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  1. AU="Seiler, Joclyn"
  2. AU="de Cesare, Niccolò"
  3. AU="Agrawal, Rohit Vijay"
  4. AU="Nakae, Mami"
  5. AU="Blake, Christine E"
  6. AU=Pareek Anil
  7. AU="Shokrollahi, Mitra"
  8. AU="Charles?Luce"
  9. AU="Denadai, Rafael"
  10. AU="Ambrosino, Teresa"
  11. AU=Antipova Tatiana
  12. AU="Moens, Pierre D J"
  13. AU="Abdel-Megied, Ahmed M."
  14. AU="Jain, Aseem"
  15. AU="Marcos, Jose F"
  16. AU="Furr-Stimming, Erin"
  17. AU="Schüle, Birgit"
  18. AU="Travieso-González, Alejandro"
  19. AU=Turilli Emily Samuela
  20. AU="Rueckert, Erroll H"
  21. AU=Keestra-Gounder A. Marijke
  22. AU="María José Endara"
  23. AU="Li, Lin-Zi"
  24. AU="Shirvanian, Moein"
  25. AU="Capaldo, Bianca D"
  26. AU="Matose, Takunda"
  27. AU=Plouffe Brian D.
  28. AU=Kuter David J
  29. AU="Moore, I D"
  30. AU="Schreibing, Felix"
  31. AU=Kang Keunsoo
  32. AU="de Pedro-Múñez, Álvaro"

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  1. Artikel ; Online: A Case of Argatroban Refractory Heparin Induced Thrombocytopenia and Thrombosis.

    Seiler, Joclyn A / Durrani, Adam Khan / Ahmeti, Mentor

    The American surgeon

    2023  Band 89, Heft 8, Seite(n) 3574–3575

    Abstract: Prophylaxis for deep vein thrombosis is a standard of care for most hospitalized patients. This is typically given in the form of chemical prophylaxis by either, unfractionated heparin or low molecular weight heparin. One complication of administration, ... ...

    Abstract Prophylaxis for deep vein thrombosis is a standard of care for most hospitalized patients. This is typically given in the form of chemical prophylaxis by either, unfractionated heparin or low molecular weight heparin. One complication of administration, besides bleeding, is heparin induced thrombocytopenia (HIT). Of patients receiving therapeutic anticoagulation with heparin an estimated, .5%-1% will go on to develop heparin induced thrombocytopenia.
    Mesh-Begriff(e) Humans ; Heparin/therapeutic use ; Anticoagulants/adverse effects ; Thrombocytopenia/chemically induced ; Thrombocytopenia/drug therapy ; Thrombosis/chemically induced ; Thrombosis/drug therapy
    Chemische Substanzen Heparin (9005-49-6) ; Anticoagulants ; argatroban (IY90U61Z3S)
    Sprache Englisch
    Erscheinungsdatum 2023-03-15
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348231161690
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Laparoscopic-Assisted Transversus Abdominis Plane Block Is Superior to Port Site Infiltration in Reducing Post-Operative Opioid Use in Laparoscopic Surgery.

    Seiler, Joclyn / Chong, Alexander Cm / Chen, Sugong

    The American surgeon

    2022  Band 88, Heft 9, Seite(n) 2094–2099

    Abstract: Background: The ultrasound-guided transversus abdominis plane (TAP) block can be time-consuming, costly, and technically challenging in the bariatric patient population. Laparoscopic-assisted TAP (L-TAP) block was developed and has been shown to be non- ... ...

