LIVIVO - Search results -

Search results

Result 1 - 10 of total 226

Search options

Article ; Online: Mathematical foundations of an ultra coarse-grained slip link model.

Shanbhag, Sachin

2019 Volume 151, Issue 4, Page(s) 44903

Abstract: The master equation underlying ecoSLM, an ultra-coarse-grained slip link model, is presented. In the absence of constraint release, the equilibrium and dynamic properties of the discrete master equation for large chains are found to be virtually ... ...

Abstract	The master equation underlying ecoSLM, an ultra-coarse-grained slip link model, is presented. In the absence of constraint release, the equilibrium and dynamic properties of the discrete master equation for large chains are found to be virtually identical to the continuous Fokker-Planck equation for Brownian particles diffusing in a potential. A single-chain microscopic model with repulsion between adjacent slip links is described. It is approximately consistent with the quadratic fluctuation potential used in ecoSLM. Mapping ecoSLM with fine-grained slip link models or experiments requires specification of an effective friction as a function of molecular weight. Methods to accomplish this are discussed. Collectively, the mathematical framework described provides an interface for fine-grained slip link models to potentially use ecoSLM for extreme coarse-graining.
Language	English
Publishing date	2019-07-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	3113-6
ISSN	1089-7690 ; 0021-9606
ISSN (online)	1089-7690
ISSN	0021-9606
DOI	10.1063/1.5111032
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 49/16: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Intracellular recordings reveal integrative function of the basolateral amygdala in acoustic communication.

Voytenko, Sergiy / Shanbhag, Sharad / Wenstrup, Jeffrey / Galazyuk, Alexander

Journal of neurophysiology

2023 Volume 129, Issue 6, Page(s) 1334–1343

Abstract: The amygdala, a brain center of emotional expression, contributes to appropriate behavior responses during acoustic communication. In support of that role, the basolateral amygdala (BLA) analyzes the meaning of vocalizations through the integration of ... ...

Abstract	The amygdala, a brain center of emotional expression, contributes to appropriate behavior responses during acoustic communication. In support of that role, the basolateral amygdala (BLA) analyzes the meaning of vocalizations through the integration of multiple acoustic inputs with information from other senses and an animal's internal state. The mechanisms underlying this integration are poorly understood. This study focuses on the integration of vocalization-related inputs to the BLA from auditory centers during this processing. We used intracellular recordings of BLA neurons in unanesthetized big brown bats that rely heavily on a complex vocal repertoire during social interactions. Postsynaptic and spiking responses of BLA neurons were recorded to three vocal sequences that are closely related to distinct behaviors (appeasement, low-level aggression, and high-level aggression) and have different emotional valence. Our novel findings are that most BLA neurons showed postsynaptic responses to one or more vocalizations (31 of 46) but that many fewer neurons showed spiking responses (8 of 46). The spiking responses were more selective than postsynaptic potential (PSP) responses. Furthermore, vocal stimuli associated with either positive or negative valence were similarly effective in eliciting excitatory postsynaptic potentials (EPSPs), inhibitory postsynaptic potentials (IPSPs), and spiking responses. This indicates that BLA neurons process both positive- and negative-valence vocal stimuli. The greater selectivity of spiking responses than PSP responses suggests an integrative role for processing within the BLA to enhance response specificity in acoustic communication.
MeSH term(s)	Animals ; Basolateral Nuclear Complex ; Neurons/physiology ; Amygdala/physiology ; Vocalization, Animal/physiology ; Acoustics
Language	English
Publishing date	2023-04-26
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	80161-6
ISSN	1522-1598 ; 0022-3077
ISSN (online)	1522-1598
ISSN	0022-3077
DOI	10.1152/jn.00103.2023
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uc I Zs.224: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Efficient, Breathable, and Compostable Multilayer Air Filter Material Prepared from Plant-Derived Biopolymers.

Wu, Rong / Shanbhag, Sneha / Selvaganapathy, P Ravi

Membranes

2023 Volume 13, Issue 4

Abstract: State-of-art face masks and respirators are fabricated as single-use devices using microfibrous polypropylene fabrics, which are challenging to be collected and recycled at a community scale. Compostable face masks and respirators can offer a viable ... ...

