LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 13

Search options

  1. Article ; Online: An Unusual Uterine Cavity Phenomenon.

    Segev, Eran Meir / Goldberg, Yael / Lavie, Ofer

    Journal of minimally invasive gynecology

    2015  Volume 22, Issue 7, Page(s) 1130–1131

    Language English
    Publishing date 2015-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2186934-0
    ISSN 1553-4669 ; 1553-4650
    ISSN (online) 1553-4669
    ISSN 1553-4650
    DOI 10.1016/j.jmig.2015.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Optical phased array neural probes for beam-steering in brain tissue.

    Sacher, Wesley D / Chen, Fu-Der / Moradi-Chameh, Homeira / Liu, Xinyu / Felts Almog, Ilan / Lordello, Thomas / Chang, Michael / Naderian, Azadeh / Fowler, Trevor M / Segev, Eran / Xue, Tianyuan / Mahallati, Sara / Valiante, Taufik A / Moreaux, Laurent C / Poon, Joyce K S / Roukes, Michael L

    Optics letters

    2022  Volume 47, Issue 5, Page(s) 1073–1076

    Abstract: Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering ... ...

    Abstract Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering in vitro. Beam formation in brain tissue is simulated and characterized. The probes are used for optogenetic stimulation and calcium imaging.
    MeSH term(s) Brain/diagnostic imaging ; Optogenetics ; Silicon
    Chemical Substances Silicon (Z4152N8IUI)
    Language English
    Publishing date 2022-02-18
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.441609
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Optogenetic manipulation of medullary neurons in the locust optic lobe.

    Wang, Hongxia / Dewell, Richard B / Ehrengruber, Markus U / Segev, Eran / Reimer, Jacob / Roukes, Michael L / Gabbiani, Fabrizio

    Journal of neurophysiology

    2018  Volume 120, Issue 4, Page(s) 2049–2058

    Abstract: The locust is a widely used animal model for studying sensory processing and its relation to behavior. Due to the lack of genomic information, genetic tools to manipulate neural circuits in locusts are not yet available. We examined whether Semliki ... ...

    Abstract The locust is a widely used animal model for studying sensory processing and its relation to behavior. Due to the lack of genomic information, genetic tools to manipulate neural circuits in locusts are not yet available. We examined whether Semliki Forest virus is suitable to mediate exogenous gene expression in neurons of the locust optic lobe. We subcloned a channelrhodopsin variant and the yellow fluorescent protein Venus into a Semliki Forest virus vector and injected the virus into the optic lobe of locusts ( Schistocerca americana). Fluorescence was observed in all injected optic lobes. Most neurons that expressed the recombinant proteins were located in the first two neuropils of the optic lobe, the lamina and medulla. Extracellular recordings demonstrated that laser illumination increased the firing rate of medullary neurons expressing channelrhodopsin. The optogenetic activation of the medullary neurons also triggered excitatory postsynaptic potentials and firing of a postsynaptic, looming-sensitive neuron, the lobula giant movement detector. These results indicate that Semliki Forest virus is efficient at mediating transient exogenous gene expression and provides a tool to manipulate neural circuits in the locust nervous system and likely other insects. NEW & NOTEWORTHY Using Semliki Forest virus, we efficiently delivered channelrhodopsin into neurons of the locust optic lobe. We demonstrate that laser illumination increases the firing of the medullary neurons expressing channelrhodopsin and elicits excitatory postsynaptic potentials and spiking in an identified postsynaptic target neuron, the lobula giant movement detector neuron. This technique allows the manipulation of neuronal activity in locust neural circuits using optogenetics.
    MeSH term(s) Animals ; Brain/physiology ; Channelrhodopsins/genetics ; Channelrhodopsins/metabolism ; Excitatory Postsynaptic Potentials ; Genetic Vectors/genetics ; Grasshoppers ; Optogenetics/methods ; Protein Engineering/methods ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Semliki forest virus/genetics ; Sensory Receptor Cells/metabolism ; Sensory Receptor Cells/physiology ; Visual Perception
    Chemical Substances Channelrhodopsins ; Recombinant Proteins
    Language English
    Publishing date 2018-08-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 80161-6
    ISSN 1522-1598 ; 0022-3077
    ISSN (online) 1522-1598
    ISSN 0022-3077
    DOI 10.1152/jn.00356.2018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: The effect of bladder fullness on evaluation of pelvic organ prolapse.

