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  1. Book ; Online: Polymer-Based Biomaterials and Tissue Engineering

    Sabater i Serra, Roser / Serrano-Aroca, Ángel / Serrano-Aroca, Ángel

    2023  

    Keywords Medicine ; bioactive glass ; copper ; polyhydroxyalkanoates ; tissue engineering ; scaffolds ; parastomal hernia ; surgical mesh ; hernia repair ; prevention ; biocompatibility ; n/a ; polylactic acid ; copolymers ; catalysts ; polymer synthesis ; ring-opening polymerization ; medical application ; electrospun nanofibres ; nanocomposites ; polylactic acid (PLA) ; poly(ε-caprolactone) (PCL) ; halloysite nanotubes (HNTs) ; drug release ; release kinetic modelling ; nanoparticles ; rivastigmine ; intranasal application ; optimization ; quality by design ; polymer-ceramic composites ; hydroxyapatite ; collagen ; swelling capacity ; surface roughness ; wettability ; surface free energy ; nonwoven ; cardiovascular stent ; human endothelial cells ; CD31 ; polysaccharide ; carrageenan ; nanoparticle ; pulmonary drug delivery ; carbon-based nanocomposite ; conductive cell substrate ; semi-IPN hydrogel ; graphene nanosheets ; poly(3-hydroxybutyrate-co-3-hydroxyvalerate) ; polyvinyl alcohol
    Language English
    Size 1 electronic resource (190 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030382182
    ISBN 9783036582368 ; 3036582363
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Acrylate Polymers for Advanced Applications

    Serrano-Aroca, Ángel / Serrano-Aroca, Ángel / Deb, Sanjukta

    2020  

    Keywords Spectrum analysis, spectrochemistry, mass spectrometry ; Polymer chemistry
    Size 1 electronic resource (106 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021046491
    ISBN 9781789847116 ; 1789847117
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Antiviral Characterization of Advanced Materials: Use of Bacteriophage Phi 6 as Surrogate of Enveloped Viruses Such as SARS-CoV-2.

    Serrano-Aroca, Ángel

    International journal of molecular sciences

    2022  Volume 23, Issue 10

    Abstract: The bacteriophage phi 6 is a virus that belongs to a different Baltimore group than SARS-CoV-2 (group III instead of IV). However, it has a round-like shape and a lipid envelope like SARS-CoV-2, which render it very useful to be used as a surrogate of ... ...

    Abstract The bacteriophage phi 6 is a virus that belongs to a different Baltimore group than SARS-CoV-2 (group III instead of IV). However, it has a round-like shape and a lipid envelope like SARS-CoV-2, which render it very useful to be used as a surrogate of this infectious pathogen for biosafety reasons. Thus, recent antiviral studies have demonstrated that antiviral materials such as calcium alginate hydrogels, polyester-based fabrics coated with benzalkonium chloride (BAK), polyethylene terephthalate (PET) coated with BAK and polyester-based fabrics coated with cranberry extracts or solidified hand soap produce similar log reductions in viral titers of both types of enveloped viruses after similar viral contact times. Therefore, researchers with no access to biosafety level 3 facilities can perform antiviral tests of a broad range of biomaterials, composites, nanomaterials, nanocomposites, coatings and compounds against the bacteriophage phi 6 as a biosafe viral model of SARS-CoV-2. In fact, this bacteriophage has been used as a surrogate of SARS-CoV-2 to test a broad range of antiviral materials and compounds of different chemical natures (polymers, metals, alloys, ceramics, composites, etc.) and forms (films, coatings, nanomaterials, extracts, porous supports produced by additive manufacturing, etc.) during the current pandemic. Furthermore, this biosafe viral model has also been used as a surrogate of SARS-CoV-2 and other highly pathogenic enveloped viruses such as Ebola and influenza in a wide range of biotechnological applications.
    MeSH term(s) Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Bacteriophage phi 6 ; COVID-19 ; Humans ; Plant Extracts/pharmacology ; Polyesters/pharmacology ; SARS-CoV-2 ; Virus Replication
    Chemical Substances Antiviral Agents ; Plant Extracts ; Polyesters
    Language English
    Publishing date 2022-05-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23105335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Special Issue: "Polymer-Based Biomaterials and Tissue Engineering".

