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  1. Article ; Online: Enhancement of combustion effect leading to improved performance and exhaust emissions of an SI engine with ferrous oxide and graphite nanoparticles.

    Siddiqui, Yasir Hussain / Shakaib, Muhammad / Rasheed, Adnan / Ali, Hafiz Muhammad / Azeem, Syed Mohammad Rizwan / Siddique, Athar Husain / Shafiq, Muhammad

    Environmental science and pollution research international

    2023  

    Abstract: The present study was conducted to investigate the effectiveness of new, less toxic, less harmful, and nonmetallic graphite (G) and metallic iron oxide ( ... ...

    Abstract The present study was conducted to investigate the effectiveness of new, less toxic, less harmful, and nonmetallic graphite (G) and metallic iron oxide (Fe
    Language English
    Publishing date 2023-08-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-28556-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  2. Article ; Online: A comprehensive review on clinical and mechanistic pathophysiological aspects of COVID-19 Malady: How far have we come?

    Shakaib, Baila / Zohra, Tanzeel / Ikram, Aamer / Shakaib, Muhammad Bin / Ali, Amna / Bashir, Adnan / Salman, Muhammad / Khan, Mumtaz Ali / Ansari, Jamil

    Virology journal

    2021  Volume 18, Issue 1, Page(s) 120

    Abstract: Since its outbreak in 2019, the coronavirus disease (COVID-19) has become a pandemic, affecting more than 52 million people and causing more than 1 million mortalities globally till date. Current research reveals a wide array of disease manifestations ... ...

    Abstract Since its outbreak in 2019, the coronavirus disease (COVID-19) has become a pandemic, affecting more than 52 million people and causing more than 1 million mortalities globally till date. Current research reveals a wide array of disease manifestations and behaviors encompassing multiple organ systems in body and immense systemic inflammation, which have been summarized in this review. Data from a number of scientific reviews, research articles, case series, observational studies, and case reports were retrieved by utilizing online search engines such as Cochrane, PubMed, and Scopus from December 2019 to November 2020. The data for prevalence of signs and symptoms, underlying disease mechanisms and comorbidities were analyzed using SPSS version 25. This review will discuss a wide range of COVID-19 clinical presentations recorded till date, and the current understanding of both the underlying general as well as system specific pathophysiologic, and pathogenetic pathways. These include direct viral penetration into host cells through ACE2 receptors, induction of inflammosomes and immune response through viral proteins, and the initiation of system-wide inflammation and cytokine production. Moreover, peripheral organ damage and underlying comorbid diseases which can lead to short term and long term, reversible and irreversible damage to the body have also been studied. We concluded that underlying comorbidities and their pathological effects on the body contributed immensely and determine the resultant disease severity and mortality of the patients. Presently there is no drug approved for treatment of COVID-19, however multiple vaccines are now in use and research for more is underway.
    MeSH term(s) Antiviral Agents/therapeutic use ; COVID-19/epidemiology ; COVID-19/pathology ; Comorbidity ; Humans ; Pandemics/prevention & control ; Risk Factors ; Severity of Illness Index ; COVID-19 Drug Treatment
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-06-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2160640-7
    ISSN 1743-422X ; 1743-422X
    ISSN (online) 1743-422X
    ISSN 1743-422X
    DOI 10.1186/s12985-021-01578-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A comprehensive review on clinical and mechanistic pathophysiological aspects of COVID-19 Malady: How far have we come?

    Shakaib, Baila / Zohra, Tanzeel / Ikram, Aamer / Shakaib, Muhammad Bin / Ali, Amna / Bashir, Adnan / Salman, Muhammad / khan, Mumtaz Ali / Ansari, Jamil

    Virology journal. 2021 Dec., v. 18, no. 1

    2021  

    Abstract: Since its outbreak in 2019, the coronavirus disease (COVID-19) has become a pandemic, affecting more than 52 million people and causing more than 1 million mortalities globally till date. Current research reveals a wide array of disease manifestations ... ...

    Abstract Since its outbreak in 2019, the coronavirus disease (COVID-19) has become a pandemic, affecting more than 52 million people and causing more than 1 million mortalities globally till date. Current research reveals a wide array of disease manifestations and behaviors encompassing multiple organ systems in body and immense systemic inflammation, which have been summarized in this review. Data from a number of scientific reviews, research articles, case series, observational studies, and case reports were retrieved by utilizing online search engines such as Cochrane, PubMed, and Scopus from December 2019 to November 2020. The data for prevalence of signs and symptoms, underlying disease mechanisms and comorbidities were analyzed using SPSS version 25. This review will discuss a wide range of COVID-19 clinical presentations recorded till date, and the current understanding of both the underlying general as well as system specific pathophysiologic, and pathogenetic pathways. These include direct viral penetration into host cells through ACE2 receptors, induction of inflammosomes and immune response through viral proteins, and the initiation of system-wide inflammation and cytokine production. Moreover, peripheral organ damage and underlying comorbid diseases which can lead to short term and long term, reversible and irreversible damage to the body have also been studied. We concluded that underlying comorbidities and their pathological effects on the body contributed immensely and determine the resultant disease severity and mortality of the patients. Presently there is no drug approved for treatment of COVID-19, however multiple vaccines are now in use and research for more is underway.
    Keywords COVID-19 infection ; cytokines ; disease severity ; immune response ; inflammation ; mortality ; pandemic ; pathophysiology ; virology
    Language English
    Dates of publication 2021-12
    Size p. 120.
    Publishing place BioMed Central
    Document type Article
    Note Review
    ISSN 1743-422X
    DOI 10.1186/s12985-021-01578-0
    Database NAL-Catalogue (AGRICOLA)

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