    Haya, Nir / Segev, Eran / Younes, Grace / Goldschmidt, Eyal / Auslender, Ron / Abramov, Yoram

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2012  Volume 118, Issue 1, Page(s) 24–26

    Abstract: Objective: To investigate the effect of bladder fullness on pelvic organ prolapse (POP) staging via the Pelvic Organ Prolapse Quantification System (POP-Q).: Methods: Sixty women with advanced POP underwent pelvic examination with maximal Valsalva ... ...

    Abstract Objective: To investigate the effect of bladder fullness on pelvic organ prolapse (POP) staging via the Pelvic Organ Prolapse Quantification System (POP-Q).
    Methods: Sixty women with advanced POP underwent pelvic examination with maximal Valsalva straining via POP-Q with an empty bladder and after transcatheter bladder filling to maximum cystometric capacity, with simultaneous intra-abdominal and intravesical pressure recordings. Main outcome measures included POP-Q values and staging with full versus empty bladder.
    Results: An empty bladder was associated with a significantly higher POP-Q staging (median, 3 vs 2; P<0.0001); and a lower location of points Ba (4.51 vs 1.37; P<0.0001), Aa (2.58 vs 0.62; P<0.0001), Bp (-0.68 vs -1.10; P=0.01), Ap (0.83 vs -1.27; P=0.002), C (1.57 vs -1.07; P<0.0001), and D (0.14 vs -2.77; P<0.0001) compared with a full bladder. However, genital hiatus, perineal body, and total vaginal length values were not significantly affected by bladder fullness. No differences in intra-abdominal or detrusor pressures were noted between empty and full bladder states.
    Conclusion: POP-Q assessment with a full bladder is associated with underestimation of POP severity. Therefore, bladder emptying should be a standard requirement for POP-Q staging and reporting.
    MeSH term(s) Aged ; Female ; Humans ; Middle Aged ; Outcome Assessment (Health Care) ; Pelvic Organ Prolapse/pathology ; Prospective Studies ; Severity of Illness Index ; Urinary Bladder ; Urinary Catheterization
    Language English
    Publishing date 2012-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1016/j.ijgo.2012.02.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Location determinants of new foreign-owned manufacturing plants

    Coughlin, Cletus C / Segev, Eran

    Journal of regional science Vol. 40, No. 2 , p. 323-351

    2000  Volume 40, Issue 2, Page(s) 323–351

    Author's details Cletus C. Coughlin; Eran Segev
    Keywords Produktionsstandort ; Auslandsinvestition ; Räumliche Verteilung ; Standortfaktor ; USA
    Language English
    Size Kt
    Publisher Blackwell
    Publishing place Malden, Mass. [u.a.]
    Document type Article
    ZDB-ID 219215-9
    Database ECONomics Information System

    More links

    Kategorien

  6. Article: Foreign direct investment in China

    Coughlin, Cletus C / Segev, Eran

    The world economy : the leading journal on international economic relations Vol. 23, No. 1 , p. 1-23

    a spatial econometric study

    2000  Volume 23, Issue 1, Page(s) 1–23

    Author's details Cletus C. Coughlin and Eran Segev
    Keywords Auslandsinvestition ; Regionales Cluster ; Räumliche Verteilung ; China
    Language English
    Size Graph. Darst., Kt
    Publisher Blackwell
    Publishing place Oxford
    Document type Article
    ZDB-ID 132896-7
    Database ECONomics Information System

    More links

    Kategorien

  7. Book: Foreign direct investment in China

    Coughlin, Cletus C / Segev, Eran

    a spatial econometric study

    (Research Division working papers ; 99,001B)

    1999  

    Author's details Cletus C. Coughlin; Eran Segev
    Series title Research Division working papers ; 99,001B
    Keywords 1979-1996 ; 24;34;59;60
    Language English
    Size 31, [9] Bl, graph. Darst
    Publisher Federal Reserve Bank of St. Louis
    Publishing place St. Louis, MO
    Document type Book
    Database ECONomics Information System