    Abstract Background: The ultrasound-guided transversus abdominis plane (TAP) block can be time-consuming, costly, and technically challenging in the bariatric patient population. Laparoscopic-assisted TAP (L-TAP) block was developed and has been shown to be non-inferior to ultrasound-guided blocks. Postoperative pain can be significant, and pain control in the morbidly obese patients can be challenging. This study's aim was to compare L-TAP block to traditional port site infiltration in terms of postoperative opioid requirement for morbidly obese patients after laparoscopic Roux-en-Y gastric bypass (RYGB) surgery.
    Methods: A retrospective chart review was performed from February 2019 through February 2020. Two study groups: L-TAP block and port site infiltration. Outcomes examined the amount of opioid used at different time segments relative to the operation. All intravenous (IV) and oral opioids used were converted into IV morphine milligram equivalents (MME) for standardization.
    Results: 150 patients were included. The patient characteristics were not statistically significant between the two groups. Post-operative opioid use trended lower in the L-TAP block group in all time segments. A significant difference was detected in IV opioid use during post-operative day 0 with the mean MME for the L-TAP block group being 1.1±3.8 and port site infiltration group being 2.8±4.5 (P = .02)
    Conclusions: The L-TAP block more effectively reduces postoperative opioid use in comparison to port site infiltration in laparoscopic Roux-en-Y gastric bypass (RYGB) surgery. Based on these findings, as well as the efficiency and cost-effectiveness of L-TAP blocks, its routine use in laparoscopy should be considered.
    Mesh-Begriff(e) Abdominal Muscles ; Analgesics, Opioid/therapeutic use ; Anesthetics, Local ; Endrin/analogs & derivatives ; Humans ; Laparoscopy ; Morphine Derivatives ; Obesity, Morbid/surgery ; Opioid-Related Disorders ; Pain, Postoperative/drug therapy ; Pain, Postoperative/prevention & control ; Pain, Postoperative/surgery ; Retrospective Studies
    Chemische Substanzen Analgesics, Opioid ; Anesthetics, Local ; Morphine Derivatives ; MME (78185-58-7) ; Endrin (OB9NVE7YCL)
    Sprache Englisch
    Erscheinungsdatum 2022-04-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348221087923
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Longitudinal Effects of Embryonic Exposure to Cocaine on Morphology, Cardiovascular Physiology, and Behavior in Zebrafish.

    Mersereau, Eric J / Boyle, Cody A / Poitra, Shelby / Espinoza, Ana / Seiler, Joclyn / Longie, Robert / Delvo, Lisa / Szarkowski, Megan / Maliske, Joshua / Chalmers, Sarah / Darland, Diane C / Darland, Tristan

    International journal of molecular sciences

    2016  Band 17, Heft 6

    Abstract: A sizeable portion of the societal drain from cocaine abuse results from the complications of in utero drug exposure. Because of challenges in using humans and mammalian model organisms as test subjects, much debate remains about the impact of in utero ... ...

    Abstract A sizeable portion of the societal drain from cocaine abuse results from the complications of in utero drug exposure. Because of challenges in using humans and mammalian model organisms as test subjects, much debate remains about the impact of in utero cocaine exposure. Zebrafish offer a number of advantages as a model in longitudinal toxicology studies and are quite sensitive physiologically and behaviorally to cocaine. In this study, we have used zebrafish to model the effects of embryonic pre-exposure to cocaine on development and on subsequent cardiovascular physiology and cocaine-induced conditioned place preference (CPP) in longitudinal adults. Larval fish showed a progressive decrease in telencephalic size with increased doses of cocaine. These treated larvae also showed a dose dependent response in heart rate that persisted 24 h after drug cessation. Embryonic cocaine exposure had little effect on overall health of longitudinal adults, but subtle changes in cardiovascular physiology were seen including decreased sensitivity to isoproterenol and increased sensitivity to cocaine. These longitudinal adult fish also showed an embryonic dose-dependent change in CPP behavior, suggesting an increased sensitivity. These studies clearly show that pre-exposure during embryonic development affects subsequent cocaine sensitivity in longitudinal adults.
    Mesh-Begriff(e) Animals ; Behavior, Animal/drug effects ; Cardiovascular Physiological Phenomena/drug effects ; Cocaine/toxicity ; Dose-Response Relationship, Drug ; Embryo, Nonmammalian/drug effects ; Zebrafish/embryology
    Chemische Substanzen Cocaine (I5Y540LHVR)
    Sprache Englisch
    Erscheinungsdatum 2016-05-31
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms17060847
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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