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Article ; Online: Self-assembled 3D-microstructured dual carbon black filled polymer nanocomposite-coated fabric for tunable electromagnetic interference shielding

Sarkar, Kajal / Khanra, Sipra / Sharma, Sujit / Ghorai, Sanjoy Kumar / Chattopadhyay, Santanu

The Journal of The Textile Institute. 2023 Feb. 1, v. 114, no. 2 p.207-216

2023

Abstract: Dual carbon black (CB) was used to create self-assembled three-dimensional (3D)-microstructured polymer nanocomposite by a simple solution mixing process. A mechanical stirrer was employed for uniform dispersion and minimizing CB aggregates sizes in the ... ...

Abstract	Dual carbon black (CB) was used to create self-assembled three-dimensional (3D)-microstructured polymer nanocomposite by a simple solution mixing process. A mechanical stirrer was employed for uniform dispersion and minimizing CB aggregates sizes in the viscous blended medium of hydrolyzed polyvinyl alcohol (PVA) and natural rubber latex (NRL). A stable 3D-microstructural architecture was obtained when an extremely high volume fraction (0.54) of dual CB was used. 3D-microstructured polymer nanocomposite was then applied on the cotton fabric and characterized for the final performance of electromagnetic interference (EMI) shielding effectiveness. The morphological and microstructural analysis revealed that dual CB at a particular ratio of 10:90 (smaller:larger) could provide excellent electrical conductivity (>1.5 S/cm) as well as EMI shielding when assessed against a frequency range of 8.2–12.4 GHz. A durable ultra-thin layer (100 µm) of nanocomposite was sufficient to achieve tunable >31 dB shielding effectiveness.
Keywords	cotton fabric ; electrical conductivity ; electromagnetic interference ; hydrolysis ; latex ; polymer nanocomposites ; polyvinyl alcohol ; rubber ; soot ; Polymer nanocomposite ; microstructure ; coated fabric ; electrical properties ; EMI shielding
Language	English
Dates of publication	2023-0201
Size	p. 207-216.
Publishing place	Taylor & Francis
Document type	Article ; Online
ISSN	1754-2340
DOI	10.1080/00405000.2022.2026577
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Croup Associated With SARS-CoV-2: Pediatric Laryngotracheitis During the Omicron Surge.

Sharma, Sujit / Agha, Beesan / Delgado, Carlos / Walson, Karen / Woods, Charles / Gonzalez, Mark D / Jerris, Robert / Sysyn, Gregory / Beiter, James / Kamidani, Satoshi / Rostad, Christina A

Journal of the Pediatric Infectious Diseases Society

2022 Volume 11, Issue 8, Page(s) 371–374

Abstract: In this retrospective analysis, we describe weekly croup and corresponding viral prevalence patterns in a pediatric quaternary care system in metropolitan Atlanta. We characterize a series of 24 patients with croup associated with SARS-CoV-2 infection ... ...

Abstract	In this retrospective analysis, we describe weekly croup and corresponding viral prevalence patterns in a pediatric quaternary care system in metropolitan Atlanta. We characterize a series of 24 patients with croup associated with SARS-CoV-2 infection and show that this clinical presentation increased substantially in frequency during the period of high Omicron vs Delta transmission.
MeSH term(s)	COVID-19 ; Child ; Croup/epidemiology ; Humans ; Retrospective Studies ; SARS-CoV-2
Language	English
Publishing date	2022-05-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2668791-4
ISSN	2048-7207 ; 2048-7193
ISSN (online)	2048-7207
ISSN	2048-7193
DOI	10.1093/jpids/piac032
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Frontostriatothalamic effective connectivity and dopaminergic function in the psychosis continuum.

Brain : a journal of neurology

2022 Volume 146, Issue 1, Page(s) 372–386

Abstract: Dysfunction of fronto-striato-thalamic (FST) circuits is thought to contribute to dopaminergic dysfunction and symptom onset in psychosis, but it remains unclear whether this dysfunction is driven by aberrant bottom-up subcortical signalling or impaired ... ...

