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Article ; Online: La rétention trophoblastique hypervascularisée peut-elle être considérée comme une malformation vasculaire acquise ?

Zenati, Nora / Seinturier, Christophe / Blaise, Sophie

Gynecologie, obstetrique, fertilite & senologie

2023 Volume 51, Issue 7-8, Page(s) 387–389

Title translation	Can retained products of conception be considered as an unclassified acquired vascular malformation?
MeSH term(s)	Humans ; Female ; Uterus ; Fertilization ; Vascular Diseases ; Vascular Malformations ; Retrospective Studies
Language	French
Publishing date	2023-03-15
Publishing country	France
Document type	Letter
ZDB-ID	2887456-0
ISSN	2468-7189
ISSN (online)	2468-7189
DOI	10.1016/j.gofs.2023.03.006
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Article: Negative pressure wound therapy with instillation and dwell time in debridement of fibrinous leg ulcers.

Achiti, Alexandru / Zenati, Nora / Seinturier, Christophe / Cracowski, Jean-Luc / Blaise, Sophie

Journal of wound care

2024 Volume 33, Issue 3, Page(s) 166–170

Abstract: Objective: In conjunction with appropriate wound care, negative pressure wound therapy with instillation and dwell time (NPWTi-d) may be used as an adjunct therapy for acute or hard-to-heal (chronic) wounds, especially when infected. However, there are ... ...

Abstract	Objective: In conjunction with appropriate wound care, negative pressure wound therapy with instillation and dwell time (NPWTi-d) may be used as an adjunct therapy for acute or hard-to-heal (chronic) wounds, especially when infected. However, there are very few data on the use of NPWTi-d in the treatment of fibrinous wounds that are difficult to debride mechanically. The main objective of this study was to describe changes in the fibrin area of such wounds, before and after treatment with NPWTi-d. Method: This was a monocentric, observational, prospective pilot study evaluating the NPWTi-d medical device. Eligible patients included in the study were those with hard-to-heal lower limb ulcers who had previously undergone unsuccessful specific debridement treatment for their wound, with failure of manual mechanic debridement for at least six weeks' duration, and whose wounds had a fibrinous surface area of >70% of the total wound surface area. The primary endpoint was the difference in the percentage of fibrinous surface area before and after treatment. Results: A total of 14 patients who received treatment for lower limb ulcers between October 2017 and August 2019 were included in the study. There was a significant shrinkage rate of the fibrinous wound surface between the start and end of treatment (83.6±14.5% and 32.2±19.7%, respectively; p<0.001). Conclusion: This study showed a significant decrease in fibrin area in wounds treated with NPWTi-d, with good tolerance. We believe that NPWTi-d has its place in the multidisciplinary management of patients with hard-to-heal ulcers. Additional randomised studies are required to confirm these findings. Declaration of interest: The authors have no conflicts of interest.
MeSH term(s)	Humans ; Debridement ; Wound Infection/therapy ; Negative-Pressure Wound Therapy ; Ulcer ; Pilot Projects ; Prospective Studies ; Leg Ulcer/therapy ; Fibrin ; Therapeutic Irrigation
Chemical Substances	Fibrin (9001-31-4)
Language	English
Publishing date	2024-03-11
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	1353951-6
ISSN	0969-0700
ISSN	0969-0700
DOI	10.12968/jowc.2024.33.3.166
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Zs.A 4572: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Localised intravascular coagulation complicating venous malformations: Clinical characterisation.

Blaise, Sophie / Soya, Esaie / Nou, Monira / Malloizel-Delaunay, Julie / Thiel, Hélène / Bisdorff-Bresson, Annouk / Seinturier, Christophe

Phlebology

2023 Volume 39, Issue 3, Page(s) 169–173

Abstract: Objective: The International Union of Phlebology recommends measuring at least D-dimer and fibrinogen levels in the diagnosis of extensive extra-truncular venous malformations, with a surface area of 10 cm: Method: This study was an observational and ...

