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  1. AU="Seibert, Julie"
  2. AU="Nazrul Islam"
  3. AU="Qadir, Syed Saeed"
  4. AU="Koutsoukos, Marguerite"
  5. AU="Webster, Kara"
  6. AU=Tremoulet Adriana H.
  7. AU="Foggia, Maria"
  8. AU=Eccles Michael R
  9. AU="Karrison, Theodore"
  10. AU="Espigado, I"
  11. AU="Dean, Andrew"

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  1. Artikel: A case series in individuals with multiple sclerosis using direct current electrical stimulation to inhibit spasticity and improve functional outcomes.

    Ellerbusch, Courtney L / Chapple, Kristina M / Seibert, Julie B

    Multiple sclerosis journal - experimental, translational and clinical

    2023  Band 9, Heft 3, Seite(n) 20552173231186512

    Abstract: Background and purpose: Multiple sclerosis (MS) has a high incidence of debilitating spasticity. Central Nervous System (CNS) intrafusal settings have an impact on spasticity level. Mechanoreceptors of the Peripheral Nervous System (PNS) communicate ... ...

    Abstract Background and purpose: Multiple sclerosis (MS) has a high incidence of debilitating spasticity. Central Nervous System (CNS) intrafusal settings have an impact on spasticity level. Mechanoreceptors of the Peripheral Nervous System (PNS) communicate monosynaptically with the central nervous system (CNS). This case series assesses feasibility of multimodal treatment of individuals with MS using a direct current electrical stimulation (DC) to influence mechanoreceptors.
    Case description and intervention: Seven MS diagnosed participants with Expanded Disability Status Scale (EDSS) = 6.0-8.0 completed 18 visits over 6 weeks of using DC combined with neuromuscular reeducation. Design included pre-, post- outcome measures of EDSS, 12-item MS Walking Scale (MSWS-12), Range of Motion (ROM), Manual Muscle Testing (MMT), Modified Ashworth Test (MAT), Timed 25-Foot walk (T25WT), Timed Up and Go (TUG) and the Multiple Sclerosis Impact Scale-29 (MSIS-29).
    Outcome: 125 out of a possible 126 visits were completed, demonstrating a high level of tolerance. Individual results included trends towards improvement in spasticity and agonists.
    Discussion: This case series design of seven heterogenous subjects with MS is a low sample size for statistical analysis and should be considered a pilot. The study demonstrates a high level of feasibility and possible correlations to consider. Further research is warranted.
    Sprache Englisch
    Erscheinungsdatum 2023-07-13
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2841884-0
    ISSN 2055-2173 ; 2055-2173
    ISSN (online) 2055-2173
    ISSN 2055-2173
    DOI 10.1177/20552173231186512
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Characteristics of High-Need, High-Cost Patients : A "Best-Fit" Framework Synthesis.

    Berkman, Nancy D / Chang, Eva / Seibert, Julie / Ali, Rania

    Annals of internal medicine

    2022  

    Abstract: Background: Accurately identifying high-need, high-cost (HNHC) patients to reduce their preventable or modifiable health care use for their chronic conditions is a priority and a challenge for U.S. policymakers, health care delivery systems, and payers.! ...

    Abstract Background: Accurately identifying high-need, high-cost (HNHC) patients to reduce their preventable or modifiable health care use for their chronic conditions is a priority and a challenge for U.S. policymakers, health care delivery systems, and payers.
    Purpose: To identify characteristics and criteria to distinguish HNHC patients.
    Data sources: Searches of multiple databases and gray literature from 1 January 2000 to 22 January 2022.
    Study selection: English-language studies of characteristics and criteria to identify HNHC adult patients, defined as those with high use (emergency department, inpatient, or total services) or high cost.
    Data extraction: Independent, dual-review extraction and quality assessment.
    Data synthesis: The review included 64 studies comprising multivariate exposure studies (
    Limitation: Little evidence distinguished potentially preventable or modifiable health care use from overall use.
    Conclusion: A combination of characteristics can be useful for identifying HNHC patients. Because of the complexity of their conditions and circumstances, improving their quality of care will likely also require an individualized assessment of care needs and availability of support services.
    Primary funding source: Agency for Healthcare Research and Quality. (PROSPERO: CRD42020161179).
    Sprache Englisch
    Erscheinungsdatum 2022-11-08
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/M21-4562
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Development and validation of a claim-based provider-level measurement of use of medications to treat opioid use disorder.

