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  1. Article ; Online: Adult Stem Cells: Beyond Regenerative Tool, More as a Bio-Marker in Obesity and Diabetes.

    Sen, Sabyasachi

    Diabetes & metabolism journal

    2020  Volume 43, Issue 6, Page(s) 744–751

    Abstract: Obesity, diabetes, and cardiovascular diseases are increasing rapidly worldwide and it is therefore important to know the effect of exercise and medications for diabetes and obesity on adult stem cells. Adult stem cells play a major role in remodeling ... ...

    Abstract Obesity, diabetes, and cardiovascular diseases are increasing rapidly worldwide and it is therefore important to know the effect of exercise and medications for diabetes and obesity on adult stem cells. Adult stem cells play a major role in remodeling and tissue regeneration. In this review we will focus mainly on two adult stem/progenitor cells such as endothelial progenitor cells and mesenchymal stromal cells in relation to aerobic exercise and diabetes medications, both of which can alter the course of regeneration and tissue remodelling. These two adult precursor and stem cells are easily obtained from peripheral blood or adipose tissue depots, as the case may be and are precursors to endothelium and mesenchymal tissue (fat, bone, muscle, and cartilage). They both are key players in maintenance of cardiovascular and metabolic homeostasis and can act also as useful biomarkers.
    MeSH term(s) Adipose Tissue/pathology ; Adult Stem Cells/drug effects ; Adult Stem Cells/metabolism ; Age Factors ; Biomarkers/metabolism ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Endothelial Progenitor Cells/drug effects ; Endothelial Progenitor Cells/metabolism ; Exercise ; Humans ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Obesity/metabolism ; Obesity/pathology ; Regeneration
    Chemical Substances Biomarkers ; Hypoglycemic Agents
    Language English
    Publishing date 2020-01-04
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2602402-0
    ISSN 2233-6087 ; 2233-6079
    ISSN (online) 2233-6087
    ISSN 2233-6079
    DOI 10.4093/dmj.2019.0175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of the

    Lovi, Jacob M / Sen, Sabyasachi

    The Journal of chemical physics

    2023  Volume 158, Issue 14, Page(s) 141103

    Abstract: The effects of atomic mass in terms of its zero-point vibrational energy, on molar volume, glass transition temperature ... ...

    Abstract The effects of atomic mass in terms of its zero-point vibrational energy, on molar volume, glass transition temperature T
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0147333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Circulating Endothelial Progenitor and Mesenchymal Stromal Cells as Biomarkers for Monitoring Disease Status and Responses to Exercise.

    Gollie, Jared M / Sen, Sabyasachi

    Reviews in cardiovascular medicine

    2023  Volume 23, Issue 12, Page(s) 396

    Abstract: Noncommunicable chronic diseases, such as obesity, cardiovascular disease (CVD), and type 2 diabetes (T2D), pose significant health challenges globally. Important advances have been made in the understanding of the pathophysiologal mechanisms and ... ...

    Abstract Noncommunicable chronic diseases, such as obesity, cardiovascular disease (CVD), and type 2 diabetes (T2D), pose significant health challenges globally. Important advances have been made in the understanding of the pathophysiologal mechanisms and treatment of noncommunicable diseases in recent years. Lack of physical activity is a primary contributor to many noncommunicable diseases including metabolic syndrome, T2D, CVD, and obesity. Certain diabetes medications and non-pharmaceutical interventions, such as physical activity and exercise, are shown to be effective in decreasing the CVD risks associated with heart disease, stroke, obesity, prediabetes, and T2D. The ability to measure and analyze circulating adult stem cells (ASCs) has gained particular interest due to their potential to identify at-risk individuals and implications in various therapeutics. Therefore, the purpose of this narrative review is to (1) provide an overview of ASCs; specifically endothelial progenitor cells (EPCs) and mesenchymal stromal cells (MSCs), (2) describe the responses of these cells to acute and chronic exercise, and (3) highlight the potential effect of exercise on EPCs and MSCs in aging and disease. EPCs are circulating cells, abundantly available in peripheral blood, bone marrow, and umbilical cord, and are defined by cell surface markers such as CD34
    Language English
    Publishing date 2023-09-07
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2108910-3
    ISSN 1530-6550
    ISSN 1530-6550
    DOI 10.31083/j.rcm2312396
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6410: Show issues Location:
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  4. Article ; Online: Coordinated microbial lysis bursts into the drug delivery scene.

