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Book: AIDS awareness through community participation

Sharma, Meenu

an action research

2006

Author's details	Meenu Sharma
Language	English
Size	366 S. : Ill., graph. Darst.
Publisher	Kalpaz
Publishing place	Delhi
Publishing country	India
Document type	Book
HBZ-ID	HT015063934
ISBN	81-7835-471-3 ; 978-81-7835-471-2
Database	Catalogue ZB MED Medicine, Health

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Article: Challenges for Lower-Middle-Income Countries in Achieving Universal Healthcare: An Indian Perspective.

Sharma, Meenu G / Popli, Harvinder

Cureus

2023 Volume 15, Issue 1, Page(s) e33751

Abstract: Universal health coverage (UHC) by 2030 is a commitment of the global community adopted as Sustainable Development Goal 3.8. UHC, as defined by WHO, means all people have access to quality health services, when and where they need them, and without ... ...

Abstract	Universal health coverage (UHC) by 2030 is a commitment of the global community adopted as Sustainable Development Goal 3.8. UHC, as defined by WHO, means all people have access to quality health services, when and where they need them, and without financial hardship. However, low-income and lower-middle-income countries, faced with competing priorities, find themselves struggling to muster enough resources to steer towards this goal at the desired pace. India is the largest lower-middle-income country, accounting for almost 18% of the world's population. How it performs in moving towards this goal will have a significant impact on achieving UHC at a global level. India has witnessed noteworthy improvement in several health indicators and the UHC service coverage index in recent decades, but the progress on improving service capacity and access has been rather slow given the enormity of its population, scarcity of funds, grossly inadequate public infrastructure, shortage of trained workforce, disparate needs of various regions of the country, lack of healthcare system integration, changing disease demography, and slack regulatory framework. The recent push through National Health Mission aims to address some of these challenges; however, a fragmented health delivery structure ossified over decades has been slow to keep up with the requirements of the country's massive and diverse population. This paper discusses the inherent characteristics and key challenges faced by the healthcare delivery system of India in achieving UHC.
Language	English
Publishing date	2023-01-13
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.33751
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Continuity obstetric care demonstrates greater vaginal birth after caesarean success.

Facchetti, Georgina / Teo, Zhen / Sharma, Meenu / Budden, Aaron

The Australian & New Zealand journal of obstetrics & gynaecology

2024

Abstract: Background: Australia's caesarean rate is higher than Organisation for Economic Co-operation and Development (OECD) average, and is rising. Vaginal birth after caesarean (VBAC) is safe for selected women. Midwifery continuity of care (CoC) is associated ...

Abstract	Background: Australia's caesarean rate is higher than Organisation for Economic Co-operation and Development (OECD) average, and is rising. Vaginal birth after caesarean (VBAC) is safe for selected women. Midwifery continuity of care (CoC) is associated with higher rates of vaginal birth compared to other models; however, impacts on VBAC attempts and success are unknown. Aims: The primary aim was to determine if there is a difference in achieving VBAC between CoC and non-CoC (NCoC) models. The secondary aim was to determine if there is a difference in the proportion of women attempting VBAC between these models. Materials and methods: Retrospective review of antenatal records and birthing data of all women who birthed in 2021 with one or more previous caesareans. Women were included if they had two or fewer caesareans. Women were excluded if contraindications to VBAC existed. Results: There were 142/1109 (12.8%) women who had previous caesareans and were eligible to attempt VBAC. There were 47/109 (43.1%) women who attempted vaginal birth after one caesarean with 78.7% success. After one caesarean, women in CoC were more likely to achieve VBAC than NCoC (45.2% vs 26.1%; relative risk (RR) 1.76, 95% CI 1.04-3.00), although when stratified by private and midwifery CoC models, women in midwifery CoC models were more likely to be successful (private RR 0.69, 95% CI 0.23-2.07 vs midwifery RR 2.48, 95% CI 1.50-4.11). Women in CoC were more likely to attempt VBAC (54.7% vs 34.8%; RR 1.57, 95% CI 1.02-2.41), and receive counselling about VBAC (92.5% vs 62%; RR 1.48, 95% CI 1.41-3.11). Conclusion: CoC improves the rate of attempted and successful VBAC through several factors, including increased counselling and greater provision of birth choices.
Language	English
Publishing date	2024-01-05
Publishing country	Australia
Document type	Journal Article
ZDB-ID	390815-x
ISSN	1479-828X ; 0004-8666
ISSN (online)	1479-828X
ISSN	0004-8666
DOI	10.1111/ajo.13790
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Article: Iron Tungsten Nanorods Electrode with High Capacitance: An Extraordinary Cycling Stability for Durable Aqueous Supercapacitors

Sharma, Meenu / Bhargav, Atul

Energy & fuels. 2021 Dec. 20, v. 36, no. 1

2021

Abstract: Improving cycle life and rate capability through unique morphological features is beneficial for developing the energy storage capacity of supercapacitors (SC). The evolving use of abundant earth metals in low-cost metal tungstate (MWO₄) with superior ... ...

