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  1. AU="Shackleford, I M"
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  1. Article ; Online: Activ C cervical disc replacement for myelopathy.

    McGonagle, L / Cadman, S / Chitgopkar, S D / Canavan, L / O'Malley, M / Shackleford, I M

    Journal of craniovertebral junction & spine

    2012  Volume 2, Issue 2, Page(s) 82–85

    Abstract: Background: Cervical disc replacement is becoming an increasingly popular treatment option for cervical myelopathy. It retains motion at the affected segment, unlike anterior cervical discectomy and fusion. The aim of this study is to assess the ... ...

    Abstract Background: Cervical disc replacement is becoming an increasingly popular treatment option for cervical myelopathy. It retains motion at the affected segment, unlike anterior cervical discectomy and fusion. The aim of this study is to assess the outcomes of a series of patients who underwent Activ C disc replacement for cervical myelopathy.
    Materials and methods: A series of patients at the above Trust with clinical and radiological evidence of cervical myelopathy who were suitable for cervical disc replacement from 2007 to 2009 were included. Implants were inserted by one of two consultant surgeons {IMS, MO'M}. Patients were assessed preoperatively and at six, 12 and 24 months, postoperatively, with a visual analogue score (VAS) for neck and arm pain severity and frequency, the Neck Disability Index questionnaire (NDI) and the Centre for Epidemiologic Studies Depression questionnaire (CES-D).
    Results: Ten patients underwent surgery between May 2007 and July 2009, 6 women, and 4 men. Average age was 54 years (40-64). Disc levels replaced were: four at C4-5; eight at C5-6; seven at C6-7. Three patients had one disc replaced, five patients had two discs replaced, and two patients had three discs replaced. The VAS for neck pain improved from 5.9 pre-operatively to 1.4-24 months postoperatively and the VAS arm pain improved from 5.4 to 2.6. The NDI improved from 51% preoperatively to 26.8% at 24 months postoperatively. The CES-D showed a slight increase from 19.5 preoperatively to 21.7 at 24 months, postoperatively.
    Conclusion: Cervical decompression and disc replacement improves pain and function in patients with cervical myelopathy. This benefit is maintained at 24 months post op, with no cases requiring revision.
    Language English
    Publishing date 2012-10-18
    Publishing country India
    Document type Journal Article
    ZDB-ID 2573344-8
    ISSN 0976-9285 ; 0974-8237
    ISSN (online) 0976-9285
    ISSN 0974-8237
    DOI 10.4103/0974-8237.100062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A case report of a spinal epidural haematoma associated with warfarin therapy.

    Prasad, S S / O'Malley, M / Machani, B / Shackleford, I M

    Annals of the Royal College of Surgeons of England

    2003  Volume 85, Issue 4, Page(s) 277–278

    Abstract: Spinal epidural haematoma is an uncommon, but recognised, clinical entity that needs emergency management. The association of spinal epidural haematomata with warfarin therapy has been described and, in 1956, Alderman stated that this diagnosis should be ...

    Abstract Spinal epidural haematoma is an uncommon, but recognised, clinical entity that needs emergency management. The association of spinal epidural haematomata with warfarin therapy has been described and, in 1956, Alderman stated that this diagnosis should be entertained in any patient receiving anticoagulants presenting with low back pain or sciatic pain. The purpose of this case report is to increase the awareness of this entity among medical personnel and to stress the urgency of management.
    MeSH term(s) Anticoagulants/adverse effects ; Emergencies ; Female ; Hematoma, Epidural, Cranial/chemically induced ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Warfarin/adverse effects
    Chemical Substances Anticoagulants ; Warfarin (5Q7ZVV76EI)
    Language English
    Publishing date 2003-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/003588403766275024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: An assessment of the POSSUM system in orthopaedic surgery.

    Mohamed, K / Copeland, G P / Boot, D A / Casserley, H C / Shackleford, I M / Sherry, P G / Stewart, G J

    The Journal of bone and joint surgery. British volume

    2002  Volume 84, Issue 5, Page(s) 735–739

    Abstract: We describe the development and validation of a scoring system for auditing orthopaedic surgery. It is a minor modification of the POSSUM scoring system widely used in general surgery. The orthopaedic POSSUM system which we have developed gives ... ...

    Abstract We describe the development and validation of a scoring system for auditing orthopaedic surgery. It is a minor modification of the POSSUM scoring system widely used in general surgery. The orthopaedic POSSUM system which we have developed gives predictions for mortality and morbidity which correlate well with the observed rates in a sample of 2326 orthopaedic operations over a period of 12 months.
    MeSH term(s) Humans ; Orthopedic Procedures/mortality ; Outcome Assessment (Health Care) ; ROC Curve ; Severity of Illness Index
    Language English
    Publishing date 2002-07-10
    Publishing country England
    Document type Journal Article ; Validation Studies
    ZDB-ID 220626-2
    ISSN 2044-5377 ; 0301-620X ; 0447-9076
    ISSN (online) 2044-5377
    ISSN 0301-620X ; 0447-9076
    DOI 10.1302/0301-620x.84b5.12626
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: In vivo stress measurement can predict pain on discography.

    McNally, D S / Shackleford, I M / Goodship, A E / Mulholland, R C

    Spine

    1996  Volume 21, Issue 22, Page(s) 2580–2587

    Abstract: Study design: An in vivo experimental investigation of internal disc mechanics and discogenic pain.: Objectives: To test the hypotheses: 1) The pattern of internal loading of intervertebral discs in vivo is similar to that measured previously in ... ...

