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  1. Article ; Online: Letter to the Editor: Can semaglutide result in a tangible cardiovascular benefit in recipients of liver transplants?

    Sensi, Bruno / Manzia, Tommaso M

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2024  

    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1097/LVT.0000000000000364
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    Zs.A 4702: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Comment on: The impact of routine division of the greater omentum on small bowel obstruction after Roux-en-Y gastric bypass.

    Sensi, Bruno / Gentileschi, Paolo

    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

    2022  Volume 19, Issue 3, Page(s) 184–185

    MeSH term(s) Humans ; Gastric Bypass ; Omentum/surgery ; Intestine, Small/surgery ; Intestinal Obstruction/surgery ; Mesentery/surgery ; Obesity, Morbid/surgery ; Laparoscopy ; Anastomosis, Roux-en-Y
    Language English
    Publishing date 2022-12-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 2274243-8
    ISSN 1878-7533 ; 1550-7289
    ISSN (online) 1878-7533
    ISSN 1550-7289
    DOI 10.1016/j.soard.2022.12.005
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    Zs.A 6572: Show issues Location:
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  3. Article ; Online: Ambulatory management of perianal Crohn's disease during the COVID-19 pandemic.

    Divizia, A / Sensi, B / Sica, G S

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2020  Volume 22, Issue 6, Page(s) 645–646

    MeSH term(s) Abscess/etiology ; Abscess/surgery ; Ambulatory Care/methods ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Crohn Disease/complications ; Crohn Disease/therapy ; Drainage/methods ; Humans ; Pandemics ; Personal Protective Equipment ; Pneumonia, Viral/epidemiology ; Proctoscopy/methods ; Rectal Fistula/etiology ; Rectal Fistula/surgery ; SARS-CoV-2 ; Tumor Necrosis Factor Inhibitors/therapeutic use
    Chemical Substances Tumor Necrosis Factor Inhibitors
    Keywords covid19
    Language English
    Publishing date 2020-05-18
    Publishing country England
    Document type Letter
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15104
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    Zs.A 5799: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article ; Online: Surgical management of colon cancer in ulcerative colitis patients with orthotopic liver transplant for primary sclerosing cholangitis. A systematic review.

    Sica, G S / Sensi, B / Siragusa, L / Blasi, F / Crispino, B / Pirozzi, B / Angelico, R / Biancone, L / Khan, J

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2023  Volume 49, Issue 10, Page(s) 106922

    Abstract: Introduction: Colon cancer in ulcerative colitis patients with liver transplant (UCCOLT) due to primary sclerosing cholangitis carries significant treatment challenges. Aim of this literature search is to review management strategies and provide a ... ...

    Abstract Introduction: Colon cancer in ulcerative colitis patients with liver transplant (UCCOLT) due to primary sclerosing cholangitis carries significant treatment challenges. Aim of this literature search is to review management strategies and provide a framework to facilitate the decisional process in this clinical setting.
    Methods: PRISMA-compliant systematic search was followed by critical expert commentary of the results and development of a surgical management algorithm. Endpoints included surgical management, operative strategies, functional and survival outcomes. Technical and strategics aspects with particular regard to the choice of reconstruction were evaluated to tentatively develop an integrated algorithm.
    Results: Ten studies reporting treatment of 20 UCCOLT patients were identified after screening. Nine patients underwent proctocolectomy and end-ileostomy (PC) and eleven had restorative ileal pouch-anal anastomosis (IPAA). Reported results for perioperative outcomes, oncological outcomes, and graft loss were comparable for both procedures. There were no reports of subtotal colectomies and ileo-rectal anastomosis (IRA).
    Conclusions: Literature in the field is scarce and decision-making is particularly complex. PC and IPAA have been reported with good results. Nevertheless, IRA may also be considered in UCCOLT patients in selected cases, reducing the risks of sepsis, OLT and pouch failure; furthermore, in young patients, it has the advantage of preserving fertility or sexual function. The proposed treatment algorithm may represent a valuable support in guiding surgical strategy.
    MeSH term(s) Humans ; Colitis, Ulcerative/complications ; Colitis, Ulcerative/surgery ; Liver Transplantation/adverse effects ; Cholangitis, Sclerosing/complications ; Cholangitis, Sclerosing/surgery ; Proctocolectomy, Restorative/methods ; Anastomosis, Surgical/methods ; Colonic Neoplasms/complications ; Colonic Neoplasms/surgery ; Treatment Outcome ; Postoperative Complications/etiology
    Language English
    Publishing date 2023-05-13
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2023.04.021
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    Zs.A 1149: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 549: Show issues

