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  1. Book ; Online: RNA Viruses Infection

    Shah, Yogendra

    2022  

    Keywords Infectious & contagious diseases ; Clinical & internal medicine
    Language English
    Size 1 electronic resource (162 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030377432
    ISBN 9781803556680 ; 1803556684
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Molecular Epidemiology Study of Mycobacterium Tuberculosis Complex

    Shah, Yogendra

    2021  

    Keywords Respiratory medicine ; chemotherapy, quality of life, imaging, behçet's disease, aneurysm, molecular methods
    Language English
    Size 1 electronic resource (120 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030645505
    ISBN 9781839681011 ; 1839681012
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Some RNA Viruses

    Shah, Yogendra / Abuelzein, Eltayb

    2021  

    Keywords Infectious & contagious diseases
    Size 1 electronic resource (120 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021046648
    ISBN 9781839629273 ; 1839629274
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Protect elephants from tuberculosis.

    Shah, Yogendra / Paudel, Sarad

    Science (New York, N.Y.)

    2021  Volume 374, Issue 6569, Page(s) 832–833

    MeSH term(s) Animals ; Elephants ; Epidemiological Monitoring ; Mycobacterium bovis ; Mycobacterium tuberculosis ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology ; Tuberculosis/prevention & control ; Tuberculosis/veterinary
    Language English
    Publishing date 2021-11-11
    Publishing country United States
    Document type Letter
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.abm5609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ending tuberculosis by 2030: understanding the transmission.

    Pandey, Basu Dev / Ngwe Tun, Mya Myat / Shah, Yogendra / Suzuki, Yasuhiko / Morita, Kouichi

    The Lancet regional health. Western Pacific

    2023  Volume 38, Page(s) 100851

    Language English
    Publishing date 2023-07-13
    Publishing country England
    Document type Journal Article
    ISSN 2666-6065
    ISSN (online) 2666-6065
    DOI 10.1016/j.lanwpc.2023.100851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Forty years (1980-2019) of visceral leishmaniasis in Nepal: trends and elimination challenges.

    Pandey, Kishor / Dumre, Shyam Prakash / Shah, Yogendra / Acharya, Bipin Kumar / Khanal, Laxman / Pyakurel, Uttam Raj / Kaneko, Osamu / Pandey, Basu Dev

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2023  Volume 117, Issue 6, Page(s) 460–469

    Abstract: Background: Visceral leishmaniasis (VL) is an important re-emerging neglected tropical disease associated with poverty. Despite the elimination initiative started in 2005, VL cases have been expanding into geographic areas in Nepal. The present study ... ...

    Abstract Background: Visceral leishmaniasis (VL) is an important re-emerging neglected tropical disease associated with poverty. Despite the elimination initiative started in 2005, VL cases have been expanding into geographic areas in Nepal. The present study aims at exploring the trends of VL from 1980 to 2019.
    Methods: This retrospective analysis covers 40 y of VL cases reported by the Epidemiology Diseases Control Division, Nepal. Subgroup analyses for annual incidence were performed by age, sex, seasons, districts and provinces, and VL cases were visualized on in-country maps.
    Results: A total of 34 564 cases and 584 deaths of VL were reported during 1980-2019. VL persistently increased until 2006 and was reported from all seven provinces of the country. The highest number of confirmed cases (n=2229) was reported in 2003 and the lowest (n=60) in 1983. VL cases expanded from 12 to 23 endemic districts. The key components of the VL elimination program are early diagnosis; enhanced surveillance; integrated vector management; social mobilization; research and treatment.
    Conclusions: Expansion of VL towards the hilly and mountain regions of Nepal has posed challenges to the elimination program. Urgent VL control measures are required to achieve the elimination goals.
    MeSH term(s) Humans ; Leishmaniasis, Visceral/epidemiology ; Leishmaniasis, Visceral/prevention & control ; Nepal/epidemiology ; Retrospective Studies ; Incidence ; Seasons ; Leishmania donovani
    Language English
    Publishing date 2023-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1093/trstmh/trad001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Insights into transmission dynamics of Mycobacterium tuberculosis complex in Nepal.