Abstract	State-of-art face masks and respirators are fabricated as single-use devices using microfibrous polypropylene fabrics, which are challenging to be collected and recycled at a community scale. Compostable face masks and respirators can offer a viable alternative to reducing their environmental impact. In this work, we have developed a compostable air filter produced by electrospinning a plant-derived protein, zein, on a craft paper-based substrate. The electrospun material is tailored to be humidity tolerant and mechanically durable by crosslinking zein with citric acid. The electrospun material demonstrated a high particle filtration efficiency (PFE) of 91.15% and a high pressure drop (PD) of 191.2 Pa using an aerosol particle diameter of 75 ± 2 nm at a face velocity of 10 cm/s. We deployed a pleated structure to reduce the PD or improve the breathability of the electrospun material without compromising the PFE over short- and long-duration tests. Over a 1 h salt loading test, the PD of a single-layer pleated filter increased from 28.9 to 39.1 Pa, while that of the flat sample increased from 169.3 to 327 Pa. The stacking of pleated layers enhanced the PFE while retaining a low PD; a two-layer stack with a pleat width of 5 mm offers a PFE of 95.4 ± 0.34% and a low PD of 75.2 ± 6.1 Pa.
Language	English
Publishing date	2023-03-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2614641-1
ISSN	2077-0375
ISSN	2077-0375
DOI	10.3390/membranes13040380
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Large amplitude oscillatory shear study of a colloidal gel near the critical state.

Suman, Khushboo / Shanbhag, Sachin / Joshi, Yogesh M

The Journal of chemical physics

2023 Volume 158, Issue 5, Page(s) 54907

Abstract: A system undergoing sol-gel transition passes through a unique point, known as the critical gel state, where it forms the weakest space spanning percolated network. We investigate the nonlinear viscoelastic behavior of a colloidal dispersion at the ... ...

Abstract	A system undergoing sol-gel transition passes through a unique point, known as the critical gel state, where it forms the weakest space spanning percolated network. We investigate the nonlinear viscoelastic behavior of a colloidal dispersion at the critical gel state using large amplitude oscillatory shear rheology. The colloidal gel at the critical point is subjected to oscillatory shear flow with increasing strain amplitude at different frequencies. We observe that the first harmonic of the elastic and viscous moduli exhibits a monotonic decrease as the material undergoes a linear to nonlinear transition. We analyze the stress waveform across this transition and obtain the nonlinear moduli and viscosity as a function of frequency and strain amplitude. The analysis of the nonlinear moduli and viscosities suggests intracycle strain stiffening and intracycle shear thinning in the colloidal dispersion. Based on the insights obtained from the nonlinear analysis, we propose a potential scenario of the microstructural changes occurring in the nonlinear region. We also develop an integral model using the time-strain separable Kaye-Bernstein-Kearsley-Zapas constitutive equation with a power-law relaxation modulus and damping function obtained from experiments. The proposed model with a slight adjustment of the damping function inferred using a spectral method, compares well with experimental data at all frequencies.
Language	English
Publishing date	2023-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	3113-6
ISSN	1089-7690 ; 0021-9606
ISSN (online)	1089-7690
ISSN	0021-9606
DOI	10.1063/5.0129416
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 49/16: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Fast Slip Link Model for Bidisperse Linear Polymer Melts

Shanbhag, Sachin

Macromolecules. 2019 Apr. 11, v. 52, no. 8

2019

Abstract: A simple and fast slip link model called ecoSLM is presented and applied to mixtures of short and long linear polymers. It explicitly models binary entanglements between chains as slip links and offers a natural and powerful representation of constraint ... ...

