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  1. Article ; Online: Effect of Royal Jelly on Sperm Parameters and Testosterone Levels in Infertile Men

    Sepideh Peivandi / Sepideh Khalili Savadkouhi / Zahra Abbasi / Marzieh Zamaniyan / Noushin Gordani / Siavash Moradi

    Journal of Mazandaran University of Medical Sciences, Vol 31, Iss 206, Pp 43-

    2022  Volume 52

    Abstract: Background and purpose: Complementary medicine plays a major role in treatment of infertility. The aim of this study was to evaluate the effect of royal jelly on sperm parameters and testosterone levels in infertile men. Materials and methods: In this ... ...

    Abstract Background and purpose: Complementary medicine plays a major role in treatment of infertility. The aim of this study was to evaluate the effect of royal jelly on sperm parameters and testosterone levels in infertile men. Materials and methods: In this quasi-experimental study, 100 infertile men attending the infertility treatment center in Sari Imam Khomeini Hospital were monitored for two months and then underwent a spermogram test. Afterwards, they were treated with royal jelly (100 mg/daily) for two months and spermograms were performed again. Statistical analysis was performed in SPSS V21. Results: Royal jelly significantly increased sperm motility, improved morphology, and increased testosterone levels (P≤0.001), but, no significant difference was seen in sperm count before and after consumption of royal jelly (47.76 ± 23.59 and 50.28 ± 29.44, respectively, P≥ 0.2). Conclusion: According to current study, royal jelly could be used as a supplement along with other medications to boost fertility and treat male infertility. (Clinical Trials Registry Number: IRCT20180609040028N2)
    Keywords royal jelly ; sperm ; testosterone ; infertility ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 941
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Mazandaran University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: The Influence of Light on Apoptosis in Preimplantation Mouse Embryos In Vitro

    Sepideh Khalili-Savadkouhi / Abbasali Karimpour Malekshah / Mehri Mirhoseini / Mahmood Moosazadeh / Maryam shahidi

    Research in Molecular Medicine, Vol 2017, Pp 1-

    2018  Volume 11

    Abstract: Background: In vitro culture of mammalian embryos can slow or stop growth completely. This may be due to the medium used, pH, temperature, or light. There is considerable concern about the harmful effect of light in the laboratory environment. Cell ... ...

    Abstract Background: In vitro culture of mammalian embryos can slow or stop growth completely. This may be due to the medium used, pH, temperature, or light. There is considerable concern about the harmful effect of light in the laboratory environment. Cell number and apoptosis are useful parameters that indicate embryonic development and health. In this study, we assessed these two factors in the blastocyst. Materials and methods: A total of 128 embryos were extracted from NMRI mice at the 2-cell stage and were divided into 4 groups. The embryos were exposed to light for 0, 5, 15, and 30 min, and then cultured for 96 h. The degree of embryonic development were recorded every 24 h. Furthermore, several morphologically normal blastocysts were evaluated using the TUNEL assay. Results: There was no significant difference in developmental stages between the experimental and control groups. An evaluation of the percentage of blastomeres and apoptotic cells revealed significant differences among the four groups. The maximum number of apoptotic blastomeres was observed in the group exposed to light for 30 minutes. Conclusion: Up to thirty minutes of white fluorescent light can induce apoptosis in blastomeres, but it does not prevent embryo development.
    Keywords apoptosis ; blastocyst ; mice ; light ; embryonic structures ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2018-12-01T00:00:00Z
    Publisher Mazandaran University of Medical Sciences and Health Services
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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