Article ; Online: Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K
Proceedings of the National Academy of Sciences of the United States of America
2022 Volume 119, Issue 34, Page(s) e2202926119
Abstract: ... The ... ...
| Abstract | The Ca |
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|---|---|---|---|---|---|---|
| MeSH term(s) | Animals ; Atrial Fibrillation/drug therapy ; Calcium Signaling ; Calmodulin/metabolism ; Cryoelectron Microscopy ; Humans ; Intermediate-Conductance Calcium-Activated Potassium Channels/antagonists & inhibitors ; Intermediate-Conductance Calcium-Activated Potassium Channels/metabolism ; Molecular Docking Simulation ; Mutagenesis, Site-Directed ; Phosphatidylinositol 4,5-Diphosphate ; Potassium Channel Blockers/pharmacology ; Rats | |||||
| Chemical Substances | Calmodulin ; Intermediate-Conductance Calcium-Activated Potassium Channels ; KCNN4 protein, human ; Phosphatidylinositol 4,5-Diphosphate ; Potassium Channel Blockers | |||||
| Language | English | |||||
| Publishing date | 2022-08-15 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 209104-5 | |||||
| ISSN | 1091-6490 ; 0027-8424 | |||||
| ISSN (online) | 1091-6490 | |||||
| ISSN | 0027-8424 | |||||
| DOI | 10.1073/pnas.2202926119 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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