    Dowd, William N / Barch, Daniel H / Seibert, Julie H / Mark, Tami L

    Journal of substance abuse treatment

    2022  Band 140, Seite(n) 108824

    Abstract: Objective: Medication for opioid use disorder (MOUD) is effective but underused. Measuring the percentage of a provider's patients with an opioid use disorder (OUD) who receive MOUD may drive quality improvement and stimulate greater use of medications. ...

    Abstract Objective: Medication for opioid use disorder (MOUD) is effective but underused. Measuring the percentage of a provider's patients with an opioid use disorder (OUD) who receive MOUD may drive quality improvement and stimulate greater use of medications. This study introduces and tests a provider-level measure of MOUD receipt.
    Methods: The study used claims and enrollment data from 32 states in the 2014 Medicaid Analytic Extract to measure the proportion of a provider's patients who received MOUD within 30 days of their OUD diagnosis. The research team assessed measure reliability with several tests to establish the effect of provider on MOUD receipt; and assessed the validity by correlation with a measure of emergency department visits or hospitalizations related to substance use.
    Results: The sample included 434,484 individuals treated for OUD by one or more of 9398 providers. The mean provider score was 38 %, indicating that 38 % of the average provider's patients received an MOUD within 30 days of an OUD diagnosis (44 % for clinicians [N = 5344] and 31 % for facilities [N = 4054]). Provider performance varied considerably. The interquartile ranges were 11 %-79 % and 9 %-45 % among clinicians and facilities, respectively. The measure reliably distinguished between lower- and higher-performing providers and demonstrated convergent validity, as indicated by a significant and moderately sized negative correlation between MOUD receipt and substance use-related hospitalizations or emergency department visits.
    Conclusions: The measure may help to improve access to MOUD and OUD outcomes by identifying providers who could benefit from technical assistance, quality improvement initiatives, and resources to expand MOUD prescribing.
    Mesh-Begriff(e) Analgesics, Opioid/therapeutic use ; Buprenorphine/therapeutic use ; Drug Prescriptions ; Humans ; Opiate Substitution Treatment ; Opioid-Related Disorders/drug therapy ; Reproducibility of Results ; United States
    Chemische Substanzen Analgesics, Opioid ; Buprenorphine (40D3SCR4GZ)
    Sprache Englisch
    Erscheinungsdatum 2022-06-16
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605923-5
    ISSN 1873-6483 ; 0740-5472
    ISSN (online) 1873-6483
    ISSN 0740-5472
    DOI 10.1016/j.jsat.2022.108824
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Interventions to Improve Outcomes for High-Need, High-Cost Patients: A Systematic Review and Meta-Analysis.

    Chang, Eva / Ali, Rania / Seibert, Julie / Berkman, Nancy D

    Journal of general internal medicine

    2022  Band 38, Heft 1, Seite(n) 185–194

    Abstract: Background: Chronic disease patients who are the greatest users of healthcare services are often referred to as high-need, high-cost (HNHC). Payers, providers, and policymakers in the United States are interested in identifying interventions that can ... ...

