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  1. Article ; Online: World capital markets facing the first wave of COVID-19

    Angosto-Fernández Pedro Luis / Ferrández-Serrano Victoria

    Economics and Business Review, Vol 8, Iss 4, Pp 5-

    Traditional event study versus sensitivity to new cases

    2022  Volume 38

    Abstract: The aim of the paper is to analyse the impact of the new coronavirus on financial markets. The sample comprises returns from 80 countries, across all regions and incomes for the period known as the first wave. By combining event study methodology and ... ...

    Abstract The aim of the paper is to analyse the impact of the new coronavirus on financial markets. The sample comprises returns from 80 countries, across all regions and incomes for the period known as the first wave. By combining event study methodology and time series analysis of new COVID-19 cases it is found that the negative price effect is widespread but unequal across regions. It is also noted that the distribution of the impact is also uneven with a high concentration in the week after the first local case but especially in the weeks around the pandemic declaration. Finally, it has been shown at different levels how the markets most affected by the crisis are not necessarily the most sensitive to the virus.
    Keywords financial markets ; event study ; covid-19 ; coronavirus ; stock returns ; g01 ; g14 ; g15 ; f65 ; c32 ; Economics as a science ; HB71-74
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Respiratory Physiotherapy and Bronchiectasis.

    Alcaraz-Serrano, Victoria / Lee, Annemarie L / Gimeno-Santos, Elena

    Archivos de bronconeumologia

    2021  Volume 58, Issue 5, Page(s) 377–378

    MeSH term(s) Bronchiectasis/etiology ; Bronchiectasis/therapy ; Humans ; Physical Therapy Modalities
    Language Spanish
    Publishing date 2021-09-14
    Publishing country Spain
    Document type Editorial
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbres.2021.09.001
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  3. Article ; Online: Pseudomonas aeruginosa in Bronchiectasis.

    Fernández-Barat, Laia / Alcaraz-Serrano, Victoria / Amaro, Rosanel / Torres, Antoni

    Seminars in respiratory and critical care medicine

    2021  Volume 42, Issue 4, Page(s) 587–594

    Abstract: Pseudomonas ... ...

    Abstract Pseudomonas aeruginosa
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bronchiectasis/drug therapy ; Humans ; Persistent Infection ; Pseudomonas Infections/drug therapy ; Pseudomonas aeruginosa ; Quality of Life
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-07-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1183617-9
    ISSN 1098-9048 ; 1069-3424
    ISSN (online) 1098-9048
    ISSN 1069-3424
    DOI 10.1055/s-0041-1730921
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  4. Article ; Online: Reliability and Minimum Important Difference of Sputum Weight in Bronchiectasis.

    Herrero-Cortina, Beatriz / Alcaraz-Serrano, Victoria / Torres, Antoni / Polverino, Eva

    Respiratory care

    2020  Volume 65, Issue 10, Page(s) 1478–1487

    Abstract: Background: Despite the widespread use of sputum weight to assess the effect of airway clearance interventions, its psychometric properties have not been evaluated. The purpose of this ad hoc analysis was to determine the test-retest reliability of 24-h ...

    Abstract Background: Despite the widespread use of sputum weight to assess the effect of airway clearance interventions, its psychometric properties have not been evaluated. The purpose of this ad hoc analysis was to determine the test-retest reliability of 24-h sputum weight in clinically stable individuals with bronchiectasis. This study also aimed to estimate the minimum important difference of 24-h sputum weight after an airway clearance session in subjects with bronchiectasis.
    Methods: Sixty subjects were included in the 24-h test-retest cohort, 42 of whom were part of the airway clearance cohort. For the 24-h test-retest cohort, spontaneously expectorated sputum was collected over 24 h on 2 different days without any airway clearance interventions. For the airway clearance cohort, sputum expectoration was also collected during 3 airway clearance sessions and over the 24 h following these interventions. Intraclass correlation coefficient (ICC
    Results: The reliability was acceptable (ICC
    Conclusions: Multiple measurements should be considered to increase the agreement when sputum weight is used as an outcome measure for short periods in people with bronchiectasis. A reduction of 6.4 g (or 17% from baseline) in sputum collected during the 24 h after the airway clearance intervention may be considered the minimum important difference in people with bronchiectasis. (ClinicalTrials.gov registration NCT02392663; NCT01854788; NCT02614300.).
    MeSH term(s) Bronchiectasis ; Cough ; Humans ; Reproducibility of Results ; Respiratory Therapy ; Sputum
    Language English
    Publishing date 2020-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.07175
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  5. Article ; Online: Respiratory Muscle Training in Patients with Obstructive Sleep Apnoea: A Systematic Review and Meta-Analysis.

    Torres-Castro, Rodrigo / Solis-Navarro, Lilian / Puppo, Homero / Alcaraz-Serrano, Victoria / Vasconcello-Castillo, Luis / Vilaró, Jordi / Vera-Uribe, Roberto

    Clocks & sleep

    2022  Volume 4, Issue 2, Page(s) 219–229

    Abstract: Background: Effective treatments for obstructive sleep apnoea (OSA) include positive pressure, weight loss, oral appliances, surgery, and exercise. Although the involvement of the respiratory muscles in OSA is evident, the effect of training them to ... ...

