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  1. Article: Current evidence of PD-1 and PD-L1 immune checkpoint inhibitors for esophageal cancer: an updated meta-analysis and synthesis of ongoing clinical trials.

    Zafar, Saram / Shehzadi, Rabbia / Dawood, Hina / Maqbool, Moeez / Sarfraz, Azza / Sarfraz, Zouina

    Therapeutic advances in medical oncology

    2024  Volume 16, Page(s) 17588359231221339

    Abstract: Background: Esophageal cancer (EC) is the sixth leading cause of cancer mortality worldwide, with a poor prognosis and a 5-year survival rate of 5% in advanced cases.: Objectives: To evaluate the efficacy of programmed death-1 (PD-1) and programmed ... ...

    Abstract Background: Esophageal cancer (EC) is the sixth leading cause of cancer mortality worldwide, with a poor prognosis and a 5-year survival rate of 5% in advanced cases.
    Objectives: To evaluate the efficacy of programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) inhibitors in EC patients by analyzing phase III clinical trials.
    Design: A meta-analysis following the PRISMA Statement 2020 guidelines.
    Methods: PubMed/MEDLINE, Web of Science, and Embase were searched through 6 December 2022, and the analysis was conducted using Review Manager 5.4.3 (Cochrane).
    Results: Out of 387 studies, 13 phase III clinical trials with 6519 participants were pooled. Overall survival (OS) favored PD-1/PD-L1 inhibitors with a Cohen's
    Conclusion: This meta-analysis provides strong evidence that PD-1/PD-L1 inhibitors combined with chemotherapy improve OS and objective response rate among patients with advanced EC but do not affect progression-free survival.
    Trial registration: Open Science Framework: osf.io/y27rx.
    Language English
    Publishing date 2024-01-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2503443-1
    ISSN 1758-8359 ; 1758-8340
    ISSN (online) 1758-8359
    ISSN 1758-8340
    DOI 10.1177/17588359231221339
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Correlation of arsenic level in drinking water and hair of male respondents of district Sheikhupura.

    Abbas, Moneeza / Cheema, Kausar Jamal / Shehzadi, Rabia

    JPMA. The Journal of the Pakistan Medical Association

    2019  Volume 69, Issue 4, Page(s) 499–503

    Abstract: Objective: To find out the correlation between arsenic concentration in drinking water and biological samples of young male respondents.: Methods: The cross-sectional study was conducted at Lahore College for Women University, Lahore, Pakistan, from ... ...

    Abstract Objective: To find out the correlation between arsenic concentration in drinking water and biological samples of young male respondents.
    Methods: The cross-sectional study was conducted at Lahore College for Women University, Lahore, Pakistan, from March 2013 to February 2015, and comprised biological samples i.e. hair of young males aged 15-25 years from Sheikhupura district of the Punjab province. The study questionnaire was designed to assess the general health status of the subjects as well. Drinking water samples were collected from the houses of those who volunteered to fill up the questionnaire and gave hair samples for the study. Acid digestion method was used to pre-treat the water and hair samples for the analysis of arsenic content. Atomic absorption spectrophotometer method was used to measure arsenic concentration. SPSS 13 was used for data analysis.
    Results: There were 100 subjects and as many water samples. Overall, 46(46%) respondents had a range of health problems, including acne, skin lesions, allergies and respiratory problems. The average arsenic concentration was higher in water samples of tehsil Sheikhupura (67.11±3.8μg/L) and Sharaqpur (61.65± 3.3μg/L) than Muridke (41.7±1.5 μg/L), Ferozwala (40.79± 1.3 μg/L) and Safdarabad (29.7± 0.5 μg/L) (p< 0.05). Positive correlation was established between arsenic in drinking water and hair samples with respect to area and age (p<0.05).
    Conclusions: The presence of arsenic in drinking water was found to be likely affecting general metabolism and its accumulation in biological tissues..
    MeSH term(s) Adolescent ; Arsenic/analysis ; Cross-Sectional Studies ; Drinking Water/chemistry ; Hair/chemistry ; Humans ; Male ; Pakistan ; Spectrophotometry, Atomic ; Young Adult
    Chemical Substances Drinking Water ; Arsenic (N712M78A8G)
    Language English
    Publishing date 2019-04-18
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 845: Show issues Location:
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  3. Book ; Thesis: Measurement of beauty production in deep inelastic scattering at HERA using decays into electrons

    Shehzadi, Ramoona

    (BONN-IR ; 2011,1)

    2011  

    Author's details von Ramoona Shehzadi
    Series title BONN-IR ; 2011,1
    Language English
    Size VI, 197 S., Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Bonn, 2011
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Article ; Online: Charged Particles Transverse Momentum and Pseudorapidity Distribution in Hadronic Collisions at LHC Energies.

    Ajaz, Muhammad / Haj Ismail, Abd Al Karim / Ullah Mian, Mateen / Khan, Rashid / Shehzadi, Ramoona / Adil Khan, Muhammad / AbdelKader, Atef / Waqas, Muhammad / Dawi, Elmuez A / Tabassam, Uzma

    Entropy (Basel, Switzerland)

    2023  Volume 25, Issue 3

    Abstract: We present an analysis of the pseudorapidity η and transverse momentum pT distributions of charged hadrons in pp collisions for the kinematic range of 0

    Abstract We present an analysis of the pseudorapidity η and transverse momentum pT distributions of charged hadrons in pp collisions for the kinematic range of 0<pT<4 GeV/c and |η|<2.4 at 0.9, 2.36, and 7 TeV. Charged particles are produced in pp collision using several Monte Carlo event generators (Pythia Simple, Vincia, Dire showers, Sibyll2.3d, QGSJETII-04, EPOS-LHC) and compared with CMS data at LHC. It is observed that the Simple parton showers can explain the CMS data very well for pT>1 GeV/c at 0.9 and 2.36 TeV within the experimental errors, while Dire overshoots and Vicia undershoots the data by 50% each. At 7 TeV, the Dire module presents a good prediction, whereas the Simple and Vincia modules underestimate the data within 30% and 50%. Comparing the Simple module of the Pythia model and the predictions of the CRMC models with the experimental data shows that at 0.9 TeV, EPOS-LHC has better results than the others. At 2.36 GeV, the cosmic rays Monte Carlo (CRMC) models have better prediction than the Simple module of Pythia at low pT, while QGSJETII-04 predicts well at high pT. QGSJETII-04 and EPOS-LHC have closer results than the Pythia-Simple and Sibyll2.3d at 7 TeV. In the case of the pseudorapidity distributions, only the Pythia-Simple reproduced the experimental measurements at all energies. The Dire module overestimates, while Vincia underestimates the data in decreasing order of discrepancy (20%, 12%, 5%) with energy. All CRMC models underestimate the data over the entire η range at all energies by 20%. The angular ordering of partons and the parton fragmentation could be possible reasons for this deviation. Furthermore, we used the two-component standard distribution to fit the pT spectra to the experimental data and extracted the effective temperature (Teff) and the multiplicity parameter (N0). It is observed that Teff increases with the increase in the center of mass energy. The fit yielded 0.20368±0.01, 0.22348±0.011, and 0.24128±0.012 GeV for 0.9, 2.36, and 7 TeV, respectively. This shows that the system at higher energies freezes out earlier than lower ones because they quickly attain the equilibrium state.
    Language English
    Publishing date 2023-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e25030452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Thesis: Measurement of beauty production in deep inelastic scattering at HERA using decays into electrons

    Shehzadi, Ramoona

    2010  

    Author's details vorgelegt von Ramoona Shehzadi
    Language English
    Size VI, 197 S., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Bonn, 2010
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Book ; Online: A Precisely Xtreme-Multi Channel Hybrid Approach For Roman Urdu Sentiment Analysis

    Memood, Faiza / Ghani, Muhammad Usman / Ibrahim, Muhammad Ali / Shehzadi, Rehab / Asim, Muhammad Nabeel

    2020  

    Abstract: In order to accelerate the performance of various Natural Language Processing tasks for Roman Urdu, this paper for the very first time provides 3 neural word embeddings prepared using most widely used approaches namely Word2vec, FastText, and Glove. The ... ...

    Abstract In order to accelerate the performance of various Natural Language Processing tasks for Roman Urdu, this paper for the very first time provides 3 neural word embeddings prepared using most widely used approaches namely Word2vec, FastText, and Glove. The integrity of generated neural word embeddings is evaluated using intrinsic and extrinsic evaluation approaches. Considering the lack of publicly available benchmark datasets, it provides a first-ever Roman Urdu dataset which consists of 3241 sentiments annotated against positive, negative and neutral classes. To provide benchmark baseline performance over the presented dataset, we adapt diverse machine learning (Support Vector Machine Logistic Regression, Naive Bayes), deep learning (convolutional neural network, recurrent neural network), and hybrid approaches. Effectiveness of generated neural word embeddings is evaluated by comparing the performance of machine and deep learning based methodologies using 7, and 5 distinct feature representation approaches respectively. Finally, it proposes a novel precisely extreme multi-channel hybrid methodology which outperforms state-of-the-art adapted machine and deep learning approaches by the figure of 9%, and 4% in terms of F1-score. Roman Urdu Sentiment Analysis, Pretrain word embeddings for Roman Urdu, Word2Vec, Glove, Fast-Text
    Keywords Computer Science - Computation and Language
    Subject code 006
    Publishing date 2020-03-11
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Study of Kinetic Freeze-Out Parameters as a Function of Rapidity in pp Collisions at CERN SPS Energies.

    Waqas, Muhammad / Chen, Huai-Min / Peng, Guang-Xiong / Haj Ismail, Abd Al Karim / Ajaz, Muhammad / Wazir, Zafar / Shehzadi, Ramoona / Jamal, Sabiha / AbdelKader, Atef

    Entropy (Basel, Switzerland)

    2021  Volume 23, Issue 10

    Abstract: We used the blast wave model with the Boltzmann-Gibbs statistics and analyzed the experimental data measured by the NA61/SHINE Collaboration in inelastic (INEL) proton-proton collisions at different rapidity slices at different center-of-mass energies. ... ...

    Abstract We used the blast wave model with the Boltzmann-Gibbs statistics and analyzed the experimental data measured by the NA61/SHINE Collaboration in inelastic (INEL) proton-proton collisions at different rapidity slices at different center-of-mass energies. The particles used in this study were π+, π-, K+, K-, and p¯. We extracted the kinetic freeze-out temperature, transverse flow velocity, and kinetic freeze-out volume from the transverse momentum spectra of the particles. We observed that the kinetic freeze-out temperature is rapidity and energy dependent, while the transverse flow velocity does not depend on them. Furthermore, we observed that the kinetic freeze-out volume is energy dependent, but it remains constant with changing the rapidity. We also observed that all three parameters are mass dependent. In addition, with the increase of mass, the kinetic freeze-out temperature increases, and the transverse flow velocity, as well as kinetic freeze-out volume decrease.
    Language English
    Publishing date 2021-10-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e23101363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Multisectoral development for improved health outcomes: evaluation of community-based initiatives in the Islamic Republic of Iran.

    Sheikh, M R / Afzal, M M / Ali, S Z / Hussain, A / Shehzadi, R

    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit

    2012  Volume 16, Issue 12, Page(s) 1231–1236

    Abstract: Community-based initiatives (CBI) are based on integrated multisectoral socioeconomic development with community participation and intersectoral support to improve the health and quality of life of the people. During 2005-06 the World Health Organization ...

    Abstract Community-based initiatives (CBI) are based on integrated multisectoral socioeconomic development with community participation and intersectoral support to improve the health and quality of life of the people. During 2005-06 the World Health Organization supported an evaluation of CBI in the Islamic Republic of Iran by collecting information from intervention villages on social capital and other indicators, with validation of the findings. The data showed some positive changes in the intervention areas compared with control villages. The evaluation suggests that the CBI approach is a useful tool for improving health and social indicators and providing mechanisms for community-based participation and intersectoral collaboration for health and development at the local level.
    Language English
    Publishing date 2012-12-04
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 1291071-5
    ISSN 1687-1634 ; 1020-3397
    ISSN (online) 1687-1634
    ISSN 1020-3397
    DOI 10.26719/2010.16.12.1231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4388: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book ; Online: Multisectoral development for improved health outcomes

    Ali, S Z / Shehzadi, R / Hussain, A / Afzal, M M / Sheikh, M R

    evaluation of community-based initiatives in the Islamic Republic of Iran

    2010  

    Abstract: Journal Article ... Community-based initiatives (CBI) are based on integrated multisectoral socioeconomic development with community participation and intersectoral support to improve the health and quality of life of the people. During 2005-06 the World ... ...

    Abstract Journal Article

    Community-based initiatives (CBI) are based on integrated multisectoral socioeconomic development with community participation and intersectoral support to improve the health and quality of life of the people. During 2005-06 the World Health Organization supported an evaluation of CBI in the Islamic Republic of Iran by collecting information from intervention villages on social capital and other indicators, with validation of the findings. The data showed some positive changes in the intervention areas compared with control villages. The evaluation suggests that the CBI approach is a useful tool for improving health and social indicators and providing mechanisms for community-based participation and intersectoral collaboration for health and development at the local level.
    Language English
    Publishing date 2010-12-01
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Book ; Online: Multisectoral development for improved health outcomes

    Sheikh, M.R. / Afzal, M.M. / Ali, S.Z. / Hussain, A. / Shehzadi, R.

    evaluation of community-based initiatives in the Islamic Republic of Iran

    2010  

    Abstract: 1231-1236 ... Community-based initiatives [CBI] are based on integrated multisectoral socioeconomic development with community participation and intersectoral support to improve the health and quality of life of the people. During 2005-06 the World Health ... ...

    Abstract 1231-1236

    Community-based initiatives [CBI] are based on integrated multisectoral socioeconomic development with community participation and intersectoral support to improve the health and quality of life of the people. During 2005-06 the World Health Organization supported an evaluation of CBI in the Islamic Republic of Iran by collecting information from intervention villages on social capital and other indicators, with validation of the findings. The data showed some positive changes in the intervention areas compared with control villages. The evaluation suggests that the CBI approach is a useful tool for improving health and social indicators and providing mechanisms for community-based participation and intersectoral collaboration for health and development at the local level
    Keywords Delivery of Health Care ; Evaluation Studies as Topic ; Quality of Health Care ; Outcome and Process Assessment ; Health Care
    Language English
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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