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  5. Article ; Online: Mesenteric closure with polymer-ligating clips after right colectomy with complete mesocolic excision for cancer and mesentery-based ileocolic resection for Crohn's disease.

    Sica, G S / Franceschilli, M / Sensi, B / Siragusa, L / Vinci, D / Bellato, V

    Techniques in coloproctology

    2021  Volume 25, Issue 9, Page(s) 1079–1084

    Abstract: Mesenteric closure following right colectomy remains controversial and, following the advent of laparoscopic surgery, many surgeons do not routinely close the mesentery after colorectal resection. Nevertheless, especially after the introduction of ... ...

    Abstract Mesenteric closure following right colectomy remains controversial and, following the advent of laparoscopic surgery, many surgeons do not routinely close the mesentery after colorectal resection. Nevertheless, especially after the introduction of operations such as right colectomy with complete mesocolic excision and ileocolic resections with extensive mesentery removal for Crohn's disease, the wide mesenteric defect resulting from the dissections can certainly expose the patients to complications such as internal hernias or volvuli. In general, mesenteric closure requires intracorporeal suturing. We describe a simple technique for the closure of the mesentery after surgical resection using polymer-ligating clips. This novel technique seems to minimize the time, effort and risk inherent to the procedure, even after large mesenteric excisions.
    MeSH term(s) Colectomy ; Colonic Neoplasms/surgery ; Crohn Disease/surgery ; Humans ; Laparoscopy ; Mesentery/surgery ; Mesocolon/surgery ; Polymers ; Surgical Instruments
    Chemical Substances Polymers
    Language English
    Publishing date 2021-07-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-021-02493-w
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    Zs.A 5842: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Ambulatory management of perianal Crohn’s disease during the COVID‐19 pandemic

    Divizia, A. / Sensi, B. / Sica, G. S.

    Colorectal Disease

    2020  Volume 22, Issue 6, Page(s) 645–646

    Keywords Gastroenterology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15104
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Zs.A 5799: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: All the Routes for Laparoscopic Liver Segment VIII Resection: A Comprehensive Review of Surgical Techniques.

    Anselmo, Alessandro / Sensi, Bruno / Bacchiocchi, Giulia / Siragusa, Leandro / Tisone, Giuseppe

    Frontiers in oncology

    2022  Volume 12, Page(s) 864867

    Abstract: Liver surgery is highly demanding for anatomical, physiological and technical reasons, and minimally invasive approaches have been implemented at a slower rate. Today, laparoscopic liver resection is a standard of care in many occasions, yet specific ... ...

    Abstract Liver surgery is highly demanding for anatomical, physiological and technical reasons, and minimally invasive approaches have been implemented at a slower rate. Today, laparoscopic liver resection is a standard of care in many occasions, yet specific operations remain particularly challenging and generally performed in open surgery. In particular, SVIII resection may be considered one of the most difficult due to anatomical characteristics including its sub-diaphragmatic position, the deep-lying Glissonean pedicle and the close contact with the inferior vena cava and right and middle hepatic veins. Many techniques have risen to overcome technical difficulties, and today laparoscopic SVIII resection has been demonstrated to be feasible. This review provides a complete picture of current approaches, focusing on all techniques reported so far with critical appraisal of each, discussing and explaining benefits and pitfalls.
    Language English
    Publishing date 2022-04-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.864867
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  9. Article: Primary versus Salvage Liver Transplantation after Curative-Intent Resection or Radiofrequency Ablation for Hepatocellular Carcinoma: Long-Term Oncological Outcomes.