    Abstract Background: Effective treatments for obstructive sleep apnoea (OSA) include positive pressure, weight loss, oral appliances, surgery, and exercise. Although the involvement of the respiratory muscles in OSA is evident, the effect of training them to improve clinical outcomes is not clear. We aimed to determine the effects of respiratory muscle training in patients with OSA. Methods: A systematic review was conducted in seven databases. Studies that applied respiratory muscle training in OSA patients were reviewed. Two independent reviewers analysed the studies, extracted the data and assessed the quality of evidence. Results: Of the 405 reports returned by the initial search, eight articles reporting on 210 patients were included in the data synthesis. Seven included inspiratory muscle training (IMT), and one included expiratory muscle training (EMT). Regarding IMT, we found significant improvement in Epworth sleepiness scale in −4.45 points (95%CI −7.64 to −1.27 points, p = 0.006), in Pittsburgh sleep quality index of −2.79 points (95%CI −4.19 to −1.39 points, p < 0.0001), and maximum inspiratory pressure of −29.56 cmH2O (95%CI −53.14 to −5.98 cmH2O, p = 0.01). However, the apnoea/hypopnea index and physical capacity did not show changes. We did not perform a meta-analysis of EMT due to insufficient studies. Conclusion: IMT improves sleepiness, sleep quality and inspiratory strength in patients with OSA.
    Language English
    Publishing date 2022-04-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2624-5175
    ISSN (online) 2624-5175
    DOI 10.3390/clockssleep4020020
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  6. Article: Pseudomonas aeruginosa in Bronchiectasis

    Fernández-Barat, Laia / Alcaraz-Serrano, Victoria / Amaro, Rosanel / Torres, Antoni

    Seminars in Respiratory and Critical Care Medicine

    (Bronchiectasis: Advances in Diagnosis and Treatment)

    2021  Volume 42, Issue 04, Page(s) 587–594

    Abstract: Pseudomonas aeruginosa (PA) in patients with bronchiectasis (BE) is associated with a poor outcome and quality of life, and its presence is considered a marker of disease severity. This opportunistic pathogen is known for its ability to produce biofilms ... ...

    Series title Bronchiectasis: Advances in Diagnosis and Treatment
    Abstract Pseudomonas aeruginosa (PA) in patients with bronchiectasis (BE) is associated with a poor outcome and quality of life, and its presence is considered a marker of disease severity. This opportunistic pathogen is known for its ability to produce biofilms on biotic or abiotic surfaces and to survive environmental stress exerted by antimicrobials, inflammation, and nutrient or oxygen depletion. The presence of PA biofilms has been linked to chronic respiratory infection in cystic fibrosis but not in BE. There is considerable inconsistency in the reported infection/eradication rates of PA and chronic PA. In addition, inadequate antimicrobial treatment may potentiate the progression from intermittent to chronic infection and also the emergence of antibiotic resistance. A better comprehension of the pathophysiology of PA infections and its implications for BE is urgently needed. This can drive improvements in diagnostic accuracy, can move us toward a new consensus definition of chronic infection, can better define the follow-up of patients at risk of PA, and can achieve more successful eradication rates. In addition, the new technological advances regarding molecular diagnostics, -omics, and biomarkers require us to reconsider our traditional concepts.
    Keywords bronchiectasis ; biofilm ; exacerbation ; microbiome
    Language English
    Publishing date 2021-07-14
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 1183617-9
    ISSN 1098-9048 ; 1069-3424
    ISSN (online) 1098-9048
    ISSN 1069-3424
    DOI 10.1055/s-0041-1730921
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  7. Article ; Online: Determining the most accurate 16S rRNA hypervariable region for taxonomic identification from respiratory samples.

    López-Aladid, Ruben / Fernández-Barat, Laia / Alcaraz-Serrano, Victoria / Bueno-Freire, Leticia / Vázquez, Nil / Pastor-Ibáñez, Roque / Palomeque, Andrea / Oscanoa, Patricia / Torres, Antoni

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 3974

    Abstract: 16S rRNA gene profiling, which contains nine hypervariable regions (V1-V9), is the gold standard for identifying taxonomic units by high-throughput sequencing. Microbiome studies combine two or more region sequences (usually V3-V4) to increase the ... ...

