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  1. Article ; Online: Early rehabilitation using gait exoskeletons is possible in the neurosurgical setting, even in patients with cognitive impairment.

    Apra, C / Serra, M / Robert, H / Carpentier, A

    Neuro-Chirurgie

    2022  Volume 68, Issue 4, Page(s) 458–460

    MeSH term(s) Cognitive Dysfunction ; Exoskeleton Device ; Gait ; Humans ; Robotics
    Language English
    Publishing date 2022-03-05
    Publishing country France
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 207146-0
    ISSN 1773-0619 ; 0028-3770 ; 0150-9586
    ISSN (online) 1773-0619
    ISSN 0028-3770 ; 0150-9586
    DOI 10.1016/j.neuchi.2021.12.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Divergent Acute and Enduring Changes in 50-kHz Ultrasonic Vocalizations in Rats Repeatedly Treated With Amphetamine and Dopaminergic Antagonists: New Insights on the Role of Dopamine in Calling Behavior.

    Serra, Marcello / Costa, Giulia / Onaivi, Emmanuel / Simola, Nicola

    The international journal of neuropsychopharmacology

    2024  Volume 27, Issue 2

    Abstract: Background: Rats emit 50-kHz ultrasonic vocalizations (USVs) in response to nonpharmacological and pharmacological stimuli, with addictive psychostimulants being the most effective drugs that elicit calling behavior in rats. Earlier investigations found ...

    Abstract Background: Rats emit 50-kHz ultrasonic vocalizations (USVs) in response to nonpharmacological and pharmacological stimuli, with addictive psychostimulants being the most effective drugs that elicit calling behavior in rats. Earlier investigations found that dopamine D1-like and D2-like receptors modulate the emission of 50-kHz USVs stimulated in rats by the acute administration of addictive psychostimulants. Conversely, information is lacking on how dopamine D1-like and D2-like receptors modulate calling behavior in rats that are repeatedly treated with addictive psychostimulants.
    Methods: We evaluated the emission of 50-kHz USVs in rats repeatedly treated (×5 on alternate days) with amphetamine (1 mg/kg, i.p.) either alone or together with (1) SCH 23390 (0.1-1 mg/kg, s.c.), a dopamine D1 receptor antagonist; (2) raclopride (0.3-1 mg/kg, s.c.), a selective dopamine D2 receptor antagonist; or (3) a combination of SCH 23390 and raclopride (0.1 + 0.3 mg/kg, s.c.). Calling behavior of rats was recorded following pharmacological treatment, as well as in response to the presentation of amphetamine-paired cues and to amphetamine challenge (both performed 7 days after treatment discontinuation).
    Results: Amphetamine-treated rats displayed a sensitized 50-kHz USV emission during repeated treatment, as well as marked calling behavior in response to amphetamine-paired cues and to amphetamine challenge. Antagonism of D1 or D2 receptors either significantly suppressed or attenuated the emission of 50-kHz USVs in amphetamine-treated rats, with a maximal effect after synergistic antagonism of both receptors.
    Conclusions: These results shed further light on how dopamine transmission modulates the emission of 50-kHz USVs in rats treated with psychoactive drugs.
    MeSH term(s) Rats ; Animals ; Amphetamine/pharmacology ; Dopamine ; Dopamine Antagonists/pharmacology ; Raclopride ; Ultrasonics ; Vocalization, Animal ; Central Nervous System Stimulants/pharmacology
    Chemical Substances Amphetamine (CK833KGX7E) ; Dopamine (VTD58H1Z2X) ; Dopamine Antagonists ; Raclopride (430K3SOZ7G) ; Central Nervous System Stimulants
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440129-0
    ISSN 1469-5111 ; 1461-1457
    ISSN (online) 1469-5111
    ISSN 1461-1457
    DOI 10.1093/ijnp/pyae001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Demographic monitoring of the invasive ladder snake on Formentera (Balearic Islands, Spain)

    Febrer‐Serra, M. / Lassnig, N. / Colomar, V. / Picó, G. / Sureda, A. / Pinya, S.

    Journal of Zoology. 2023 July, v. 320, no. 3, p. 236-247

    2023  , Page(s) 236–247

    Abstract: The ladder snake Zamenis scalaris was first reported in 2006 in Formentera (Balearic Islands, Spain), until then a snake‐free Mediterranean island. Since 2016, intense control campaigns have been carried out and, for the first time, snake captures over ... ...

