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  1. AU="Sharafeldin, Tamer A"
  2. AU="Alladio, Francesca"
  3. AU="Cheng, Zhiluo"
  4. AU="Silva, Dândara Santos"
  5. AU="Timmann, Dagmar"
  6. AU="Jingping, Lin"
  7. AU="Yoon, Sangwook"
  8. AU="Sedor, John R."
  9. AU="Legrand, Julien"
  10. AU="Mintz, Kevin Todd"
  11. AU="Kösters, Markus"
  12. AU="Castano-Duque, Lina"
  13. AU="Lowry, Gregory V"
  14. AU="Gao, Xiaojuan"
  15. AU="Daniłowicz-Szymanowicz, Ludmiła"
  16. AU="Weber, Jesse N"
  17. AU="Fages-Masmiquel, Ester"
  18. AU="Macias Gil, Raul"
  19. AU="Planchat, Arnaud"
  20. AU="McElrath, Erin E"
  21. AU="Koji Ueda"
  22. AU="Pillas, Diana J"
  23. AU="Thomson, Jason J"
  24. AU="Mitra, Kalyan"
  25. AU="Sanjay Desai"
  26. AU=Cox David J AU=Cox David J
  27. AU="Grebenok, Robert J."
  28. AU="Blackburne, Brittney"
  29. AU="Bortoleti, Bruna Taciane da Silva"
  30. AU="Ehrbar, Martin"
  31. AU="Lepre, Davide"
  32. AU="Olszewska, Zuzanna"
  33. AU="Vojta, Leslie"
  34. AU=Wickstrom Eric AU=Wickstrom Eric
  35. AU="Gangavarapu, Sridevi"
  36. AU="Hussein, Hazem Abdelwaheb"
  37. AU=Cai Yixin AU=Cai Yixin
  38. AU="Hüls, Anke"
  39. AU="Poondru, Srinivasu"
  40. AU="Coca, Daniel"
  41. AU="Lebeau, Paul"
  42. AU="Dehghani, Sedigheh"
  43. AU="Ishibashi, Kenji"
  44. AU="Xu, Yanhua"
  45. AU="Matera, Katarzyna"
  46. AU="Ait-Ouarab, Slimane"
  47. AU="Nicola, Coppede"
  48. AU="Dewitt, John M"
  49. AU="Sorin M. Dudea"
  50. AU="Tanusha D. Ramdin"
  51. AU="Hao, Zehui"
  52. AU="Chauhan, Aman"

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  1. Artikel ; Online: Spillover of Canine Parvovirus Type 2 to Pigs, South Dakota, USA, 2020.

    Temeeyasen, Gun / Sharafeldin, Tamer A / Lin, Chun-Ming / Hause, Ben M

    Emerging infectious diseases

    2022  Band 28, Heft 2, Seite(n) 471–473

    Abstract: In 1978, canine parvovirus type 2 originated from spillover of a feline panleukopenia-like virus, causing a worldwide pandemic of enteritis and myocarditis among canids. In 2020, the virus was identified in pigs in South Dakota, USA, by PCR, sequencing, ... ...

    Abstract In 1978, canine parvovirus type 2 originated from spillover of a feline panleukopenia-like virus, causing a worldwide pandemic of enteritis and myocarditis among canids. In 2020, the virus was identified in pigs in South Dakota, USA, by PCR, sequencing, in situ hybridization, and serology. Genetic analysis suggests spillover from wildlife.
    Mesh-Begriff(e) Animals ; Animals, Wild ; Cats ; Dogs ; Feline Panleukopenia ; Feline Panleukopenia Virus/genetics ; Parvoviridae Infections/epidemiology ; Parvoviridae Infections/veterinary ; Parvovirus, Canine/genetics ; South Dakota/epidemiology ; Swine
    Sprache Englisch
    Erscheinungsdatum 2022-02-20
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2802.211681
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Advances in Poultry Vaccines: Leveraging Biotechnology for Improving Vaccine Development, Stability, and Delivery.

    Abdelaziz, Khaled / Helmy, Yosra A / Yitbarek, Alexander / Hodgins, Douglas C / Sharafeldin, Tamer A / Selim, Mohamed S H

    Vaccines

    2024  Band 12, Heft 2

    Abstract: With the rapidly increasing demand for poultry products and the current challenges facing the poultry industry, the application of biotechnology to enhance poultry production has gained growing significance. Biotechnology encompasses all forms of ... ...