Abstract	Improving cycle life and rate capability through unique morphological features is beneficial for developing the energy storage capacity of supercapacitors (SC). The evolving use of abundant earth metals in low-cost metal tungstate (MWO₄) with superior specific capacitance and excellent stability in nontoxic electrolytes continues to be a challenge. This work develops nanorods (NRs) architectured iron tungsten (FeWO₄) electrode material for supercapacitors using a simple and industrially scalable method. The developed FeWO₄ nanorods display an excellent specific capacitance of 465 F g–¹ at a current density of 2 A g–¹ with an admirable 98% capacitive retention over 3000 cycles. The electrode’s diffusive and capacitive impacts are investigated for a detailed understanding. Next, an FeWO₄ NR-based symmetric supercapacitor was assembled in an aqueous electrolyte which displays areal capacitance of 116 mF cm–² in a potential window of 1.2 V. Surprisingly, the assembled device shows a capacitance retention of ∼93% over 50 000 continuous cycles with no noticeable changes in electrochemical behavior. Besides giving valuable insights toward the electrochemical properties of FeWO₄, this work demonstrates the potential of a device with exceptional stability in a nontoxic aqueous electrolyte that might compete with the most stable commercial carbon-based electrochemical capacitors.
Keywords	capacitance ; electrochemical capacitors ; electrochemistry ; electrodes ; electrolytes ; energy ; nanorods ; tungsten
Language	English
Dates of publication	2021-1220
Size	p. 618-625.
Publishing place	American Chemical Society
Document type	Article
ZDB-ID	1483539-3
ISSN	1520-5029 ; 0887-0624
ISSN (online)	1520-5029
ISSN	0887-0624
DOI	10.1021/acs.energyfuels.1c03102
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Patient satisfaction with access, affordability and quality of diabetes care at Mohalla Clinics in Delhi, India.

Sharma, Meenu Grover / Grover, Anu / Shekhawat, Kusum / Popli, Harvinder

Frontiers in public health

2023 Volume 11, Page(s) 1160408

Abstract: Introduction: Mohalla Clinics have been set up to provide curative care for minor ailments free of cost within walking distance in the urban slums, thus making primary care more accessible and affordable. Studies evaluating patient satisfaction with ... ...

Abstract	Introduction: Mohalla Clinics have been set up to provide curative care for minor ailments free of cost within walking distance in the urban slums, thus making primary care more accessible and affordable. Studies evaluating patient satisfaction with treatment of chronic conditions, such as diabetes, in these clinics are lacking. Methods: A survey of 400 type 2 diabetes patients was conducted, split equally between Mohalla clinics (MC) and Private clinics (PC) in Delhi. Responses were analyzed using STATA17, applying appropriate statistical tests for the data type (Chi-square test, Mann-Whitney Results: Satisfaction level was high in both groups with no significant difference between mean satisfaction scores of MC patients and PC patients (Mean 3.79 vs. 3.85 respectively, Conclusion: Mohalla clinics are making diabetes treatment accessible and affordable for the marginalized population of Delhi, despite not being designed or fully equipped to care for chronic diseases such as diabetes that require multi-specialty care to monitor and manage multiple co-morbidities and long-term complications. Positive perception of physician interaction and convenient location of the clinics are the two major contributors to the high satisfaction patients expressed with diabetes care at these clinics.
MeSH term(s)	Humans ; Patient Satisfaction ; Diabetes Mellitus, Type 2/therapy ; Blood Glucose Self-Monitoring ; Blood Glucose ; Treatment Outcome
Chemical Substances	Blood Glucose
Language	English
Publishing date	2023-04-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1160408
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Article ; Online: Designing of Carbon Nitride Supported ZnCo

Sharma, Meenu / Gaur, Anurag

Scientific reports

2020 Volume 10, Issue 1, Page(s) 2035

Abstract: This study reports a unique graphitic- ... ...

