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  1. Article ; Online: A comprehensive review of beetroot (Beta vulgaris L.) bioactive components in the food and pharmaceutical industries

    Thiruvengadam, Muthu / Chung, Ill-Min / Samynathan, Ramkumar / Chandar, S. R. Harish / Venkidasamy, Baskar / Sarkar, Tanmay / Rebezov, Maksim / Gorelik, Olga / Shariati, Mohammad Ali / Simal-Gandara, Jesus

    Critical Reviews in Food Science and Nutrition. 2024 Jan. 25, v. 64, no. 3 p.708-739

    2024  

    Abstract: Beetroot is rich in various bioactive phytochemicals, which are beneficial for human health and exert protective effects against several disease conditions like cancer, atherosclerosis, etc. Beetroot has various therapeutic applications, including ... ...

    Abstract Beetroot is rich in various bioactive phytochemicals, which are beneficial for human health and exert protective effects against several disease conditions like cancer, atherosclerosis, etc. Beetroot has various therapeutic applications, including antioxidant, antibacterial, antiviral, and analgesic functions. Besides the pharmacological effects, food industries are trying to preserve beetroots or their phytochemicals using various food preservation methods, including drying and freezing, to preserve their antioxidant capacity. Beetroot is a functional food due to valuable active components such as minerals, amino acids, phenolic acid, flavonoid, betaxanthin, and betacyanin. Due to its stability, nontoxic and non-carcinogenic and nonpoisonous capabilities, beetroot has been used as an additive or preservative in food processing. Beetroot and its bioactive compounds are well reported to possess antioxidant, anti-inflammatory, antiapoptotic, antimicrobial, antiviral, etc. In this review, we provided updated details on (i) food processing, preservation and colorant methods using beetroot and its phytochemicals, (ii) synthesis and development of several nanoparticles using beetroot and its bioactive compounds against various diseases, (iii) the role of beetroot and its phytochemicals under disease conditions with molecular mechanisms. We have also discussed the role of other phytochemicals in beetroot and their health benefits. Recent technologies in food processing are also updated. We also addressed on molecular docking-assisted biological activity and screening for bioactive chemicals. Additionally, the role of betalain from different sources and its therapeutic effects have been listed. To the best of our knowledge, little or no work has been carried out on the impact of beetroot and its nanoformulation strategies for phytocompounds on antimicrobial, antiviral effects, etc. Moreover, epigenetic alterations caused by phytocompounds of beetroot under several diseases were not reported much. Thus, extensive research must be carried out to understand the molecular effects of beetroot in the near future.
    Keywords Beta vulgaris ; analgesics ; antioxidant activity ; antioxidants ; atherosclerosis ; beets ; betalains ; dyes ; epigenetics ; flavonoids ; food preservation ; functional foods ; human health ; nanoparticles ; nutrition ; phenolic acids ; therapeutics ; Beetroot ; betalain ; biomedical uses ; bioactive compounds ; molecular mechanisms ; food processing
    Language English
    Dates of publication 2024-0125
    Size p. 708-739.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2022.2108367
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Biological activity and development of functional foods fortified with okra (Abelmoschus esculentus)

    Agregán, Rubén / Pateiro, Mirian / Bohrer, Benjamin M. / Shariati, Mohammad Ali / Nawaz, Asad / Gohari, Gholamreza / Lorenzo, José M.

    Critical Reviews in Food Science and Nutrition. 2023 Sept. 10, v. 63, no. 23 p.6018-6033

    2023  

    Abstract: The Abelmoschus esculentus plant, better known as okra, is an interesting crop from a nutritional standpoint. The okra plant is native to the African region but can now be found throughout tropical and subtropical areas of the world. This plant, known ... ...