    Sabater I Serra, Roser / Serrano-Aroca, Ángel

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 14

    Abstract: Polymers in the form of films, fibers, nano- and microspheres, composites, and porous supports are promising biomaterials for a wide range of advanced biomedical applications: wound healing, controlling drug delivery, anti-cancer therapy, biosensors, ... ...

    Abstract Polymers in the form of films, fibers, nano- and microspheres, composites, and porous supports are promising biomaterials for a wide range of advanced biomedical applications: wound healing, controlling drug delivery, anti-cancer therapy, biosensors, stem cell therapy, and tissue engineering [...].
    Language English
    Publishing date 2023-07-10
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16144923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Next generation meshes for hernia repair: Polypropylene meshes coated with antimicrobial benzalkonium chloride induced proliferative activity of fibroblasts.

    Serrano-Aroca, Ángel / Cano-Vicent, Alba / Tuñón-Molina, Alberto / Pous-Serrano, Salvador

    Heliyon

    2024  Volume 10, Issue 1, Page(s) e24237

    Abstract: Hernia repair is one of the most frequently performed world-wide surgical procedures in which hernia meshes are becoming increasingly used. Polypropylene (PP) mesh implants reduce the risk of recurrence and post-operative pain, although many other risks ... ...

    Abstract Hernia repair is one of the most frequently performed world-wide surgical procedures in which hernia meshes are becoming increasingly used. Polypropylene (PP) mesh implants reduce the risk of recurrence and post-operative pain, although many other risks are associated with it, such as bacterial infection. In this study we developed PP meshes coated with the well-known antimicrobial compound, benzalkonium chloride (BAK) by dip-coating. Several dilutions (40, 20, 30, 10, 7.5, 5, 2.5, 1, 0.5, 0.1 and 0.05 %
    Language English
    Publishing date 2024-01-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Tiger Nut Milk's Antiviral Properties against Enveloped and Non-Enveloped Viruses: Effect of Concentration and Adding Sugar.

    Tuñón-Molina, Alberto / Cano-Vicent, Alba / Serrano-Aroca, Ángel

    International journal of molecular sciences

    2023  Volume 24, Issue 15

    Abstract: The global COVID-19 pandemic has warned scientists of the requirement to look for new antimicrobial compounds to prevent infection by this type of viral pathogen. Natural compounds are becoming a promising avenue of research thanks to their renewable, ... ...

    Abstract The global COVID-19 pandemic has warned scientists of the requirement to look for new antimicrobial compounds to prevent infection by this type of viral pathogen. Natural compounds are becoming a promising avenue of research thanks to their renewable, biodegradable, and non-toxic properties. In this work, tiger nut milk's (TNM) antiviral properties, with and without sugar, were studied against enveloped and non-enveloped viruses. The antiviral properties of TNM were evaluated at different concentrations. The antiviral tests showed that TNM is antiviral against the enveloped bacteriophage phi 6, which is commonly used as a surrogate for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), although it did not have any antiviral effect against the non-enveloped bacteriophage MS2. We also found that adding sugar to this natural drink can improve its antiviral properties against enveloped viruses and render it antiviral against non-enveloped viruses like bacteriophage MS2. The antiviral activity of TNM depends on the TNM concentration. TNM is a natural bioproduct that could help to fight against viral infections and protect against a wide range of viral illnesses. These results confirm that the typical sweetened drink made from tiger nut extract and sugar (known as horchata in Spain) possesses broad-spectrum antiviral properties.
    MeSH term(s) Humans ; Animals ; Antiviral Agents/pharmacology ; Milk ; Sugars ; Pandemics ; COVID-19 ; SARS-CoV-2
    Chemical Substances Antiviral Agents ; Sugars
    Language English
    Publishing date 2023-07-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241512018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: On the association between COVID-19 vaccination levels and incidence and lethality rates at a regional scale in Spain.

    Briz-Redón, Álvaro / Serrano-Aroca, Ángel

    Stochastic environmental research and risk assessment : research journal

    2022  Volume 36, Issue 9, Page(s) 2941–2948

    Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19), has led to the deepest global health and economic crisis of the current century. This dramatic situation has forced the public health ... ...

    Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19), has led to the deepest global health and economic crisis of the current century. This dramatic situation has forced the public health authorities and pharmaceutical companies to develop anti-COVID-19 vaccines in record time. Currently, almost 80% of the population are vaccinated with the required number of doses in Spain. Thus, in this paper, COVID-19 incidence and lethality rates are analyzed through a segmented spatio-temporal regression model that allows studying if there is an association between a certain vaccination level and a change (in mean) in either the incidence or the lethality rates. Spatial dependency is included by considering the Besag-York-Mollié model, whereas natural cubic splines are used for capturing the temporal structure of the data. Lagged effects between the exposure and the outcome are also taken into account. The results suggest that COVID-19 vaccination has not allowed yet (as of September 2021) to observe a consistent reduction in incidence levels at a regional scale in Spain. In contrast, the lethality rates have displayed a declining tendency which has associated with vaccination levels above 50%.
    Language English
    Publishing date 2022-01-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1481263-0
    ISSN 1436-3259 ; 1435-151X ; 1436-3240 ; 0931-1955
    ISSN (online) 1436-3259 ; 1435-151X
    ISSN 1436-3240 ; 0931-1955
    DOI 10.1007/s00477-021-02166-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Frontiers in Antimicrobial Materials.

    Serrano-Aroca, Ángel / Tambuwala, Murtaza M / Birkett, Martin

    International journal of molecular sciences

    2022  Volume 23, Issue 14

    Abstract: The aim of this Special Edition is to highlight the exponential work performed in the field of antimicrobial material research from the beginning of the current COVID-19 pandemic [ ... ]. ...

    Abstract The aim of this Special Edition is to highlight the exponential work performed in the field of antimicrobial material research from the beginning of the current COVID-19 pandemic [...].
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents/pharmacology ; Anti-Infective Agents/therapeutic use ; COVID-19/drug therapy ; Humans ; Pandemics
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents
    Language English
    Publishing date 2022-07-21
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23148047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: On the association between COVID-19 vaccination levels and incidence and lethality rates at a regional scale in Spain

    Briz-Redón, Álvaro / Serrano-Aroca, Ángel

    Stochastic environmental research and risk assessment. 2022 Sept., v. 36, no. 9

    2022  

    Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19), has led to the deepest global health and economic crisis of the current century. This dramatic situation has forced the public health ... ...

    Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19), has led to the deepest global health and economic crisis of the current century. This dramatic situation has forced the public health authorities and pharmaceutical companies to develop anti-COVID-19 vaccines in record time. Currently, almost 80% of the population are vaccinated with the required number of doses in Spain. Thus, in this paper, COVID-19 incidence and lethality rates are analyzed through a segmented spatio-temporal regression model that allows studying if there is an association between a certain vaccination level and a change (in mean) in either the incidence or the lethality rates. Spatial dependency is included by considering the Besag–York–Mollié model, whereas natural cubic splines are used for capturing the temporal structure of the data. Lagged effects between the exposure and the outcome are also taken into account. The results suggest that COVID-19 vaccination has not allowed yet (as of September 2021) to observe a consistent reduction in incidence levels at a regional scale in Spain. In contrast, the lethality rates have displayed a declining tendency which has associated with vaccination levels above 50%.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; death ; economic crises ; models ; public health ; regression analysis ; research ; risk assessment ; vaccination ; Spain
    Language English
    Dates of publication 2022-09
    Size p. 2941-2948.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ZDB-ID 1481263-0
    ISSN 1436-3259 ; 1435-151X ; 1436-3240 ; 0931-1955
    ISSN (online) 1436-3259 ; 1435-151X
    ISSN 1436-3240 ; 0931-1955
    DOI 10.1007/s00477-021-02166-y
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: A city-level analysis of PM

    Briz-Redón, Álvaro / Belenguer-Sapiña, Carolina / Serrano-Aroca, Ángel

    Journal of environmental health science & engineering

    2022  Volume 20, Issue 1, Page(s) 395–403

    Language English
    Publishing date 2022-01-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2756287-6
    ISSN 2052-336X
    ISSN 2052-336X
    DOI 10.1007/s40201-022-00786-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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