daniłowicz-Szymanowicz, Ludmiła"
  9. AU="Weber, Jesse N"
  10. AU="Fages-Masmiquel, Ester"
  11. AU="Macias Gil, Raul"
  12. AU="Planchat, Arnaud"
  13. AU="McElrath, Erin E"
  14. AU="Koji Ueda"
  15. AU="Pillas, Diana J"
  16. AU="Thomson, Jason J"
  17. AU="Mitra, Kalyan"
  18. AU="Sanjay Desai"
  19. AU=Cox David J AU=Cox David J
  20. AU="Grebenok, Robert J."
  21. AU="Blackburne, Brittney"
  22. AU="Bortoleti, Bruna Taciane da Silva"
  23. AU="Ehrbar, Martin"
  24. AU="Lepre, Davide"
  25. AU="Olszewska, Zuzanna"
  26. AU="Vojta, Leslie"
  27. AU=Wickstrom Eric AU=Wickstrom Eric
  28. AU="Gangavarapu, Sridevi"
  29. AU="Hussein, Hazem Abdelwaheb"
  30. AU=Cai Yixin AU=Cai Yixin
  31. AU="Hüls, Anke"
  32. AU="Poondru, Srinivasu"
  33. AU="Coca, Daniel"
  34. AU="Lebeau, Paul"
  35. AU="Dehghani, Sedigheh"
  36. AU="Ishibashi, Kenji"
  37. AU="Xu, Yanhua"
  38. AU="Matera, Katarzyna"
  39. AU="Ait-Ouarab, Slimane"
  40. AU="Nicola, Coppede"
  41. AU="Dewitt, John M"
  42. AU="Sorin M. Dudea"
  43. AU="Tanusha D. Ramdin"
  44. AU="Hao, Zehui"
  45. AU="Chauhan, Aman"

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  1. Artikel ; Online: Kidney Genetics: Continuing Discoveries and a Roadmap to the Clinic.

    Sedor, John R

    Journal of the American Society of Nephrology : JASN

    2023  Band 34, Heft 4, Seite(n) 519–520

    Mesh-Begriff(e) Kidney ; Ambulatory Care Facilities
    Sprache Englisch
    Erscheinungsdatum 2023-02-09
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000077
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: APOL1 Kidney Disease: Discovery to Targeted Therapy in 10 Years.

    Sedor, John R

    Clinical journal of the American Society of Nephrology : CJASN

    2023  

    Sprache Englisch
    Erscheinungsdatum 2023-07-17
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.0000000000000256
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Buch: Renal genetics and clinical practice

    Sedor, John R.

    (Nephron journals ; 118,1)

    2011  

    Verfasserangabe guest ed. John Sedor
    Serientitel Nephron journals ; 118,1
    Nephron
    Überordnung Nephron
    Sprache Englisch
    Umfang c66 S. : Ill., graph. Darst.
    Verlag Karger
    Erscheinungsort Basel u.a.
    Erscheinungsland Schweiz
    Dokumenttyp Buch
    HBZ-ID HT016778495
    ISBN 978-3-8055-9647-3 ; 9783805596480 ; 3-8055-9647-2 ; 3805596480
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  4. Artikel ; Online: APOL1

    Gadegbeku, Crystal A / Sedor, John R

    Clinical journal of the American Society of Nephrology : CJASN

    2023  Band 16, Heft 12, Seite(n) 1779–1780

    Mesh-Begriff(e) Humans ; Apolipoprotein L1/genetics ; COVID-19 ; Kidney ; Acute Kidney Injury ; Apolipoproteins/genetics ; Genetic Predisposition to Disease ; Genotype
    Chemische Substanzen Apolipoprotein L1 ; Apolipoproteins ; APOL1 protein, human
    Sprache Englisch
    Erscheinungsdatum 2023-01-11
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.13571021
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Biobanks Linked to Electronic Health Records Accelerate Genomic Discovery.

    Crawford, Dana C / Sedor, John R

    Journal of the American Society of Nephrology : JASN

    2021  Band 32, Heft 8, Seite(n) 1828–1829

    Mesh-Begriff(e) Biological Specimen Banks ; Electronic Health Records ; Genome-Wide Association Study ; Genomics
    Sprache Englisch
    Erscheinungsdatum 2021-07-09
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2021060836
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Biologic Underpinnings of Type 1 Diabetic Kidney Disease.

    Sedor, John R / Freedman, Barry I

    Journal of the American Society of Nephrology : JASN

    2019  Band 30, Heft 10, Seite(n) 1782–1783

    Mesh-Begriff(e) Biological Products ; Collagen ; Diabetes Mellitus, Type 2 ; Diabetic Nephropathies ; Genome-Wide Association Study ; Glomerular Basement Membrane ; Humans ; Kidney Failure, Chronic
    Chemische Substanzen Biological Products ; Collagen (9007-34-5)
    Sprache Englisch
    Erscheinungsdatum 2019-09-19
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2019080803
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: APOL1 and Preeclampsia: Intriguing Links, Uncertain Causality, Troubling Implications.