    Abstract Background: Chronic disease patients who are the greatest users of healthcare services are often referred to as high-need, high-cost (HNHC). Payers, providers, and policymakers in the United States are interested in identifying interventions that can modify or reduce preventable healthcare use among these patients, without adversely impacting their quality of care and health. We systematically reviewed the evidence on the effectiveness of complex interventions designed to change the healthcare of HNHC patients, modifying cost and utilization, as well as clinical/functional, and social risk factor outcomes.
    Methods: We searched 8 electronic databases (January 2000 to March 2021) and selected non-profit organization and government agency websites for randomized controlled trials and observational studies with comparison groups that targeted HNHC patients. Two investigators independently screened each study and abstracted data into structured forms. Study quality was assessed using standard risk of bias tools. Random-effects meta-analysis was conducted for outcomes reported by at least 3 comparable samples.
    Results: Forty studies met our inclusion criteria. Interventions were heterogenous and classified into 7 categories, reflecting the predominant service location/modality (home, primary care, ambulatory intensive caring unit [aICU], emergency department [ED], community, telephonic/mail, and system-level). Home-, primary care-, and ED-based interventions resulted in reductions in high-cost healthcare services (ED and hospital use). ED-based interventions also resulted in greater use of primary care. Primary care- and ED-based interventions reduced costs. System-level transformation interventions did not reduce costs.
    Discussion: We found limited evidence of intervention effectiveness in relation to cost and use, and additional evidence is needed to strengthen our confidence in the findings. Few studies reported patient clinical/functional or social risk factor outcomes (e.g., homelessness) or sufficient details for determining why individual interventions work, for whom, and when. Future evaluations could provide additional insights, by including intermediate process outcomes and patients' experiences, in assessing the impact of these complex interventions.
    Prospero registration number: CRD42020161179.
    Mesh-Begriff(e) Humans ; United States ; Delivery of Health Care ; Health Services ; Emergency Service, Hospital ; Emergency Medical Services
    Sprache Englisch
    Erscheinungsdatum 2022-10-11
    Erscheinungsland United States
    Dokumenttyp Meta-Analysis ; Systematic Review ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-022-07809-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Mental health emergency department visits: An exploration of case definitions in North Carolina.

    LeMasters, Katherine / Cox, Mary E / Fliss, Mike / Seibert, Julie / Brown, Carrie / Proescholdbell, Scott

    The American journal of emergency medicine

    2022  Band 57, Seite(n) 103–106

    Abstract: Background: Mental health (MH) disorders comprise a high disease burden and have long-lasting impacts. To improve MH, it is important to define public health MH surveillance.: Methods: We compared MH related definitions using ICD-10-CM codes: The ... ...

    Abstract Background: Mental health (MH) disorders comprise a high disease burden and have long-lasting impacts. To improve MH, it is important to define public health MH surveillance.
    Methods: We compared MH related definitions using ICD-10-CM codes: The Council of State and Territorial Epidemiologists' (CSTE) surveillance indicators for all MH, mood or depressive, schizophrenic, and drug/alcohol-induced disorders; and North Carolina's (NC) syndromic surveillance system's definition for anxiety/mood/psychotic disorders, and suicide/self-harm. We compared code definitions and frequent codes in 2019 emergency department (ED) data for those age ≥ 10 years.
    Results: CSTE's definition resulted in over one million MH-related visits (23% of all ED visits) and NC's definitions in 451,807 MH-related visits (9% of all ED visits). Using CSTE's broadest definition, nicotine use was the most common visit type; using NC's definitions, it was major depressive disorder.
    Conclusions: Standardizing population-level MH indicators benefits surveillance efforts. Given its prevalence, efforts should focus on documenting MH to improve treatment and prevention.
    Mesh-Begriff(e) Child ; Depressive Disorder, Major ; Emergency Service, Hospital ; Humans ; International Classification of Diseases ; Mental Health ; North Carolina/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2022-05-05
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2022.04.053
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Findings From Implementing a Patient Experience Survey in a Quality Measurement System for Substance Abuse Disorder Treatment Facilities in 6 States.

    Zuckerbraun, Sara / Eicheldinger, Celia / Barch, Daniel / Mark, Tami / Seibert, Julie / Thornburg, Vanessa / Carley-Baxter, Lisa

    Journal of addiction medicine

    2022  Band 17, Heft 3, Seite(n) 271–277

    Abstract: Objectives: Patient experience surveys (PESs) are an important component of determining the quality of health care. There is an absence of PES data available to people seeking to identify higher quality substance use disorder treatment providers. Our ... ...