Abstract	Objective: The International Union of Phlebology recommends measuring at least D-dimer and fibrinogen levels in the diagnosis of extensive extra-truncular venous malformations, with a surface area of 10 cm Method: This study was an observational and multicentre study. The objective was to explore the presence of a possible coagulation disorder among patients with venous malformation. The primary endpoint was to characterise venous malformations with increased D-dimer levels. Results: The majority of the 72 venous malformations were located in the trunk region, mostly in intramuscular or subcutaneous locations. There were 72 venous malformations with increased D-dimer levels including 3 with biological disseminated intravascular coagulation (elevated D-dimer and fibrinogen <1 g/L). The anticoagulant treatments administered were very heterogeneous in class and dosage, and at the end of the treatment, 17 elevated D-dimers were persistent, 9 venous malformations remained painful and 27 showed thrombotic regression. Conclusion: Venous vascular malformations are probably underestimated and should probably be explored more systematically in terms of coagulation disorder regardless of size or symptomatology. The therapeutic recommendations to treat localised intravascular coagulation with low-molecular weight are not widely applied. Studies are needed, in particular to assess the role of oral anticoagulants in the management of coagulation disorder among patients with venous malformation.
MeSH term(s)	Humans ; Anticoagulants/therapeutic use ; Vascular Malformations/diagnosis ; Blood Coagulation Disorders ; Veins/abnormalities ; Fibrinogen/therapeutic use ; Fibrin Fibrinogen Degradation Products
Chemical Substances	Anticoagulants ; Fibrinogen (9001-32-5) ; Fibrin Fibrinogen Degradation Products
Language	English
Publishing date	2023-11-18
Publishing country	England
Document type	Observational Study ; Multicenter Study ; Journal Article
ZDB-ID	645172-x
ISSN	1758-1125 ; 0268-3555
ISSN (online)	1758-1125
ISSN	0268-3555
DOI	10.1177/02683555231216349
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Article ; Online: Digital pressure with laser Doppler flowmetry is better than photoplethysmography to characterize peripheral arterial disease of the upper limbs in end-stage renal disease patients.

Briche, Nicolas / Seinturier, Christophe / Cracowski, Jean Luc / Zaoui, Philippe / Blaise, Sophie

Microvascular research

2021 Volume 139, Page(s) 104264

Abstract: Objective: There is no consensual definition of significant peripheral arterial disease of the upper limbs. Patients with end-stage renal disease are usually explored with Doppler ultrasound, which seems insufficient to characterize and quantify the ... ...

Abstract	Objective: There is no consensual definition of significant peripheral arterial disease of the upper limbs. Patients with end-stage renal disease are usually explored with Doppler ultrasound, which seems insufficient to characterize and quantify the arterial disease in this anatomic site. Candidates for haemodialysis access tend to be increasingly older and have polyvascular disease, and a better assessment of the vascular status of their upper limbs with finger systolic blood pressure is necessary. Photoplethysmography is simple and currently used in practice, but laser Doppler flowmetry may be more sensitive for low values. Our objective is to investigate additional information in the digit assessment over the ultrasound assessment of the upper limbs of patients awaiting haemodialysis and compare digital pressure values taken by photoplethysmography and laser Doppler. Methods: All included patients with end-stage renal disease scheduled for haemodialysis access received a prospective evaluation of their upper limbs with a clinical examination of the hands, an arterial upper limb Doppler ultrasound, and finger systolic blood pressure using photoplethysmography and laser Doppler flowmetry. Significant upper limb arterial disease was defined by a finger systolic blood pressure below 60 mm Hg or a finger brachial pressure index below 0.7. Results: Twenty-four patients were included in the study. In all, 41.7% of patients (n = 10) had parietal calcifications to the antebrachial arteries on Doppler ultrasound, 8.3% of patients (n = 2) had bilateral finger systolic blood pressure values below 60 mm Hg with laser Doppler flowmetry (but not confirmed with photoplethysmography), and 16.6% of patients (n = 4) had a finger brachial pressure index below 0.7 on both laser Doppler flowmetry and photoplethysmography. While there was an agreement between these two methods, higher values were recorded with photoplethysmography. The Pearson coefficient was 0.493 for the median of basal digital pressures in absolute values and 0.489 for finger brachial pressure index (p < 0.001). Conclusion: Our study confirms the need to evaluate significant upper limb arterial disease in patients with end-stage renal disease not only with Doppler ultrasound but also with an evaluation of the finger systolic blood pressure. The correlation of the finger systolic blood pressure values using laser Doppler flowmetry and photoplethysmography was poor, which was probably due to an overestimation of the pressures with photoplethysmography. Despite the absence of a gold standard, we suggest that Laser Doppler flowmetry should be used rather than photoplethysmography to better characterize significant peripheral arterial disease of the upper limbs in patients with end-stage renal disease, particularly before creation of a new haemodialysis access. Protocol Record on clinical trial 38RC19.285.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Arterial Pressure ; Blood Pressure Determination/methods ; Female ; Fingers/blood supply ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/physiopathology ; Kidney Failure, Chronic/therapy ; Laser-Doppler Flowmetry ; Male ; Middle Aged ; Peripheral Arterial Disease/complications ; Peripheral Arterial Disease/diagnosis ; Peripheral Arterial Disease/physiopathology ; Photoplethysmography ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Regional Blood Flow ; Renal Dialysis ; Ultrasonography, Doppler
Language	English
Publishing date	2021-10-12
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	80307-8
ISSN	1095-9319 ; 0026-2862
ISSN (online)	1095-9319
ISSN	0026-2862
DOI	10.1016/j.mvr.2021.104264
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Article ; Online: Prevalence and severity of peripheral arterial disease among patient with heel pressure ulcer: a retrospective study of 42 patients.