    Sedor, John R / Bruggeman, Leslie A / O'Toole, John F

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2021  Band 77, Heft 6, Seite(n) 863–865

    Mesh-Begriff(e) Apolipoprotein L1/genetics ; Female ; Genetic Predisposition to Disease ; Genetic Variation ; Humans ; Pre-Eclampsia/epidemiology ; Pre-Eclampsia/genetics ; Pregnancy
    Chemische Substanzen APOL1 protein, human ; Apolipoprotein L1
    Sprache Englisch
    Erscheinungsdatum 2021-04-17
    Erscheinungsland United States
    Dokumenttyp Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2021.01.013
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Apolipoprotein L1 and mechanisms of kidney disease susceptibility.

    Bruggeman, Leslie A / Sedor, John R / O'Toole, John F

    Current opinion in nephrology and hypertension

    2021  Band 30, Heft 3, Seite(n) 317–323

    Abstract: Purpose of review: Allelic variants in the gene for apolipoprotein L1 (APOL1), found only in individuals of African ancestry, explain a majority of the excess risk of kidney disease in African Americans. However, a clear understanding how the disease- ... ...

    Abstract Purpose of review: Allelic variants in the gene for apolipoprotein L1 (APOL1), found only in individuals of African ancestry, explain a majority of the excess risk of kidney disease in African Americans. However, a clear understanding how the disease-associated APOL1 variants cause kidney injury and the identity of environmental stressors that trigger the injury process have not been determined.
    Recent findings: Basic mechanistic studies of APOL1 biochemistry and cell biology, bolstered by new antibody reagents and inducible pluripotent stem cell-derived cell systems, have focused on the cytotoxic effect of the risk variants when APOL1 gene expression is induced. Since the APOL1 variants evolved to alter a key protein-protein interaction with the trypanosome serum resistance-associated protein, additional studies have begun to address differences in APOL1 interactions with other proteins expressed in podocytes, including new observations that APOL1 variants may alter podocyte cytoskeleton dynamics.
    Summary: A unified mechanism of pathogenesis for the various APOL1 nephropathies still remains unclear and controversial. As ongoing studies have consistently implicated the pathogenic gain-of-function effects of the variant proteins, novel therapeutic development inhibiting the synthesis or function of APOL1 proteins is moving toward clinical trials.
    Mesh-Begriff(e) Apolipoprotein L1/genetics ; Disease Susceptibility ; Genetic Predisposition to Disease ; Humans ; Kidney Diseases/genetics ; Kidney Diseases/therapy ; Podocytes
    Chemische Substanzen APOL1 protein, human ; Apolipoprotein L1
    Sprache Englisch
    Erscheinungsdatum 2021-03-24
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1151092-4
    ISSN 1473-6543 ; 1535-3842 ; 1062-4813 ; 1062-4821
    ISSN (online) 1473-6543 ; 1535-3842
    ISSN 1062-4813 ; 1062-4821
    DOI 10.1097/MNH.0000000000000704
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Uromodulin and translational medicine: will the SNPs bring zip to clinical practice?

    Sedor, John R

    Journal of the American Society of Nephrology : JASN

    2010  Band 21, Heft 2, Seite(n) 204–206

    Mesh-Begriff(e) Chronic Disease ; Genetic Predisposition to Disease/genetics ; Humans ; Kidney Diseases/genetics ; Kidney Diseases, Cystic/genetics ; Molecular Motor Proteins/genetics ; Mucoproteins/genetics ; Myosin Heavy Chains/genetics ; Polymorphism, Single Nucleotide/genetics ; Risk Factors ; Uromodulin
    Chemische Substanzen MYH9 protein, human ; Molecular Motor Proteins ; Mucoproteins ; UMOD protein, human ; Uromodulin ; Myosin Heavy Chains (EC 3.6.4.1)
    Sprache Englisch
    Erscheinungsdatum 2010-02
    Erscheinungsland United States
    Dokumenttyp Comment ; Editorial
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2009121283
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Buch: Nephrology secrets

    Hricik, Donald E. / Sedor, John R. / Ganz, Michael B.

    [questions you will be asked on rounds, in the clinic, on oral exams]

    (The secrets series)

    1999  

    Verfasserangabe Donald E. Hricik ; John R. Sedor ; Michael B. Ganz
    Serientitel The secrets series
    Schlagwörter Kidney Diseases Examination Questions
    Sprache Englisch
    Umfang XI, 259 S. : Ill., graph. Darst.
    Verlag Hanley & Belfus
    Erscheinungsort Philadelphia
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT011179455
    ISBN 1-560-53309-9 ; 978-1-560-53309-2
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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