    Abstract The Abelmoschus esculentus plant, better known as okra, is an interesting crop from a nutritional standpoint. The okra plant is native to the African region but can now be found throughout tropical and subtropical areas of the world. This plant, known for its healing abilities, has been used as a traditional medicine to treat several diseases and external ailments, such as wounds or boils. This article reviews the potential health benefits from okra consumption, as well as the bioactive compounds that are suggested to be responsible. Furthermore, the okra plant and its derivatives have been evaluated in the formulation and manufacture of new functional food products. The latest advances in this direction, which includes characterizing the technical properties of functional foods fortified with okra are also presented in this review. A series of bioactive compounds such as flavonoids and catechins have been found in the okra plant, which were associated with numerous biological properties observed in research studies that reported potential anti-diabetic, anti-cancer, anti-hypertensive, and antimicrobial effects, among others, as a result of their consumption. These potential health benefits contribute to the development of new and useful functional foods, with okra (or its derivatives) being used as the highlighted ingredient.
    Keywords Abelmoschus esculentus ; bioactive properties ; flavanols ; food science ; functional foods ; ingredients ; manufacturing ; nutrition ; okra ; traditional medicine ; Phenolic compound ; polysaccharide ; biological property ; disease ; functional food
    Language English
    Dates of publication 2023-0910
    Size p. 6018-6033.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2022.2026874
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Nature's palette: An emerging frontier for coloring dairy products.

    Ghosh, Susmita / Sarkar, Tanmay / Chakraborty, Runu / Shariati, Mohammad Ali / Simal-Gandara, Jesus

    Critical reviews in food science and nutrition

    2022  Volume 64, Issue 6, Page(s) 1508–1552

    Abstract: Consumers all across the world are looking for the most delectable and appealing foods, while also demanding products that are safer, more nutritious, and healthier. Substitution of synthetic colorants with natural colorants has piqued consumer and ... ...

    Abstract Consumers all across the world are looking for the most delectable and appealing foods, while also demanding products that are safer, more nutritious, and healthier. Substitution of synthetic colorants with natural colorants has piqued consumer and market interest in recent years. Due to increasing demand, extensive research has been conducted to find natural and safe food additives, such as natural pigments, that may have health benefits. Natural colorants are made up of a variety of pigments, many of which have significant biological potential. Because of the promising health advantages, natural colorants are gaining immense interest in the dairy industry. This review goes over the use of various natural colorants in dairy products which can provide desirable color as well as positive health impacts. The purpose of this review is to provide an in-depth look into the field of food (natural or synthetic) colorants applied in dairy products as well as their potential health benefits, safety, general trends, and future prospects  in food science and technology. In this paper, we listed a plethora of applications of natural colorants in various milk-based products.
    MeSH term(s) Food Coloring Agents/analysis ; Pigments, Biological ; Food Additives ; Food Technology ; Dairy Products
    Chemical Substances Food Coloring Agents ; Pigments, Biological ; Food Additives
    Language English
    Publishing date 2022-09-06
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2022.2117785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: S-Allylcysteine (SAC) Exerts Renoprotective Effects via Regulation of TGF- β1/Smad3 Pathway Mediated Matrix Remodeling in Chronic Renal Failure.

    Samynathan, Ramkumar / Subramanian, Umadevi / Venkidasamy, Baskar / Shariati, Mohammad Ali / Chung, Ill-Min / Thiruvengadam, Muthu

    Current pharmaceutical design

    2022  Volume 28, Issue 8, Page(s) 661–670

    Abstract: Background: S-Allylcysteine (SAC), an organosulfur phytochemical sourced from aged garlic extract, is well known for its varied biomedical applications, such as anti-oxidant, anti-inflammatory, and detoxification mechanisms. Despite this, the scientific ...