    Shah, Yogendra / Paudel, Sarad / Pandey, Kishor / Gupta, Govind Prasad / Solo, Eddie Samuneti / Joshi, Jagadish / Pant, Dhan Kumar / Pandey, Basu Dev

    Tropical medicine and health

    2022  Volume 50, Issue 1, Page(s) 8

    Abstract: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis complex (MTBC) in humans and animals. Numbers of multi drug resistance TB (MDR-TB), extrapulmonary TB (EPTB) and zoonotic TB cases are increasingly being reported every year ... ...

    Abstract Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis complex (MTBC) in humans and animals. Numbers of multi drug resistance TB (MDR-TB), extrapulmonary TB (EPTB) and zoonotic TB cases are increasingly being reported every year in Nepal posing a major public health problem. Therefore, the Government of Nepal should act immediately to strengthen the screening facilities across the country to be able to identify and treat the TB infected patients as well as detect zoonotic TB in animal species. Endorsement of One Health Act by the Government of Nepal is an opportunity to initiate the joint programs for TB surveillance among human and animal species using one health approach to reduce the TB burden in Nepal.
    Language English
    Publishing date 2022-01-11
    Publishing country Japan
    Document type Letter
    ZDB-ID 2209835-5
    ISSN 1349-4147 ; 1348-8945
    ISSN (online) 1349-4147
    ISSN 1348-8945
    DOI 10.1186/s41182-022-00400-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Detection of virus-neutralising antibodies and associated factors against rabies in the vaccinated household dogs of Kathmandu Valley, Nepal.

    Rimal, Shikha / Ojha, Krishna Chandra / Chaisowwong, Warangkhana / Shah, Yogendra / Pant, Dhan Kumar / Sirimalaisuwan, Anucha

    PloS one

    2020  Volume 15, Issue 4, Page(s) e0231967

    Abstract: Background: Rabies is a vaccine-preventable neglected tropical viral zoonosis. It occurs worldwide, creating a very heavy burden in many developing countries, including Nepal. Dogs are the principle vector for the transmission of this disease in urban ... ...

    Abstract Background: Rabies is a vaccine-preventable neglected tropical viral zoonosis. It occurs worldwide, creating a very heavy burden in many developing countries, including Nepal. Dogs are the principle vector for the transmission of this disease in urban areas. Vaccination is the most important preventive measure in areas where dogs are the principle source of infection. This study was conducted with the aim of detecting virus-neutralising antibodies and associated factors against rabies in vaccinated household dogs of Kathmandu valley.
    Methods: Blood samples were collected from 110 vaccinated pet dogs in Kathmandu, Bhaktapur, and Lalitpur districts of Nepal. The samples were taken to the laboratory of the National Zoonosis and Food Hygiene Research Center where serum was separated. An indirect immune-enzymatic assay (PlateliaTM Rabies II kit ad usum Veterinarium, Biorad, China) was used for the detection of rabies virus anti-glycoprotein antibodies in the dog serum samples following the manufacturer's recommendations and instructions. Optical density values for unknown samples were compared with the positive sera titers in quantification tests obtained after a direct reading on the standard curve. Results were expressed as equivalent units per ml (EU/ml).
    Findings: Of the total samples, 89.09% exceeded the required seroconversion level (≥ 0.5 EU/ml); another 9.09% did not reach the seroconversion level (0.125-0.5 EU/ml); and 1.81% had undetectable seroconversion levels (<0.125 EU/ml) suggesting that the animal had not seroconverted according to the PLATELIA™ RABIES II test. Only one factor, the condition under which the dog was kept, was significantly associated with the antibody titer level. No association was found for any of the other factors included in the study.
    Interpretation: Vaccination is the most effective measure for prevention and control of rabies. The locally manufactured brand of vaccine, which is available in Nepal, is potent enough to generate a sufficient amount of protective antibodies, equal to international brands.
    MeSH term(s) Animals ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; Dog Diseases/pathology ; Dog Diseases/prevention & control ; Dog Diseases/virology ; Dogs ; Nepal ; Rabies/pathology ; Rabies/prevention & control ; Rabies Vaccines/immunology ; Rabies virus/immunology ; Vaccination
    Chemical Substances Antibodies, Neutralizing ; Antibodies, Viral ; Rabies Vaccines
    Keywords covid19
    Language English
    Publishing date 2020-04-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0231967
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Critical phase among patients with dengue fever during the 2010 outbreak in Nepal.

