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Article ; Online: Engineering the lymph node environment promotes antigen-specific efficacy in type 1 diabetes and islet transplantation

Joshua M. Gammon / Sean T. Carey / Vikas Saxena / Haleigh B. Eppler / Shannon J. Tsai / Christina Paluskievicz / Yanbao Xiong / Lushen Li / Marian Ackun-Farmmer / Lisa H. Tostanoski / Emily A. Gosselin / Alexis A. Yanes / Xiangbin Zeng / Robert S. Oakes / Jonathan S. Bromberg / Christopher M. Jewell

Nature Communications, Vol 14, Iss 1, Pp 1-

2023  Volume 18

Abstract: Antigen-specific tolerance represents a promising strategy to treat type 1 diabetes and islet allograft rejection. Here, the authors deliver immune signals to lymph nodes to promote antigen-specific regulatory T cells and prevent disease in models of ... ...

Abstract Antigen-specific tolerance represents a promising strategy to treat type 1 diabetes and islet allograft rejection. Here, the authors deliver immune signals to lymph nodes to promote antigen-specific regulatory T cells and prevent disease in models of type 1 diabetes and allogenic islet transplantation.
Keywords Science ; Q
Language English
Publishing date 2023-02-01T00:00:00Z
Publisher Nature Portfolio
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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