    Abstract Background: S-Allylcysteine (SAC), an organosulfur phytochemical sourced from aged garlic extract, is well known for its varied biomedical applications, such as anti-oxidant, anti-inflammatory, and detoxification mechanisms. Despite this, the scientific findings on the defensive impact of SAC against kidney failure (KF) are still unclear. Therefore, in the current investigation, the animal model of KF was induced by adenine in Wistar rats, and the animals were divided into four groups as control, KF induction using adenine, SAC treated KF rats for an experimental duration of 8 weeks.
    Methods: KF progression was assessed by various serum and tissue markers, and the results demonstrated that the renal functions' markers, KIM-1 (kidney injury molecule-1), cystatin, NGAL (neutrophil gelatinase-associated lipocalin), were found increased in adenine-treated rats compared to control. In addition, the inflammatory markers, matrix proteins, and fibrosis signatures explicated by RT-PCR, ELISA demonstrated a profound increase. On the other hand, rats received SAC mitigated KF considerably (p < 0.001) with restored cellular functions. Besides, SAC pre-treatment abrogated the cytokines and pro-inflammatory signals (COX-2 and PGE2) in a dose-dependent manner.
    Conclusion: Furthermore, the fibrosis signaling markers mediators, such as SMAD-2,-3 were increased with associated matrix proteins. Thus, the present study substantiated that SAC possesses a significant renoprotective effect that might have been demonstrated by the inhibition of the TGF-β1/Smad3 signaling pathway.
    MeSH term(s) Adenine/pharmacology ; Aged ; Animals ; Cysteine/analogs & derivatives ; Fibrosis ; Humans ; Kidney Failure, Chronic ; Rats ; Rats, Wistar ; Renal Insufficiency, Chronic ; Smad Proteins/metabolism ; Smad3 Protein/metabolism ; Transforming Growth Factor beta1/metabolism
    Chemical Substances SMAD3 protein, human ; Smad Proteins ; Smad3 Protein ; Transforming Growth Factor beta1 ; S-allylcysteine (81R3X99M15) ; Adenine (JAC85A2161) ; Cysteine (K848JZ4886)
    Language English
    Publishing date 2022-03-30
    Publishing country United Arab Emirates
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/1381612828666220401114301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Beyond Conventional Meat Preservation: Saddling the Control of Bacteriocin and Lactic Acid Bacteria for Clean Label and Functional Meat Products.

    Smaoui, Slim / Echegaray, Noemí / Kumar, Manoj / Chaari, Moufida / D'Amore, Teresa / Shariati, Mohammad Ali / Rebezov, Maksim / Lorenzo, Jose Manuel

    Applied biochemistry and biotechnology

    2023  

    Abstract: Advancements in food science and technology have paved the way for the development of natural antimicrobial compounds to ensure the safety and quality of meat and meat products. Among these compounds, bacteriocin produced by lactic acid bacteria has ... ...

    Abstract Advancements in food science and technology have paved the way for the development of natural antimicrobial compounds to ensure the safety and quality of meat and meat products. Among these compounds, bacteriocin produced by lactic acid bacteria has gained considerable scientific attention for its ability to preserve the healthy properties of meat while preventing spoilage. This natural preservative is seen as a pioneering tool and a potent alternative to chemical preservatives and heat treatment, which can have harmful effects on the nutritional and sensory qualities of meat. Bacteriocin produced by lactic acid bacteria can be used in various forms, including as starter/protective cultures for fermented meats, purified or partially purified forms, loaded in active films/coatings, or established in encapsulate systems. This review delves into the downstream purification schemes of LAB bacteriocin, the elucidation of their characteristics, and their modes of action. Additionally, the application of LAB bacteriocins in meat and meat products is examined in detail. Overall, the use of LAB bacteriocins holds immense potential to inspire innovation in the meat industry, reducing the dependence on harmful chemical additives and minimizing the adverse effects of heat treatment on nutritional and sensory qualities. This review provides a comprehensive understanding of the potential of bacteriocin produced by lactic acid bacteria as a natural and effective meat preservative.
    Language English
    Publishing date 2023-08-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 392344-7
    ISSN 1559-0291 ; 0273-2289
    ISSN (online) 1559-0291
    ISSN 0273-2289
    DOI 10.1007/s12010-023-04680-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Essential Oils Composition and Biological Activity of

    Eltayeb, Loai M H / Yagi, Sakina / Mohamed, Hanan M M / Zengin, Gokhan / Shariati, Mohammad Ali / Rebezov, Maksim / Uba, Abdullah Ibrahim / Lorenzo, Jose Manuel

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 3

    Abstract: Generally, there are scant data about the constituents and eventually the biological activity of essential oils (EOs) from aromatic plants that grow naturally in Sudan. The present study aimed to determine the chemical composition, and antioxidant and ... ...

