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  1. Book ; Online ; E-Book: Drugs easily explained

    Seifert, Roland

    2022  

    Author's details Roland Seifert
    Keywords Pharmacology
    Subject code 405
    Language English
    Size 1 online resource (280 pages)
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9783031121883 ; 9783031121876 ; 3031121880 ; 3031121872
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Medikamente leicht erklärt

    Seifert, Roland

    2021  

    Author's details Roland Seifert
    Keywords Medicine  ; Health ; Arzneimittel;Arzneistoffe;Medikamente;Arzneistoffgruppen;Arznei;Behandlung;Arzneiwirkstoff ; Popular Science in Medicine and Health ; Health Sciences ; Medicine
    Language German
    Size 1 Online-Ressource (xv, 376 Seiten), Diagramme
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021585014
    ISBN 978-3-662-62330-5 ; 9783662623299 ; 3-662-62330-7 ; 3662623293
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Non-canonical cyclic nucleotides

    Seifert, Roland

    (Handbook of experimental pharmacology ; 238)

    2017  

    Author's details Roland Seifert editor
    Series title Handbook of experimental pharmacology ; 238
    Collection
    Keywords Nucleotides, Cyclic / pharmacology
    Language English
    Size 1 Online-Ressource (viii, 387 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019403669
    ISBN 978-3-319-52673-7 ; 9783319526713 ; 3-319-52673-1 ; 3319526715
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Thesis: Rolle der löslichen Adenylylzyklase in der Regulation zellulärer zyklischer Nukleosid-3',5'-monophosphate

    Hasan, Alan / Seifert, Roland

    2021  

    Institution Medizinische Hochschule Hannover
    Medizinische Hochschule Hannover / Institut für Pharmakologie
    Author's details vorgelegt von Alan Hasan ; aus dem Institut für Pharmakologie der Medizinischen Hochschule Hannover ; Betreuer/in der Arbeit: Prof. Dr. med. Roland Seifert
    Language German ; English
    Size III, 98 Blätter, Blatt IV-XIX, Blatt 236-240, Blatt XX-XXIII, Illustrationen, Diagramme
    Publishing place Hannover
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Medizinische Hochschule Hannover, 2022
    Note Text auf Deutsch, Sonderabdruck auf Englisch ; Enthält 1 Zeitschriftenaufsatz aus „Biochemical and Biophysical Research Communications", Jg. 448 (2014)
    HBZ-ID HT021694502
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 E 86 order for loan Magazin

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  5. Book: Basiswissen Pharmakologie

    Seifert, Roland

    (Springer Lehrbuch)

    2018  

    Author's details Roland Seifert
    Series title Springer Lehrbuch
    Keywords Arzneimittel ; Medikamente ; Medizinstudent ; Staatsexamen ; Prüfungsvorbereitung ; Klinischer Abschnitt ; Ärztliche Prüfung ; Transmitter ; Pharmaka ; Antiviral ; Mykologie ; Pharmakologie
    Subject Arzneimittellehre ; Arzneimittelwirkung ; Arzneiwirkung ; Experimentelle Pharmakologie
    Subject code 610
    Language German
    Size XXI, 494 Seiten, Illustrationen, Diagramme
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT019562605
    ISBN 978-3-662-56302-1 ; 3-662-56302-9 ; 9783662563038 ; 3662563037
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2018 A 1607 available for loan (reading room) Lesesaal EG

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  6. Book ; Online ; E-Book: Histamine and histamine receptors in health and disease

    Hattori, Yuichi / Seifert, Roland

    (Handbook of experimental pharmacology ; 241)

    2017  

    Author's details Yuichi Hattori, Roland Seifert editors
    Series title Handbook of experimental pharmacology ; 241
    Collection
    Keywords Histamine / physiology ; Receptors, Histamine / physiology ; Medicine ; Immunology ; Neurosciences ; Pharmacology ; Endocrinology ; Biochemistry
    Subject code 615
    Language English
    Size 1 Online-Ressource (viii, 363 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019659451
    ISBN 978-3-319-58194-1 ; 9783319581927 ; 3-319-58194-5 ; 3319581929
    DOI 10.1007/978-3-319-58194-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  7. Article ; Online: Prescriptions of homeopathic remedies at the expense of the German statutory health insurance from 1985 to 2021: scientific, legal and pharmacoeconomic analysis.