    Abstract The ladder snake Zamenis scalaris was first reported in 2006 in Formentera (Balearic Islands, Spain), until then a snake‐free Mediterranean island. Since 2016, intense control campaigns have been carried out and, for the first time, snake captures over 2017–2020 have been used to analyze the sex ratio, age, fat percentage, population density, and seasonality of this invasive population. The male‐biased sex ratio found in the present work could be the result of capture biases caused by different detection probabilities between sexes. A reduction of snake body length over time was observed, which could indicate a depletion of the larger snakes due to intense snake capture. The highest capture frequencies of both sexes were reported in May and June, coinciding with the mate searching period in the species native range and indicating that snakes increase their movements during this period. Size‐specific survivorship curves indicated a drop in survivorship at medium sizes, which suggested a survival cost associated with reproduction, presumably due to increased mortality during the mating season. Population density decreased from 1.812 snakes/ha in 2017 to 0.669 snakes/ha in 2020. Evidence obtained in the present work has allowed to evaluate the main ecological aspects of Z. scalaris and the current state of the population of this invasive snake on the island of Formentera. Results showed that the population is well established in Formentera, but prolonged control campaigns have caused its decline. This study becomes a starting point to improve the management and control programs of invasive snake populations in the Balearic Islands. Long‐term control as well as the improvement of the detection and capture of adult females are strongly recommended to attempt the eradication of Z. scalaris in Formentera.
    Keywords adults ; body length ; invasive species ; population density ; reproduction ; sex ratio ; snakes ; survival rate ; zoology ; Spain
    Language English
    Dates of publication 2023-07
    Size p. 236-247
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 1471807-8
    ISSN 1469-7998 ; 0952-8369
    ISSN (online) 1469-7998
    ISSN 0952-8369
    DOI 10.1111/jzo.13065
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Optimal locomotion for limbless crawlers.

    Santhosh, Sreejith / Serra, Mattia

    Physical review. E

    2022  Volume 106, Issue 2-1, Page(s) 24610

    Abstract: Limbless crawling is ubiquitous in biology, from cells to organisms. We develop and analyze a model for the dynamics of one-dimensional elastic crawlers, subject to active stress and deformation-dependent friction with the substrate. We find that the ... ...

    Abstract Limbless crawling is ubiquitous in biology, from cells to organisms. We develop and analyze a model for the dynamics of one-dimensional elastic crawlers, subject to active stress and deformation-dependent friction with the substrate. We find that the optimal active stress distribution that maximizes the crawler's center-of-mass displacement given a fixed amount of energy input is a traveling wave. This theoretical optimum corresponds to peristalsislike extension-contraction waves observed in biological organisms, possibly explaining the prevalence of peristalsis as a convergent gait across species. Our theory elucidates key observations in biological systems connecting the anchoring phase of a crawler to the retrograde and prograde distinction seen in peristaltic waves among various organisms. Using our optimal gait solution, we derive a scaling relation between the crawling speed and body mass, explaining experiments on earthworms with three orders of magnitude body mass variations. Our results offer insights and tools for optimal bioinspired crawling robots design with finite battery capacity.
    Language English
    Publishing date 2022-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.106.024610
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Training of health referents at child care centers. Experience in Argentina.

    Serra, M Elina / Soria, Rose M

    Archivos argentinos de pediatria

    2022  Volume 120, Issue 2, Page(s) 122–128

    Abstract: An adequate child care helps to mitigate the effects of social adversity. Health prevention is a part of it. This is an innovative training program for health referents in child care centers that cater to vulnerable populations in Buenos Aires, Argentina. ...

    Title translation Formación de referentes de salud en centros de cuidado infantil. Experiencia en Argentina.
    Abstract An adequate child care helps to mitigate the effects of social adversity. Health prevention is a part of it. This is an innovative training program for health referents in child care centers that cater to vulnerable populations in Buenos Aires, Argentina. It consisted in training child care center staff, followed by the implementation, over 4 months, of an improvement plan developed by each participant in their center, with ongoing advisory support. In total, 26 participants from 19 centers completed the program. In total, 35 out of 49 goals proposed in the plans were achieved, including the certification in cardiopulmonary resuscitation, staff and family training, development of center policies, and improved resource management. Preventive care offered in child care centers may be improved via a simple and inexpensive intervention, including in unfavorable conditions.
    MeSH term(s) Argentina ; Child ; Child Care ; Child Day Care Centers ; Eating ; Humans
    Language Spanish
    Publishing date 2022-01-25
    Publishing country Argentina
    Document type Journal Article
    ZDB-ID 424449-7
    ISSN 1668-3501 ; 0325-0075 ; 0004-0487
    ISSN (online) 1668-3501
    ISSN 0325-0075 ; 0004-0487
    DOI 10.5546/aap.2022.eng.122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Body size variability across habitats in the Brachionus plicatilis cryptic species complex.

