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  1. AU="Shea, Puigi Catherine"
  2. AU="Dragana Tričković-Vukić"
  3. AU="Schilpp, Carolin"
  4. AU="Sasaki, Shugo"
  5. AU=Saito Hazime AU=Saito Hazime
  6. AU="King, Kindra M"
  7. AU="Prousi, George S" AU="Prousi, George S"
  8. AU="Bredov, Denis V" AU="Bredov, Denis V"
  9. AU="Saeki, Harumi"
  10. AU="Pillière, Rémy"
  11. AU="Gurung, Janita"
  12. AU=O'Malley Dennis P
  13. AU="Khlestkina, Maria S"
  14. AU="Ebina-Shibuya, Risa"
  15. AU="Vogel, Ida"
  16. AU="Facchiano, Angelo"
  17. AU="Tara Rava Zolnikov"
  18. AU="Akther, Tahmina"
  19. AU=Chung Eugene S
  20. AU=Josephson M E

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  1. Artikel ; Online: Daily ambulatory remote monitoring system for drug escalation in chronic heart failure with reduced ejection fraction: pilot phase of DAVID-HF study.

    Wong, Chun Ka / Un, Ka Chun / Zhou, Mi / Cheng, Yangyang / Lau, Yuk Ming / Shea, Puigi Catherine / Lui, Hin Wai / Zuo, Ming Liang / Yin, Li Xue / Chan, Esther W / Wong, Ian C K / Sin, Simon Wai Ching / Yeung, Pauline Pui Ning / Chen, Hao / Wibowo, Sandi / Wei, Tong Li Nikki / Lee, Sze Ming / Chow, Augustine / Tong, Raymond Cheuk Fung /
    Hai, Jojo / Tam, Frankie Chor Cheung / Siu, Chung Wah

    European heart journal. Digital health

    2022  Band 3, Heft 2, Seite(n) 284–295

    Abstract: Aims: Underutilization of guideline-directed heart failure with reduced ejection fraction (HFrEF) medications contributes to poor outcomes.: Methods and results: A pilot study to evaluate the safety and efficacy of a home-based remote monitoring ... ...

    Abstract Aims: Underutilization of guideline-directed heart failure with reduced ejection fraction (HFrEF) medications contributes to poor outcomes.
    Methods and results: A pilot study to evaluate the safety and efficacy of a home-based remote monitoring system for HFrEF management was performed. The system included wearable armband monitors paired with the smartphone application. An HFrEF medication titration algorithm was used to adjust medication daily. The primary endpoint was HFrEF medication utilization at 120 days. Twenty patients (60.5 ± 8.2 years, men: 85%) with HFrEF were recruited. All received angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB)/angiotensin receptor-neprilysin inhibitor (ARNI) at recruitment; 45% received ≥50% maximal targeted dose (MTD) with % MTD of 44.4 ± 31.7%. At baseline, 90 and 70% received beta-adrenergic blocker and mineralocorticoid receptor antagonist (MRA), 35% received ≥50% MTD beta-adrenergic blocker with % MTD of 34.1 ± 29.6%, and 25% received ≥50% MTD MRA with % MTD of 25.0 ± 19.9%. At 120 days, 70% received ≥50% MTD ACEI/ARB/ARNI (
    Conclusion: Heart failure with reduced ejection fraction medication escalation with remote monitoring appeared feasible.
    Sprache Englisch
    Erscheinungsdatum 2022-05-07
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2634-3916
    ISSN (online) 2634-3916
    DOI 10.1093/ehjdh/ztac024
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Ivabradine in Severe Aortic Stenosis with Poor Left Ventricular Ejection Fraction.

    Huang, Duo / Chan, Pak-Hei / Lam, Chi-Cheung / Shea, Puigi Catherine / Yiu, Kai-Hang / Tse, Hung-Fat / Siu, Chung-Wah

    The Journal of heart valve disease

    2015  Band 24, Heft 4, Seite(n) 433–435

    Abstract: Patients with severe aortic stenosis (AS) and left ventricular systolic dysfunction pose a significant challenge to the managing physician. Conventional pharmacological therapy for systolic heart failure has not been proven beneficial in this setting. ... ...

    Abstract Patients with severe aortic stenosis (AS) and left ventricular systolic dysfunction pose a significant challenge to the managing physician. Conventional pharmacological therapy for systolic heart failure has not been proven beneficial in this setting. Ivabradine, a selective current inhibitor, decreases the spontaneous firing rate of sinoatrial nodal cells, thereby reducing the heart rate, and has been shown to reduce a composite end-point of heart failure hospitalization and mortality in patients with impaired left ventricular function. Herein are reported details of the hemodynamic effects and clinical outcome of ivabradine treatment in an 86-year-old man with severe AS and severe left ventricular systolic function.
    Mesh-Begriff(e) Aged, 80 and over ; Aortic Valve Stenosis/diagnosis ; Aortic Valve Stenosis/physiopathology ; Aortic Valve Stenosis/therapy ; Benzazepines/therapeutic use ; Cardiac Catheterization/methods ; Cardiovascular Agents/therapeutic use ; Electrocardiography ; Heart Failure, Systolic/diagnosis ; Heart Failure, Systolic/drug therapy ; Heart Failure, Systolic/physiopathology ; Heart Rate/drug effects ; Heart Valve Prosthesis Implantation/methods ; Humans ; Male ; Recovery of Function ; Severity of Illness Index ; Stroke Volume ; Treatment Outcome ; Ventricular Dysfunction, Left/diagnosis ; Ventricular Dysfunction, Left/physiopathology ; Ventricular Function, Left
    Chemische Substanzen Benzazepines ; Cardiovascular Agents ; ivabradine (3H48L0LPZQ)
    Sprache Englisch
    Erscheinungsdatum 2015-07
    Erscheinungsland England
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 1205265-6
    ISSN 2053-2644 ; 0966-8519
    ISSN (online) 2053-2644
    ISSN 0966-8519
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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