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Article ; Online: Snoring-related artifact: scalp EEG correlate of historical "limbic spindles".

Sheikh, Zubeda

Epileptic disorders : international epilepsy journal with videotape

2021 Volume 23, Issue 1, Page(s) 201–202

MeSH term(s)	Artifacts ; Electroencephalography/methods ; Electroencephalography/standards ; Humans ; Snoring
Language	English
Publishing date	2021-02-19
Publishing country	France
Document type	Journal Article
ZDB-ID	2086797-9
ISSN	1950-6945 ; 1294-9361
ISSN (online)	1950-6945
ISSN	1294-9361
DOI	10.1684/epd.2021.1241
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Article: A practical approach to in-hospital management of new-onset refractory status epilepticus/febrile infection related epilepsy syndrome.

Sheikh, Zubeda / Hirsch, Lawrence J

Frontiers in neurology

2023 Volume 14, Page(s) 1150496

Abstract: New-onset refractory status epilepticus (NORSE) is "a clinical presentation, not a specific diagnosis, in a patient without active epilepsy or other preexisting relevant neurological disorder, with new onset of refractory status epilepticus without a ... ...

Abstract	New-onset refractory status epilepticus (NORSE) is "a clinical presentation, not a specific diagnosis, in a patient without active epilepsy or other preexisting relevant neurological disorder, with new onset of refractory status epilepticus without a clear acute or active structural, toxic, or metabolic cause." Febrile infection related epilepsy syndrome (FIRES) is "a subcategory of NORSE that requires a prior febrile infection, with fever starting between 2 weeks and 24 h before the onset of refractory status epilepticus, with or without fever at the onset of status epilepticus." These apply to all ages. Extensive testing of blood and CSF for infectious, rheumatologic, and metabolic conditions, neuroimaging, EEG, autoimmune/paraneoplastic antibody evaluations, malignancy screen, genetic testing, and CSF metagenomics may reveal the etiology in some patients, while a significant proportion of patients' disease remains unexplained, known as NORSE of unknown etiology or cryptogenic NORSE. Seizures are refractory and usually super-refractory (i.e., persist despite 24 h of anesthesia), requiring a prolonged intensive care unit stay, often (but not always) with fair to poor outcomes. Management of seizures in the initial 24-48 h should be like any case of refractory status epilepticus. However, based on the published consensus recommendations, the first-line immunotherapy should begin within 72 h using steroids, intravenous immunoglobulins, or plasmapheresis. If there is no improvement, the ketogenic diet and second-line immunotherapy should start within seven days. Rituximab is recommended as the second-line treatment if there is a strong suggestion or proof of an antibody-mediated disease, while anakinra or tocilizumab are recommended for cryptogenic cases. Intensive motor and cognitive rehab are usually necessary after a prolonged hospital stay. Many patients will have pharmacoresistant epilepsy at discharge, and some may need continued immunologic treatments and an epilepsy surgery evaluation. Extensive research is in progress now via multinational consortia relating to the specific type(s) of inflammation involved, whether age and prior febrile illness affect this, and whether measuring and following serum and/or CSF cytokines can help determine the best treatment.
Language	English
Publishing date	2023-05-12
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2023.1150496
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Article ; Online: Scalp myiasis associated with soft tissue sarcoma lesion: a case report and review of relevant literature.

Azarmi, Sahar / Akbarzadeh, Kamran / Ekrami, Ali / Sheikh, Zahra / Dehghan, Omid

BMC infectious diseases

2024 Volume 24, Issue 1, Page(s) 51

Abstract: Background: Sarcophagidae is one of the main fly families that is attracted to open wounds, ulcers, lesions, and other injuries for depositing their larvae. The presence of larvae of flies in human tissues makes myiasis. Myiasis on the scalp could be ... ...