    Walczyńska, Aleksandra / Serra, Manuel

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 6912

    Abstract: The body size response to temperature is one of the most recognizable but still poorly understood ecological phenomena. Other covarying environmental factors are frequently invoked as either affecting the strength of that response or even driving this ... ...

    Abstract The body size response to temperature is one of the most recognizable but still poorly understood ecological phenomena. Other covarying environmental factors are frequently invoked as either affecting the strength of that response or even driving this pattern. We tested the body size response in five species representing the Brachionus plicatilis cryptic species complex, inhabiting 10 brackish ponds with different environmental characteristics. Principal Component Analysis selected salinity and oxygen concentration as the most important factors, while temperature and pH were less influential in explaining variation of limnological parameters. Path analysis showed a positive interclonal effect of pH on body size. At the interspecific level, the size response was species- and factor-dependent. Under the lack of a natural thermo-oxygenic relationship, the negative response of size to temperature, expected according to 'size-to-temperature response' rules, disappeared, but a positive response of size to oxygen, expected according to predictions selecting oxygen as a factor actually driving these rules, remained. Our results confirm the crucial role of oxygen in determining the size-to-temperature patterns observed in the field.
    MeSH term(s) Animals ; Body Size ; Ecosystem ; Oxygen/pharmacology ; Rotifera/physiology ; Temperature
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2022-04-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-10638-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Oral care with chlorhexidine: One size does not fit all.

    Llaurado-Serra, M / Afonso, E / Mellinghoff, J / Conoscenti, E / Deschepper, M

    Enfermeria intensiva

    2023  Volume 34, Issue 4, Page(s) 227–228

    MeSH term(s) Chlorhexidine ; Anti-Infective Agents, Local ; Mouthwashes
    Chemical Substances Chlorhexidine (R4KO0DY52L) ; Anti-Infective Agents, Local ; Mouthwashes
    Language English
    Publishing date 2023-12-01
    Publishing country Spain
    Document type Letter
    ISSN 2529-9840
    ISSN (online) 2529-9840
    DOI 10.1016/j.enfie.2023.08.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Radon risk mapping: A new geostatistical method based on Lorenz Curve and Gini index.

    Loffredo, F / Scala, A / Serra, M / Quarto, M

    Journal of environmental radioactivity

    2021  Volume 233, Page(s) 106612

    Abstract: In confined spaces such as living environments and workplaces, the concentration levels of radon ( ... ...

    Abstract In confined spaces such as living environments and workplaces, the concentration levels of radon (Rn
    MeSH term(s) Air Pollutants, Radioactive/analysis ; Air Pollution, Indoor/analysis ; Humans ; Radiation Monitoring ; Radon/analysis ; Soil Pollutants, Radioactive/analysis ; Spatial Analysis
    Chemical Substances Air Pollutants, Radioactive ; Soil Pollutants, Radioactive ; Radon (Q74S4N8N1G)
    Language English
    Publishing date 2021-04-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1483112-0
    ISSN 1879-1700 ; 0265-931X
    ISSN (online) 1879-1700
    ISSN 0265-931X
    DOI 10.1016/j.jenvrad.2021.106612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effect of inulin on breath hydrogen, postprandial glycemia, gut hormone release, and appetite perception in RYGB patients: a prospective, randomized, cross-over pilot study.

    Steinert, R E / Mueller, M / Serra, M / Lehner-Sigrist, S / Frost, G / Gero, D / Gerber, P A / Bueter, M

    Nutrition & diabetes

    2024  Volume 14, Issue 1, Page(s) 9

    Abstract: Background and objective: Large intestinal fermentation of dietary fiber may control meal-related glycemia and appetite via the production of short-chain fatty acids (SCFA) and the secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY). We ... ...

