LIVIVO - Search results -

Search results

Result 1 - 10 of total 252

Search options

Article ; Online: Crossmodal plasticity in hearing loss.

Kral, Andrej / Sharma, Anu

2023 Volume 46, Issue 5, Page(s) 377–393

Abstract: Crossmodal plasticity is a textbook example of the ability of the brain to reorganize based on use. We review evidence from the auditory system showing that such reorganization has significant limits, is dependent on pre-existing circuitry and top-down ... ...

Abstract	Crossmodal plasticity is a textbook example of the ability of the brain to reorganize based on use. We review evidence from the auditory system showing that such reorganization has significant limits, is dependent on pre-existing circuitry and top-down interactions, and that extensive reorganization is often absent. We argue that the evidence does not support the hypothesis that crossmodal reorganization is responsible for closing critical periods in deafness, and crossmodal plasticity instead represents a neuronal process that is dynamically adaptable. We evaluate the evidence for crossmodal changes in both developmental and adult-onset deafness, which start as early as mild-moderate hearing loss and show reversibility when hearing is restored. Finally, crossmodal plasticity does not appear to affect the neuronal preconditions for successful hearing restoration. Given its dynamic and versatile nature, we describe how this plasticity can be exploited for improving clinical outcomes after neurosensory restoration.
MeSH term(s)	Adult ; Humans ; Auditory Cortex/physiology ; Acoustic Stimulation ; Photic Stimulation ; Hearing Loss ; Deafness ; Neuronal Plasticity/physiology
Language	English
Publishing date	2023-03-27
Publishing country	England
Document type	Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	282488-7
ISSN	1878-108X ; 0378-5912 ; 0166-2236
ISSN (online)	1878-108X
ISSN	0378-5912 ; 0166-2236
DOI	10.1016/j.tins.2023.02.004
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1442: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 53: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Risk Factors for Fragility Fractures in Chronic Lymphocytic Leukemia.

Petty, Lloyd / Stephens, Deborah / Sharma, Anu

Cureus

2024 Volume 16, Issue 2, Page(s) e54774

Abstract: Abnormal bone health and fragility fractures (FF) are more common in patients with chronic lymphocytic leukemia (CLL). We hypothesize that there may be risk factors in CLL patients with osteoporosis that increase the risk of FFs. We conducted a cohort ... ...

Abstract	Abnormal bone health and fragility fractures (FF) are more common in patients with chronic lymphocytic leukemia (CLL). We hypothesize that there may be risk factors in CLL patients with osteoporosis that increase the risk of FFs. We conducted a cohort study encompassing all patients diagnosed with CLL from January 1, 2000, to July 31, 2020, utilizing International Classification of Diseases (ICD) codes related to abnormal bone health (osteopenia, osteoporosis, and/or presence of FF) within a single tertiary care institution. Of the 89 patients included, 55 (62%) were female with a mean age of 68 ± 11 years at cohort entry. Fifty-nine (66%) had at least one FF present (pFF) and 30 (34%) did not have an FF (nFF). There were no differences in IGHV (Immunoglobulin heavy chain variable region gene) mutation status, chromosomal abnormalities, or the presence of a complex karyotype. The spine accounted for 81% of identified FF.
Language	English
Publishing date	2024-02-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.54774
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Optimization of enzyme aided pigment extraction from pumpkin (Cucurbita maxima Duch) using response surface methodology

Sharma, Anu / Sogi, Dalbir Singh

Journal of food measurement & characterization. 2022 Apr., v. 16, no. 2

2022

Abstract: Pumpkin’s bio-pigment is a natural source to improve the appearance of food products along with nutritional value. Present work aimed at optimizing the carotenoids extraction from pumpkin with enzymatic pre-treatment. A central composite design with four ...