    Anselmo, Alessandro / Siragusa, Leandro / Brigato, Paolo / Riccetti, Camilla / Collini, Andrea / Sensi, Bruno / Tisone, Giuseppe

    Cancers

    2023  Volume 15, Issue 20

    Abstract: Liver transplantation for hepatocellular carcinoma (HCC) may be performed ab initio, primary liver transplantation (PLT), or for HCC recurrence after previous treatments such as liver resection (LR) or radiofrequency ablation (RFA), salvage liver ... ...

    Abstract Liver transplantation for hepatocellular carcinoma (HCC) may be performed ab initio, primary liver transplantation (PLT), or for HCC recurrence after previous treatments such as liver resection (LR) or radiofrequency ablation (RFA), salvage liver transplantation (SLT). The aim of this study was to evaluate the oncological outcomes of SLT vs. PLT. For this, a retrospective study was carried out on patients undergoing liver transplantation for HCC. The outcomes of PLT were compared with those of SLT. The primary outcome was disease-free survival (DFS). The secondary outcomes included overall survival (OS), cancer-specific survival (CSS), and major postoperative complications. A sub-analysis of SLT-LR and SLT-RFA was also performed. In total, 141 patients were included: 96 underwent PLT and 45 SLT. Among the SLT group, 25 patients had undergone previous LR while 20 had had RFA. There were no differences in the major postoperative complications. Unadjusted DFS was significantly longer in the PLT group (
    Language English
    Publishing date 2023-10-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15205030
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  10. Article ; Online: Volume-outcome relationship in rectal cancer surgery.

    Siragusa, L / Sensi, B / Vinci, D / Franceschilli, M / Pathirannehalage Don, C / Bagaglini, G / Bellato, V / Campanelli, M / Sica, G S

    Discover. Oncology

    2021  Volume 12, Issue 1, Page(s) 11

    Abstract: Introduction: Hospital centralization effect is reported to lower complications and mortality for high risk and complex surgery operations, including colorectal surgery. However, no linear relation between volume and outcome has been demonstrated. Aim ... ...

    Abstract Introduction: Hospital centralization effect is reported to lower complications and mortality for high risk and complex surgery operations, including colorectal surgery. However, no linear relation between volume and outcome has been demonstrated. Aim of the study was to evaluate the increased surgical volume effect on early outcomes of patient undergoing laparoscopic restorative anterior rectal resection (ARR).
    Methods: A retrospective analysis of all consecutive patients undergoing ARR with primary anastomosis between November 2016 and December 2020 after centralization of rectal cancer cases in an academic Centre. Short-term outcomes are compared to those of patients operated in the same unit during the previous 10 years before service centralization. The primary outcome was estimated anastomotic leak rate. Mean operative time, need of conversion, postoperative use of blood transfusion, radicality, in-hospital stay, number and type of complications, readmission and reoperation rate, mortality and 1-year and stoma persistence rates were evaluated as secondary outcomes.
    Results: 86 patients were operated in the study period and outcomes compared to those of 101 patients operated during the previous ten years. Difference in volume of surgery was significant between the two periods (p 0.019) and the estimated leak rate was significantly lower in the higher volume unit (p 0.047). Mean operative time, need of conversion, postoperative use of blood transfusion and in-hospital stay (p < 0.05) were also significantly reduced in Group A.
    Conclusion: This study suggests that the shift toward higher volume in rectal cancer surgery is associated to decreased anastomotic leak rate. Potentiation of lower volume surgical units may yield optimal perioperative outcomes.
    Language English
    Publishing date 2021-04-12
    Publishing country United States
    Document type Journal Article
    ISSN 2730-6011
    ISSN (online) 2730-6011
    DOI 10.1007/s12672-021-00406-9
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