    Leemhuis, Hauke / Seifert, Roland

    Naunyn-Schmiedeberg's archives of pharmacology

    2024  

    Abstract: The prescription of homeopathic remedies at the expense of the statutory health insurance (SHI) system in Germany has been criticized for years due to a lack of evidence. Now, on the planned abolition of the reimbursement of homeopathic medicines in ... ...

    Abstract The prescription of homeopathic remedies at the expense of the statutory health insurance (SHI) system in Germany has been criticized for years due to a lack of evidence. Now, on the planned abolition of the reimbursement of homeopathic medicines in Germany, the debate on this topic has been reignited. The aim of this paper is to show the costs and their development over time incurred by homeopathic remedies in the healthcare system from 1985 to 2021. For this purpose, 15 selected homeopathic medicines were chosen from the drug prescription report (Arzneiverordnungsreport) and analyzed with regard to their development of DDD (Defined Daily Dose) using data from the Wissenschaftliches Institut der Ortskrankenkassen (WidO, Scientific Institute of the General Local Health Insurance Funds) and compared with their respective rational pharmacological alternatives. The price comparison was based on the DDD costs and the pharmacy retail price of the smallest packaging in each case. The clinical study situation for the preparations was also analyzed. For this purpose, the clinical studies provided by the manufacturer and those on PubMed were divided into evidence levels and analyzed. In addition, the presentation of homeopathic remedies on company websites, in online pharmacies, in specialist information and package leaflets was analyzed with regard to side effects, interactions, indication, and information on the alleged effect/proof of efficacy. In many media, information on homeopathic medicines remained incomplete, and non-compliance with the Therapeutic Product Advertising Act (Heilmittelwerbegesetz) was noted. Naming of the products if often very suggestive, too. Manufacturers' claims of efficacy go far beyond what can be considered proven in terms of evidence-based medicine and the quality of most clinical studies is poor. Homeopathic remedies are on average significantly more expensive than their rational pharmacological alternatives. Furthermore, DDD costs have continued to rise over the years analyzed. In aggregate, from a pharmacoeconomic, legal, and scientific perspective, abolition of reimbursement of homeopathic medicines in Germany at the expense of the SHI system is well justified.
    Language English
    Publishing date 2024-03-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 121471-8
    ISSN 1432-1912 ; 0028-1298
    ISSN (online) 1432-1912
    ISSN 0028-1298
    DOI 10.1007/s00210-024-03005-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.5: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: How Naunyn-Schmiedeberg's Archives of Pharmacology deals with fraudulent papers from paper mills.

    Seifert, Roland

    Naunyn-Schmiedeberg's archives of pharmacology

    2021  Volume 394, Issue 3, Page(s) 431–436

    Abstract: Fraudulent papers from paper mills are a serious threat to the entire scientific community. Naunyn-Schmiedeberg's Archives of Pharmacology has become the target of a massive attack of fraudulent papers originating from paper mills. This editorial ... ...

    Abstract Fraudulent papers from paper mills are a serious threat to the entire scientific community. Naunyn-Schmiedeberg's Archives of Pharmacology has become the target of a massive attack of fraudulent papers originating from paper mills. This editorial highlights 20 important features we observed with paper mills and explains how the journal is responding to this serious threat to restore the integrity of science. Hopefully, this editorial is also helpful for editors of other scientific journals.
    MeSH term(s) Biomedical Research/ethics ; Peer Review, Research/ethics ; Periodicals as Topic/standards ; Scientific Misconduct
    Language English
    Publishing date 2021-02-14
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 121471-8
    ISSN 1432-1912 ; 0028-1298
    ISSN (online) 1432-1912
    ISSN 0028-1298
    DOI 10.1007/s00210-021-02056-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.5: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Pharmacological articles in the German magazine DIE ZEIT (THE TIME)-content, adequacy, and comprehensibility.

    Böger, Laura Sophie / Seifert, Roland

    Naunyn-Schmiedeberg's archives of pharmacology

    2024  

    Abstract: The German weekly magazine DIE ZEIT (THE TIME) reaches more than one million readers per issue, mainly from high-income social classes. Pharmacological content is frequent in DIE ZEIT. As it therefore reaches many people who generally have no in-depth ... ...