    Pun, Sher Bahadur / Shah, Yogendra

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2013  Volume 107, Issue 9, Page(s) 598–600

    Abstract: Background: Dengue virus infection has become an increasingly serious threat to public health in Nepal. Detection and/or serotyping of dengue virus has been reported in the past; however, little is known about the critical phase among dengue patients in ...

    Abstract Background: Dengue virus infection has become an increasingly serious threat to public health in Nepal. Detection and/or serotyping of dengue virus has been reported in the past; however, little is known about the critical phase among dengue patients in Nepal.
    Methods: Rapid immunochromatographic tests and reverse transcription PCR (RT-PCR) were performed in order to diagnosis dengue fever. Ultrasonographic and chest radiography were used to identify the plasma leakage phase.
    Results: Of the total 264 patients with dengue, 8.7% (23/264) were admitted during the critical phase; 82.6% (19/23) of the patients were between 20 and 44 years of age.
    Conclusion: Physicians need to be vigilant and attentive to young adult patients with dengue fever.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Child ; Dengue/diagnosis ; Dengue/epidemiology ; Disease Outbreaks ; Female ; Humans ; Male ; Middle Aged ; Nepal/epidemiology ; Reverse Transcriptase Polymerase Chain Reaction ; Serotyping ; Young Adult
    Language English
    Publishing date 2013-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1093/trstmh/trt061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Molecular and Entomological Characterization of 2023 Dengue Outbreak in Dhading District, Central Nepal.

    Rimal, Sandesh / Shrestha, Sabin / Paudel, Sunita Wagle / Shah, Yogendra / Bhandari, Govinda / Pandey, Kishor / Kharbuja, Anjana / Kapandji, Merveille / Gautam, Ishan / Bhujel, Rajshree / Takamatsu, Yuki / Bhandari, Rudramani / Klungthong, Chonticha / Shrestha, Sanjaya Kumar / Fernandez, Stefan / Malavige, Gathsaurie Neelika / Pandey, Basu Dev / Urano, Takeshi / Morita, Kouichi /
    Ngwe Tun, Mya Myat / Dumre, Shyam Prakash

    Viruses

    2024  Volume 16, Issue 4

    Abstract: In 2023, Nepal faced its second largest dengue outbreak ever, following a record-breaking number of dengue cases in 2022, characterized by the expansion of infections into areas of higher altitudes. However, the characteristics of the 2023 circulating ... ...

    Abstract In 2023, Nepal faced its second largest dengue outbreak ever, following a record-breaking number of dengue cases in 2022, characterized by the expansion of infections into areas of higher altitudes. However, the characteristics of the 2023 circulating dengue virus (DENV) and the vector density remain poorly understood. Therefore, we performed DENV serotyping, clinical and laboratory assessment, and entomological analysis of the 2023 outbreak in central Nepal. A total of 396 fever cases in Dhading hospital suspected of being DENV positive were enrolled, and blood samples were collected and tested by different techniques including PCR. Of these, 278 (70.2%) had confirmed DENV infection. Multiple serotypes (DENV-1, -2, and -3) were detected. DENV-2 (97.5%) re-emerged after six years in Dhading while DENV-3 was identified for the first time. Dengue inpatients had significantly higher frequency of anorexia, myalgia, rash, diarrhea, nausea, vomiting, abdominal pain, and thrombocytopenia (
    MeSH term(s) Nepal/epidemiology ; Dengue/epidemiology ; Dengue/virology ; Humans ; Dengue Virus/genetics ; Dengue Virus/classification ; Dengue Virus/isolation & purification ; Disease Outbreaks ; Animals ; Aedes/virology ; Male ; Female ; Mosquito Vectors/virology ; Adult ; Serogroup ; Adolescent ; Middle Aged ; Young Adult ; Child ; Serotyping ; Child, Preschool ; Phylogeny
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16040594
    Database MEDical Literature Analysis and Retrieval System OnLINE

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