    Abstract With the rapidly increasing demand for poultry products and the current challenges facing the poultry industry, the application of biotechnology to enhance poultry production has gained growing significance. Biotechnology encompasses all forms of technology that can be harnessed to improve poultry health and production efficiency. Notably, biotechnology-based approaches have fueled rapid advances in biological research, including (a) genetic manipulation in poultry breeding to improve the growth and egg production traits and disease resistance, (b) rapid identification of infectious agents using DNA-based approaches, (c) inclusion of natural and synthetic feed additives to poultry diets to enhance their nutritional value and maximize feed utilization by birds, and (d) production of biological products such as vaccines and various types of immunostimulants to increase the defensive activity of the immune system against pathogenic infection. Indeed, managing both existing and newly emerging infectious diseases presents a challenge for poultry production. However, recent strides in vaccine technology are demonstrating significant promise for disease prevention and control. This review focuses on the evolving applications of biotechnology aimed at enhancing vaccine immunogenicity, efficacy, stability, and delivery.
    Sprache Englisch
    Erscheinungsdatum 2024-01-28
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines12020134
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Infection and transmission dynamics of Turkey arthritis reovirus in different age Turkeys

    Kumar, Rahul / Sharafeldin, Tamer A. / Goyal, Sagar M. / Mor, Sunil K. / Porter, Robert E.

    Microbial pathogenesis. 2022 Sept. 14,

    2022  

    Abstract: Turkey arthritis reovirus (TARV) has been established as a cause of lameness in meat type turkeys in the past decade. However, no information is available on the age susceptibility of TARV or its transmission dynamics. We conducted this study to ... ...

    Abstract Turkey arthritis reovirus (TARV) has been established as a cause of lameness in meat type turkeys in the past decade. However, no information is available on the age susceptibility of TARV or its transmission dynamics. We conducted this study to determine the age at which turkey poults are susceptible to TARV infection and whether infected birds can horizontally transmit the virus to their non-infected pen mates (sentinels). Five groups of turkeys were orally inoculated with TARV (∼10⁶ TCID₅₀/ml) at 2, 7, 14, 21 and 28 days of age (DOA). Two days after each challenge, four uninfected sentinel turkeys of equal age were added to the virus-inoculated groups. At one- and two-weeks post infection, turkeys from each group, including two sentinels, were euthanized followed by necropsy. Inoculated birds in all age groups had TARV replication in the intestine and gastrocnemius tendon with no statistically significant variation at p < 0.5. Furthermore, the inoculated birds at different age groups showed consistently high gastrocnemius tendon histologic lesion scores while birds in the 28-days-old age group had numerically lower lesion scores at 14 days post inoculation (dpi). The sentinels, in turn, also showed virus replication in their intestines and tendons and histologic lesions in gastrocnemius tendons. The findings indicate that turkeys at the age of 28 days or less are susceptible to infection with TARV following oral challenge. It was also found that TARV-infected birds could transmit the infection to naïve sentinel turkeys of the same age.
    Schlagwörter Reoviridae ; arthritis ; disease susceptibility ; histology ; intestines ; lameness ; meat ; necropsy ; pathogenesis ; virus replication ; viruses
    Sprache Englisch
    Erscheinungsverlauf 2022-0914
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    Anmerkung Pre-press version
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2022.105790
    Datenquelle NAL Katalog (AGRICOLA)

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  4. Artikel ; Online: Stability of SARS-CoV-2 and other coronaviruses in the environment and on common touch surfaces and the influence of climatic conditions: A review.

    Aboubakr, Hamada A / Sharafeldin, Tamer A / Goyal, Sagar M

    Transboundary and emerging diseases

    2020  Band 68, Heft 2, Seite(n) 296–312

    Abstract: Although the unprecedented efforts the world has been taking to control the spread of the human coronavirus disease (COVID-19) and its causative aetiology [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)], the number of confirmed cases has ... ...

