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Article: Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons.

Wang, Guoqiang / Guasp, Ryan / Salam, Sangeena / Chuang, Edward / Morera, Andrés / Smart, Anna J / Jimenez, David / Shekhar, Sahana / Melentijevic, Ilija / Nguyen, Ken C / Hall, David H / Grant, Barth D / Driscoll, Monica

bioRxiv : the preprint server for biology

2023  

Abstract: Large vesicle extrusion from neurons may contribute to spreading pathogenic protein aggregates and promoting inflammatory responses, two mechanisms leading to neurodegenerative disease. Factors that regulate extrusion of large vesicles, such as exophers ... ...

Abstract Large vesicle extrusion from neurons may contribute to spreading pathogenic protein aggregates and promoting inflammatory responses, two mechanisms leading to neurodegenerative disease. Factors that regulate extrusion of large vesicles, such as exophers produced by proteostressed
Language English
Publishing date 2023-11-16
Publishing country United States
Document type Preprint
DOI 10.1101/2023.11.13.565361
Database MEDical Literature Analysis and Retrieval System OnLINE

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