    Abstract The German weekly magazine DIE ZEIT (THE TIME) reaches more than one million readers per issue, mainly from high-income social classes. Pharmacological content is frequent in DIE ZEIT. As it therefore reaches many people who generally have no in-depth knowledge of pharmacology, it can be assumed that DIE ZEIT is an important primary source of information. It should be its task to depict the drugs widely used by the population and to present them correctly and comprehensibly. This study analyzes 71 articles from 2012 to 2022 in terms of form, content, and comprehensibility. The analysis shows that in DIE ZEIT, drug groups largely correspond to the prescription figures and disease prevalence in Germany, with cardiovascular, neuropsychiatric, and pain medications being frequently discussed. There are deviations in the case of oncological drugs, for example, which are discussed more frequently than prescribed. New drug approvals are reported less frequently, and when they are, it is usually about the research phase. DIE ZEIT often reports on findings that are less than a week old and frequently quotes trustworthy experts, but no scientific sources can be found in around a quarter of the articles. A COVID-19 effect can also be identified in the years 2020 to 2022, as reporting on drugs for the treatment of coronavirus disease 2019 (COVID-19) predominated. An important point of criticism was identified with regard to comprehensibility. Less than half of the articles achieved the cut-off value for general comprehensibility specified by the Textlab analysis program, and only one article achieved the value for target group-oriented comprehensibility. This analysis confirms the problem that science communication is often too complicated and incomprehensible. It discusses the tension between the prescribed drugs and the mission of DIE ZEIT to entertain and should serve as a basis for analyzing other newspapers. Finally, we make specific suggestions how presentation of pharmacological topics in lay media can be improved in the future.
    Language English
    Publishing date 2024-03-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 121471-8
    ISSN 1432-1912 ; 0028-1298
    ISSN (online) 1432-1912
    ISSN 0028-1298
    DOI 10.1007/s00210-024-03053-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.5: Show issues Location:
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  10. Article ; Online: Vitamin A-containing dietary supplements from German and US online pharmacies: market and risk assessment.

    Rathmann, Anna-Miriam / Seifert, Roland

    Naunyn-Schmiedeberg's archives of pharmacology

    2024  

    Abstract: Vitamin A supplements are used by many people, and the number of newly registered dietary supplements is continuously increasing. The preparations fall under food law and are not subject to the strict controls of pharmaceuticals. Risk indications and ... ...

    Abstract Vitamin A supplements are used by many people, and the number of newly registered dietary supplements is continuously increasing. The preparations fall under food law and are not subject to the strict controls of pharmaceuticals. Risk indications and maximum quantity recommendations, e.g., from the Bundesinstitut für Risikobewertung (BfR) and the U.S. Food and Drug Administration (FDA) are not binding, which means that overdoses and potentially serious health problems can easily occur. The hepatotoxicity and teratogenicity of vitamin A are well documented, and other negative effects of high doses of vitamin A are also being discussed. Nevertheless, preparations with exorbitantly high doses are freely available for sale and unrestricted. In this study, 75 supplements containing vitamin A available in Germany and 26 available in the USA were critically examined on the basis of various parameters such as the recommended daily dose according to the manufacturer, daily therapy costs (DTC), the presence of warnings about overdose, use during pregnancy and breastfeeding, and information on adverse effects/interactions. The aim was to gain insights into their risk potential and to examine the need for closer monitoring and stricter guidelines for these preparations. The results show some considerable country-specific differences. Overall, there are serious deficiencies in compliance with the labeling requirements for both the German and the US preparations, and the dosages are often far too high in view of the applicable expert recommendations. Overall, these deficits can pose a risk for consumers that is difficult to assess in its entirety, especially for vulnerable consumer groups. It should be noted that the US preparations perform better overall than the German preparations. This suggests better regulation of dietary supplements in the US market. Based on the available data and literature research, it is doubtful whether the intake of vitamin A-containing preparations, without a diagnosed vitamin A deficiency, has a positive health benefit. Furthermore, it should be examined whether vitamin A should continue to be offered over-the-counter as a food supplement.
    Language English
    Publishing date 2024-03-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 121471-8
    ISSN 1432-1912 ; 0028-1298
    ISSN (online) 1432-1912
    ISSN 0028-1298
    DOI 10.1007/s00210-024-03050-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.5: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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