    Abstract Objectives: Patient experience surveys (PESs) are an important component of determining the quality of health care. There is an absence of PES data available to people seeking to identify higher quality substance use disorder treatment providers. Our project aimed to correct this by implementing a PES for substance use disorder treatment providers and publicly disseminating PES information.
    Methods: We created a population frame of all addiction providers in 6 states. Providers were asked to disseminate a survey invitation letter directing patients to a survey Web site. No personally identifiable information was exchanged. We developed a 10-question survey, reflecting characteristics National Institute on Drug Abuse (NIDA), National Institute on Alcohol Abuse and Alcoholism (NIAAA), Substance Abuse and Mental Health Services Administration (SAMHSA) have identified as reflecting higher-quality addiction treatment.
    Results: Nineteen percent of facilities participated; among participating facilities, 9627 patients completed the survey. Patient experience varied significantly by facility with the percentage of a facility's patients who chose the most positive answer varying widely. We calculated that between-facility reliability will meet or exceed 0.80 for facilities with 20 or more responding patients. We searched for but did not find evidence of data falsification.
    Conclusions: This cost-efficient survey protocol is low burden for providers and patients. Results suggest significant differences in quality of care among facilities, and facility-level results are important to provide to consumers when they evaluate the relative patient-reported quality of facilities. The data are not designed to provide population-based statistics. As more facilities and patients per facility participate, public-facing PES data will be increasingly useful to consumers seeking to compare and choose facilities.
    Mesh-Begriff(e) Humans ; United States ; Reproducibility of Results ; Surveys and Questionnaires ; Substance-Related Disorders/therapy ; Patient Outcome Assessment
    Sprache Englisch
    Erscheinungsdatum 2022-10-16
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1935-3227
    ISSN (online) 1935-3227
    DOI 10.1097/ADM.0000000000001094
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Severe anemia in a patient with multiple sclerosis treated with natalizumab.

    Seibert, Julie B / Alvarez, Enrique

    Neurology

    2015  Band 84, Heft 8, Seite(n) 861

    Mesh-Begriff(e) Anemia/etiology ; Antibodies, Monoclonal, Humanized/adverse effects ; Female ; Humans ; Immunosuppressive Agents/adverse effects ; Multiple Sclerosis, Relapsing-Remitting/drug therapy
    Chemische Substanzen Antibodies, Monoclonal, Humanized ; Immunosuppressive Agents
    Sprache Englisch
    Erscheinungsdatum 2015-02-24
    Erscheinungsland United States
    Dokumenttyp Comment ; Letter
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/01.wnl.0000461938.49936.52
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Cross-setting Comparison of Risk Factors for Pressure Injuries Acquired in Post-Acute Care.

    Barch, Daniel H / Seibert, Julie Hayes / Kandilov, Amy / Bernacet, Amarilys / Deutsch, Anne / Wang, Xiao Joyce / Scherer, Elissa / McMullen, Tara / Mandl, Stella / Levitt, Alan / Frank, Jennifer / Stephanopoulos, Cynthia / Smith, Laura M

    Advances in skin & wound care

    2023  Band 36, Heft 3, Seite(n) 128–136

    Abstract: General purpose: To provide information on the association between risk factors and the development of new or worsened stage 2 to 4 pressure injuries (PIs) in patients in long-term care hospitals (LTCHs), inpatient rehabilitation facilities (IRFs), and ... ...

    Abstract General purpose: To provide information on the association between risk factors and the development of new or worsened stage 2 to 4 pressure injuries (PIs) in patients in long-term care hospitals (LTCHs), inpatient rehabilitation facilities (IRFs), and skilled nursing facilities (SNFs).
    Target audience: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.
    Learning objectives/outcomes: After participating in this educational activity, the participant will:1. Compare the unadjusted PI incidence in SNF, IRF, and LTCH populations.2. Explain the extent to which the clinical risk factors of functional limitation (bed mobility), bowel incontinence, diabetes/peripheral vascular disease/peripheral arterial disease, and low body mass index are associated with new or worsened stage 2 to 4 PIs across the SNF, IRF, and LTCH populations.3. Compare the incidence of new or worsened stage 2 to 4 PI development in SNF, IRF, and LTCH populations associated with high body mass index, urinary incontinence, dual urinary and bowel incontinence, and advanced age.
    Mesh-Begriff(e) Humans ; United States ; Pressure Ulcer/epidemiology ; Subacute Care ; Fecal Incontinence ; Risk Factors ; Crush Injuries ; Skilled Nursing Facilities
    Sprache Englisch
    Erscheinungsdatum 2023-02-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2012792-3
    ISSN 1538-8654 ; 1527-7941
    ISSN (online) 1538-8654
    ISSN 1527-7941
    DOI 10.1097/01.ASW.0000912008.97430.b4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Development, Testing, and Dissemination of a Public-Facing Tool to Help Consumers Find Higher-Quality Addiction Treatment.