    Sen, Sabyasachi / Kunjapur, Aditya M

    Trends in biotechnology

    2023  Volume 41, Issue 3, Page(s) 295–297

    Abstract: To address limitations in dosing and releasing cargo from engineered microbes, Din et al. harnessed a previously designed oscillatory genetic circuit to achieve the synchronized release of cancer-killing protein payloads. Here, we briefly recap this ... ...

    Abstract To address limitations in dosing and releasing cargo from engineered microbes, Din et al. harnessed a previously designed oscillatory genetic circuit to achieve the synchronized release of cancer-killing protein payloads. Here, we briefly recap this study published in 2016 and its transformative impact on the field.
    Language English
    Publishing date 2023-01-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 47474-5
    ISSN 1879-3096 ; 0167-7799
    ISSN (online) 1879-3096
    ISSN 0167-7799
    DOI 10.1016/j.tibtech.2023.01.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2750: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Article ; Online: Kinetics of physical aging of a silicate glass following temperature up- and down-jumps.

    Lancelotti, Ricardo F / Zanotto, Edgar D / Sen, Sabyasachi

    The Journal of chemical physics

    2024  Volume 160, Issue 3

    Abstract: In this article, we investigate the structural relaxation of lithium silicate glass during isothermal physical aging by monitoring the temporal evolution of its refractive index and enthalpy following relatively large (10-40 °C) up- and down-jumps in ... ...

    Abstract In this article, we investigate the structural relaxation of lithium silicate glass during isothermal physical aging by monitoring the temporal evolution of its refractive index and enthalpy following relatively large (10-40 °C) up- and down-jumps in temperature. The Kohlrausch-Williams-Watts function aptly describes the up- and down-jump data when analyzed separately. For temperature down-jumps, the glass exhibits a typical stretched exponential kinetic behavior with the non-exponentiality parameter β < 1, whereas up-jumps show a compressed exponential behavior (β > 1). We analyzed these datasets using the non-exponential and non-linear Tool-Narayanaswamy-Moynihan (TNM) model, aiming to provide a comprehensive description of the primary or α-relaxation of the glass. This model described both up- and down-jump datasets using a single value of β ≤ 1. However, the standard TNM model exhibited a progressively reduced capacity to describe the data for larger temperature jumps, which is likely a manifestation of the temperature dependence of the non-exponentiality or non-linearity of the relaxation process. We hypothesize that the compressed exponential relaxation kinetics observed for temperature up-jumps stems from a nucleation-growth-percolation-based evolution on the dynamically mobile regions within the structure, leading to a self-acceleration of the dynamics. On the other hand, temperature down-jumps result in self-retardation, as the slow-relaxing denser regions percolate in the structure to give rise to a stretched exponential behavior.
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0185538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 49/16: Show issues

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  6. Article ; Online: Dynamics in inorganic glass-forming liquids by NMR spectroscopy.

    Sen, Sabyasachi

    Progress in nuclear magnetic resonance spectroscopy

    2019  Volume 116, Page(s) 155–176

    Abstract: Dynamical NMR spectroscopy provides unique mechanistic understanding of the transport and relaxation processes in glass-forming liquids over timescales typically ranging from ~ ... ...

    Abstract Dynamical NMR spectroscopy provides unique mechanistic understanding of the transport and relaxation processes in glass-forming liquids over timescales typically ranging from ~10
    Language English
    Publishing date 2019-11-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 209325-x
    ISSN 1873-3301 ; 0079-6565
    ISSN (online) 1873-3301
    ISSN 0079-6565
    DOI 10.1016/j.pnmrs.2019.11.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2654: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: Characterization of the Pb Coordination Environment and Its Connectivity in Lead Silicate Glasses: Results from 2D

    Sen, Sabyasachi / Lancelotti, Ricardo F / Hung, Ivan / Gan, Zhehong

    The journal of physical chemistry. B

    2024  Volume 128, Issue 11, Page(s) 2811–2820

    Abstract: The Pb-O coordination environment in binary (PbO) ...