Abstract	A simple and fast slip link model called ecoSLM is presented and applied to mixtures of short and long linear polymers. It explicitly models binary entanglements between chains as slip links and offers a natural and powerful representation of constraint release. A multichain Markov chain Monte Carlo algorithm is developed to simulate stress relaxation following a step shear in the linear viscoelastic regime. The time required for accumulated slack to equilibrate along the chain contour is subsumed into the definition of the time step. The parameters of the ecoSLM are determined from data on monodisperse linears by mapping the time and modulus scales and specifying a parameter γ that is related to the variation of the zero-shear viscosity with molar mass. Predictions of viscosity and dynamic moduli obtained using the ecoSLM are in remarkably good agreement with experimental data on 1,4-polybutadienes. Thus, ecoSLM fills a valuable niche in describing the long and intermediate timescale dynamics of bidisperse blends in which constraint release is determined by a complex interplay of mechanisms at a computational cost that is a few orders of magnitude smaller than other, more sophisticated, slip link models.
Keywords	Markov chain ; algorithms ; melting ; models ; molecular weight ; polymers ; prediction ; stress relaxation ; viscoelasticity ; viscosity
Language	English
Dates of publication	2019-0411
Size	p. 3092-3103.
Publishing place	American Chemical Society
Document type	Article
ZDB-ID	1491942-4
ISSN	1520-5835 ; 0024-9297
ISSN (online)	1520-5835
ISSN	0024-9297
DOI	10.1021/acs.macromol.8b02367
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article: The Mouse Inferior Colliculus Responds Preferentially to Non-Ultrasonic Vocalizations.

Tehrani, Mahtab / Shanbhag, Sharad / Huyck, Julia J / Patel, Rahi / Kazimiersky, Diana / Wenstrup, Jeffrey J

bioRxiv : the preprint server for biology

2024

Abstract: The inferior colliculus (IC), the midbrain auditory integration center, analyzes information about social vocalizations and provides substrates for higher level processing of vocal signals. We used multi-channel recordings to characterize and localize ... ...

Abstract	The inferior colliculus (IC), the midbrain auditory integration center, analyzes information about social vocalizations and provides substrates for higher level processing of vocal signals. We used multi-channel recordings to characterize and localize responses to social vocalizations and synthetic stimuli within the IC of female and male mice, both urethane-anesthetized and unanesthetized. We compared responses to ultrasonic vocalizations (USVs) with other vocalizations in the mouse repertoire and related vocal responses to frequency tuning, IC subdivisions, and sex. Responses to lower frequency, broadband social vocalizations were widespread in IC, well represented throughout the tonotopic axis, across subdivisions, and in both sexes. Responses to USVs were much more limited. Although we observed some differences in tonal and vocal responses by sex and subdivision, representations of vocal responses by sex and subdivision were largely the same. For most units, responses to vocal signals occurred only when frequency response areas overlapped with spectra of the vocal signals. Since tuning to frequencies contained within the highest frequency USVs is limited (< 15% of IC units), responses to these vocalizations are correspondingly limited (< 5% of sound-responsive units). These results highlight a paradox of USV processing in some rodents: although USVs are the most abundant social vocalization, their representation and the representation of corresponding frequencies is less than lower frequency social vocalizations. We interpret this paradox in light of observations suggesting that USVs with lower frequency elements (<50 kHz) are associated with increased emotional intensity and engage a larger population of neurons in the mouse auditory system. Significance statement: The inferior colliculus (IC) integrates multiple inputs to analyze information about social vocalizations. In mice, we show that the most common type of social vocalization, the ultrasonic vocalization or USV, was poorly represented in IC compared to lower frequency vocalizations. For most neurons, responses to vocal signals occurred only when frequency response areas overlapped with vocalization spectra. These results highlight a paradox of USV processing in some rodent auditory systems: although USVs are the most abundant social vocalization, their representation and representation of corresponding frequencies is less than lower frequency social vocalizations. These results suggest that USVs with lower frequency elements (<50 kHz)-associated with increased emotional intensity-will engage a larger population of neurons in the mouse auditory system.
Language	English
Publishing date	2024-02-11
Publishing country	United States
Document type	Preprint
DOI	10.1101/2024.02.09.579664
Database	MEDical Literature Analysis and Retrieval System OnLINE

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: The Mouse Inferior Colliculus Responds Preferentially to Non-Ultrasonic Vocalizations.

Tehrani, Mahtab / Shanbhag, Sharad / Huyck, Julia J / Patel, Rahi / Kazimierski, Diana / Wenstrup, Jeffrey J

eNeuro

2024 Volume 11, Issue 4

Abstract: The inferior colliculus (IC), the midbrain auditory integration center, analyzes information about social vocalizations and provides substrates for higher level processing of vocal signals. We used multichannel recordings to characterize and localize ... ...