    Mark, Tami L / Seibert, Julie / Dowd, William N / Zuckerbraun, Sara M / Popovic, Jennifer R / Barch, Daniel H

    Psychiatric services (Washington, D.C.)

    2021  Band 73, Heft 3, Seite(n) 293–298

    Abstract: Objective: The authors aimed to describe the development and testing of quality measures included in a public-facing addiction treatment facility search engine.: Methods: An addiction treatment facility survey was created that queried providers in ... ...

    Abstract Objective: The authors aimed to describe the development and testing of quality measures included in a public-facing addiction treatment facility search engine.
    Methods: An addiction treatment facility survey was created that queried providers in six U.S. states about whether they offered the services and used the processes identified by federal agencies and nonprofit organizations as signs of higher-quality addiction treatment. Four insurance claims-based quality measures were created to capture the percentage of a provider's patients with opioid use disorder receiving opioid use disorder medications, who filled prescriptions for such medication for at least 180 days, who received follow-up care after treatment for substance use disorder in inpatient or residential settings, or who had a substance use disorder-related hospitalization or emergency department visit. A patient experience-of-care survey captured patients' perceptions of the quality of the addiction treatment. The project was undertaken from November 2018 through July 2020.
    Results: The authors tested the measures by using 1,245 facility surveys, 7,970 patients' experience-of-care surveys, and four claims-based measures submitted by 129, 136, 283, and 408 addiction treatment providers. Statistical testing demonstrated that the quality measures were reliable and valid. The quality measure scores varied among providers, capturing a wide performance range. A public website containing quality measures launched in July 2020 in the six states and has been accessed by thousands of consumers.
    Conclusions: This study developed valid, reliable, and useful addiction treatment quality measures. Dissemination of these measures may help consumers select among providers and help providers, policy makers, and payers improve quality.
    Mesh-Begriff(e) Aftercare ; Behavior, Addictive ; Humans ; Inpatients ; Opioid-Related Disorders/drug therapy
    Sprache Englisch
    Erscheinungsdatum 2021-07-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1220173-x
    ISSN 1557-9700 ; 1075-2730
    ISSN (online) 1557-9700
    ISSN 1075-2730
    DOI 10.1176/appi.ps.202000879
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Buch ; Online: Environment scan of MLTSS quality requirements in MCO contracts

    Rivard, Pat / Rachel, Jason / Seibert, Julie / Whitworth, Taylor

    2013  

    Abstract: Contracts with managed care organizations (MCOs) in 17 states were reviewed. The scan of managed long-term services and supports (MLTSS) quality requirements revealed wide diversity in some instances and in others more convergence. ...

    Körperschaft United States. / Department of Health and Human Services
    Verfasserangabe Pat Rivard, Beth Jackson, Jason Rachel, Julie Seibert, Taylor Whitworth ; prepared for Office of Disability, Aging and Long-Term Care Policy Office of the Assistant Secretary for Planning and Evaluation U.S. Department of Health and Human Services
    Abstract Contracts with managed care organizations (MCOs) in 17 states were reviewed. The scan of managed long-term services and supports (MLTSS) quality requirements revealed wide diversity in some instances and in others more convergence.
    Mesh-Begriff(e) Long-Term Care/organization & administration ; Managed Care Programs/organization & administration ; Contracts ; Quality Indicators, Health Care
    Schlagwörter United States
    Sprache Englisch
    Umfang 1 online resource (1 PDF file (various pagings)) :, illustrations
    Dokumenttyp Buch ; Online
    Anmerkung Title from PDF title page.
    Datenquelle Katalog der US National Library of Medicine (NLM)

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