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Article: Codon and Reverse Codon: A Theoretical Approach to Reinterpret the Genetic Code Table.

Serra, Nicola / Di Carlo, Paola

2023 Volume 15, Issue 11, Page(s) e48598

Abstract: The genetic code table represents a fundamental scheme to translate a genetic code into a sequence of amino acids and, therefore, the possibility of operating the synthesis of all the proteins necessary for the life of organisms. Unfortunately, the ... ...

Abstract	The genetic code table represents a fundamental scheme to translate a genetic code into a sequence of amino acids and, therefore, the possibility of operating the synthesis of all the proteins necessary for the life of organisms. Unfortunately, the various biological mechanisms are not fully clear. Hence, in this report, we analyzed the genetic code table and the amino acids codified by codons with an original theoretical and statistical approach based on the concept of permutations. We found an interesting reinterpretation of many codons, as reverse codons, which could help clarify some as-yet-unknown aspects in the field of protein folding.
Language	English
Publishing date	2023-11-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.48598
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The distribution of different intensity demanding scenarios in elite rink hockey players using an electronic performance tracking system.

Fernández, Daniel / Cadefau, Joan A / Serra, Noemí / Carmona, Gerard

PloS one

2023 Volume 18, Issue 3, Page(s) e0282788

Abstract: Despite the traditional use of average values for determining physical demands, the intermittent and fluctuating nature of team sports may lead to underestimation of the most demanding scenarios. All the most demanding scenario-related investigations to ... ...

Abstract	Despite the traditional use of average values for determining physical demands, the intermittent and fluctuating nature of team sports may lead to underestimation of the most demanding scenarios. All the most demanding scenario-related investigations to date only report one maximal scenario per game, the greatest. However, the latest research on this subject has shown additional scenarios of equal or similar magnitude that most researchers have not considered. This repetition concept started a new way of describing competition and training loads; then the study aims were: first, to quantify and assess differences between playing positions in terms of the most demanding scenarios in official matches; and second, to quantify and assess the differences between playing positions in the repetition of different intensity scenarios relative to the most demanding individual scenario. We monitored nine professional rink hockey players (7 exterior and 2 interior players) in 18 competitive matches using an electronic performance tracking system. The interior players are closest to the opponent's goal, while the exterior players are farthest from it. Peak physical demands variables included total distance (m), distance covered at >18 km·h-1 (m), the number of accelerations (≥2 m∙s-2, count) and decelerations (≤-2 m∙s-2, count) in 30 s. An average from the top three individual most demanding scenarios was used to define a reference value to quantify the distribution scenario repetition during matches. The results showed that peak demands in rink hockey are position-dependent, with more distance covered by exterior players and more accelerations performed by interior players. In addition, rink hockey matches include multiple scenario exposures that are close to the peak physical demands of a match. Using the results of this study, coaches can prepare tailored training plans for each position, focusing on distances covered or accelerations for exterior players.
MeSH term(s)	Hockey ; Athletic Performance ; Running ; Heart Rate ; Electronics ; Geographic Information Systems
Language	English
Publishing date	2023-03-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0282788
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Article ; Online: Respuesta a "Consideraciones sobre las prescripciones antimicrobianas en urgencias".

Argelich Ibáñez, R / Juan-Serra, N

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

2019 Volume 32, Issue 1, Page(s) 95–96

Title translation	Comment on: Considerations in antimicrobial prescribing in the emergency department.
MeSH term(s)	Anti-Infective Agents/therapeutic use ; Drug Prescriptions ; Drug Utilization ; Emergency Medical Services ; Emergency Service, Hospital ; Humans
Chemical Substances	Anti-Infective Agents
Language	Spanish
Publishing date	2019-01-24
Publishing country	Spain
Document type	Letter
ZDB-ID	1018135-0
ISSN	1988-9518 ; 0214-3429
ISSN (online)	1988-9518
ISSN	0214-3429
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Prevalence and prognostic meaning of interstitial lung abnormalities in remote CT scans of patients with interstitial lung disease treated with antifibrotic therapy.