    Abstract Study design: An in vivo experimental investigation of internal disc mechanics and discogenic pain.
    Objectives: To test the hypotheses: 1) The pattern of internal loading of intervertebral discs in vivo is similar to that measured previously in vitro; 2) stress concentrations also are found in clinically degenerate discs in vivo; and stress concentrations are associated with discogenic pain.
    Summary of background data: Stress concentrations corresponding to potentially painful loading patterns of the intervertebral disc and endplate have been observed in vitro.
    Methods: The distribution of stress within the lumbar intervertebral discs of patients with chronic discogenic pain was measured using stress profilometry. The severity of their pain was assessed using provocative discography.
    Results: Discogenic pain was found to be associated with anomalous loading of the posterolateral anulus (P < 0.001) and nucleus (P < 0.01). Painful discs were found to have a 38% wider posterolateral anulus (P < 0.023) than painless discs and to have a 63% lower mean nuclear stress (P < 0.017).
    Conclusions: Stress profilometry is an effective investigation of the mechanics of intervertebral discs in vivo. Discogenic pain is caused by changes in the pattern of loading of the posterolateral anulus or nucleus pulposus.
    MeSH term(s) Adult ; Humans ; Intervertebral Disc/pathology ; Intervertebral Disc/physiopathology ; Magnetic Resonance Imaging ; Middle Aged ; Pain/pathology ; Pain/physiopathology ; Spinal Diseases/pathology ; Spinal Diseases/physiopathology ; Stress, Mechanical
    Language English
    Publishing date 1996-11-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 752024-4
    ISSN 1528-1159 ; 0362-2436
    ISSN (online) 1528-1159
    ISSN 0362-2436
    DOI 10.1097/00007632-199611150-00007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1305: Show issues Location:
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  5. Article: Automated percutaneous lumbar discectomy. An outcome study.

    Grevitt, M P / McLaren, A / Shackleford, I M / Mulholland, R C

    The Journal of bone and joint surgery. British volume

    1995  Volume 77, Issue 4, Page(s) 626–629

    Abstract: We treated 137 patients with symptomatic lumbar disc prolapse by automated percutaneous lumbar discectomy (APLD). Seventeen (12%) required further operation. At a mean follow-up of 55 months, the success rate was 45%. Of those who had APLD alone, 52% ... ...

    Abstract We treated 137 patients with symptomatic lumbar disc prolapse by automated percutaneous lumbar discectomy (APLD). Seventeen (12%) required further operation. At a mean follow-up of 55 months, the success rate was 45%. Of those who had APLD alone, 52% were graded as either excellent or good. In this group, 76% were employed, and the mean Oswestry score was 28.2%. One-third of those patients initially rated as successful had deterioration in symptoms and increased disability from back pain. The Short Form 36 health survey questionnaire revealed that these patients had a chronic ill-health profile.
    MeSH term(s) Adolescent ; Adult ; Diskectomy, Percutaneous ; Female ; Health Status ; Humans ; Intervertebral Disc Displacement/surgery ; Lumbar Vertebrae ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 1995-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 220626-2
    ISSN 2044-5377 ; 0301-620X ; 0447-9076
    ISSN (online) 2044-5377
    ISSN 0301-620X ; 0447-9076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Graf stabilisation system: early results in 50 patients.

    Grevitt, M P / Gardner, A D / Spilsbury, J / Shackleford, I M / Baskerville, R / Pursell, L M / Hassaan, A / Mulholland, R C

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

    1995  Volume 4, Issue 3, Page(s) 169–75; discussion 135

    Abstract: The results of the first 50 consecutive patients using the Graf stabilisation system are presented. The average age of the patients was 41 years; there were 32 women and 18 men in the group. All patients suffered from intractable symptomatic degenerative ...

    Abstract The results of the first 50 consecutive patients using the Graf stabilisation system are presented. The average age of the patients was 41 years; there were 32 women and 18 men in the group. All patients suffered from intractable symptomatic degenerative disc disease which could be localised to one or more levels. All patients gave a history of chronic back pain, but the mean period of severe disability was 24 months. The mean preoperative disability score (Oswestry questionnaire) was 59%. The average period of follow-up was 24 months (range 19-36 months). At the latest review, the mean disability score was 31%. The clinical results were classified as "excellent" or "good" in 72% of patients, "fair" in 10%, "the same" in 16% and "worse" in 2%. All but three patients felt that surgery was worthwhile. The results have not deteriorated over the period of follow-up.
    MeSH term(s) Adolescent ; Adult ; Aged ; Bone Screws ; Female ; Follow-Up Studies ; Humans ; Internal Fixators ; Intervertebral Disc Displacement/complications ; Intervertebral Disc Displacement/diagnostic imaging ; Intervertebral Disc Displacement/surgery ; Low Back Pain/diagnostic imaging ; Low Back Pain/etiology ; Low Back Pain/surgery ; Lumbar Vertebrae/diagnostic imaging ; Lumbar Vertebrae/surgery ; Male ; Middle Aged ; Postoperative Complications ; Radiography ; Spinal Fusion/instrumentation
    Language English
    Publishing date 1995
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1115375-1
    ISSN 1432-0932 ; 0940-6719
    ISSN (online) 1432-0932
    ISSN 0940-6719
    DOI 10.1007/bf00298241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3437: Show issues Location:
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