Abstract	Dysfunction of fronto-striato-thalamic (FST) circuits is thought to contribute to dopaminergic dysfunction and symptom onset in psychosis, but it remains unclear whether this dysfunction is driven by aberrant bottom-up subcortical signalling or impaired top-down cortical regulation. We used spectral dynamic causal modelling of resting-state functional MRI to characterize the effective connectivity of dorsal and ventral FST circuits in a sample of 46 antipsychotic-naïve first-episode psychosis patients and 23 controls and an independent sample of 36 patients with established schizophrenia and 100 controls. We also investigated the association between FST effective connectivity and striatal 18F-DOPA uptake in an independent healthy cohort of 33 individuals who underwent concurrent functional MRI and PET. Using a posterior probability threshold of 0.95, we found that midbrain and thalamic connectivity were implicated as dysfunctional across both patient groups. Dysconnectivity in first-episode psychosis patients was mainly restricted to the subcortex, with positive symptom severity being associated with midbrain connectivity. Dysconnectivity between the cortex and subcortical systems was only apparent in established schizophrenia patients. In the healthy 18F-DOPA cohort, we found that striatal dopamine synthesis capacity was associated with the effective connectivity of nigrostriatal and striatothalamic pathways, implicating similar circuits to those associated with psychotic symptom severity in patients. Overall, our findings indicate that subcortical dysconnectivity is evident in the early stages of psychosis, that cortical dysfunction may emerge later in the illness, and that nigrostriatal and striatothalamic signalling are closely related to striatal dopamine synthesis capacity, which is a robust marker for psychosis.
MeSH term(s)	Humans ; Dopamine/metabolism ; Psychotic Disorders/diagnostic imaging ; Schizophrenia/diagnostic imaging ; Schizophrenia/metabolism ; Dihydroxyphenylalanine ; Magnetic Resonance Imaging ; Neural Pathways/physiology
Chemical Substances	Dopamine (VTD58H1Z2X) ; fluorodopa F 18 (2C598205QX) ; Dihydroxyphenylalanine (63-84-3)
Language	English
Publishing date	2022-01-31
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80072-7
ISSN	1460-2156 ; 0006-8950
ISSN (online)	1460-2156
ISSN	0006-8950
DOI	10.1093/brain/awac018
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Article ; Online: Monitoring metabolic side effects of atypical antipsychotics in people with an intellectual disability.

Teeluckdharry, Sadira / Sharma, Sujit / O'Rourke, Elizabeth / Tharian, Priyanka / Gondalekar, Anjali / Nainar, Feroz / Roy, Meera

Journal of intellectual disabilities : JOID

2013 Volume 17, Issue 3, Page(s) 223–235

Abstract: This audit was undertaken prospectively to examine the compliance of a group of psychiatrists against guidelines they developed for monitoring the onset of metabolic syndrome, a potential side effect of antipsychotic medication, especially second ... ...

Abstract	This audit was undertaken prospectively to examine the compliance of a group of psychiatrists against guidelines they developed for monitoring the onset of metabolic syndrome, a potential side effect of antipsychotic medication, especially second generation or atypical ones. Phase 1 of the audit was to set standards by a questionnaire survey of participating psychiatrists against Consensus Guidelines on monitoring (American Diabetic Association, 2004), which they favoured. The results led to modifying these guidelines to develop minimum acceptable standards against which their practice was audited in Phase 2. Although in Phase 1, 77% of the psychiatrists felt that they did some baseline recording, Phase 2 finding did not corroborate this--only 53.8% of the notes recorded the assessment of risk factors in personal history; 37.5% risk factors in family history; 31.7% baseline weight and 26.4% baseline blood sugar/lipid levels. In Phase 1, 85% of the psychiatrists thought that they carried out some of the recommended monitoring; our audit found the records of weight monitoring in 69.7% of the notes and blood sugar and lipids monitoring in 44.2%. People with intellectual disability have a shorter life expectancy and increased risk of early death when compared with the general population. Obesity is already a health issue for people with intellectual disability. We discuss the challenges faced by psychiatrists in implementing their own minimum acceptable standards and suggest measures to reduce the metabolic risk associated with antipsychotic medication through increasing awareness--use of information leaflets in accessible format, health promotion and use of side effect checklists and improving access--by working collaboratively with general practitioners utilising the forum of annual health checks.
MeSH term(s)	Adult ; Antipsychotic Agents/adverse effects ; Drug Monitoring/standards ; Guidelines as Topic/standards ; Humans ; Intellectual Disability/drug therapy ; Medical Audit/methods ; Metabolic Syndrome/blood ; Metabolic Syndrome/chemically induced ; Psychiatry/standards
Chemical Substances	Antipsychotic Agents
Language	English
Publishing date	2013-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2071898-6
ISSN	1744-6309 ; 1469-0047 ; 1744-6295
ISSN (online)	1744-6309
ISSN	1469-0047 ; 1744-6295
DOI	10.1177/1744629513495261
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Article ; Online: Acute neck infections in children: who is likely to undergo surgical drainage?

Sauer, Michael W / Sharma, Sujit / Hirsh, Daniel A / Simon, Harold K / Agha, Beesan S / Sturm, Jesse J

The American journal of emergency medicine

2013 Volume 31, Issue 6, Page(s) 906–909

Abstract: Background: Superficial neck infections including lymphadenitis and abscesses are commonly encountered in pediatric emergency departments (PEDs). It is often unclear which patients are likely to develop an abscess that necessitates surgical drainage. In ...