    Abstract The Pb-O coordination environment in binary (PbO)
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.3c08307
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Novel Therapeutics in Nonalcoholic Fatty Liver Disease: A Focus on Adult Stem Cells.

    Nandula, Seshagiri Rao / Nylen, Eric S / Sen, Sabyasachi

    Metabolic syndrome and related disorders

    2023  Volume 21, Issue 2, Page(s) 71–78

    Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder that is associated with abnormal accumulation of fat in the liver, which can lead to a wide variety of pathological liver defects and associated insulin resistance (IR), ... ...

    Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder that is associated with abnormal accumulation of fat in the liver, which can lead to a wide variety of pathological liver defects and associated insulin resistance (IR), obesity, hypertension, dyslipidemia, diabetes, and cardiovascular disease. The molecular mechanisms that cause the initiation and progression of NAFLD are not fully understood. Increased lipolysis and
    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/etiology ; Diabetes Mellitus, Type 2/complications ; Liver/metabolism ; Inflammation/complications ; Insulin Resistance ; Adult Stem Cells/metabolism
    Language English
    Publishing date 2023-01-10
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2151220-6
    ISSN 1557-8518 ; 1540-4196
    ISSN (online) 1557-8518
    ISSN 1540-4196
    DOI 10.1089/met.2022.0069
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5950: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article ; Online: New approaches to dissect leaf hydraulics reveal large gradients in living tissues of tomato leaves.

    Jain, Piyush / Huber, Annika E / Rockwell, Fulton E / Sen, Sabyasachi / Holbrook, N Michele / Stroock, Abraham D

    The New phytologist

    2024  Volume 242, Issue 2, Page(s) 453–465

    Abstract: The water status of the living tissue in leaves is critical in determining plant function and global exchange of water and ... ...

    Abstract The water status of the living tissue in leaves is critical in determining plant function and global exchange of water and CO
    MeSH term(s) Solanum lycopersicum ; Plant Leaves/physiology ; Water/physiology ; Xylem/physiology ; Plant Transpiration
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 208885-x
    ISSN 1469-8137 ; 0028-646X
    ISSN (online) 1469-8137
    ISSN 0028-646X
    DOI 10.1111/nph.19585
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    In stock of ZB MED Bonn / Germany

    Z 868: Show issues

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  10. Article: Aging-Induced Structural Evolution of a GeSe₂ Glass Network: The Role of Homopolar Bonds

    Yuan, Bing / Chen, Hao / Sen, Sabyasachi

    Journal of physical chemistry. 2022 Jan. 21, v. 126, no. 4

    2022  

    Abstract: The structural evolution of GeSe₂ glass during aging is studied using Raman spectroscopy and density relaxation measurements. The Raman spectra indicate volume- and entropy-driven changes in the relative concentrations of the corner-sharing (CS) and edge- ...

    Abstract The structural evolution of GeSe₂ glass during aging is studied using Raman spectroscopy and density relaxation measurements. The Raman spectra indicate volume- and entropy-driven changes in the relative concentrations of the corner-sharing (CS) and edge-sharing (ES) GeSe₄ tetrahedra and in the degree of chemical order of the tetrahedral network during aging at 65 °C below the nominal glass transition temperature. The attendant structural changes involve a progressive increase in the CS:ES ratio and in the chemical order that can be expressed in the form of a reaction Ge–Ge + Se–Se → 2 Ge–Se, which shifts to the right, with lowering of fictive temperature. The isothermal relaxation of both the structure and density during aging displays rather similar stretched exponential kinetics with a stretching exponent β ∼0.54 and an average relaxation time of ∼13.5 h. In situ high-temperature Raman spectroscopic measurements indicate that structural relaxation does not affect the anharmonicity of the vibrational potential wells in the energy landscape of GeSe₂ glass.
    Keywords Raman spectroscopy ; geometry ; glass ; glass transition temperature ; physical chemistry
    Language English
    Dates of publication 2022-0121
    Size p. 946-952.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1520-5207
    DOI 10.1021/acs.jpcb.1c08836
    Database NAL-Catalogue (AGRICOLA)

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