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  1. Article ; Online: Chronic granulomatous disease as a risk factor for cutaneous lupus in childhood.

    Carvalho, Sandrina / Machado, Susana / Sampaio, Rita / Guedes, Margarida / Vasconcelos, Júlia / Semedo, Diogo / Selores, Manuela

    Dermatology online journal

    2017  Volume 23, Issue 3

    Abstract: Chronic granulomatous disease (CGD) is a primaryimmunodeficiency disorder that affects the phagocyticcells of the innate immune system. It is characterizedby recurrent or persistent infections with granulomaformation. Lupus-like lesions have been ... ...

    Abstract Chronic granulomatous disease (CGD) is a primaryimmunodeficiency disorder that affects the phagocyticcells of the innate immune system. It is characterizedby recurrent or persistent infections with granulomaformation. Lupus-like lesions have been reported incarriers of CGD and less frequently, in patients withCGD. Immunological study in these patients areusually negative. We describe the case of an 8-yearoldboy with CGD who developed chronic and acutecutaneous lupus erythematous with angular cheilitis,oral ulcers, Raynaud phenomenon, and positiveserologies for antinuclear, anticentromere, and anti-Saccharomyces cerevisiae antibodies.
    MeSH term(s) Antibodies, Antinuclear/immunology ; Antibodies, Fungal/immunology ; Cheilitis/complications ; Cheilitis/diagnosis ; Cheilitis/immunology ; Child ; Facial Dermatoses/complications ; Facial Dermatoses/diagnosis ; Facial Dermatoses/immunology ; Facial Dermatoses/pathology ; Foot Dermatoses/complications ; Foot Dermatoses/diagnosis ; Foot Dermatoses/immunology ; Foot Dermatoses/pathology ; Granulomatous Disease, Chronic/complications ; Granulomatous Disease, Chronic/immunology ; Humans ; Lupus Erythematosus, Cutaneous/complications ; Lupus Erythematosus, Cutaneous/diagnosis ; Lupus Erythematosus, Cutaneous/immunology ; Lupus Erythematosus, Cutaneous/pathology ; Male ; Oral Ulcer/complications ; Oral Ulcer/diagnosis ; Oral Ulcer/immunology ; Raynaud Disease/complications ; Raynaud Disease/diagnosis ; Raynaud Disease/immunology ; Risk Factors ; Saccharomyces cerevisiae/immunology
    Chemical Substances Antibodies, Antinuclear ; Antibodies, Fungal ; anticentromere antibody
    Language English
    Publishing date 2017-03-15
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2026239-5
    ISSN 1087-2108 ; 1087-2108
    ISSN (online) 1087-2108
    ISSN 1087-2108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Adult Acne: Prevalence and Portrayal in Primary Healthcare Patients, in the Greater Porto Area, Portugal.

    Semedo, Diogo / Ladeiro, Filipa / Ruivo, Mariana / D'Oliveira, Carlos / De Sousa, Filipa / Gayo, Mariana / Lima, Clara / Magalhães, Frederico / Brandão, Rui / Branco, Maria / Da Silva, Isabel / Batista, Joana / Amado, João / Massa, António / Neves-Amado, João

    Acta medica portuguesa

    2016  Volume 29, Issue 9, Page(s) 507–513

    Abstract: Introduction: Though typically found in adolescents, acne frequently affects the adult population. In Portugal, no representative studies about acne prevalence in greater populational areas are known. This study had the following objectives: calculate ... ...

    Abstract Introduction: Though typically found in adolescents, acne frequently affects the adult population. In Portugal, no representative studies about acne prevalence in greater populational areas are known. This study had the following objectives: calculate acne prevalence in primary healthcare patients; its characteristics, including risk factors for onset and worsening; collect information concerning selfmedication and/or prescribed treatment.
    Material and methods: Application of a questionnaire and physical examination into a convenience sample, composed by adults from20 - 60 years old that visited, in random days, five primary healthcare centers of the Greater Porto area.
    Results: From the 1,055 evaluated adults, acne prevalence was estimated at 61.5%. Only 36.8% of acne suffering adults was awareof their condition. More than half of tobacco users (62.3%) had acne. Just 25% of acne sufferers sought treatment. The most affected areas were the malars, differing from the younger disease form.
    Discussion: Acne prevalence was relatively higher than other studies. The results of this study have confirmed that acne seems to be related with increased calorie intake, tobacco smoking, whole milk and fat-reduced milk consumption, hirsutism, alopecia and seborrhea.
    Conclusion: In the primary healthcare set, more than half of adults were acne sufferers. These numbers show how important primary healthcare services can be in preventing and intervening when managing acne-related risk factors and psychosocial consequences.
    Language English
    Publishing date 2016-09
    Publishing country Portugal
    Document type Journal Article
    ZDB-ID 603078-6
    ISSN 1646-0758 ; 0870-399X
    ISSN (online) 1646-0758
    ISSN 0870-399X
    DOI 10.20344/amp.6626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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