Abstract	This study reports a unique graphitic-C
Language	English
Publishing date	2020-02-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-58925-4
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Article: Genetic interaction between RLM1 and F-box motif encoding gene SAF1 contributes to stress response in Saccharomyces cerevisiae.

Sharma, Meenu / Verma, V / Bairwa, Narendra K

Genes and environment : the official journal of the Japanese Environmental Mutagen Society

2021 Volume 43, Issue 1, Page(s) 45

Abstract: Background: Stress response is mediated by the transcription of stress-responsive genes. The F-box motif protein Saf1p is involved in SCF-E3 ligase mediated degradation of the adenine deaminase, Aah1p upon nutrient stress. The four transcription ... ...

Abstract	Background: Stress response is mediated by the transcription of stress-responsive genes. The F-box motif protein Saf1p is involved in SCF-E3 ligase mediated degradation of the adenine deaminase, Aah1p upon nutrient stress. The four transcription regulators, BUR6, MED6, SPT10, SUA7, are listed for SAF1 in the genome database of Saccharomyces cerevisiae. Here in this study, we carried out an in-silico analysis of gene expression and transcription factor databases to understand the regulation of SAF1 expression during stress for hypothesis and experimental analysis. Result: An analysis of the GEO profile database indicated an increase in SAF1 expression when cells were treated with stress agents such as Clioquinol, Pterostilbene, Gentamicin, Hypoxia, Genotoxic, desiccation, and heat. The increase in expression of SAF1 during stress conditions correlated positively with the expression of RLM1, encoding the Rlm1p transcription factor. The expression of AAH1 encoding Aah1p, a Saf1p substrate for ubiquitination, appeared to be negatively correlated with the expression of RLM1 as revealed by an analysis of the Yeastract expression database. Based on analysis of expression profile and regulatory association of SAF1 and RLM1, we hypothesized that inactivation of both the genes together may contribute to stress tolerance. The experimental analysis of cellular growth response of cells lacking both SAF1 and RLM1 to selected stress agents such as cell wall and osmo-stressors, by spot assay indicated stress tolerance phenotype similar to parental strain however sensitivity to genotoxic and microtubule depolymerizing stress agents. Conclusions: Based on in-silico and experimental data we suggest that SAF1 and RLM1 both interact genetically in differential response to genotoxic and general stressors.
Language	English
Publishing date	2021-10-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2269162-5
ISSN	1880-7062 ; 1880-7046
ISSN (online)	1880-7062
ISSN	1880-7046
DOI	10.1186/s41021-021-00218-x
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Article ; Online: A Simple Assay for the Detection of Late-Stage Apoptosis Features in Saccharomyces cerevisiae.

Bairwa, Narendra K / Shoket, Heena / Pandita, Monika / Sharma, Meenu

Current protocols

2022 Volume 2, Issue 9, Page(s) e525

Abstract: Unicellular eukaryotic organisms such as yeast and protozoa serve as useful models for studying the impact of chemicals on cell physiology, cellular growth, and genome duplication. The yeast Saccharomyces cerevisiae has been widely used to assess ... ...

Abstract	Unicellular eukaryotic organisms such as yeast and protozoa serve as useful models for studying the impact of chemicals on cell physiology, cellular growth, and genome duplication. The yeast Saccharomyces cerevisiae has been widely used to assess apoptosis induced by chemicals due to its genetic tractability, ease of evaluation, and readily available impact assessment tools. Apoptosis in S. cerevisiae is characterized by many features, including increased cell death, loss of membrane integrity, release of caspases, chromatin condensation, and nuclear fragmentation, which are similar to the ones observed in mammalian cells. Current methods of apoptosis assessment typically require specialized equipment and reagents, which limits wide adoption. Here, we describe a rapid, inexpensive, and easy-to-perform assay in yeast for the analysis of late-stage apoptotic features in cells treated with a chemical. We describe a protocol for assessing loss of cell survival and changes in the nucleus. We demonstrate the approach by using acetic acid and hydrogen peroxide as test chemicals. This assay for the study of late-stage apoptotic features in S. cerevisiae can be performed reliably and rapidly by any laboratory with basic equipment and may be extended for studying apoptosis in similar single-cell organisms after treatment with toxicological agents. © 2022 Wiley Periodicals LLC. Basic Protocol 1: Culture of Saccharomyces cerevisiae, treatment with acetic acid or hydrogen peroxide, and semi-quantitative growth assay Basic Protocol 2: DAPI staining and fluorescence microscopy for the assessment of change in nucleus-to-cytoplasm ratio and nuclear integrity.
MeSH term(s)	Acetic Acid/metabolism ; Animals ; Apoptosis/physiology ; Caspases/metabolism ; Hydrogen Peroxide/metabolism ; Mammals/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics
Chemical Substances	Saccharomyces cerevisiae Proteins ; Hydrogen Peroxide (BBX060AN9V) ; Caspases (EC 3.4.22.-) ; Acetic Acid (Q40Q9N063P)
Language	English
Publishing date	2022-09-07
Publishing country	United States
Document type	Journal Article
ISSN	2691-1299
ISSN (online)	2691-1299
DOI	10.1002/cpz1.525
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Article: Family Psychoeducation as an Intervention Tool in the Management of Schizophrenia and the Psychological Wellbeing of Caregivers.

Sharma, Meenu / Srivastava, Shikha / Pathak, Abhijit

Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

2021 Volume 46, Issue 2, Page(s) 304–308

Abstract: Background: Caregivers need to be imparted with specialized skills to retain their psychological well-being and to manage the patient with schizophrenia effectively.: Aim: This study aims to understand the role of family psychoeducation (FPE) in the ... ...

Abstract	Background: Caregivers need to be imparted with specialized skills to retain their psychological well-being and to manage the patient with schizophrenia effectively. Aim: This study aims to understand the role of family psychoeducation (FPE) in the management of schizophrenia and the well-being of caregiver. Materials and methods: The sample included 40 caregivers and patients, 20 each assigned randomly in treatment group (psychoeducation given) and the control group. Pre and post assessment of psychological wellbeing (PWB), symptoms of the patient, and emotional regulation was done through the scales mentioned in the study and analyzed through analysis of variance. Results: Statistically significant improvement in emotional regulation of caregivers and patient ( Conclusion: FPE was found to be effective in improving PWB of caregivers and effective management of a patient with schizophrenia.
Language	English
Publishing date	2021-05-29
Publishing country	India
Document type	Journal Article
ZDB-ID	2085330-0
ISSN	1998-3581 ; 0970-0218
ISSN (online)	1998-3581
ISSN	0970-0218
DOI	10.4103/ijcm.IJCM_683_20
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Article ; Online: An unusual location of solitary fibrous tumor in heart-A case report and review of literature.

Fain, Kristen / Parmar, Kanak / Sharma, Meenu / Horn, Robert / Sethi, Pooja

Cancer reports (Hoboken, N.J.)

2022 Volume 5, Issue 11, Page(s) e1698

Abstract: Background: Solitary fibrous tumor (SFT) are rare spindle cell tumors originating from the mesenchymal cells mostly from the visceral pleura. SFT was first described as a distinct entity in 1931 by Klemperer et al. Until now, we have limited data ... ...

Abstract	Background: Solitary fibrous tumor (SFT) are rare spindle cell tumors originating from the mesenchymal cells mostly from the visceral pleura. SFT was first described as a distinct entity in 1931 by Klemperer et al. Until now, we have limited data regarding the manifestation and behavior of extra pleural forms such as cardiac SFT. Here we present a case of SFT involving the pericardium where the diagnosis was made by imaging followed by biopsy findings. We also review the literature of SFT involving the heart and the management approaches. Case presentation: An 81-year-old male presented with progressive dyspnea. Computed tomography (CT) of the chest showed a 6.2 × 5.3 cm soft tissue mass in the anterior mediastinum. Further imaging with CT angiogram showed a stalk-like connection to the pericardium. A biopsy of the mass showed spindle cells positive for BCL-2, CD34, and STAT 6, indicative of a solitary fibrous tumor. A surveillance approach was adopted for the patient. Conclusion: Primary pericardial tumors are exceedingly rare, with a prevalence rate of 0.001%-0.007%. Diagnosing a SFT requires a positive CD34 and BCL-2 marker. The current recommendation is resection of localized disease which has been documented to be curative in cases of benign disease however our patient was put on surveillance.
MeSH term(s)	Male ; Humans ; Aged, 80 and over ; Solitary Fibrous Tumors/diagnostic imaging ; Solitary Fibrous Tumors/surgery ; Mediastinum ; Tomography, X-Ray Computed ; Biopsy
Language	English
Publishing date	2022-08-30
Publishing country	United States
Document type	Review ; Case Reports
ISSN	2573-8348
ISSN (online)	2573-8348
DOI	10.1002/cnr2.1698
Database	MEDical Literature Analysis and Retrieval System OnLINE

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