Tisserand, Guillaume / Zenati, Nora / Seinturier, Christophe / Blaise, Sophie / Pernod, Gilles

Geriatrie et psychologie neuropsychiatrie du vieillissement

2017 Volume 15, Issue 3, Page(s) 242–246

Abstract: Heel pressure ulcer is a major complication in elderly hospitalized patients. The association with peripheral arterial disease (PAD) which is also a frequent disease in this population is poorly known. The aim of this study was to assess the prevalence ... ...

Title translation	Prévalence et sévérité de l’artériopathie oblitérante des membres inférieurs chez les patients atteints d’escarre talonnière : étude rétrospective de 42 patients.
Abstract	Heel pressure ulcer is a major complication in elderly hospitalized patients. The association with peripheral arterial disease (PAD) which is also a frequent disease in this population is poorly known. The aim of this study was to assess the prevalence of PAD and critical limb ischemia (CLI) in patients with heel pressure ulcer. Patients referred to the vascular medicine department for heel pressure ulcer from October 2014 to June 2015 were included in the study. The assessment of peripheral arterial disease was made with the results of ankle brachial index and/or doppler ultra sound of lower limb arteries. Toe systolic pressure and transcutaneous pressure (TcPO2) were also recorded, and the diagnosis of critical limb ischemia was made according to the TASC 2 criteria. The population was composed with 42 patients (women 43%, men 57%). The mean age was 81±11 years. Heel pressures ulcers were diagnosed in the following situations: lower limb fracture (31%), acute medical illness (21%), multiple chronic conditions (28%) and critical care unit hospitalization (7%). A peripheral arterial disease was present in 31 patients (73%), and a critical limb ischemia in 7 patients. For 18 patients, PAD was not known in their past medical history, and this was the case of 5 patients among those with critical limb ischemia. A revascularization was performed in 12 patients, and 5 patients undergo a lower limb amputation. 12 patients were died at 3 months. PAD is frequent among patients with heel pressure ulcer, and is often unknown. The functional and vital prognostic are poor, and the results of our study emphasize the importance of screening PAD in the evaluation of heel pressure ulcer risk.
Language	English
Publishing date	2017-09-01
Publishing country	France
Document type	Journal Article
ISSN	2115-7863
ISSN (online)	2115-7863
DOI	10.1684/pnv.2017.0680
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Article: Fluorescence angiography compared to toe blood pressure in the evaluation of severe limb ischemia.

Seinturier, Christophe / Blaise, Sophie / Tiffet, Théophile / Provencher, Cynthia Brousseau / Cracowski, Jean Luc / Pernod, Gilles / Carpentier, Patrick

VASA. Zeitschrift fur Gefasskrankheiten

2020 Volume 49, Issue 3, Page(s) 230–234

MeSH term(s)	Blood Gas Monitoring, Transcutaneous ; Blood Pressure ; Cross-Sectional Studies ; Fluorescein Angiography ; Humans ; Ischemia ; Toes
Language	English
Publishing date	2020-02-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	120977-2
ISSN	1664-2872 ; 0301-1526
ISSN (online)	1664-2872
ISSN	0301-1526
DOI	10.1024/0301-1526/a000853
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Article ; Online: A Femoral Common Vein Aneurysm in a Patient with Neurofibromatosis Syndrome Type 1.

Seinturier, Christophe / Blaise, Sophie / Thony, Frédéric / Magne, Jean Luc / Pernod, Gilles

Annals of vascular surgery

2017 Volume 40, Page(s) 299.e7–299.e9

Abstract: Neurofibromatosis type I (NFI), also called Von Recklinghausen disease, is an autosomal dominant disease secondary to a genetic mutation on the long arm of chromosome 17. This disorder affects neural crest cells. Cutaneous clinical forms are the most ... ...

