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  1. Article ; Conference proceedings: Abstracts / International Symposium Advances in Transfusion Safety 2001

    Seitz, Rainer

    June 7 to 8, 2001, Paul-Ehrlich-Institut, Langen, Germany ; under the patronage of the German Federal Minister of Health

    2001  

    Title variant Advances in transfusion safety 2001
    Institution Paul-Ehrlich-Institut
    Event/congress International Symposium Advances in Transfusion Safety (2001, LangenHessen)
    Author's details guest ed.: Rainer Seitz
    Language English
    Publishing country Germany
    Document type Article ; Conference proceedings
    Note In: Infusion therapy and transfusion medicine. - ISSN 1424-5485. - 28 (2001),4, S. 228 - 247
    HBZ-ID HT013136912
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Wie lassen sich Anti-Drug-Antikörper verhindern? EU-Forschungskonsortium mit Beteiligung des PEI

    Waibler, Zoe / Seitz, Rainer

    Bulletin zur Arzneimittelsicherheit, 2012(3):36-38

    2012  

    Abstract: Antikörper gegen Medikamente – sogenannte Anti-Drug-Antikörper – sind bei der Behandlung mit biologischen Arzneimitteln eine gefürchtete Komplikation. Bekannt ist das Auftreten solcher Antikörper beispielsweise bei der Behandlung von Patienten mit ... ...

    Institution Paul-Ehrlich-Institut
    Abstract Antikörper gegen Medikamente – sogenannte Anti-Drug-Antikörper – sind bei der Behandlung mit biologischen Arzneimitteln eine gefürchtete Komplikation. Bekannt ist das Auftreten solcher Antikörper beispielsweise bei der Behandlung von Patienten mit Hämophilie A (Faktor-VIII-Mangel), bei der Interferonbehandlung sowie bei der Behandlung mit monoklonalen Antikörpern. Im Forschungskonsortium ABIRISK – „Anti-Biopharmaceutical Immunization: Prediction and analysis of clinical relevance to minimize the RISK“ – wird die klinische Relevanz solcher Antikörper gegen biologische Arzneimittel untersucht und nach Möglichkeiten der Risikominimierung gesucht. Das Paul-Ehrlich-Institut (PEI) ist einer von insgesamt 37 europäischen Kooperationspartnern des von der „Innovative Medicines Initiative“ (IMI)1 geförderten Forschungskonsortiums. Im Folgenden werden das Forschungsprojekt und die Fragestellungen, die vom PEI bearbeitet werden, kurz vorgestellt.
    Keywords Antikörper ; Arzneimittelnebenwirkung
    Language German
    Document type Article
    DOI 10.4126/FRL01-006412557
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  3. Article ; Online: "Thromboinflammation in COVID-19: can α2-macroglobulin help to control the fire?": Comment from Seitz et al.

    Seitz, Rainer / Gürtler, Lutz / Schramm, Wolfgang

    Journal of thrombosis and haemostasis : JTH

    2023  Volume 21, Issue 3, Page(s) 704–705

    MeSH term(s) Humans ; Pregnancy ; Female ; Pregnancy-Associated alpha 2-Macroglobulins ; Thromboinflammation ; COVID-19 ; Inflammation ; Thrombosis ; Enzyme Inhibitors ; Transcription Factors
    Chemical Substances Pregnancy-Associated alpha 2-Macroglobulins ; Enzyme Inhibitors ; Transcription Factors
    Language English
    Publishing date 2023-03-01
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1016/j.jtha.2023.01.005
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  4. Article: Too Early to Abandon Convalescent Plasma for Supportive Treatment of COVID-19.

    Seitz, Rainer / Gürtler, Lutz / Vahlensieck, Ute / Hilger, Anneliese / Schramm, Wolfgang

    Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

    2023  Volume 50, Issue 3, Page(s) 256–258

    Language English
    Publishing date 2023-04-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2100848-6
    ISSN 1660-3818 ; 1660-3796
    ISSN (online) 1660-3818
    ISSN 1660-3796
    DOI 10.1159/000530097
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  5. Article ; Online: DIC in COVID-19: Implications for prognosis and treatment?