    Abstract Generally, there are scant data about the constituents and eventually the biological activity of essential oils (EOs) from aromatic plants that grow naturally in Sudan. The present study aimed to determine the chemical composition, and antioxidant and enzyme inhibitory activities of EO extracted from the fruit of
    MeSH term(s) Oils, Volatile/pharmacology ; Oils, Volatile/chemistry ; Lavandula/chemistry ; Chamaecyparis/chemistry ; Chrysopogon ; Sudan ; Butyrylcholinesterase ; Monoterpenes ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Sesquiterpenes/pharmacology
    Chemical Substances Oils, Volatile ; Butyrylcholinesterase (EC 3.1.1.8) ; Monoterpenes ; Antioxidants ; Sesquiterpenes
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28031005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Medicinal Plants for Viral Respiratory Diseases: A Systematic Review on Persian Medicine.

    Hajimonfarednejad, Mahdie / Ostovar, Mohadeseh / Hasheminasab, Fatemeh Sadat / Shariati, Mohammad Ali / Thiruvengadam, Muthu / Raee, Mohammad Javad / Hashempur, Mohammad Hashem

    Evidence-based complementary and alternative medicine : eCAM

    2023  Volume 2023, Page(s) 1928310

    Abstract: Introduction: Many medicinal plants have been introduced in Persian medicine references for various respiratory disorders. Considering the growing interest in herbal medicines, this review aimed to introduce medicinal herbs recommended by Persian ... ...

    Abstract Introduction: Many medicinal plants have been introduced in Persian medicine references for various respiratory disorders. Considering the growing interest in herbal medicines, this review aimed to introduce medicinal herbs recommended by Persian Medicine (PM) references for respiratory diseases and to discuss their activity against respiratory viruses.
    Methods: The medicinal plants recommended for respiratory disorders were extracted from the main PM textbooks. Subsequently, their activity against respiratory viruses was systematically investigated via queries of scientific databases.
    Results: Searching PM references for medicinal plants used in the management of respiratory disorders yielded 45 results. Of them, 18 possess antiviral activity against respiratory viruses. There were 29 in vitro studies (including studies on human cell lines) and 5 in vivo studies.
    Conclusion: This research demonstrated that many of the medicinal plants mentioned for the respiratory diseases in PM have considerable activity against respiratory viruses. However, human studies regarding the reported medicinal plants are scarce.
    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2023/1928310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Herbal remedies in the management of hyperuricemia and gout: A review of in vitro, in vivo and clinical evidences.

    Mahomoodally, Mohamad Fawzi / Coodian, Kaisavadee / Hosenally, Muzzammil / Zengin, Gokhan / Shariati, Mohammad Ali / Abdalla, Ashraf N / Alhazmi, Hassan A / Khuwaja, Gulrana / Mohan, Syam / Khalid, Asaad

    Phytotherapy research : PTR

    2024  

    Abstract: Gout, or hyperuricemia is a multifactorial and multi-faceted metabolic disease that is quite difficult to manage and/or treat. Conventional therapies such as non-steroidal anti-inflammatory drugs (NSAIDs) such as allopurinol, corticosteroids and ... ...

