Article ; Online: Toxic leukoencephalopathy due to transdermal fentanyl overdose.
2011 Volume 27, Issue 9, Page(s) 854–856
Abstract: Children with altered mental status who present to the emergency department have a broad differential diagnosis. We report a case of a 19-month-old girl who presented in coma and who was later found to have a fentanyl patch adhered to her back. She was ... ...
Abstract | Children with altered mental status who present to the emergency department have a broad differential diagnosis. We report a case of a 19-month-old girl who presented in coma and who was later found to have a fentanyl patch adhered to her back. She was found to have changes on brain magnetic resonance imaging consistent with a toxic spongiform leukoencephalopathy but had a good neurologic outcome. This case report illustrates the importance of a thorough physical examination in children in coma and a rarely reported magnetic resonance imaging finding that has been seen in opioid intoxication and is usually associated with severe morbidity and mortality. |
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MeSH term(s) | Accidents, Home ; Administration, Cutaneous ; Apnea/chemically induced ; Child, Preschool ; Coma/chemically induced ; Decerebrate State/chemically induced ; Delayed Diagnosis ; Emergencies ; Female ; Fentanyl/administration & dosage ; Fentanyl/poisoning ; Humans ; Hyperglycemia/chemically induced ; Leukoencephalopathies/chemically induced ; Magnetic Resonance Imaging ; Miosis/chemically induced ; Poisoning/diagnosis ; Reflex, Abnormal/drug effects ; Unnecessary Procedures |
Chemical Substances | Fentanyl (UF599785JZ) |
Language | English |
Publishing date | 2011-09 |
Publishing country | United States |
Document type | Case Reports ; Journal Article |
ZDB-ID | 632588-9 |
ISSN | 1535-1815 ; 0749-5161 |
ISSN (online) | 1535-1815 |
ISSN | 0749-5161 |
DOI | 10.1097/PEC.0b013e31822c281f |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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