    Seitz, Rainer / Schramm, Wolfgang

    Journal of thrombosis and haemostasis : JTH

    2020  Volume 18, Issue 7, Page(s) 1798–1799

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Prognosis ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-14
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.14878
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  6. Article ; Online: Cerebral venous thrombosis after COVID-19 vaccination: is the risk of thrombosis increased by intravascular application of the vaccine?

    Gürtler, Lutz / Seitz, Rainer / Schramm, Wolfgang

    Infection

    2021  Volume 49, Issue 5, Page(s) 1071–1074

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Humans ; SARS-CoV-2 ; Thrombosis ; Vaccination ; Vaccines ; Venous Thrombosis/epidemiology ; Venous Thrombosis/etiology ; Venous Thrombosis/prevention & control
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2021-07-21
    Publishing country Germany
    Document type Letter
    ZDB-ID 185104-4
    ISSN 1439-0973 ; 0300-8126 ; 0173-2129
    ISSN (online) 1439-0973
    ISSN 0300-8126 ; 0173-2129
    DOI 10.1007/s15010-021-01658-x
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    Zs.MO 528: Show issues

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  7. Article ; Online: Thromboinflammation in COVID-19: Can α

    Seitz, Rainer / Gürtler, Lutz / Schramm, Wolfgang

    Journal of thrombosis and haemostasis : JTH

    2020  Volume 19, Issue 2, Page(s) 351–354

    Abstract: The complex COVID-19-associated coagulopathy appears to impair prognosis. Recently, we presented the hypothesis that children are to some extent protected by higher ... ...

    Abstract The complex COVID-19-associated coagulopathy appears to impair prognosis. Recently, we presented the hypothesis that children are to some extent protected by higher α
    MeSH term(s) Animals ; Blood Coagulation ; COVID-19/complications ; COVID-19/metabolism ; COVID-19/virology ; Endothelial Cells/metabolism ; Extracellular Traps/metabolism ; Host-Pathogen Interactions ; Humans ; Inflammation/metabolism ; Inflammation/virology ; Inflammation Mediators/metabolism ; SARS-CoV-2/pathogenicity ; Thrombosis/metabolism ; Thrombosis/virology ; alpha-Macroglobulins/metabolism
    Chemical Substances A2M protein, human ; Inflammation Mediators ; alpha-Macroglobulins
    Language English
    Publishing date 2020-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.15190
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  8. Article ; Online: COVID-19-associated coagulopathy-Hypothesis: Are children protected due to enhanced thrombin inhibition by higher α

    Schramm, Wolfgang / Seitz, Rainer / Gürtler, Lutz

    Journal of thrombosis and haemostasis : JTH

    2020  Volume 18, Issue 9, Page(s) 2416–2418

    MeSH term(s) Adult ; Anticoagulants ; Antithrombins/blood ; Blood Coagulation ; Blood Coagulation Disorders/complications ; COVID-19/complications ; COVID-19/immunology ; Child ; Endothelial Cells/metabolism ; Family Health ; Hemorrhage ; Humans ; Male ; Models, Theoretical ; Phenotype ; Pregnancy-Associated alpha 2-Macroglobulins/metabolism ; Pulmonary Embolism/complications ; Thrombin/antagonists & inhibitors ; Venous Thrombosis/complications
    Chemical Substances Anticoagulants ; Antithrombins ; Pregnancy-Associated alpha 2-Macroglobulins ; Thrombin (EC 3.4.21.5)
    Keywords covid19
    Language English
    Publishing date 2020-07-13
    Publishing country England
    Document type Letter
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.15013
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  10. Article ; Online: DIC in COVID‐19

    Seitz, Rainer / Schramm, Wolfgang

    Journal of Thrombosis and Haemostasis

    Implications for prognosis and treatment?

    2020  Volume 18, Issue 7, Page(s) 1798–1799

    Keywords Hematology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.14878
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