Abstract	Neurofibromatosis type I (NFI), also called Von Recklinghausen disease, is an autosomal dominant disease secondary to a genetic mutation on the long arm of chromosome 17. This disorder affects neural crest cells. Cutaneous clinical forms are the most frequent with multiple benign skin neurofibromas, associated with café au lait skin spots and iris hamartomas. Vascular abnormalities in NF1 are rare but have also been well described. The most frequent abnormalities are characterized by arterial aneurysm degeneration, stenosis, and malformations. Venous locations are rare, but some cases of venous aneurysms were described with ruptures as complications. We present a rare case of thrombosed venous femoral aneurysm associated with a pulmonary embolism in a patient affected by NF1.
MeSH term(s)	Aneurysm/diagnostic imaging ; Aneurysm/etiology ; Aneurysm/surgery ; Computed Tomography Angiography ; Female ; Femoral Vein/diagnostic imaging ; Femoral Vein/surgery ; Humans ; Middle Aged ; Neurofibromatosis 1/complications ; Neurofibromatosis 1/diagnosis ; Phlebography/methods ; Pulmonary Embolism/etiology ; Treatment Outcome ; Venous Thrombosis/etiology
Language	English
Publishing date	2017-04
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	1027366-9
ISSN	1615-5947 ; 0890-5096
ISSN (online)	1615-5947
ISSN	0890-5096
DOI	10.1016/j.avsg.2016.08.039
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Article: Paroxysmal finger haematoma--a benign acrosyndrome occurring in middle-aged women.

Carpentier, Patrick H / Maricq, Hildegard R / Biro, Christine / Jiguet, Myriam / Seinturier, Christophe

VASA. Zeitschrift fur Gefasskrankheiten

2016 Volume 45, Issue 1, Page(s) 57–62

Abstract: Background: Paroxysmal finger haematoma (PFH) is an under-recognised vascular acrosyndrome with no epidemiological description to date. The aim of this work was to evaluate the prevalence, risk factors and clinical correlates of PFH in a population- ... ...

Abstract	Background: Paroxysmal finger haematoma (PFH) is an under-recognised vascular acrosyndrome with no epidemiological description to date. The aim of this work was to evaluate the prevalence, risk factors and clinical correlates of PFH in a population-based sample of subjects and to describe their semiological characteristics. Patients and methods: This cross-sectional study of random samples of the general population in three geographic areas of France involved 802 subjects, 548 women and 254 men, aged 18 to 84 years. The diagnosis of PFH was made from a report by the subject of a history of recurrent haematoma in the fingers with a sudden, painful and unexpected occurrence. Diagnosis of associated conditions and evaluation of lifestyle variables were obtained through standardised medical interview and examination. Results: A history of PFH was detected in 71 subjects, with a prevalence of 1.2% in men and 12.4% in women; there was no significant regional variation. Onset before 40 years of age was rare. Besides female sex and age, no socio-economical nor lifestyle risk factors were detected. PFH was associated with Raynaud phenomenon and a history of chilblains, but no link with any health threatening disease was found. In addition to the sudden onset of pain and hematoma, the main clinical features were a frequent digital swelling during the painful attack, and their predominant location on the volar side of the first and second phalanges of the third or second fingers of the dominant hand. Conclusions: PFH is a benign phenomenon, frequently found in middle-aged women, to be classified among the vascular acrosyndromes. Patients seeking medical evaluation for this disorder should be reassured.
MeSH term(s)	Adolescent ; Adult ; Age Distribution ; Age Factors ; Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Female ; Fingers/blood supply ; France/epidemiology ; Hematoma/diagnosis ; Hematoma/epidemiology ; Humans ; Male ; Middle Aged ; Prevalence ; Raynaud Disease/diagnosis ; Raynaud Disease/epidemiology ; Recurrence ; Risk Assessment ; Risk Factors ; Sex Distribution ; Sex Factors ; Young Adult
Language	English
Publishing date	2016-01
Publishing country	Switzerland
Document type	Journal Article ; Multicenter Study
ZDB-ID	120977-2
ISSN	1664-2872 ; 0301-1526
ISSN (online)	1664-2872
ISSN	0301-1526
DOI	10.1024/0301-1526/a000496
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Article ; Online: Recanalization and stenting of a post-thrombotic iliac vein in a patient with Behçet's disease.