Abstract	Background: Superficial neck infections including lymphadenitis and abscesses are commonly encountered in pediatric emergency departments (PEDs). It is often unclear which patients are likely to develop an abscess that necessitates surgical drainage. In evaluating these patients, computed tomography (CT) and ultrasound are often used to identify/confirm abscess formation. The criteria for determining the need for imaging studies are not well defined. Design/methods: All visits to the study PED were examined in 2009 to 2010. Visits with the diagnosis of cervical lymphadenitis or abscess were identified. Records were retrospectively reviewed to determine the duration of symptoms, fever, previous antibiotic therapy, prior PED visit, size of neck swelling, fluctuance on physical examination, white blood cell count, and results of CT and/or ultrasound obtained in the PED. Data were analyzed to determine which of these characteristics were more likely to be associated with an abscess that was operatively drained. Results: A total of 768 patients were evaluated for neck infections. One hundred twelve (14%) of these pediatric patients underwent abscess drainage in the operating room. Two hundred eighty-nine patients underwent a neck CT and/or ultrasound, of which 119 were positive for abscess. Factors associated with surgical drainage included fluctuance (odds ratio [OR], 18.92; 95% confidence interval [CI], 3.66-31.37), previous emergency department visit (OR, 2.79; 95% CI, 1.34-5.84), and age less than 4 years (OR, 3.01; 95% CI, 1.15-9.87). A recursive partitioning model stratified patients' risk for going to the operating room. Patients without fluctuance and with no prior emergency department visit, along with no prior antibiotic use, have less than 4% chance of having an abscess that necessitates surgical drainage. Conclusions: Pediatric patients who are more likely to have a neck infection that necessitates surgical drainage can be stratified based on clinical characteristics. This knowledge may allow physicians to better predict the resource needs including hospital admission and emergent imaging for neck infection.
MeSH term(s)	Abscess/diagnostic imaging ; Abscess/surgery ; Age Factors ; Child ; Child, Preschool ; Drainage/statistics & numerical data ; Emergency Service, Hospital/statistics & numerical data ; Female ; Humans ; Infant ; Male ; Neck/diagnostic imaging ; Neck/microbiology ; Neck/surgery ; Retrospective Studies ; Tomography, X-Ray Computed
Language	English
Publishing date	2013-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	605890-5
ISSN	1532-8171 ; 0735-6757
ISSN (online)	1532-8171
ISSN	0735-6757
DOI	10.1016/j.ajem.2013.02.043
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Article ; Online: Etomidate versus pentobarbital for computed tomography sedations: report from the Pediatric Sedation Research Consortium.

Baxter, Amy Lynn / Mallory, Michael D / Spandorfer, Philip R / Sharma, Sujit / Freilich, Steven H / Cravero, Joseph

Pediatric emergency care

2007 Volume 23, Issue 10, Page(s) 690–695

Abstract: Objective: To compare efficacy, sedation duration, and adverse events after administration of etomidate or pentobarbital for diagnostic computed tomography (CT) scans.: Methods: A cohort of children sedated for CT scans between July 2004 and October ... ...

Abstract	Objective: To compare efficacy, sedation duration, and adverse events after administration of etomidate or pentobarbital for diagnostic computed tomography (CT) scans. Methods: A cohort of children sedated for CT scans between July 2004 and October 2005 was identified from a prospectively generated Pediatric Sedation Research Consortium database. The 24 Pediatric Sedation Research Consortium institutions prospectively record consecutive sedation data and adverse events on a Web-based tool. This study included all patients of American Society for Anesthesiologists (ASA) class I or II, between 6 months and 6 years old, sedated with etomidate or with intravenous pentobarbital with or without midazolam. Outcomes included sedation efficacy, duration (time from drug administration until cessation of monitoring), and complication rate. Results: Of 3397 pediatric sedations for CT scans, 2587 met age and ASA criteria. Etomidate was administered by pediatric emergency physicians as the sole sedative for 446 sedation service cases; pentobarbital with or without midazolam was used in 396 sedations by a variety of providers. Sedation was "not ideal" for 11 pentobarbital sedations and 1 etomidate sedation. Median etomidate dose was 0.33 mg/kg (intraquartile rank, 0.30-0.44 mg/kg); median pentobarbital dose was 4 mg/kg (intraquartile rank, 3.2-4.8 mg/kg). Mean etomidate sedation (34 minutes; 95% confidence interval [CI], 32-36 minutes) was shorter than pentobarbital (144 minutes; 95% CI, 139-150 minutes). Etomidate patients were younger (24 vs. 29 months), whereas pentobarbital patients were more often of ASA class II (52% vs. 34%), both P < 0.001. Adverse events were more common with pentobarbital (4.5% vs. 0.9%; relative risk, 3.38%; 95% CI, 1.28%-9.45%). One etomidate and 2 pentobarbital patients experienced apnea. Conclusions: Etomidate as given by emergency physicians was more effective and efficient than pentobarbital, with rare adverse events.
MeSH term(s)	Age Factors ; Child, Preschool ; Cohort Studies ; Conscious Sedation/instrumentation ; Conscious Sedation/statistics & numerical data ; Etomidate/therapeutic use ; Humans ; Hypnotics and Sedatives/therapeutic use ; Infant ; Outcome and Process Assessment (Health Care) ; Pentobarbital/therapeutic use ; Retrospective Studies ; Tomography, X-Ray Computed/statistics & numerical data ; Treatment Outcome
Chemical Substances	Hypnotics and Sedatives ; Pentobarbital (I4744080IR) ; Etomidate (Z22628B598)
Language	English
Publishing date	2007-10
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632588-9
ISSN	1535-1815 ; 0749-5161
ISSN (online)	1535-1815
ISSN	0749-5161
DOI	10.1097/PEC.0b013e3181558d5c
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Article ; Online: The role of emergent neuroimaging in children with new-onset afebrile seizures.

Sharma, Sujit / Riviello, James J / Harper, Marvin B / Baskin, Marc N

Pediatrics

2002 Volume 111, Issue 1, Page(s) 1–5

Abstract: Objectives: The objectives of this study were 1) to determine the frequency of clinically significant abnormal neuroimaging in children coming to the emergency department (ED) with new-onset afebrile seizures (ASZ), and 2) to identify children at high ... ...

Abstract	Objectives: The objectives of this study were 1) to determine the frequency of clinically significant abnormal neuroimaging in children coming to the emergency department (ED) with new-onset afebrile seizures (ASZ), and 2) to identify children at high or low risk for clinically significant abnormal neuroimaging. Design/methods: Five hundred consecutive cases of new-onset ASZ seen in the ED of a tertiary care children's hospital were reviewed. Neuroimaging reports were categorized as normal, clinically insignificant abnormal, or clinically significant abnormal. Recursive partition analysis was used to identify clinical variables that separated children into high- and low-risk groups for clinically significant abnormal neuroimaging. Results: Ninety-five percent of patients (475/500) with new-onset ASZ had neuroimaging. Clinically significant abnormal neuroimaging was noted in 8% (95% confidence interval [CI]: 6, 11; 38/475) of patients. Recursive partition analysis identified 2 criteria associated with high risk for clinically significant abnormal neuroimaging: 1) the presence of a predisposing condition, and 2) focal seizure if <33 months old. Of the high-risk patients, 26% (95% CI: 17, 35; 32/121) had clinically significant abnormal neuroimaging compared with 2% (95% CI: 0.6, 3.7; 6/354) in the low-risk group. Conclusions: In this large, retrospective review of children with new-onset ASZ, clinically significant abnormal neuroimaging occurred with relatively low frequency. Emergent neuroimaging should be considered, however, for children who meet high-risk criteria. Well-appearing children who meet low-risk criteria can be safely discharged from the ED (if follow-up can be assured) without emergent neuroimaging, because their risk for clinically significant abnormal neuroimaging is appreciably lower.
MeSH term(s)	Adolescent ; Adult ; Brain Diseases/diagnosis ; Brain Diseases/epidemiology ; Child ; Child, Preschool ; Comorbidity ; Craniocerebral Trauma/diagnosis ; Craniocerebral Trauma/epidemiology ; Humans ; Infant ; Infant, Newborn ; Magnetic Resonance Imaging ; Retrospective Studies ; Risk Assessment ; Seizures/diagnosis ; Seizures/epidemiology ; Tomography, X-Ray Computed
Language	English
Publishing date	2002-12-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	207677-9
ISSN	1098-4275 ; 0031-4005
ISSN (online)	1098-4275
ISSN	0031-4005
DOI	10.1542/peds.111.1.1
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Article ; Online: Self-assembled 3D-microstructured dual carbon black filled polymer nanocomposite-coated fabric for tunable electromagnetic interference shielding

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Article ; Online: Croup Associated With SARS-CoV-2: Pediatric Laryngotracheitis During the Omicron Surge.

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Article ; Online: Frontostriatothalamic effective connectivity and dopaminergic function in the psychosis continuum.

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Article ; Online: Monitoring metabolic side effects of atypical antipsychotics in people with an intellectual disability.

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Article ; Online: Acute neck infections in children: who is likely to undergo surgical drainage?

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Article ; Online: Etomidate versus pentobarbital for computed tomography sedations: report from the Pediatric Sedation Research Consortium.

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Article ; Online: The role of emergent neuroimaging in children with new-onset afebrile seizures.

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