    More links

    Kategorien

  8. Article: Patterned photostimulation via visible-wavelength photonic probes for deep brain optogenetics.

    Segev, Eran / Reimer, Jacob / Moreaux, Laurent C / Fowler, Trevor M / Chi, Derrick / Sacher, Wesley D / Lo, Maisie / Deisseroth, Karl / Tolias, Andreas S / Faraon, Andrei / Roukes, Michael L

    Neurophotonics

    2016  Volume 4, Issue 1, Page(s) 11002

    Abstract: Optogenetic methods developed over the past decade enable unprecedented optical activation and silencing of specific neuronal cell types. However, light scattering in neural tissue precludes illuminating areas deep within the brain via free-space optics; ...

    Abstract Optogenetic methods developed over the past decade enable unprecedented optical activation and silencing of specific neuronal cell types. However, light scattering in neural tissue precludes illuminating areas deep within the brain via free-space optics; this has impeded employing optogenetics universally. Here, we report an approach surmounting this significant limitation. We realize implantable, ultranarrow, silicon-based photonic probes enabling the delivery of complex illumination patterns deep within brain tissue. Our approach combines methods from integrated nanophotonics and microelectromechanical systems, to yield photonic probes that are robust, scalable, and readily producible
    Language English
    Publishing date 2016-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2781943-7
    ISSN 2329-4248 ; 2329-423X
    ISSN (online) 2329-4248
    ISSN 2329-423X
    DOI 10.1117/1.NPh.4.1.011002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Book: Location determinants of new foreign-owned manufacturing plants

    Coughlin, Cletus C / Segev, Eran

    (Research Division working papers ; 97,018B)

    1997  

    Author's details Cletus C. Coughlin; Eran Segev
    Series title Research Division working papers ; 97,018B
    Keywords Produktionsstandort ; Auslandsinvestition ; Räumliche Verteilung ; Standortfaktor ; USA
    Language English
    Size 30, [10] Bl, graph. Darst
    Publisher Federal Reserve Bank of St. Louis
    Publishing place St. Louis, MO
    Document type Book
    Database ECONomics Information System

    More links

    Kategorien

  10. Article: [THE ROLE OF SIMULATION IN SURGICAL TRAINING--A NEW ERA].

    Rofe, Guy / Lissak, Arie / Brandes-Klein, Orly / Segev, Eran / Paz, Moran / Hod, Yael / Barzilai, Menashe / Auslender, Ron / Shapira, Chen / Kaufman, Yuval

    Harefuah

    2015  Volume 154, Issue 6, Page(s) 398–403

    Abstract: Surgical training, which was traditionally based on the apprentice model, is undergoing a fundamental change since the introduction of virtual reality simulators into the training program of surgical residents. With the introduction of these simulators ... ...

    Abstract Surgical training, which was traditionally based on the apprentice model, is undergoing a fundamental change since the introduction of virtual reality simulators into the training program of surgical residents. With the introduction of these simulators we can expect to see an improvement in the surgical abilities of new surgeons and a decrease in costs--as seen in the aviation world. Virtual reality simulators include a visual and tactile interface which is meant to train young surgeons in full procedure before the actual surgery. The available operation encompasses a multitude of surgical disciplines--gynecology, urology, orthopedics, vascular surgery, general surgery and more. The simulator allows the surgeon to practice complicated procedures and to be exposed to emergency situations without risking the patient's life. We opened in the Carmel Medical Center a multi disciplinary simulation center 18 months ago. The center includes simulators for gynecology, orthopedics, urology, general surgery, vascular surgery and advanced cardiac life support. The center cooperates with the Faculty of Medicine at the Technion in order to train young surgeons in all surgical disciplines. In this period of time we followed the improvement in the endoscopic abilities of the basic skills course participants.
    MeSH term(s) Clinical Competence ; Computer Simulation ; Curriculum ; Education, Medical/methods ; Endoscopy/education ; General Surgery/education ; Humans ; Israel ; User-Computer Interface
    Language Hebrew
    Publishing date 2015-06
    Publishing country Israel
    Document type English Abstract ; Journal Article
    ZDB-ID 953872-0
    ISSN 0017-7768
    ISSN 0017-7768
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top