Abstract	Pumpkin’s bio-pigment is a natural source to improve the appearance of food products along with nutritional value. Present work aimed at optimizing the carotenoids extraction from pumpkin with enzymatic pre-treatment. A central composite design with four independent variables-cellulose/pectinase ratio (0.25–1.91w/w); Incubation temperature (35–55 °C); Incubation time (30–150 min); pH (4–6) gave carotenoids yield of 0.689 to 3.820 mg/100 g. F-value of 39.07 and p value < 0.0001 shows that pigment extraction was adequately described by regression model. Linear coefficients of X₁, X₂, and X₄, (enzyme ratio, temperature, pH), quadratic coefficient of X₁², X₂², X₃², and X₄² (enzyme ratio, temperature, time and pH) and interaction coefficient of X₁X₂ (enzyme ratio and temperature) and X₂X₄ (temperature and pH) were also significant (p ≤ 0.05). The second order polynomial model had a non-significant lack of fitness, good value of coefficient of determination (0.973) and adequate scattered plot. Surface graph and Derringer’s desired function methodology were used to find the optimal conditions of carotenoids extraction. Maximum carotenoids were extracted when the cellulose/pectinase ratio, incubation temperature, incubation time and pH were 0.97w/w, 42.54 °C, 91.58 min and 4.8 respectively. The β-carotene extraction yield was 61.75% under the optimal conditions.
Keywords	cellulose ; mathematical models ; measurement ; nutritive value ; pH ; polygalacturonase ; pumpkins ; regression analysis ; response surface methodology ; temperature
Language	English
Dates of publication	2022-04
Size	p. 1184-1194.
Publishing place	Springer US
Document type	Article
ZDB-ID	2754612-3
ISSN	2193-4134 ; 2193-4126
ISSN (online)	2193-4134
ISSN	2193-4126
DOI	10.1007/s11694-021-01246-5
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Laryngological Symptomatology in Patients with Ehlers-Danlos Syndrome.

Sharma, Anu / Bryson, Paul C / Adessa, Michelle

The Laryngoscope

2023 Volume 134, Issue 2, Page(s) 894–896

Abstract: Laryngological manifestations of connective tissue diease with hypermobility such as ehlers-danlos syndrome (EDS) are not well defined in the literature. EDS is an inherited, hetrogeneous, connective tissue disorder characterized by joint hypermobility, ... ...

Abstract	Laryngological manifestations of connective tissue diease with hypermobility such as ehlers-danlos syndrome (EDS) are not well defined in the literature. EDS is an inherited, hetrogeneous, connective tissue disorder characterized by joint hypermobility, skin extensibility, and joint dislocations. A case series of 9 patients is presented with varying laryngological complaints. Common comorbities include postural orthostatic tachycardia syndrome (POTS), fibromyalgia, irritable bowel syndrome (IBS), and gastroesophageal reflux disease (GERD)/laryngopharyngeal reflux disease (LPRD). Six patients were singers. Videostroboscopic parameters and treatment courses are described. It may be beneficial to view patients with EDS and laryngological complaints through a holistic lens as many may need interdisciplinary assessment and management. Laryngoscope, 134:894-896, 2024.
MeSH term(s)	Humans ; Ehlers-Danlos Syndrome/complications ; Ehlers-Danlos Syndrome/diagnosis ; Postural Orthostatic Tachycardia Syndrome ; Gastroesophageal Reflux/complications ; Joint Instability
Language	English
Publishing date	2023-06-28
Publishing country	United States
Document type	Case Reports
ZDB-ID	80180-x
ISSN	1531-4995 ; 0023-852X
ISSN (online)	1531-4995
ISSN	0023-852X
DOI	10.1002/lary.30852
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ul II Zs.82: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Prioritizing research on over-the-counter (OTC) hearing aids for age-related hearing loss.

Manchaiah, Vinaya / Swanepoel, De Wet / Sharma, Anu

Frontiers in aging

2023 Volume 4, Page(s) 1105879

Abstract: Hearing aids are the most commonly used treatment for people with age-related hearing loss, however, hearing aid uptake is low, primarily due to high cost of the device, stigma, and a lack of perceived need. To address accessibility and affordability ... ...

Abstract	Hearing aids are the most commonly used treatment for people with age-related hearing loss, however, hearing aid uptake is low, primarily due to high cost of the device, stigma, and a lack of perceived need. To address accessibility and affordability issues, the U.S. Food and Drug Administration created a new over-the-counter (OTC) hearing aid category. Various types of hearing devices are available for both individuals with hearing loss and for those with normal hearing, as hearing enhancement devices. Hearing aids (i.e., prescription hearing aids, self-fitting OTC hearing aids, and pre-set OTC hearing aids) are regulated by the FDA. The purpose of this article is to (a) provide a summary of existing research on direct-to-consumer (DTC) hearing devices such as Personal Sound Amplification Products (PSAPs) that informs OTC service delivery models; (b) provide an update on existing and ongoing randomized controlled trials on currently marketed OTC hearing aids; and (c) highlight the need for immediate research on OTC hearing aids and service delivery models to inform policy and clinical care. It remains to be seen what effect OTC hearing aids have on improving the uptake of hearing aids by individuals with mild-to-moderate hearing loss. However, there is scant research on all aspects of OTC hearing aids that are currently on the market. We conclude that high quality independent research must be prioritized to supplement evidence provided by the OTC hearing aid manufacturers for regulatory approval purposes.
Language	English
Publishing date	2023-03-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	3076785-4
ISSN	2673-6217 ; 2673-6217
ISSN (online)	2673-6217
ISSN	2673-6217
DOI	10.3389/fragi.2023.1105879
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Practical Approach to Hyperandrogenism in Women.