Seinturier, Christophe / Thony, Frédéric / Blaise, Sophie / Pernod, Gilles / Carpentier, Patrick Henri

Journal of vascular surgery. Venous and lymphatic disorders

2014 Volume 2, Issue 3, Page(s) 324–326

Abstract: Vascular lesions are frequent in Behçet's disease, and among them, deep venous thrombosis may occur in up to one-third of patients. Treatment is based on immunosuppressive drugs in addition to anticoagulants. We report the case of a young woman who ... ...

Abstract	Vascular lesions are frequent in Behçet's disease, and among them, deep venous thrombosis may occur in up to one-third of patients. Treatment is based on immunosuppressive drugs in addition to anticoagulants. We report the case of a young woman who presented with an acute iliofemoral venous thrombosis. Acute treatment with endovascular thrombectomy and catheter-directed fibrinolysis failed, probably because of the inflammatory status of the vessel wall. Recanalization with stenting of the obstructed common femoral and iliac veins 1 year later was successful under immunosuppressive therapy. This case suggests that endovascular treatment of venous thrombosis in Behçet's disease may be conducted successfully in nonactive venous lesions under immunosuppressive therapy.
Language	English
Publishing date	2014-07
Publishing country	United States
Document type	Journal Article
ISSN	2213-3348
ISSN (online)	2213-3348
DOI	10.1016/j.jvsv.2013.11.002
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Article ; Online: Endovascular Treatment of Post-thrombotic Venous Ilio-Femoral Occlusions: Prognostic Value of Venous Lesions Caudal to the Common Femoral Vein.

Menez, Caroline / Rodiere, Mathieu / Ghelfi, Julien / Seinturier, Christophe / Martinelli, Thomas / Imbert, Bernard / Perolat, Romain / Bouzat, Pierre / Blaise, Sophie / Carpentier, Patrick / Pernod, Gilles / Thony, Frédéric

Cardiovascular and interventional radiology

2019 Volume 42, Issue 8, Page(s) 1117–1127

Abstract: Objectives: To propose a scale of severity for post-thrombotic venous lesions (PTVLs) after ilio-femoral deep venous thrombosis and to compare the grade with the results of endovascular treatment of ilio-femoral PTVLs.: Methods: In this retrospective ...

Abstract	Objectives: To propose a scale of severity for post-thrombotic venous lesions (PTVLs) after ilio-femoral deep venous thrombosis and to compare the grade with the results of endovascular treatment of ilio-femoral PTVLs. Methods: In this retrospective monocentric observational study, we included 95 patients treated for ilio-femoral PTVLs. We proposed a four-grade scale evaluating the severity of PTVLS caudal to the common femoral vein based on CT phlebography and per-operative phlebography. For most patients, venous patency was assessed with color duplex ultrasonography and the clinical efficacy of the intervention using the Villalta and CIVIQ scores. Results: Recanalization was successful in 100% of patients with a morbidity rate of 4%. After a mean follow-up of 21 months, the overall primary patency was 75%, the assisted primary patency 82%, and the secondary patency 93%. Secondary patency was 100% for grade 0-1, 90% for grade 2, and 63% for grade 3 (p < 0.002). There was no correlation between the extension of stenting caudally of the common femoral vein and venous patency. The mean improvements in the Villalta and CIVIQ-20 scores were, respectively, 4.6 (p < 0.0001) and 18 (p < 0.0001); scores were not correlated with the grade of PTVLs in the thigh. Conclusion: Venous patency after endovascular treatment of ilio-femoral PTVLs was strongly linked to the severity of PTVLs caudal to the common femoral vein but not to the extent of stenting.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Arterial Occlusive Diseases/complications ; Arterial Occlusive Diseases/diagnostic imaging ; Arterial Occlusive Diseases/surgery ; Endovascular Procedures/methods ; Female ; Femoral Vein/diagnostic imaging ; Femoral Vein/surgery ; Humans ; Iliac Vein/diagnostic imaging ; Iliac Vein/surgery ; Male ; Middle Aged ; Postthrombotic Syndrome/complications ; Postthrombotic Syndrome/surgery ; Prognosis ; Retrospective Studies ; Treatment Outcome ; Ultrasonography, Doppler, Color ; Young Adult
Keywords	covid19
Language	English
Publishing date	2019-05-06
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	603082-8
ISSN	1432-086X ; 0342-7196 ; 0174-1551
ISSN (online)	1432-086X
ISSN	0342-7196 ; 0174-1551
DOI	10.1007/s00270-019-02214-9
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