    Abstract 16S rRNA gene profiling, which contains nine hypervariable regions (V1-V9), is the gold standard for identifying taxonomic units by high-throughput sequencing. Microbiome studies combine two or more region sequences (usually V3-V4) to increase the resolving power for identifying bacterial taxa. We compare the resolving powers of V1-V2, V3-V4, V5-V7, and V7-V9 to improve microbiome analyses in sputum samples from patients with chronic respiratory diseases. DNA were isolated from 33 human sputum samples, and libraries were created using a QIASeq screening panel intended for Illumina platforms (16S/ITS; Qiagen Hilden, Germany). The analysis included a mock community as a microbial standard control (ZymoBIOMICS). We used the Deblur algorithm to identify bacterial amplicon sequence variants (ASVs) at the genus level. Alpha diversity was significantly higher for V1-V2, V3-V4, and V5-V7 compared with V7-V9, and significant compositional dissimilarities in the V1-V2 and V7-V9 analyses versus the V3-V4 and V5-V7 analyses. A cladogram confirmed these compositional differences, with the latter two being very similar in composition. The combined hypervariable regions showed significant differences when discriminating between the relative abundances of bacterial genera. The area under the curve revealed that V1-V2 had the highest resolving power for accurately identifying respiratory bacterial taxa from sputum samples. Our study confirms that 16S rRNA hypervariable regions provide significant differences for taxonomic identification in sputum. Comparing the taxa of microbial community standard control with the taxa samples, V1-V2 combination exhibits the most sensitivity and specificity. Thus, while third generation full-length 16S rRNA sequencing platforms become more available, the V1-V2 hypervariable regions can be used for taxonomic identification in sputum.
    MeSH term(s) Humans ; RNA, Ribosomal, 16S/genetics ; Sequence Analysis, DNA ; Bacteria ; Microbiota/genetics ; Respiratory System ; High-Throughput Nucleotide Sequencing
    Chemical Substances RNA, Ribosomal, 16S
    Language English
    Publishing date 2023-03-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-30764-z
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  8. Article ; Online: Association Between Viscoelastic Characteristics and Sputum Colour in Patients With Bronchiectasis.

    Alcaraz-Serrano, Victoria / Sanz-Fraile, Héctor / Bueno-Freire, Leticia / Farré, Ramón / Otero, Jorge / Vázquez, Nil / Rovira-Ribalta, Nona / Oscanoa, Patricia / Torres, Antoni / Fernández-Barat, Laia

    Archivos de bronconeumologia

    2023  Volume 59, Issue 6, Page(s) 406–408

    MeSH term(s) Humans ; Sputum ; Color ; Bronchiectasis ; Cough
    Language Spanish
    Publishing date 2023-02-25
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbres.2023.02.011
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  9. Article: Exacerbations and Changes in Physical Activity and Sedentary Behaviour in Patients with Bronchiectasis after 1 Year.

    Alcaraz-Serrano, Victoria / Arbillaga-Etxarri, Ane / Oscanoa, Patricia / Fernández-Barat, Laia / Bueno, Leticia / Amaro, Rosanel / Gimeno-Santos, Elena / Torres, Antoni

    Journal of clinical medicine

    2021  Volume 10, Issue 6

    Abstract: Background: Low physical activity and high sedentary behaviour in patients with bronchiectasis are associated with hospitalisation over one year. However, the factors associated with longitudinal changes in physical activity and sedentary behaviour have ...

    Abstract Background: Low physical activity and high sedentary behaviour in patients with bronchiectasis are associated with hospitalisation over one year. However, the factors associated with longitudinal changes in physical activity and sedentary behaviour have not been explored. We aimed to identify clinical and sociodemographic characteristics related to a change in physical activity and sedentary behaviour in patients with bronchiectasis after one year.
    Methods: This was a prospective observational study during which physical activity measurements were recorded using a SenseWear Armband for one week at baseline and at one year. At each assessment point, patients were classified as active or inactive (measured as steps per day) and as sedentary or not sedentary (measured as sedentary time).
    Results: 53 patients with bronchiectasis were analysed, and after one year, 18 (34%) had worse activity and sedentary levels. Specifically, 10 patients became inactive and sedentary. Multivariable analysis showed that the number of exacerbations during the follow-up period was the only outcome independently associated with change to higher inactivity and sedentary behaviour (odds ratio (OR), 2.19; 95% CI, 1.12 to 4.28).
    Conclusions: The number of exacerbations in patients with bronchiectasis was associated with changes in physical activity and sedentary behaviour. Exacerbation prevention may appear as a key factor in relation to physical activity and sedentary behaviour in patients with bronchiectasis.
    Language English
    Publishing date 2021-03-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10061190
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  10. Article ; Online: Airway clearance techniques and exercise in people with bronchiectasis: two different coins.

    Herrero-Cortina, Beatriz / Spinou, Arietta / Oliveira, Ana / O'Neill, Brenda / Jácome, Cristina / Dal Corso, Simone / Poncin, William / Muñoz, Gerard / Inal-Ince, Deniz / Alcaraz-Serrano, Victoria / Reychler, Gregory / Bellofiore, Angela / Posthumus, Annette / Chalmers, James D / Lee, Annemarie L

    The European respiratory journal

    2023  Volume 62, Issue 4

    MeSH term(s) Humans ; Numismatics ; Bronchiectasis ; Respiratory Therapy/methods ; Exercise
    Language English
    Publishing date 2023-10-12
    Publishing country England
    Document type Editorial
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.00741-2023
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