Abstract	Background: Sarcophagidae is one of the main fly families that is attracted to open wounds, ulcers, lesions, and other injuries for depositing their larvae. The presence of larvae of flies in human tissues makes myiasis. Myiasis on the scalp could be more frightening in comparison with myiasis on the other parts of the body. It is a rare myiasis case that shows the ability of myiasis agents to attack various parts of the body. On the other hand, reporting of myiasis cases by Sarcophagidae larvae is not common due to difficulties in their identification. This study aimed to emphasize the importance of Sarcohagidae larvae in producing myiasis by describing the first case of soft tissue sarcoma infestation and provides a review of human myiasis by larvae of the Sarcophagidae family during 2010-2023 and also a review of wound myiasis cases associated with malignancy during 2000-2023. Case presentation: A case of sarcoma cancer myiasis is reported on the scalp of a 43-year-old man who referred to one of Tehran's hospitals for surgical treatment of cancer. Before surgery, insect larvae were observed in the area of sarcoma. The larvae were isolated, examined morphologically, and identified as Sarcophaga spp. Conclusions: Myiasis has been considered as a neglected disease. Publishing of myiasis cases could be useful to alert health policy-makers about its danger and appearance in the community. It is not usual but can be expected even on the scalp of the human head. Exact daily supervision and dressing of the wound could be recommended to prevent cutaneous myiasis.
MeSH term(s)	Male ; Animals ; Humans ; Adult ; Scalp ; Iran ; Sarcoma ; Myiasis/complications ; Myiasis/diagnosis ; Larva
Language	English
Publishing date	2024-01-05
Publishing country	England
Document type	Case Reports ; Review ; Journal Article
ZDB-ID	2041550-3
ISSN	1471-2334 ; 1471-2334
ISSN (online)	1471-2334
ISSN	1471-2334
DOI	10.1186/s12879-023-08957-8
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Article ; Online: A retrospective review of the 5-year nutritional and clinical outcomes in pediatric patients undergoing intestinal rehabilitation

Sheikh, Zaid / Adigun, Ayoola / Duro, Debora

European Society for Clinical Nutrition and Metabolism Clinical Nutrition ESPEN. 2023 June, v. 55 p.277-284

2023

Abstract: The mainstay of modern medical therapy for intestinal failure (IF) is parenteral nutrition (PN). The Intestinal Rehabilitation Program (IRP) goal is enhancing nutritional outcomes for patients receiving total parenteral nutrition (TPN), optimizing/ ... ...

Abstract	The mainstay of modern medical therapy for intestinal failure (IF) is parenteral nutrition (PN). The Intestinal Rehabilitation Program (IRP) goal is enhancing nutritional outcomes for patients receiving total parenteral nutrition (TPN), optimizing/transitioning patients from TPN to enteral nutrition (EN), achieving enteral autonomy, monitoring growth and development. The objective of this study is to describe nutritional and clinical outcomes for children undergoing intestinal rehabilitation during 5 years of the program. Retrospective chart review for children from birth to <18 years old with IF who were on TPN from July 2015 to Dec 2020 or to the endpoint of the study when they either weaned from TPN during the 5 year period or continued TPN by Dec 2020 and participated at our IRP. The mean age of the cohort was 2.4 years (±4.22), 53% male. The 3 most common diagnosis were necrotizing enterocolitis (28%), gastroschisis (14%) and intestinal atresia (14%). Nutritional data including days/hours per week on TPN, glucose infusion rate, amino acids, total EN calories, % of total nutrition received from TPN and EN per day all showed statistically significant differences. Our program showed 0% intestinal failure associated liver disease (IFALD), 0% mortality, 100% survival, 41% patients were weaned from TPN (13/32) with mean of 39 months (±32). Early referral to a center that can offer IRP, such as ours can lead to tremendous positive clinical outcomes and help patients with intestinal failure avoid transplant as shown in our study.
Keywords	abnormal development ; clinical nutrition ; enteral feeding ; enterocolitis ; glucose ; growth and development ; intestines ; liver diseases ; males ; mortality ; total parenteral nutrition ; Intestinal failure ; Parenteral nutrition in children ; Short bowel syndrome ; Intestinal rehabilitation in children ; Home parenteral nutrition ; Pediatrics
Language	English
Dates of publication	2023-06
Size	p. 277-284.
Publishing place	Elsevier Ltd
Document type	Article ; Online
ISSN	2405-4577
DOI	10.1016/j.clnesp.2023.03.018
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Article: The Eye as a Diagnostic Tool for Alzheimer's Disease.

Hussain, Ahsan / Sheikh, Zahra / Subramanian, Manju

Life (Basel, Switzerland)

2023 Volume 13, Issue 3

Abstract: Alzheimer's disease (AD) is a progressive neurodegenerative disorder impacting cognition, function, and behavior in the elderly population. While there are currently no disease-modifying agents capable of curing AD, early diagnosis and management in the ... ...

Abstract	Alzheimer's disease (AD) is a progressive neurodegenerative disorder impacting cognition, function, and behavior in the elderly population. While there are currently no disease-modifying agents capable of curing AD, early diagnosis and management in the preclinical stage can significantly improve patient morbidity and life expectancy. Currently, the diagnosis of Alzheimer's disease is a clinical one, often supplemented by invasive and expensive biomarker testing. Over the last decade, significant advancements have been made in our understanding of AD and the role of ocular tissue as a potential biomarker. Ocular biomarkers hold the potential to provide noninvasive and easily accessible diagnostic and monitoring capabilities. This review summarizes current research for detecting biomarkers of Alzheimer's disease in ocular tissue.
Language	English
Publishing date	2023-03-08
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life13030726
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Article: Municipal wastewater treatment with corrugated PVC carrier anaerobic baffled reactor.