García Mullor, M M / Arenas-Jiménez, J J / Ureña Vacas, A / Gayá García-Manso, I / Pérez Pérez, J L / Serra Serra, N / García Sevila, R

Radiologia

2024 Volume 66 Suppl 1, Page(s) S10–S23

Abstract: Objectives: To describe the prevalence and characteristics of interstitial lung abnormalities (ILA) in CT scans performed prior to the initiation of antifibrotics in a series of patients with interstitial lung disease (ILD), and to identify ... ...

Abstract	Objectives: To describe the prevalence and characteristics of interstitial lung abnormalities (ILA) in CT scans performed prior to the initiation of antifibrotics in a series of patients with interstitial lung disease (ILD), and to identify characteristics apparent on early CT scans that could help to predict outcomes. Methods: We conducted a retrospective observational study. The original cohort consisted of 101 patients diagnosed with ILD and treated with antifibrotics in a tertiary hospital. Patients were included if they had a thoracic CT scan performed at least one year before initiation of therapy. They were classified radiologically in three groups: without ILA, with radiological ILA and extensive abnormalities. ILA were classified as subpleural fibrotic, subpleural non-fibrotic and non-subpleural. The initial scan and the latest CT scan performed before treatment were read for assessing progression. The relationship between CT findings of fibrosis and the radiological progression rate and mortality were analyzed. Results: We included 50 patients. Only 1 (2%) had a normal CT scan, 25 (50%) had extensive alterations and 24 (48%) had radiological criteria for ILA, a median of 98.2 months before initiation of antifibrotics, of them 18 (75%) had a subpleural fibrotic pattern. Significant bronchiectasis and obvious honeycombing in the lower zones were associated with shorter survival (p = 0.04). Obvious honeycombing in the lower zones was also significantly (p < 0.05) associated with a faster progression rate. Conclusions: Fibrotic ILAs are frequent in remote scans of patients with clinically relevant ILD, long before they require antifibrotics. Findings of traction bronchiectasis and honeycombing in the earliest scans, even in asymptomatic patients, are related to mortality and progression later on.
MeSH term(s)	Humans ; Bronchiectasis ; Lung ; Lung Diseases, Interstitial/diagnostic imaging ; Lung Diseases, Interstitial/drug therapy ; Lung Diseases, Interstitial/epidemiology ; Prevalence ; Prognosis ; Tomography, X-Ray Computed ; Retrospective Studies
Language	English
Publishing date	2024-02-28
Publishing country	Spain
Document type	Observational Study ; Journal Article
ISSN	2173-5107
ISSN (online)	2173-5107
DOI	10.1016/j.rxeng.2023.03.006
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Orogenital Human Papillomavirus Infection and Vaccines: A Survey of High- and Low-Risk Genotypes Not Included in Vaccines.

Buttà, Michela / Serra, Nicola / Panzarella, Vera / Fasciana, Teresa Maria Assunta / Campisi, Giuseppina / Capra, Giuseppina

Vaccines

2023 Volume 11, Issue 9

Abstract: Knowledge of human papillomavirus transmission from the genital tract to the oral mucosa remains unsatisfactory, with poor and often inconsistent literature results. The increase in HPV-associated oral malignancies prompts further analysis of the ... ...

Abstract	Knowledge of human papillomavirus transmission from the genital tract to the oral mucosa remains unsatisfactory, with poor and often inconsistent literature results. The increase in HPV-associated oral malignancies prompts further analysis of the simultaneous detection of the virus in the two anatomical areas and on the identification of genotypes to be included in future vaccines. Therefore, in this retrospective study, we evaluated orogenital HPV concurrence, hrHPV, lrHPV and type-concordance in 337 samples, as well as the prevalence of the most common genotypes not included in HPV vaccines. Concurrence was found in 12.5% (31/248) of cases, hr-concordance in 61.3% (19/31) and lr-concordance in 12.9% (4/31). Finally, type-concordance was found in 32.3% (10/31) of concurrent infections. Regarding the identification of non-vaccine genotypes, the significantly prevalent genotypes in the anogenital area were HPV66 (12.6%,
Language	English
Publishing date	2023-09-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines11091466
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Article ; Online: Motives for alcohol use, risky drinking patterns and harm reduction practices among people who experience homelessness and alcohol dependence in Montreal.

Motta-Ochoa, Rossio / Incio-Serra, Natalia / Brulotte, Alexandre / Flores-Aranda, Jorge

Harm reduction journal

2023 Volume 20, Issue 1, Page(s) 22

Abstract: Background: People experiencing homelessness are disproportionately affected by harms related to alcohol use. Indeed, their alcohol dependence is associated with numerous physical and mental health problems along with strikingly high rates of alcohol- ... ...

Abstract	Background: People experiencing homelessness are disproportionately affected by harms related to alcohol use. Indeed, their alcohol dependence is associated with numerous physical and mental health problems along with strikingly high rates of alcohol-related mortality. Recent research has extensively examined alcohol use patterns among people experiencing homelessness in an effort to develop interventions and treatments for this problem. However, only a few studies have incorporated the perspectives of the individuals under study about their drinking or examined the ways in which they manage the associated harms. To bridge this gap, we conducted a qualitative study exploring the relation between the drinking motives, risky drinking patterns and harm reduction practices of a group of people (n = 34) experiencing homelessness in Montreal, Canada. Methods: The qualitative methods we used consisted of semi-structured interviews (n = 12) and focus groups (n = 2, with a total of 22 participants). The content of the collected data was then analyzed. Results: Participants identified their various motives for alcohol use (coping with painful memories, dealing with harsh living conditions, socializing/seeking a sense of belonging, enjoying themselves/having fun); their risky drinking patterns (binge drinking, mixing alcohol with drugs, non-beverage alcohol drinking, failing to keep sufficient alcohol on hand to prevent acute withdrawal, drinking in public settings); their harm reduction practices (planning how much to drink, keeping a supply of alcohol to prevent acute withdrawal, hiding to drink, concealing alcohol, drinking alone, drinking/hanging out with others, drinking non-beverage alcohol, and taking benzodiazepines, cocaine or other stimulant drugs); and the rationales underpinning their alcohol use and harm reduction practices. Conclusion: Associating the drinking motives of a group of study participants with their risky drinking patterns and harm reduction practices shed light on their rationales for alcohol use, yielding insights that could be used to better tailor policies and interventions to their needs.
MeSH term(s)	Humans ; Alcoholism/psychology ; Harm Reduction ; Alcohol Drinking/prevention & control ; Ill-Housed Persons ; Social Problems ; Motivation ; Ethanol
Chemical Substances	Ethanol (3K9958V90M)
Language	English
Publishing date	2023-02-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2146691-9
ISSN	1477-7517 ; 1477-7517
ISSN (online)	1477-7517
ISSN	1477-7517
DOI	10.1186/s12954-023-00757-2
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Article ; Online: Allelopathy in rice: a story of momilactones, kin recognition, and weed management.

Serra Serra, Núria / Shanmuganathan, Reshi / Becker, Claude

Journal of experimental botany

2021 Volume 72, Issue 11, Page(s) 4022–4037

Abstract: In the struggle to secure nutrient access and to outperform competitors, some plant species have evolved a biochemical arsenal with which they inhibit the growth or development of neighbouring plants. This process, known as allelopathy, exists in many of ...