Abstract	The inferior colliculus (IC), the midbrain auditory integration center, analyzes information about social vocalizations and provides substrates for higher level processing of vocal signals. We used multichannel recordings to characterize and localize responses to social vocalizations and synthetic stimuli within the IC of female and male mice, both urethane anesthetized and unanesthetized. We compared responses to ultrasonic vocalizations (USVs) with other vocalizations in the mouse repertoire and related vocal responses to frequency tuning, IC subdivisions, and sex. Responses to lower frequency, broadband social vocalizations were widespread in IC, well represented throughout the tonotopic axis, across subdivisions, and in both sexes. Responses to USVs were much more limited. Although we observed some differences in tonal and vocal responses by sex and subdivision, representations of vocal responses by sex and subdivision were largely the same. For most units, responses to vocal signals occurred only when frequency response areas overlapped with spectra of the vocal signals. Since tuning to frequencies contained within the highest frequency USVs is limited (<15% of IC units), responses to these vocalizations are correspondingly limited (<5% of sound-responsive units). These results highlight a paradox of USV processing in some rodents: although USVs are the most abundant social vocalization, their representation and the representation of corresponding frequencies are less than lower frequency social vocalizations. We interpret this paradox in light of observations suggesting that USVs with lower frequency elements (<50 kHz) are associated with increased emotional intensity and engage a larger population of neurons in the mouse auditory system.
MeSH term(s)	Mice ; Female ; Male ; Animals ; Inferior Colliculi/physiology ; Ultrasonics ; Vocalization, Animal/physiology ; Sound ; Mesencephalon
Language	English
Publishing date	2024-04-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2800598-3
ISSN	2373-2822 ; 2373-2822
ISSN (online)	2373-2822
ISSN	2373-2822
DOI	10.1523/ENEURO.0097-24.2024
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Antibody profile in post-vaccinated & SARS-CoV-2 infected individuals.

Patil, Rucha / Shanbhag, Sharda / Shankarkumar, Aruna / Madkaikar, Manisha

The Indian journal of medical research

2022 Volume 155, Issue 5&6, Page(s) 538–545

Abstract: Background & objectives: During the COVID-19 pandemic it was important to assess the antibody profile in individuals vaccinated with Covaxin (BBV152) and Covishield (ChAdOx1 nCoV-19) with both 28 and 84 days gaps between two doses, those infected with ... ...

Abstract	Background & objectives: During the COVID-19 pandemic it was important to assess the antibody profile in individuals vaccinated with Covaxin (BBV152) and Covishield (ChAdOx1 nCoV-19) with both 28 and 84 days gaps between two doses, those infected with SARS-CoV-2 and post-COVID-19-infected individuals vaccinated with only one dose of either of the vaccines. The present study was aimed to assess these objectives. Methods: Fifty real time reverse transcription-polymerase chain reaction (qRT-PCR)-confirmed COVID-19-infected individuals, along with 90 COVID-19-naïve (BBV152 and ChAdOx1 nCov-19)-vaccinated individuals, were included in the study. Individuals who received a single dose of either vaccine with a confirmed past diagnosis of SARS-CoV-2 infection (n=15) were also included. Blood samples were collected strictly between the 4 Results: There was an overall 97.7 per cent seropositivity rate in vaccinated individuals, and a strong correlation (R Interpretation & conclusions: High neutralizing and spike-specific antibodies were developed in individuals vaccinated only with one dose of either vaccine post-SARS-CoV-2 infection. With the main priority being vaccinating majority of the population in our country, single-dose administration to such individuals would be a sensible way to make the most of the limited supplies. Furthermore, neutralizing antibody levels observed in COVID-19-naïve vaccinees imply the need for booster vaccination.
MeSH term(s)	Humans ; SARS-CoV-2 ; COVID-19 ; ChAdOx1 nCoV-19 ; Pandemics ; Viral Vaccines ; COVID-19 Vaccines ; Antibodies, Neutralizing ; Antibodies, Viral ; Vaccination
Chemical Substances	ChAdOx1 nCoV-19 (B5S3K2V0G8) ; Viral Vaccines ; COVID-19 Vaccines ; Antibodies, Neutralizing ; Antibodies, Viral
Language	English
Publishing date	2022-09-20
Publishing country	India
Document type	Journal Article
ZDB-ID	390883-5
ISSN	0971-5916 ; 0019-5340
ISSN	0971-5916 ; 0019-5340
DOI	10.4103/ijmr.ijmr_3330_21
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.143: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Online: The Method of Harmonic Balance for the Giesekus Model under Oscillatory Shear