Ullah, Nadeem / Sheikh, Zeshan / Badshah, Malik

Water science and technology : a journal of the International Association on Water Pollution Research

2023 Volume 87, Issue 3, Page(s) 660–671

Abstract: The anaerobic baffled reactor (ABR) is a promising solution for decentralized wastewater treatment due to its low operation cost as compared to the activated sludge process, but it requires comparatively higher hydraulic retention time (HRT). This ... ...

Abstract	The anaerobic baffled reactor (ABR) is a promising solution for decentralized wastewater treatment due to its low operation cost as compared to the activated sludge process, but it requires comparatively higher hydraulic retention time (HRT). This ultimately increases land requirement, capital and construction cost of treatment plant. This study investigates performance of ABR using polyvinyl chloride (PVC) corrugated pipe as carrier media to improve biomass retention capacity and treatment performance of reactor with the aim to reduce HRT. Comparative performance of two ABRs with and without carrier media was analyzed under mesophilic conditions (35 ± 1 °C) for organics and total suspended solids (TSS) removal at HRTs of 24, 18, 12, 8, 6 and 4 h. Results showed that at HRTs of 24-08 h, the organics removal performance of the carrier anaerobic baffled reactor (CABR) was better than ABR and was in the range of 77-81% for CABR as compared to 64-70% for ABR. However, on further decrease in HRT to 6 h, CABR sustained the treatment with organics removal of 80%, while ABR performance reduced to 58%, creating a performance difference of 38%. Average total suspended solids (TSS) removal was in the range of 76-83% at all HRTs for both reactors. Therefore, this study identified CABR with PVC carrier media as an effective low-HRT reactor for organics and SS removal with less land area requirement.
MeSH term(s)	Waste Disposal, Fluid/methods ; Anaerobiosis ; Bioreactors ; Sewage ; Water Purification
Chemical Substances	Sewage
Language	English
Publishing date	2023-02-15
Publishing country	England
Document type	Journal Article
ZDB-ID	764273-8
ISSN	1996-9732 ; 0273-1223
ISSN (online)	1996-9732
ISSN	0273-1223
DOI	10.2166/wst.2022.414
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Article ; Online: A retrospective review of the 5-year nutritional and clinical outcomes in pediatric patients undergoing intestinal rehabilitation.

Sheikh, Zaid / Adigun, Ayoola / Duro, Debora

Clinical nutrition ESPEN

2023 Volume 55, Page(s) 277–284

Abstract: Background: The mainstay of modern medical therapy for intestinal failure (IF) is parenteral nutrition (PN). The Intestinal Rehabilitation Program (IRP) goal is enhancing nutritional outcomes for patients receiving total parenteral nutrition (TPN), ... ...

Abstract	Background: The mainstay of modern medical therapy for intestinal failure (IF) is parenteral nutrition (PN). The Intestinal Rehabilitation Program (IRP) goal is enhancing nutritional outcomes for patients receiving total parenteral nutrition (TPN), optimizing/transitioning patients from TPN to enteral nutrition (EN), achieving enteral autonomy, monitoring growth and development. The objective of this study is to describe nutritional and clinical outcomes for children undergoing intestinal rehabilitation during 5 years of the program. Methods: Retrospective chart review for children from birth to <18 years old with IF who were on TPN from July 2015 to Dec 2020 or to the endpoint of the study when they either weaned from TPN during the 5 year period or continued TPN by Dec 2020 and participated at our IRP. Results: The mean age of the cohort was 2.4 years (±4.22), 53% male. The 3 most common diagnosis were necrotizing enterocolitis (28%), gastroschisis (14%) and intestinal atresia (14%). Nutritional data including days/hours per week on TPN, glucose infusion rate, amino acids, total EN calories, % of total nutrition received from TPN and EN per day all showed statistically significant differences. Our program showed 0% intestinal failure associated liver disease (IFALD), 0% mortality, 100% survival, 41% patients were weaned from TPN (13/32) with mean of 39 months (±32). Conclusion: Early referral to a center that can offer IRP, such as ours can lead to tremendous positive clinical outcomes and help patients with intestinal failure avoid transplant as shown in our study.
MeSH term(s)	Child ; Humans ; Infant, Newborn ; Male ; Child, Preschool ; Adolescent ; Female ; Retrospective Studies ; Intestinal Failure ; Short Bowel Syndrome ; Treatment Outcome ; Intestines ; Intestinal Diseases/therapy
Language	English
Publishing date	2023-03-29
Publishing country	England
Document type	Journal Article
ISSN	2405-4577
ISSN (online)	2405-4577
DOI	10.1016/j.clnesp.2023.03.018
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Article ; Online: Pearls & Oy-sters: Driving Safety in Photosensitive Genetic Generalized Epilepsy.

Nasser, Mohamed / Sheikh, Zubeda

Neurology

2021 Volume 97, Issue 10, Page(s) e1057–e1059

Language	English
Publishing date	2021-05-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	207147-2
ISSN	1526-632X ; 0028-3878
ISSN (online)	1526-632X
ISSN	0028-3878
DOI	10.1212/WNL.0000000000012157
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Article ; Online: Introducing day case thyroid lobectomy at a tertiary head and neck centre.

Sheikh, Z / Lingamanaicker, V / Irune, E / Fish, B / Jani, P

Annals of the Royal College of Surgeons of England

2021 Volume 103, Issue 7, Page(s) 499–503

Abstract: Background: Thyroid lobectomy is considered to be a safe day case procedure by the British Association of Day Surgery. However, currently only 5.5% of thyroid surgeries in the UK are undertaken as day cases. We determine if and how thyroid lobectomy ... ...

Abstract	Background: Thyroid lobectomy is considered to be a safe day case procedure by the British Association of Day Surgery. However, currently only 5.5% of thyroid surgeries in the UK are undertaken as day cases. We determine if and how thyroid lobectomy with same-day discharge could safely be introduced in our centre. Methods: We analysed all thyroid lobectomy surgeries performed between April 2015 and May 2019. Exclusion criteria included completion surgery, revision surgery, additional procedures and disseminated disease. Outcomes were benchmarked against surgeon-reported complications from the British Association of Endocrine and Thyroid Surgery's 5 Results: In total, 259 thyroid lobectomy surgeries were undertaken and of these 173 met the inclusion criteria. There was no mortality, return to theatre for evacuation of postoperative haematoma or readmission. There was one postoperative haematoma which was drained at the bedside. Some 47 of the 173 (27.2%) patients met day case criteria currently in use at our centre. Conclusions: Day case surgery provides a cost-effective solution to rising bed pressures and a coherent protocol can optimise patient safety and experience.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Ambulatory Surgical Procedures/adverse effects ; Child ; Cost-Benefit Analysis ; Feasibility Studies ; Female ; Hematoma/epidemiology ; Hematoma/etiology ; Humans ; Male ; Middle Aged ; Patient Readmission/economics ; Patient Readmission/statistics & numerical data ; Patient Safety ; Postoperative Complications/economics ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Reoperation/economics ; Reoperation/statistics & numerical data ; Retrospective Studies ; Tertiary Care Centers/economics ; Tertiary Care Centers/statistics & numerical data ; Thyroid Diseases/economics ; Thyroid Diseases/surgery ; Thyroidectomy/adverse effects ; Thyroidectomy/economics ; Thyroidectomy/methods ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2021-06-03
Publishing country	England
Document type	Journal Article
ZDB-ID	80044-2
ISSN	1478-7083 ; 0035-8843
ISSN (online)	1478-7083
ISSN	0035-8843
DOI	10.1308/rcsann.2020.7063
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Article ; Online: Vellus hair removal with 1064-nm neodymium: Yttrium-aluminum-garnet laser: A prospective study.

Azizpour, Arghavan / Nourmohammadpour, Pedram / Nassimi, Maryam / Nemati, Roya / Sheikh, Zahra / Aryanian, Zeinab / Hatami, Parvaneh

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

2024 Volume 30, Issue 3, Page(s) e13661

MeSH term(s)	Humans ; Hair Removal ; Prospective Studies ; Neodymium ; Lasers, Solid-State/therapeutic use ; Aluminum ; Yttrium
Chemical Substances	yttrium-aluminum-garnet ; Neodymium (2I87U3734A) ; Aluminum (CPD4NFA903) ; Yttrium (58784XQC3Y)
Language	English
Publishing date	2024-03-10
Publishing country	England
Document type	Letter
ZDB-ID	1229160-2
ISSN	1600-0846 ; 0909-752X ; 1397-1344
ISSN (online)	1600-0846
ISSN	0909-752X ; 1397-1344
DOI	10.1111/srt.13661
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