Abstract	In the struggle to secure nutrient access and to outperform competitors, some plant species have evolved a biochemical arsenal with which they inhibit the growth or development of neighbouring plants. This process, known as allelopathy, exists in many of today's major crops, including rice. Rice synthesizes momilactones, diterpenoids that are released into the rhizosphere and inhibit the growth of numerous plant species. While the allelopathic potential of rice was recognized decades ago, many questions remain unresolved regarding the biosynthesis, exudation, and biological activity of momilactones. Here, we review current knowledge on momilactones, their role in allelopathy, and their potential to serve as a basis for sustainable weed management. We emphasize the gaps in our current understanding of when and how momilactones are produced and of how they act in plant cells, and outline what we consider the next steps in momilactone and rice allelopathy research.
MeSH term(s)	Allelopathy ; Diterpenes ; Lactones ; Oryza ; Rhizosphere
Chemical Substances	Diterpenes ; Lactones
Language	English
Publishing date	2021-02-13
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2976-2
ISSN	1460-2431 ; 0022-0957
ISSN (online)	1460-2431
ISSN	0022-0957
DOI	10.1093/jxb/erab084
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Hunting for

Cornella, C / Isidori, G / König, M / Liechti, S / Owen, P / Serra, N

The European physical journal. C, Particles and fields

2020 Volume 80, Issue 12, Page(s) 1095

Abstract: We investigate the possibility of indirectly constraining ... ...

Abstract	We investigate the possibility of indirectly constraining the
Language	English
Publishing date	2020-11-30
Publishing country	France
Document type	Journal Article
ZDB-ID	1459069-4
ISSN	1434-6052 ; 1434-6044
ISSN (online)	1434-6052
ISSN	1434-6044
DOI	10.1140/epjc/s10052-020-08674-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Arctic sea level variability from high-resolution model simulations and implications for the Arctic observing system

Lyu, Guokun / Serra, Nuno / Zhou, Meng / Stammer, Detlef

eISSN: 1812-0792

2022

Abstract: Two high-resolution model simulations are used to investigate the spatiotemporal variability of the Arctic Ocean sea level. The model simulations reveal barotropic sea level variability at periods of < 30 d, which is strongly captured by bottom pressure ... ...

Abstract	Two high-resolution model simulations are used to investigate the spatiotemporal variability of the Arctic Ocean sea level. The model simulations reveal barotropic sea level variability at periods of < 30 d, which is strongly captured by bottom pressure observations. The seasonal sea level variability is driven by volume exchanges with the Pacific and Atlantic oceans and the redistribution of the water by the wind. Halosteric effects due to river runoff and evaporation minus precipitation ice melting/formation also contribute in the marginal seas and seasonal sea ice extent regions. In the central Arctic Ocean, especially the Canadian Basin, the decadal halosteric effect dominates sea level variability. The study confirms that satellite altimetric observations and Gravity Recovery and Climate Experiment (GRACE) could infer the total freshwater content changes in the Canadian Basin at periods longer than 1 year, but they are unable to depict the seasonal and subseasonal freshwater content changes. The increasing number of profiles seems to capture freshwater content changes since 2007, encouraging further data synthesis work with a more complicated interpolation method. Further, in situ hydrographic observations should be enhanced to reveal the freshwater budget and close the gaps between satellite altimetry and GRACE, especially in the marginal seas.
Subject code	551
Language	English
Publishing date	2022-01-06
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Mathematical models in nursing research.

Rea, Teresa / Guillari, Assunta / Sergi, Consolato / Serra, Nicola

Journal of public health research

2020 Volume 9, Issue 4, Page(s) 1952

Abstract: This paper discusses the use of advanced mathematical tools in nursing research, such as mathematical models used in medicine for description and prediction of experimental tumor growth. They are rarely used in nursing research, but fortunately in the ... ...

Abstract	This paper discusses the use of advanced mathematical tools in nursing research, such as mathematical models used in medicine for description and prediction of experimental tumor growth. They are rarely used in nursing research, but fortunately in the last decade, their use is increased, mainly due to artificial intelligence and Big Data, with great benefits for further nursing development. Therefore, a strong interaction between nurses and mathematicians is needed to improve nursing research, and consequently, the nurses' performance in daily work.
Language	English
Publishing date	2020-12-10
Publishing country	Italy
Document type	Journal Article
ISSN	2279-9028
ISSN	2279-9028
DOI	10.4081/jphr.2020.1952
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