    Abstract Although the unprecedented efforts the world has been taking to control the spread of the human coronavirus disease (COVID-19) and its causative aetiology [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)], the number of confirmed cases has been increasing drastically. Therefore, there is an urgent need for devising more efficient preventive measures, to limit the spread of the infection until an effective treatment or vaccine is available. The preventive measures depend mainly on the understanding of the transmission routes of this virus, its environmental stability, and its persistence on common touch surfaces. Due to the very limited knowledge about SARS-CoV-2, we can speculate its stability in the light of previous studies conducted on other human and animal coronaviruses. In this review, we present the available data on the stability of coronaviruses (CoVs), including SARS-CoV-2, from previous reports to help understand its environmental survival. According to available data, possible airborne transmission of SARS-CoV-2 has been suggested. SARS-CoV-2 and other human and animal CoVs have remarkably short persistence on copper, latex and surfaces with low porosity as compared to other surfaces like stainless steel, plastics, glass and highly porous fabrics. It has also been reported that SARS-CoV-2 is associated with diarrhoea and that it is shed in the faeces of COVID-19 patients. Some CoVs show persistence in human excrement, sewage and waters for a few days. These findings suggest a possible risk of faecal-oral, foodborne and waterborne transmission of SARS-CoV-2 in developing countries that often use sewage-polluted waters in irrigation and have poor water treatment systems. CoVs survive longer in the environment at lower temperatures and lower relative humidity. It has been suggested that large numbers of COVID-19 cases are associated with cold and dry climates in temperate regions of the world and that seasonality of the virus spread is suspected.
    Mesh-Begriff(e) Animals ; COVID-19/prevention & control ; COVID-19/virology ; Climate ; Environment ; Global Health ; Humans ; SARS-CoV-2/pathogenicity ; Seasons ; Touch
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-07-14
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2414822-2
    ISSN 1865-1682 ; 1865-1674
    ISSN (online) 1865-1682
    ISSN 1865-1674
    DOI 10.1111/tbed.13707
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Infection and transmission dynamics of Turkey arthritis reovirus in different age Turkeys.

    Kumar, Rahul / Sharafeldin, Tamer A / Goyal, Sagar M / Mor, Sunil K / Porter, Robert E

    Microbial pathogenesis

    2022  Band 173, Heft Pt A, Seite(n) 105790

    Abstract: Turkey arthritis reovirus (TARV) has been established as a cause of lameness in meat type turkeys in the past decade. However, no information is available on the age susceptibility of TARV or its transmission dynamics. We conducted this study to ... ...

    Abstract Turkey arthritis reovirus (TARV) has been established as a cause of lameness in meat type turkeys in the past decade. However, no information is available on the age susceptibility of TARV or its transmission dynamics. We conducted this study to determine the age at which turkey poults are susceptible to TARV infection and whether infected birds can horizontally transmit the virus to their non-infected pen mates (sentinels). Five groups of turkeys were orally inoculated with TARV (∼10
    Mesh-Begriff(e) Animals ; Turkeys ; Reoviridae ; Reoviridae Infections ; Arthritis ; Antibodies, Viral ; Poultry Diseases
    Chemische Substanzen Antibodies, Viral
    Sprache Englisch
    Erscheinungsdatum 2022-09-25
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2022.105790
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Comparative pathogenesis of turkey reoviruses

    Rahul Kumar / Sharafeldin, Tamer A. / Sobhy, Nader M. / Goyal, Sagar M. / Porter, Robert E. / Mor, Sunil K.

    Avian Pathology. 2022 Sept. 03, v. 51, no. 5 p.435-444

    2022  

    Abstract: Turkey reoviruses have been implicated in multiple disease syndromes resulting in significant economic losses to the turkey industry. It has been known for decades that turkey enteric reovirus (TERV) is involved in poult enteritis complex, but turkey ... ...

    Abstract Turkey reoviruses have been implicated in multiple disease syndromes resulting in significant economic losses to the turkey industry. It has been known for decades that turkey enteric reovirus (TERV) is involved in poult enteritis complex, but turkey arthritis reovirus (TARV), the causative agent of tenosynovitis in turkeys, emerged in 2011. In 2019, we isolated reovirus from several cases of hepatitis in turkeys and tentatively named it turkey hepatitis reovirus (THRV). The comparative pathogenesis of these viruses, and correlation with their genetic make-up (if any), is not known. In this study, we inoculated nine groups of 1-week-old turkey poults with two THRV, five TARV and two TERV via oral route. A tenth group served as a negative control. A subset of birds from each group was euthanised at 3, 5, 7, 14, 21, and 28 days post-inoculation (dpi). Tissues were collected for histology and real-time RT–PCR. All nine viruses were found to be enterotropic; the virus gene copy number in the intestine reached a peak at 5 dpi followed by a sharp decline at 7 dpi. All viruses caused a significant decline in body weight gain of birds as compared to the negative control group. Both TARV and THRV strains replicated in tendons and produced histologic lesions consistent with tenosynovitis. Hepatic lesions were produced by THRV only and the virus was re-isolated from liver and spleen of inoculated birds fulfilling Koch’s postulates. The results of this study should be helpful in facilitating diagnosis and designing future mitigation plans.
    Schlagwörter Reoviridae ; arthritis ; birds ; body weight changes ; enteritis ; etiological agents ; gene dosage ; hepatitis ; histology ; industry ; intestines ; liver ; pathogenesis ; poults ; spleen ; tenosynovitis ; viruses ; Turkey arthritis reovirus ; turkey enteric reovirus ; turkey hepatitis reovirus ; RT-qPCR
    Sprache Englisch
    Erscheinungsverlauf 2022-0903
    Umfang p. 435-444.
    Erscheinungsort Taylor & Francis
    Dokumenttyp Artikel ; Online
    ZDB-ID 1476380-1
    ISSN 1465-3338 ; 0307-9457
    ISSN (online) 1465-3338
    ISSN 0307-9457
    DOI 10.1080/03079457.2022.2079474
    Datenquelle NAL Katalog (AGRICOLA)

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  7. Artikel: Stability of SARS‐CoV‐2 and other coronaviruses in the environment and on common touch surfaces and the influence of climatic conditions: A review

    Aboubakr, Hamada A / Sharafeldin, Tamer A / Goyal, Sagar M

    Transboundary and emerging diseases. 2021 Mar., v. 68, no. 2

    2021  

    Abstract: Although the unprecedented efforts the world has been taking to control the spread of the human coronavirus disease (COVID‐19) and its causative aetiology [severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)], the number of confirmed cases has ... ...

    Abstract Although the unprecedented efforts the world has been taking to control the spread of the human coronavirus disease (COVID‐19) and its causative aetiology [severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)], the number of confirmed cases has been increasing drastically. Therefore, there is an urgent need for devising more efficient preventive measures, to limit the spread of the infection until an effective treatment or vaccine is available. The preventive measures depend mainly on the understanding of the transmission routes of this virus, its environmental stability, and its persistence on common touch surfaces. Due to the very limited knowledge about SARS‐CoV‐2, we can speculate its stability in the light of previous studies conducted on other human and animal coronaviruses. In this review, we present the available data on the stability of coronaviruses (CoVs), including SARS‐CoV‐2, from previous reports to help understand its environmental survival. According to available data, possible airborne transmission of SARS‐CoV‐2 has been suggested. SARS‐CoV‐2 and other human and animal CoVs have remarkably short persistence on copper, latex and surfaces with low porosity as compared to other surfaces like stainless steel, plastics, glass and highly porous fabrics. It has also been reported that SARS‐CoV‐2 is associated with diarrhoea and that it is shed in the faeces of COVID‐19 patients. Some CoVs show persistence in human excrement, sewage and waters for a few days. These findings suggest a possible risk of faecal–oral, foodborne and waterborne transmission of SARS‐CoV‐2 in developing countries that often use sewage‐polluted waters in irrigation and have poor water treatment systems. CoVs survive longer in the environment at lower temperatures and lower relative humidity. It has been suggested that large numbers of COVID‐19 cases are associated with cold and dry climates in temperate regions of the world and that seasonality of the virus spread is suspected.
    Schlagwörter COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; airborne transmission ; cold ; copper ; diarrhea ; etiology ; feces ; glass ; humans ; irrigation ; latex ; porosity ; relative humidity ; risk ; sewage ; stainless steel ; vaccines ; viruses ; water treatment
    Sprache Englisch
    Erscheinungsverlauf 2021-03
    Umfang p. 296-312.
    Erscheinungsort John Wiley & Sons, Ltd
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean ; REVIEW
    ZDB-ID 2414822-2
    ISSN 1865-1682 ; 1865-1674
    ISSN (online) 1865-1682
    ISSN 1865-1674
    DOI 10.1111/tbed.13707
    Datenquelle NAL Katalog (AGRICOLA)

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  8. Artikel: Stability of SARS-CoV-2 and other coronaviruses in the environment and on common touch surfaces and the influence of climatic conditions: A review

    Aboubakr, Hamada A / Sharafeldin, Tamer A / Goyal, Sagar M

    Transbound. emerg. dis. (Internet)

    Abstract: Although the unprecedented efforts the world has been taking to control the spread of the human coronavirus disease (COVID-19) and its causative aetiology [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)], the number of confirmed cases has ... ...