Sharma, Anu / Welt, Corrine K

The Medical clinics of North America

2021 Volume 105, Issue 6, Page(s) 1099–1116

Abstract: The approach to hyperandrogenism in women varies depending on the woman's age and severity of symptoms. Once tumorous hyperandrogenism is excluded, the most common cause is PCOS. Hirsutism is the most common presenting symptom. The woman's concern about ... ...

Abstract	The approach to hyperandrogenism in women varies depending on the woman's age and severity of symptoms. Once tumorous hyperandrogenism is excluded, the most common cause is PCOS. Hirsutism is the most common presenting symptom. The woman's concern about her symptoms plays an important role in the management of disease. Although measurement of testosterone is useful in identifying an underlying cause, care must be taken when interpreting the less accurate assays that are available commercially. Surgical resection is curative in tumorous etiologies, whereas medical management is the mainstay for non-tumorous causes.
MeSH term(s)	Age Factors ; Androgen Antagonists/therapeutic use ; Female ; Humans ; Hyperandrogenism/diagnosis ; Hyperandrogenism/drug therapy ; Hyperandrogenism/etiology ; Hyperandrogenism/physiopathology ; Polycystic Ovary Syndrome/complications ; Racial Groups ; Testosterone/blood ; Women's Health
Chemical Substances	Androgen Antagonists ; Testosterone (3XMK78S47O)
Language	English
Publishing date	2021-09-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	215710-x
ISSN	1557-9859 ; 0025-7125
ISSN (online)	1557-9859
ISSN	0025-7125
DOI	10.1016/j.mcna.2021.06.008
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.158: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Digits-in-Noise Test as an Assessment Tool for Hearing Loss and Hearing Aids.

Schimmel, Carly / Cormier, Kayla / Manchaiah, Vinaya / Swanepoel, De Wet / Sharma, Anu

Audiology research

2024 Volume 14, Issue 2, Page(s) 342–358

Abstract: The aim of this study was to examine the relationship between an American English Digits in Noise (DIN) test and commonly used audiological measures to evaluate the DIN test's ability to detect hearing loss and validate hearing aid fitting. QuickSIN and ... ...

Abstract	The aim of this study was to examine the relationship between an American English Digits in Noise (DIN) test and commonly used audiological measures to evaluate the DIN test's ability to detect hearing loss and validate hearing aid fitting. QuickSIN and DIN tests were completed by participants with untreated hearing loss (
Language	English
Publishing date	2024-04-08
Publishing country	Switzerland
Document type	Journal Article
ISSN	2039-4330
ISSN	2039-4330
DOI	10.3390/audiolres14020030
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Evaluation of retinal function and morphology in isoametropic amblyopia.

Sharma, Pradeep / Anand, Mrinalini / Sharma, Anu / Phuljhele, Swati / Saxena, Rohit

Indian journal of ophthalmology

2023 Volume 71, Issue 1, Page(s) 222–228

Abstract: Purpose: To observe the photoreceptor anomalies in cases of ametropic amblyopia.: Methods: A prospective study with 25 isoametropic amblyopic children in the age group of 5-14 years and 25 age-matched controls was done. Examination included ... ...

Abstract	Purpose: To observe the photoreceptor anomalies in cases of ametropic amblyopia. Methods: A prospective study with 25 isoametropic amblyopic children in the age group of 5-14 years and 25 age-matched controls was done. Examination included refraction, best-corrected visual acuity (BCVA), and color vision. Adaptive optics (AO) and multifocal electroretinogram (mf-ERG) were done to assess the anatomy and function of photoreceptors. The subgroup analysis of the improved and non-improved groups was done. Results: The mean cone density in cases and control in the superior, temporal, and nasal quadrants was respectively as follows (21640 ± 5713, 24040 ± 3386, P = 0.01) (19755 ± 6282, 21832 ± 2911, P = 0.03) (19897 ± 5418, 22171 ± 3660, P = 0.01) (20768 ± 4799, 22819 ± 3241, P = 0.01). The amplitude of N1 wave and P1 wave in cases was significantly low compared to the controls. Cases with subnormal color vision had reduced BCVA (0.55 ± 0.018) in comparison to the children with normal response (0.350 ± 0.014). Cone density was also significantly reduced in children with subnormal color vision. Sixteen out of 25 cases showed BCVA improvement with spectacles. Baseline cone density was found to be significantly higher in the improved group. There was no correlation between BCVA and AO parameters. Conclusion: Patients with ametropic amblyopia show subnormal photoreceptor properties than controls. Low cone density may be associated with defective color vision and poor prognosis in these cases.
MeSH term(s)	Child ; Humans ; Child, Preschool ; Adolescent ; Amblyopia/diagnosis ; Visual Acuity ; Prospective Studies ; Retina/diagnostic imaging ; Refraction, Ocular ; Vision Disorders ; Vision, Low
Language	English
Publishing date	2023-01-06
Publishing country	India
Document type	Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/ijo.IJO_1685_22
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 329: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 598: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Auditory Cortex Maturation and Language Development in Children with Hearing Loss and Additional Disabilities.

