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  1. Article: Schlafstörungen

    Seidel, S.

    Neurologisch

    2022  Volume -, Issue 1, Page(s) 92

    Language German
    Document type Article
    ZDB-ID 2475252-6
    ISSN 2223-0629
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7184: Show issues Location:
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  2. Book ; Thesis: Exekutive Dysfunktionen und Ereignis-korrelierte Potenziale bei Patienten mit Amyotropher Lateralsklerose

    Seidel, Stefanie

    2017  

    Author's details vorgelegt von Stefanie Seidel, geb. Fürkötter
    Language German ; English
    Size 53 Blätter, Diagramme, 30 cm
    Publishing place Hannover
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Medizinische Hochschule Hannover, 2018
    Note Enthält Sonderabdruck aus Zeitschrift in englischer Sprache ; Enthält 1 Sonderabdruck aus: Frontiers in Aging Neuroscience ; Volume 7, Articel 225.2015. 17 Seiten
    HBZ-ID HT019728120
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2018 E 786 order for loan Magazin

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  3. Article: Hilfeplan und Bauchgefühl : Schwerpunkt Kindeswohl

    Seidel, Stefaniw

    Hebammenforum: Das Magazin des Bundes Deutscher Hebammen

    2023  Volume 24, Issue 12, Page(s) 12–16

    Keywords Hilfe ; Jena
    Language German
    Document type Article
    ZDB-ID 2104441-7
    ISSN 1611-4566
    ISSN 1611-4566
    Database bibnet.org

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  4. Article: Narkolepsie mit Kataplexien - mehr als nur kurze Schwächeanfälle. Ein Fallbericht. Narcolepsy with Cataplexy - more than just Brief Dizzy Spells. A Case Report

    Seidel, S.

    Psychopraxis.Neuropraxis

    2019  Volume 22, Issue 5, Page(s) 210

    Language German
    Document type Article
    ZDB-ID 2760403-2
    ISSN 2197-9707
    Database Current Contents Medicine

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  5. Article ; Online: DFP/CME: Melatonin – Stellenwert in der Pathophysiologie und Therapie der Demenz vom Alzheimertyp // Melatonin – importance in pathophysiologie and therapy of Alzheimer’s disease

    Seidel, S

    Journal für Neurologie, Neurochirurgie und Psychiatrie

    2019  Volume 20, Issue 2, Page(s) 58–62

    Abstract: Alzheimer’s disease (AD) is the most common form of dementia with an increasing prevalence in the general population. The personal and financial caregiver burden due to e.g. sleep-wake-rhythm disorders is remarkably high. Therefore the need for ... ...

    Abstract Alzheimer’s disease (AD) is the most common form of dementia with an increasing prevalence in the general population. The personal and financial caregiver burden due to e.g. sleep-wake-rhythm disorders is remarkably high. Therefore the need for preventive treatment options is high.brMelatonin is a pleiotropic neurohormon, secreted mainly by the pineal gland and known mainly for its chronobiotic properties. With increasing age the nocturnal peak level of melatonin decreases, leading to sleep fragmentation and disruption of the circadian sleep-wake cycle and potentially increasing the rising for cognitive decline in the elderly.brMelatonin and its metabolites also modulate multiple pathways which play important roles in the pathophysiology of AD (e.g. Aβ deposition, formation of neurofibrillary tangles). Clinical studies with patients with mild cognitive impairment or AD have shown improved sleep efficiency, mood and cognitive performance. Unfortunately, dosing of exogenous melatonin and assessment of relevant clinical parameters varies significantly between the studies and to date, prospective studies in healthy elderly patients are lacking. p bKurzfassung: /bDie Demenz vom Alzheimertyp (DAT) ist die häufigste Demenzform mit einer ansteigenden Prävalenz in der Allgemeinbevölkerung. Die persönliche und finanzielle Belastung der Betreuungspersonen („Caregiver“) ist u.a. durch die begleitenden Schlaf-Wach-Rhythmusstörungen hoch.brMelatonin ist ein pleiotropes Neurohormon, das großteils in der Glandula pinealis produziert wird und hauptsächlich für seine chronobiotischen Wirkungen bekannt ist. Mit steigendem Lebensalter kommt es zu einer Abnahme der nächtlichen maximalen Melatoninspiegel und dadurch zu einer vermehrten Schlaffragmentation und Störung des zirkadianen Schlaf-Wach-Rhythmus. Diese Veränderungen gehen bei älteren Menschen mit einem erhöhten Risiko für eine kognitive Einschränkung einher.brMelatonin und dessen Metaboliten modulieren mehrere Prozesse, die in der Pathophysiologie der DAT eine wesentliche Rolle spielen (Aβ-Ablagerung, Formierung von Neurofibrillenbündeln). Klinische Studien an Patienten mit „mild cognitive impairment“ oder DAT konnten unter Gabe von Melatonin eine Verbesserung der Schlafqualität, der Stimmung und der kognitiven Leistung zeigen. Leider variieren die verabreichten Melatonindosen und die Methodik zur Erhebung der einzelnen klinischen Parameter zwischen den verschiedenen Studien signifikant. Prospektive Studien zum Einsatz von Melatonin bei kognitiv gesunden älteren Patienten liegen derzeit nicht vor.
    MeSH term(s) Alzheimer, Demenz, Melatonin, Neurologie, Schlafstörung, dementia, sleep disorder
    Publishing date 20190628
    Document type Article ; Online
    ZDB-ID 2151261-9
    ISSN 1680-9440 ; 1608-1587
    ISSN (online) 1680-9440
    ISSN 1608-1587
    Database Krause and Pachernegg publications database

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    Zs.A 5924: Show issues Location:
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  6. Book ; Thesis: Chirurgische Therapie, prognostische Faktoren und Ergebnisse beim Lebertrauma

    Seidel, Susanne

    2006  

    Author's details eingereicht von: Susanne Seidel
    Language German
    Size 51, XII Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Leipzig, Univ., Diss., 2006
    HBZ-ID HT014971930
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2007 E 518 order for loan Magazin

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  7. Article ; Online: Propylene oxide derived glycol ethers: A review of the alkyl glycol ethers potential to cause endocrine disruption.

    Kelsey, Jeffrey R / Seidel, Shawn

    Regulatory toxicology and pharmacology : RTP

    2023  , Page(s) 105442

    Abstract: The 'propylene glycol ethers' (PGEs) are a group of chemical solvents and functional fluids produced through the reaction of propylene oxide (PO) and a monoalcohol. PGEs form different structural isomers, with possible permutations increasing with the ... ...

    Abstract The 'propylene glycol ethers' (PGEs) are a group of chemical solvents and functional fluids produced through the reaction of propylene oxide (PO) and a monoalcohol. PGEs form different structural isomers, with possible permutations increasing with the number of PO units in the molecule. The dominant isomers have only secondary hydroxyl groups and are not able to be metabolized to the acid structures that are associated with reproductive toxicity. There have been published claims that glycol ethers are human endocrine disruptors. This review systematically evaluates all the available and relevant in vitro and in vivo data across the propylene glycol ether family of substances using an approach based around the EFSA/ECHA 2018 guidance for the identification of endocrine disruptors. The conclusion reached is that there is no evidence to show that PGEs target any endocrine organs or perturb endocrine pathways.
    Language English
    Publishing date 2023-06-30
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 604672-1
    ISSN 1096-0295 ; 0273-2300
    ISSN (online) 1096-0295
    ISSN 0273-2300
    DOI 10.1016/j.yrtph.2023.105442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Correction to: 'TiDeTree: a Bayesian phylogenetic framework to estimate single-cell trees and population dynamic parameters from genetic lineage tracing data' (2022) by Seidel & Stadler.

    Seidel, Sophie / Stadler, Tanja

    Proceedings. Biological sciences

    2023  Volume 290, Issue 1990, Page(s) 20222312

    Language English
    Publishing date 2023-01-11
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 209242-6
    ISSN 1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
    ISSN (online) 1471-2954
    ISSN 0080-4649 ; 0962-8452 ; 0950-1193
    DOI 10.1098/rspb.2022.2312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1364: Show issues Location:
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  9. Article: Schlafstörungen

    Seidel, S.

    Neurologisch

    2018  Volume -, Issue 3, Page(s) 85

    Language German
    Document type Article
    ZDB-ID 2475252-6
    ISSN 2223-0629
    Database Current Contents Medicine

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  10. Article: Diagnostik und Therapie primärer ZNS-Lymphome

    Seidel, S. / Nilius-Eliliwi, V.

    Onkologie heute

    2022  Volume 21, Issue 12, Page(s) 8

    Language German
    Document type Article
    ZDB-ID 2147741-3
    ISSN 1612-006X
    Database Current Contents Medicine

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