    Abstract Although the unprecedented efforts the world has been taking to control the spread of the human coronavirus disease (COVID-19) and its causative aetiology [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)], the number of confirmed cases has been increasing drastically. Therefore, there is an urgent need for devising more efficient preventive measures, to limit the spread of the infection until an effective treatment or vaccine is available. The preventive measures depend mainly on the understanding of the transmission routes of this virus, its environmental stability, and its persistence on common touch surfaces. Due to the very limited knowledge about SARS-CoV-2, we can speculate its stability in the light of previous studies conducted on other human and animal coronaviruses. In this review, we present the available data on the stability of coronaviruses (CoVs), including SARS-CoV-2, from previous reports to help understand its environmental survival. According to available data, possible airborne transmission of SARS-CoV-2 has been suggested. SARS-CoV-2 and other human and animal CoVs have remarkably short persistence on copper, latex and surfaces with low porosity as compared to other surfaces like stainless steel, plastics, glass and highly porous fabrics. It has also been reported that SARS-CoV-2 is associated with diarrhoea and that it is shed in the faeces of COVID-19 patients. Some CoVs show persistence in human excrement, sewage and waters for a few days. These findings suggest a possible risk of faecal-oral, foodborne and waterborne transmission of SARS-CoV-2 in developing countries that often use sewage-polluted waters in irrigation and have poor water treatment systems. CoVs survive longer in the environment at lower temperatures and lower relative humidity. It has been suggested that large numbers of COVID-19 cases are associated with cold and dry climates in temperate regions of the world and that seasonality of the virus spread is suspected.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #628257
    Datenquelle COVID19

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  9. Artikel ; Online: Stability of SARS‐CoV‐2 and other coronaviruses in the environment and on common touch surfaces and the influence of climatic conditions

    Aboubakr, Hamada A. / Sharafeldin, Tamer A. / Goyal, Sagar M.

    Transboundary and Emerging Diseases ; ISSN 1865-1674 1865-1682

    A review

    2020  

    Schlagwörter General Immunology and Microbiology ; General Veterinary ; General Medicine ; covid19
    Sprache Englisch
    Verlag Wiley
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    DOI 10.1111/tbed.13707
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Buch ; Online: Stability of SARS-CoV2 and other coronaviruses in the environment and on common touch surfaces and the influence of climatic conditions

    Aboubakr, Hamada / Sharafeldin, Tamer A / Goyal, Sagar M.

    a review

    2020  

    Abstract: Although the unprecedented efforts the world has been taking to control the spread of the humancoronavirus disease (COVID-19) and its causative etiology [Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)], the number of confirmed cases has ... ...

    Abstract Although the unprecedented efforts the world has been taking to control the spread of the humancoronavirus disease (COVID-19) and its causative etiology [Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)], the number of confirmed cases has been increasing drastically.Therefore, there is an urgent need for devising more efficient preventive measures, to limit the spreadof the infection until an effective treatment or vaccine is available. The preventive measures dependmainly on the understanding of the transmission routes of this virus, its environmental stability, andits persistence on common touch surfaces. Due to the very limited knowledge about SARS-CoV-2,we can speculate its stability in the light of previous studies conducted on other human and animalcoronaviruses. In this review, we present the available data on the stability of coronaviruses (CoVs),including SARS-CoV-2, from previous reports to help understand its environmental survival.According to available data, possible airborne transmission of SARS-CoV-2 has been suggested.SARS-CoV-2 and other human and animal CoVs have remarkably short persistence on copper, latex,and surfaces with low porosity as compared to other surfaces like stainless steel, plastics, glass, andhighly porous fabrics. It has also been reported that SARS-CoV-2 is associated with diarrhea and thatit is shed in the feces of COVID-19 patients. Some CoVs show persistence in human excrement,sewage, and waters for a few days. These findings suggest a possible risk of fecal-oral, foodborne,and waterborne transmission of SARS-CoV-2 in developing countries that often use sewage-pollutedwaters in irrigation and have poor water treatment systems. CoVs survive longer in the environment atlower temperatures and lower relative humidity. It has been suggested that large numbers of COVID-19 cases are associated with cold and dry climates in temperate regions of the world and thatseasonality of the virus spread is suspected.
    Schlagwörter covid19
    Verlag Center for Open Science
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    DOI 10.31219/osf.io/y2rth
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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