    Abstract Background and objective: Large intestinal fermentation of dietary fiber may control meal-related glycemia and appetite via the production of short-chain fatty acids (SCFA) and the secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY). We investigated whether this mechanism contributes to the efficacy of the Roux-en-Y gastric bypass (RYGB) by assessing the effect of oligofructose-enriched inulin (inulin) vs. maltodextrin (MDX) on breath hydrogen (a marker of intestinal fermentation), plasma SCFAs, gut hormones, insulin and blood glucose concentrations as well as appetite in RYGB patients.
    Method: Eight RYGB patients were studied on two occasions before and ~8 months after surgery using a cross-over design. Each patient received 300 ml orange juice containing 25 g inulin or an equicaloric load of 15.5 g MDX after an overnight fast followed by a fixed portion snack served 3 h postprandially. Blood samples were collected over 5 h and breath hydrogen measured as well as appetite assessed using visual analog scales.
    Results: Surgery increased postprandial secretion of GLP-1 and PYY (P ≤ 0.05); lowered blood glucose and plasma insulin increments (P ≤ 0.05) and reduced appetite ratings in response to both inulin and MDX. The effect of inulin on breath hydrogen was accelerated after surgery with an increase that was earlier in onset (2.5 h vs. 3 h, P ≤ 0.05), but less pronounced in magnitude. There was, however, no effect of inulin on plasma SCFAs or plasma GLP-1 and PYY after the snack at 3 h, neither before nor after surgery. Interestingly, inulin appeared to further potentiate the early-phase glucose-lowering and second-meal (3-5 h) appetite-suppressive effect of surgery with the latter showing a strong correlation with early-phase breath hydrogen concentrations.
    Conclusion: RYGB surgery accelerates large intestinal fermentation of inulin, however, without measurable effects on plasma SCFAs or plasma GLP-1 and PYY. The glucose-lowering and appetite-suppressive effects of surgery appear to be potentiated with inulin.
    MeSH term(s) Humans ; Inulin/pharmacology ; Appetite ; Pilot Projects ; Gastric Bypass ; Blood Glucose ; Cross-Over Studies ; Prospective Studies ; Peptide YY ; Glucagon-Like Peptide 1 ; Perception ; Insulins
    Chemical Substances Inulin (9005-80-5) ; Blood Glucose ; Peptide YY (106388-42-5) ; Glucagon-Like Peptide 1 (89750-14-1) ; Insulins
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2609314-5
    ISSN 2044-4052 ; 2044-4052
    ISSN (online) 2044-4052
    ISSN 2044-4052
    DOI 10.1038/s41387-024-00267-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Impact of Behavioral Lifestyle Intervention on Inflammatory Cytokines in Older Adults Living With Type 2 Diabetes: A Feasibility Study.

    Jiwani, Rozmin / Serra, Monica / Espinoza, Sara / Berndt, Andrea / Patel, Darpan

    Inquiry : a journal of medical care organization, provision and financing

    2024  Volume 61, Page(s) 469580241248126

    Abstract: Objective: This study investigates the effects of a behavioral lifestyle intervention on inflammatory cytokines and frailty in older adults (≥ 65 years) with type 2 diabetes (T2D).: Method: We conducted a single-arm, 6-month intervention supplemented ...

    Abstract Objective: This study investigates the effects of a behavioral lifestyle intervention on inflammatory cytokines and frailty in older adults (≥ 65 years) with type 2 diabetes (T2D).
    Method: We conducted a single-arm, 6-month intervention supplemented with diet and activity self-monitoring technology. We assessed frailty using Fried criteria and quantified inflammatory cytokines (interleukin [IL]-2, IL-4, IL-6, IL-8, IL-10, granulocyte-macrophage colony-stimulating-factor [GM-CSF], interferon [IFN-γ], tumor necrosis factor [TNF-α]) using a multiplex assay. We used paired t-tests with significance at
    Results: Eighteen participants completed the study (mean ± SD: 71.5 ± 5.3 years; BMI: 34 ± 6 kg/m
    Discussion: The study highlights the importance of behavioral lifestyle intervention in improving inflammatory cytokines and frailty in older adults.
    MeSH term(s) Humans ; Aged ; Cytokines/pharmacology ; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology ; Diabetes Mellitus, Type 2/therapy ; Frailty ; Feasibility Studies ; Tumor Necrosis Factor-alpha/pharmacology ; Life Style
    Chemical Substances Cytokines ; Granulocyte-Macrophage Colony-Stimulating Factor (83869-56-1) ; Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2024-04-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 42153-4
    ISSN 1945-7243 ; 0046-9580
    ISSN (online) 1945-7243
    ISSN 0046-9580
    DOI 10.1177/00469580241248126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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