Lamminmäki, Satu / Cormier, Kayla / Davidson, Hanna / Grigsby, Jim / Sharma, Anu

Children (Basel, Switzerland)

2023 Volume 10, Issue 11

Abstract: A significant portion of hearing-impaired children have additional disabilities, but data about the maturation of their auditory cortex are scarce. In these children, behavioral tests are often unreliable, and objective tests are needed for diagnostics ... ...

Abstract	A significant portion of hearing-impaired children have additional disabilities, but data about the maturation of their auditory cortex are scarce. In these children, behavioral tests are often unreliable, and objective tests are needed for diagnostics and follow-up. This study aimed to explore auditory cortical maturation and language development, and the usability of an objective electroencephalogram-based biomarker in children with multiple disabilities. In 65 hearing aid and cochlear implant users (36 females; 36 with multiple disabilities; 44.3 ± 18.5 months of age, mean ± SD), auditory processing was examined using the P1 cortical auditory evoked response biomarker, and language development with the Preschool Language Scales 5th edition (PLS-5). During the study, all of the children received intensive extra language therapy for six months. No significant differences were found between the groups in P1 latency development, the proportion of abnormal P1 latencies, or the number of children whose P1 latencies changed from abnormal to normal during the study. The PLS-5 total language scores, auditory comprehension scores, or expressive communication scores did not differ between groups either. The P1 latencies showed meaningful negative correlations with the language scores. The results suggest that auditory cortex development is similar in hearing-impaired children with/without additional disabilities, and the P1 biomarker is a feasible tool to evaluate central auditory maturation in children with multiple disabilities.
Language	English
Publishing date	2023-11-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2732685-8
ISSN	2227-9067
ISSN	2227-9067
DOI	10.3390/children10111813
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Face mask use in healthcare settings: effects on communication, cognition, listening effort and strategies for amelioration.

Lee, Emily / Cormier, Kayla / Sharma, Anu

Cognitive research: principles and implications

2022 Volume 7, Issue 1, Page(s) 2

Abstract: Aim: To investigate mask use and the difficulties it may pose during communication in healthcare settings.: Methods: A survey utilizing a series of Likert scales was administered. Mask use challenges between clinicians and their patients were ... ...

Abstract	Aim: To investigate mask use and the difficulties it may pose during communication in healthcare settings. Methods: A survey utilizing a series of Likert scales was administered. Mask use challenges between clinicians and their patients were examined in the domains of communication, listening effort, cognition, and rehabilitation. Results: Across 243 participants, mask use significantly increased listening effort, with hearing loss having an additive effect on listening effort. Listening effort was also significantly associated with more trouble understanding conversation, decreased interest in conversation, more difficulty connecting with patients, changes in cognition for both providers and patients, and changes in the clinical efficiency of providers. Hearing loss had an additive effect for trouble understanding conversations and changes in clinical efficiency. Conclusion: These results provide information about the clinical strain introduced from mask use in healthcare settings. Overall, results show that in healthcare settings there is increased cognitive load and listening effort for both patients and providers, as well as changes in clinical efficiency for providers when utilizing masks. These effects are often greater with hearing loss. Results showed that patients reported written and visual instructions would be most beneficial to include in appointments among the other rehabilitative strategies which are discussed.
MeSH term(s)	Cognition ; Communication ; Delivery of Health Care ; Humans ; Listening Effort ; Masks ; Speech Perception
Language	English
Publishing date	2022-01-10
Publishing country	England
Document type	Journal Article
ISSN	2365-7464
ISSN (online)	2365-7464
DOI	10.1186/s41235-021-00353-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED