LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 4 of total 4

Search options

  1. Article ; Online: A single-centre retrospective case series of Anakinra for incident calcium pyrophosphate deposition disease.

    Lian, Alwin / Shandilya, Apoorva / Riordan, John

    Clinical rheumatology

    2023  Volume 42, Issue 7, Page(s) 1833–1837

    Abstract: In this 2-year retrospective case series, we characterise the calcium pyrophosphate deposition disease (CPPD) inpatient cohort at a single centre and assess the efficacy and safety of anakinra in its treatment. Adult inpatients with CPPD between 1st ... ...

    Abstract In this 2-year retrospective case series, we characterise the calcium pyrophosphate deposition disease (CPPD) inpatient cohort at a single centre and assess the efficacy and safety of anakinra in its treatment. Adult inpatients with CPPD between 1st September 2020 and 30th September 2022 were identified by ICD-10 codes and confirmed based on clinical diagnosis and either CPP crystals on aspirate or chondrocalcinosis on imaging. Charts were reviewed for demographic, clinical, biochemical data, treatment choice, and response. Response to treatment was determined from chart documentation and calculated from time of first CPPD treatment. Daily responses to anakinra were recorded if anakinra was used. Seventy patients accounting for 79 cases of CPPD were identified. Twelve cases received anakinra, whilst 67 cases received conventional therapy only. Patient receiving anakinra were predominantly male, had multiple comorbidities, and had higher CRPs and serum creatinine when compared to the non-anakinra group. Anakinra was rapidly effective with the mean time to substantial and complete response being 1.7 and 3.6 days respectively. Anakinra was well tolerated. This study adds to the small amount of retrospective data present about the use of anakinra in CPPD. We observed a rapid response to anakinra in our cohort with minimal adverse drug reactions. Key Points • Treatment of CPPD with anakinra appears to be rapidly efficacious without safety concerns.
    MeSH term(s) Adult ; Humans ; Male ; Female ; Chondrocalcinosis/drug therapy ; Chondrocalcinosis/diagnosis ; Interleukin 1 Receptor Antagonist Protein/adverse effects ; Retrospective Studies ; Comorbidity ; Calcium Pyrophosphate
    Chemical Substances Interleukin 1 Receptor Antagonist Protein ; Calcium Pyrophosphate (X69NU20D19)
    Language English
    Publishing date 2023-03-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 604755-5
    ISSN 1434-9949 ; 0770-3198
    ISSN (online) 1434-9949
    ISSN 0770-3198
    DOI 10.1007/s10067-023-06573-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1740: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Leg impairment affects the reproductive attributes of a ladybird, Menochilus sexmaculatus (Fabricius)

    Shandilya, Apoorva / Geetanjali Mishra / Omkar

    Korean Society of Applied Entomology Journal of Asia-Pacific entomology. 2018 Sept., v. 21, no. 3

    2018  

    Abstract: Natural injuries and their causes have recently garnered attention amongst researchers, however the effects of these injuries on life history traits are still sparsely investigated. In the few studies that have been conducted injuries are known to have a ...

    Abstract Natural injuries and their causes have recently garnered attention amongst researchers, however the effects of these injuries on life history traits are still sparsely investigated. In the few studies that have been conducted injuries are known to have a debilitating effect on male virility and reproductive performance. Thus the effect of leg injuries in males on mating behaviour and reproductive output in the ladybird beetle, Menochilus sexmaculatus was investigated. This is the first study on the effect of injury on any life history trait in Coccinellidae. The legs of the male were amputated at three different joints on the same side and opposite sides for one leg or two legs. These amputated males were paired with uninjured females and the mating behaviour and subsequent reproductive output was observed. Time to commence mating, latent period and mating duration in impaired males were observed and were all found to be higher than that of uninjured males. Fecundity and percent egg viability were reduced in all impaired male pairs. Males with physical disability were found to copulate for an extended duration, perhaps to ensure maximum paternity.
    Keywords Coccinellidae ; eggs ; fecundity ; females ; latent period ; legs ; life history ; males ; mating behavior ; paternity ; reproductive performance ; researchers ; viability
    Language English
    Dates of publication 2018-09
    Size p. 797-806.
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 1226-8615
    DOI 10.1016/j.aspen.2018.05.007
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: A roadmap for ladybird conservation and recovery

    Soares, António O. / Haelewaters, Danny / Ameixa, Olga M. C. C. / Borges, Isabel / Brown, Peter M. J. / Cardoso, Pedro / de Groot, Michiel D. / Evans, Edward W. / Grez, Audrey A. / Hochkirch, Axel / Holecová, Milada / Honek, Alois / Kulfan, Ján / Lillebø, Ana I. / Martinková, Zdenka / Michaud, J. P. / Nedvěd, Oldřich / Omkar / Roy, Helen E. /
    Saxena, Swati / Shandilya, Apoorva / Sentis, Arnaud / Skuhrovec, Jiri / Viglášová, Sandra / Zach, Peter / Zaviezo, Tania / Losey, John E.

    Conservation Biology. 2023 Feb., v. 37, no. 1 p.e13965-

    2023  

    Abstract: Ladybirds (Coleoptera: Coccinellidae) provide services that are critical to food production, and they fulfill an ecological role as a food source for predators. The richness, abundance, and distribution of ladybirds, however, are compromised by many ... ...

    Abstract Ladybirds (Coleoptera: Coccinellidae) provide services that are critical to food production, and they fulfill an ecological role as a food source for predators. The richness, abundance, and distribution of ladybirds, however, are compromised by many anthropogenic threats. Meanwhile, a lack of knowledge of the conservation status of most species and the factors driving their population dynamics hinders the development and implementation of conservation strategies for ladybirds. We conducted a review of the literature on the ecology, diversity, and conservation of ladybirds to identify their key ecological threats. Ladybird populations are most affected by climate factors, landscape composition, and biological invasions. We suggest mitigating actions for ladybird conservation and recovery. Short‐term actions include citizen science programs and education, protective measures for habitat recovery and threatened species, prevention of the introduction of non‐native species, and the maintenance and restoration of natural areas and landscape heterogeneity. Mid‐term actions involve the analysis of data from monitoring programs and insect collections to disentangle the effect of different threats to ladybird populations, understand habitat use by taxa on which there is limited knowledge, and quantify temporal trends of abundance, diversity, and biomass along a management‐intensity gradient. Long‐term actions include the development of a worldwide monitoring program based on standardized sampling to fill data gaps, increase explanatory power, streamline analyses, and facilitate global collaborations.
    Keywords Coccinellidae ; biomass ; citizen science ; climate ; conservation status ; education ; food production ; habitat preferences ; habitats ; insects ; introduced species ; landscapes ; population dynamics ; threatened species
    Language English
    Dates of publication 2023-02
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note REVIEW
    ZDB-ID 58735-7
    ISSN 1523-1739 ; 0888-8892
    ISSN (online) 1523-1739
    ISSN 0888-8892
    DOI 10.1111/cobi.13965
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4919: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: A roadmap for ladybird conservation and recovery.

    Soares, António O / Haelewaters, Danny / Ameixa, Olga M C C / Borges, Isabel / Brown, Peter M J / Cardoso, Pedro / de Groot, Michiel D / Evans, Edward W / Grez, Audrey A / Hochkirch, Axel / Holecová, Milada / Honěk, Alois / Kulfan, Ján / Lillebø, Ana I / Martinková, Zdenka / Michaud, J P / Nedvěd, Oldřich / Omkar / Roy, Helen E /
    Saxena, Swati / Shandilya, Apoorva / Sentis, Arnaud / Skuhrovec, Jiri / Viglášová, Sandra / Zach, Peter / Zaviezo, Tania / Losey, John E

    Conservation biology : the journal of the Society for Conservation Biology

    2022  Volume 37, Issue 1, Page(s) e13965

    Abstract: Ladybirds (Coleoptera: Coccinellidae) provide services that are critical to food production, and they fulfill an ecological role as a food source for predators. The richness, abundance, and distribution of ladybirds, however, are compromised by many ... ...

    Abstract Ladybirds (Coleoptera: Coccinellidae) provide services that are critical to food production, and they fulfill an ecological role as a food source for predators. The richness, abundance, and distribution of ladybirds, however, are compromised by many anthropogenic threats. Meanwhile, a lack of knowledge of the conservation status of most species and the factors driving their population dynamics hinders the development and implementation of conservation strategies for ladybirds. We conducted a review of the literature on the ecology, diversity, and conservation of ladybirds to identify their key ecological threats. Ladybird populations are most affected by climate factors, landscape composition, and biological invasions. We suggest mitigating actions for ladybird conservation and recovery. Short-term actions include citizen science programs and education, protective measures for habitat recovery and threatened species, prevention of the introduction of non-native species, and the maintenance and restoration of natural areas and landscape heterogeneity. Mid-term actions involve the analysis of data from monitoring programs and insect collections to disentangle the effect of different threats to ladybird populations, understand habitat use by taxa on which there is limited knowledge, and quantify temporal trends of abundance, diversity, and biomass along a management-intensity gradient. Long-term actions include the development of a worldwide monitoring program based on standardized sampling to fill data gaps, increase explanatory power, streamline analyses, and facilitate global collaborations.
    MeSH term(s) Animals ; Conservation of Natural Resources ; Ecosystem ; Endangered Species ; Population Dynamics
    Language English
    Publishing date 2022-09-27
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 58735-7
    ISSN 1523-1739 ; 0888-8892
    ISSN (online) 1523-1739
    ISSN 0888-8892
    DOI 10.1111/cobi.13965
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4919: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top