    Abstract Gout, or hyperuricemia is a multifactorial and multi-faceted metabolic disease that is quite difficult to manage and/or treat. Conventional therapies such as non-steroidal anti-inflammatory drugs (NSAIDs) such as allopurinol, corticosteroids and colchicine amongst others, have helped in its management and treatment to some extent. This study aimed to compile and analyze the different herbal remedies used in the management of hyperuricemia and gout. A literature search was conducted from key databases (PubMed, ScienceDirect, Cochrane Library, Google Scholar) using relevant keywords via the PRISMA model. Smilax riparia A.DC. from Traditional Chinese Medicine is used in many countries for its therapeutic effect on lowering serum urate levels. No single study was able to establish the efficacy of a specific traditionally used herb via in vitro, in vivo, and clinical studies. Patients were found to use a panoply of natural remedies, mainly plants to treat hyperuricemia and gout, which have been validated to some extent by in vitro, in vivo, and clinical studies. Nonetheless, further research is needed to better understand the ethnopharmacological relationship of such herbal remedies.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.8211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Application of bio-inspired optimization algorithms in food processing

    Sarkar, Tanmay / Salauddin, Molla / Mukherjee, Alok / Shariati, Mohammad Ali / Rebezov, Maksim / Tretyak, Lyudmila / Pateiro, Mirian / Lorenzo, José M.

    Current research in food science. 2022, v. 5

    2022  

    Abstract: Bio-inspired optimization techniques (BOT) are part of intelligent computing techniques. There are several BOTs available and many new BOTs are evolving in this era of industrial revolution 4.0. Genetic algorithm, particle swarm optimization, artificial ... ...

    Abstract Bio-inspired optimization techniques (BOT) are part of intelligent computing techniques. There are several BOTs available and many new BOTs are evolving in this era of industrial revolution 4.0. Genetic algorithm, particle swarm optimization, artificial bee colony, and grey wolf optimization are the techniques explored by researchers in the field of food processing technology. Although, there are other potential methods that may efficiently solve the optimum related problem in food industries. In this review, the mathematical background of the techniques, their application and the potential microbial-based optimization methods with higher precision has been surveyed for a complete and comprehensive understanding of BOTs along with their mechanism of functioning. These techniques can simulate the process efficiently and able to find the near-to-optimal value expeditiously.
    Keywords algorithms ; research ; wolves
    Language English
    Size p. 432-450.
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 2665-9271
    DOI 10.1016/j.crfs.2022.02.006
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Allergen30: Detecting Food Items with Possible Allergens Using Deep Learning-Based Computer Vision

    Mishra, Mayank / Sarkar, Tanmay / Choudhury, Tanupriya / Bansal, Nikunj / Smaoui, Slim / Rebezov, Maksim / Shariati, Mohammad Ali / Lorenzo, José M.

    Food Anal. Methods. 2022 Nov., v. 15, no. 11 p.3045-3078

    2022  

    Abstract: Food allergies impose a significant health concern on the community. A small number of certain food items can cause an allergic reaction within the human body. The symptoms can range from mild hives or itchiness to life-threatening anaphylaxis. In most ... ...

    Abstract Food allergies impose a significant health concern on the community. A small number of certain food items can cause an allergic reaction within the human body. The symptoms can range from mild hives or itchiness to life-threatening anaphylaxis. In most cases, such reactions can be prevented by simply being aware of the allergen-based food items and avoiding the consumption of the same. We are among the first research attempts to train a deep learning–based object detection model to detect the presence of such food items within an image. We introduce our Allergen30 dataset, which hosts more than 6,000 annotated images of 30 commonly used food items that can trigger an adverse reaction. We report the comparison of multiple variants of the current state-of-art object detection methods, YOLOv5 and YOLOR. Furthermore, we qualitatively analyzed the performance of these methods by surveying the predictions made on the test dataset images.
    Keywords adverse effects ; anaphylaxis ; computer vision ; data collection ; humans ; models
    Language English
    Dates of publication 2022-11
    Size p. 3045-3078.
    Publishing place Springer US
    Document type Article ; Online
    ZDB-ID 2429656-9
    ISSN 1936-976X ; 1936-9751
    ISSN (online) 1936-976X
    ISSN 1936-9751
    DOI 10.1007/s12161-022-02353-9
    Database NAL-Catalogue (AGRICOLA)

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