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  1. Article ; Online: COVID-19 immunization phase; Acceptance & understandings about the vaccine. Shagufta Nesar

    Shagufta Nesar / Kiran Rafiq / Shaheen Parveen / Tayabba Mumtaz

    International Journal of Endorsing Health Science Research, Vol 9, Iss 4, Pp 426-

    2021  Volume 430

    Abstract: Background: In the current scenario of global immunization against Coronavirus, people do have an uncertain thought regarding the efficacy and effects of the vaccine. The purpose of this study was to assess the knowledge, awareness, and acceptability of ... ...

    Abstract Background: In the current scenario of global immunization against Coronavirus, people do have an uncertain thought regarding the efficacy and effects of the vaccine. The purpose of this study was to assess the knowledge, awareness, and acceptability of vaccines among the general population of Karachi. Methodology: For the purpose of the study, literature focusing on the knowledge, awareness, and acceptance regarding COVID-19 immunization was reviewed. Google Scholar, PubMed, Research Gate, and Scopus were searched using the keywords COVID-19, non-pharmaceutical Interventions, immunization-related knowledge, awareness, and acceptance. A pilot study was designed to demonstrate the COVID-19 immunization understanding and acceptability. Results: Low rate of acceptability for getting vaccinated is observed in the local population. Most perceptions indicated vaccines to be not healthy, harmful, and life-threatening. Conclusion: The current situation of fast-spreading of the virus and the non-acceptance of vaccines is highly alarming for community and health authorities and demands strong health care measures and campaigns to control the disaster.
    Keywords corona vaccine ; pandemic ; non-pharmaceutical interventions ; karachi ; Medicine ; R
    Subject code 302
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Advance Educational Institute & Research Centre
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: TOTAL PHENOLIC CONTENT AND IN-VITRO ANTIOXIDANT PROPERTY OF THE STEM EXTRACTS OF CALLICARPA MACROPHYLA

    Singh Arjun / Sarathe Ashish Kumar / Tiwari Rajeev Lochan / Sharma Raju / Khan Shaheen Parveen

    International Research Journal of Pharmacy, Vol 3, Iss 5, Pp 452-

    2012  Volume 456

    Abstract: Several plants traditionally used in treatment of a variety of infections in Southern Asia are reported in ethnobotanical surveys. Many of these plants including callicarpa macrophyla lack scientific reports to support their medicinal importance. The ... ...

    Abstract Several plants traditionally used in treatment of a variety of infections in Southern Asia are reported in ethnobotanical surveys. Many of these plants including callicarpa macrophyla lack scientific reports to support their medicinal importance. The antioxidant activities and phenolic contents of the acetone, ethanol and aqueous extracts of the stems of Callicarpa macrophyla were evaluated using in vitro standard methods. The total phenol, total flavonoids and proanthocyanidin content were determined spectrophotometrically. Quercetin, Tannic acid and catechin equivalents were used for these parameters. The antioxidant activities of the stem extracts of this plant were determined by ABTS, DPPH, and ferrous reducing antioxidant property (FRAP) methods. The quantity of the phenolic compounds, flavonoids and proanthocyanidins detected differ significantly in the various extracts. The phenolics were significantly higher than the flavonoids and proanthocyanidin contents in all the extracts investigated. The ferric reducing ability and the radical scavenging activities of the extracts were very high and dose-dependent. The ethanol extract had the highest antioxidant activity, followed by the acetone extract while the aqueous extract was the least active. Reacting with ABTS, the 50% inhibitory concentrations (IC50) were (0.0429 ± 0.04 mg/ml) for aqueous, (0.0317 ± 0.04 mg/ml) for acetone and (0.0306 ± 0.04 mg/ml) for ethanol extracts while they inhibited DPPH radical with 50% inhibitory concentration (IC50) values of 0.0646 ± 0.02 mg/ml (aqueous), 0.0482 ± 0.02 mg/ml (acetone) and 0.0422 ± 0.03 mg/ml (ethanol). A correlation between the antioxidant activity and the total phenolic contents of the extracts indicated that phenolic compounds were the dominant contributors to the antioxidant activity of the plant. This study, therefore, demonstrated that Calicarpa macrophyla has strong antioxidant property and free radical scavenging capability.
    Keywords DPPH radical ; free radical scavenging ; ABTS ; ferrous reducing ; flavonoids. ; Pharmacy and materia medica ; RS1-441 ; Medicine ; R ; DOAJ:Pharmacy and materia medica ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 540
    Language English
    Publishing date 2012-05-01T00:00:00Z
    Publisher International Research Journal of Pharmacy
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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