Mittal, Shivangi / Joshi, Yogesh M. / Shanbhag, Sachin

2023

Abstract: The method of harmonic balance (HB) is a spectrally accurate method used to obtain periodic steady state solutions to dynamical systems subjected to periodic perturbations. We adapt HB to solve for the stress response of the Giesekus model under large ... ...

Abstract	The method of harmonic balance (HB) is a spectrally accurate method used to obtain periodic steady state solutions to dynamical systems subjected to periodic perturbations. We adapt HB to solve for the stress response of the Giesekus model under large amplitude oscillatory shear (LAOS) deformation. HB transforms the system of differential equations to a set of nonlinear algebraic equations in the Fourier coefficients. Convergence studies find that the difference between the HB and true solutions decays exponentially with the number of harmonics ($H$) included in the ansatz as $e^{-m H}$. The decay coefficient $m$ decreases with increasing strain amplitude, and exhibits a "U" shaped dependence on applied frequency. The computational cost of HB increases slightly faster than linearly with $H$. The net result of rapid convergence and modest increase in computational cost with increasing $H$ implies that HB outperforms the conventional method of using numerical integration to solve differential constitutive equations under oscillatory shear. Numerical experiments find that HB is simultaneously about three orders of magnitude cheaper, and several orders of magnitude more accurate than numerical integration. Thus, it offers a compelling value proposition for parameter estimation or model selection. Comment: submitted to JNNFM
Keywords	Mathematics - Numerical Analysis ; Condensed Matter - Materials Science
Subject code	518
Publishing date	2023-01-26
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Unusual dynamics of ring probes in linear matrices

Shanbhag, Sachin

Journal of polymer science. 2017 Jan. 15, v. 55, no. 2

2017

Abstract: We perform Monte Carlo simulations of ring and linear polymers in linear matrices, and investigate the diffusivity of the probes. As the matrix chain length Nâ is increased from 10 to 300 monomers, the diffusivity Dâ of a linear probe (Nââ=â300) ...

Abstract	We perform Monte Carlo simulations of ring and linear polymers in linear matrices, and investigate the diffusivity of the probes. As the matrix chain length Nâ is increased from 10 to 300 monomers, the diffusivity Dâ of a linear probe (Nââ=â300) decreases monotonically, while that of a ring probe Dáµ£ varies nonâmonotonically, with a peak around Nmâ30â75. We perform additional simulations with a single probe molecule (Nr=Nl=150) in a linear matrix (Nm=10â150). The nonâmonotonicity in Dáµ£ persists even after ringâring interactions are eliminated. Topology dependent differences in the shortâtime dynamics of the probes are observed; unlike linear probes, meanâsquared displacements of ring probes depend on Nâ. Primitive path analysis suggests that the difference in dynamics originates from differences in entanglement structure. For linear probes, the degree of entanglement is independent of Nâ. For ring probes, we observe two regimes: when Nâ is small, the number of threadings decreases as Nâ increases, eventually transitioning to a plateau. In the small Nâ regime, the change in the degree of entanglement offsets the change in the mobility of the matrix chains, leading to a nonâmonotonic variation in Dáµ£. Â© 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2017, 55, 169â177
Keywords	Monte Carlo method ; diffusivity ; path analysis ; polymers ; topology
Language	English
Dates of publication	2017-0115
Size	p. 169-177.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	1473448-5
ISSN	1099-0488 ; 0887-6266
ISSN (online)	1099-0488
ISSN	0887-6266
DOI	10.1002/polb.24252
Database	NAL-Catalogue (AGRICOLA)

Order via subito

To top

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito