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  1. Article: Micromonospora profundi

    Lu, Di / Shen, Hong-Ling / Wang, Lei / Wan, Chuan-Xing

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1236906

    Abstract: Plant growth and agricultural productivity was greatly limited by soil salinity and alkalization. The application of salt-tolerant rhizobacteria could effectively improve plant tolerance to saline-alkali stress. ...

    Abstract Plant growth and agricultural productivity was greatly limited by soil salinity and alkalization. The application of salt-tolerant rhizobacteria could effectively improve plant tolerance to saline-alkali stress.
    Language English
    Publishing date 2023-09-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1236906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Three novel

    Ding, La-Mei / Ding, Pei-Zhi / Liu, Wen-Long / Shen, Hong-Ling / Xia, Zhan-Feng / Wan, Chuan-Xing / Zhang, Li-Li

    International journal of systematic and evolutionary microbiology

    2023  Volume 73, Issue 2

    Abstract: Three novel actinomycete strains, designated TRM66264- ... ...

    Abstract Three novel actinomycete strains, designated TRM66264-DLM
    MeSH term(s) Fatty Acids/chemistry ; Actinoplanes ; Phosphatidylethanolamines ; Water ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Arabinose ; Sequence Analysis, DNA ; DNA, Bacterial/genetics ; Base Composition ; Bacterial Typing Techniques ; Glucose ; Vitamin K 2 ; Phospholipids/analysis
    Chemical Substances Fatty Acids ; Phosphatidylethanolamines ; polyaspartate (26063-13-8) ; Water (059QF0KO0R) ; RNA, Ribosomal, 16S ; Arabinose (B40ROO395Z) ; DNA, Bacterial ; Glucose (IY9XDZ35W2) ; Vitamin K 2 (11032-49-8) ; Phospholipids
    Language English
    Publishing date 2023-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2002336-4
    ISSN 1466-5034 ; 1466-5026
    ISSN (online) 1466-5034
    ISSN 1466-5026
    DOI 10.1099/ijsem.0.005705
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 409: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: [Effect of extracellular signal-regulated kinase pathway on nitric oxide release by human umbilical vein endothelial cell induced by placental growth factor-1].

    Shen, Hong-ling / Chen, Han-ping

    Zhonghua fu chan ke za zhi

    2008  Volume 43, Issue 6, Page(s) 410–413

    Abstract: Objective: To investigate the effect of extracellular signal-regulated kinase (ERK) pathway on nitric oxide (NO) release by human umbilical vein endothelial cell (HUVEC) induced by placental growth factor-1 (PLGF-1).: Methods: During January to April ...

    Abstract Objective: To investigate the effect of extracellular signal-regulated kinase (ERK) pathway on nitric oxide (NO) release by human umbilical vein endothelial cell (HUVEC) induced by placental growth factor-1 (PLGF-1).
    Methods: During January to April 2006, 50 samples of umbilical vein blood were collected from newborns delivered by cesarean section due to intrauterine distress and abnormal fetal position. HUVEC were primarily cultured by trypsin digestion. Then the following procedures were performed: (1) Cells were identified using the morphology and VIII factor immunohistochemistry methods if the culture was satisfactory. (2) Cells were collected, and fms-like tyrosin kinase (Flt-1) protein and its mRNA expression were detected with immunoprints and RT-PCR methods. (3) The protein was extracted after cells were treated with PLGF-1 (cells were collected before the treatment and 2.5, 5, 10, 20 min after the treatment). The protein levels of ERK were determined by immunoprints. (4) The cells were cultured with serum-free culture medium containing PLGF-1 only (culture media were collected 20, 40, 160, 360, 480, 720 and 1440 min after the treatment). The quantity of NO was detected with nitrate reductase method. (5) The cells were cultured with serum-free culture medium containing PD98059, the inhibitor of mitogen-activated protein kinase (MAPK)/MEK for 60 min. Then the cells were cultured continuously with the serum-free culture medium containing PLGF-1 for 60 min. The culture media were collected. The quantity of NO was detected by nitrate reductase method. The samples were divided into treatment group and control group. Control group was exactly the same in treatment time, culture condition, and time to collect the cells as the treatment group, except that it was not treated with PLGF-1 or PD 98059.
    Results: (1) By morphology and VIII factor immunohistochemistry the cultured cells were identified to be HUVEC. (2) Flt-1 mRNA and protein were expressed in HUVEC. (3) Expression of ERK protein started to increase at 2.5 min after treatment of HUVEC with PLGF-1, reaching the peak at 5 min, and decreased at 10 min. (4) In comparison with the control group, NO started to increase at 20 min after treatment of HUVEC with PLGF-1 (6.96 +/- 0.34) micromol/L, significantly increased at 40 min (9.45 +/- 0.59) micromol/L, and arrived at the peak at 480 min (15.82 +/- 0.69) micromol/L Comparison between the two groups showed a significant difference (P<0.05). (5) Release of NO from the cells treated with PD98059 for 1 hour and PLGF was significantly inhibited, compared with the cells treated with PLGF-1 only.
    Conclusion: ERK pathways play an important role in NO release by HUVEC induced by PLGF.
    MeSH term(s) Blotting, Western ; Cells, Cultured ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Female ; Flavonoids/pharmacology ; Humans ; Nitric Oxide/metabolism ; Placenta Growth Factor ; Pregnancy Proteins/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction ; Time Factors ; Umbilical Veins/cytology ; Vascular Endothelial Growth Factor Receptor-1/genetics ; Vascular Endothelial Growth Factor Receptor-1/metabolism
    Chemical Substances Flavonoids ; PGF protein, human ; Pregnancy Proteins ; RNA, Messenger ; Placenta Growth Factor (144589-93-5) ; Nitric Oxide (31C4KY9ESH) ; Vascular Endothelial Growth Factor Receptor-1 (EC 2.7.10.1) ; Extracellular Signal-Regulated MAP Kinases (EC 2.7.11.24) ; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one (SJE1IO5E3I)
    Language Chinese
    Publishing date 2008-11-19
    Publishing country China
    Document type Journal Article
    ZDB-ID 604570-4
    ISSN 0529-567X
    ISSN 0529-567X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1619: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 324: Show issues

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  4. Article ; Online: Plasma sFlt-1-to-PlGF ratio is correlated with inflammatory but not with oxidative stress in Chinese preeclamptic women.

    Ouyang, Yan-Qiong / Li, Si-Jian / Zhang, Qing / Xiang, Wen-Pei / Shen, Hong-Ling / Chen, Han-Ping / Chen, Hong / Chen, Hui-Zhen

    Archives of gynecology and obstetrics

    2009  Volume 280, Issue 1, Page(s) 91–97

    Abstract: Purpose: Considerable interest has been focused on angiogenic factors and angiogenic imbalance in the field of pre-eclampsia (PE), owing to its gaining role in the development of PE. This study was addressed to investigate the associations of sFlt-1-to- ... ...

    Abstract Purpose: Considerable interest has been focused on angiogenic factors and angiogenic imbalance in the field of pre-eclampsia (PE), owing to its gaining role in the development of PE. This study was addressed to investigate the associations of sFlt-1-to-PlGF plasma ratios with oxidative stress assessed by the level of 8-isoprostane, and inflammation measured by the level of high-sensitive C-reactive protein (hs-CRP), and adipocytokines.
    Methods: A total of 83 patients with PE including 47 mild PE (MPE) and 36 severe PE (SPE) and 50 age-matched normotensive subjects in the third trimester of pregnancy were examined. Measurements included body mass index (BMI), systolic and diastolic blood pressure (BP) levels, plasma concentrations of hs-CRP, 8-isoprostane, adiponectin, and leptin.
    Results: Subjects with PE had higher levels of sFlt-1/PlGF (P < 0.01), hs-CRP (P < 0.01), 8-isoprostane and leptin (both P < 0.01) and lower adiponectin (P < 0.01) than did normotensive control subjects. Significant positive correlations were found between plasma sFlt-1/PlGF and hs-CRP (r = 0.437, P < 0.01) or leptin (r = 0.656, P < 0.01). A weak inverse correlation emerged between sFlt-1/PlGF and adiponectin (r = -0.306, P < 0.01). When a multiple regression analysis was performed, with sFlt-1/PlGF as a dependent variable and all the other parameters as independent variables, sFlt-1/PlGF maintain a significant relationship with leptin (beta = 0.219, P < 0.05) and with hs-CRP (beta = 0.295, P < 0.01) as well as with systolic BP(beta = 0.446, P < 0.05).
    Conclusions: In Chinese preeclamptic women, plasma sFlt-1-to-PlGF ratio is correlated with inflammatory and adipocytokines but not with oxidative stress.
    MeSH term(s) Adipokines/blood ; Adult ; Biomarkers/blood ; Blood Pressure ; C-Reactive Protein/metabolism ; Case-Control Studies ; China ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Inflammation/complications ; Oxidative Stress/physiology ; Placenta Growth Factor ; Pre-Eclampsia/blood ; Pre-Eclampsia/etiology ; Pre-Eclampsia/metabolism ; Pregnancy ; Pregnancy Proteins/blood ; Pregnancy Trimester, Third ; Reference Values ; Regression Analysis ; Statistics, Nonparametric ; Vascular Endothelial Growth Factor Receptor-1/blood
    Chemical Substances Adipokines ; Biomarkers ; PGF protein, human ; Pregnancy Proteins ; Placenta Growth Factor (144589-93-5) ; C-Reactive Protein (9007-41-4) ; FLT1 protein, human (EC 2.7.10.1) ; Vascular Endothelial Growth Factor Receptor-1 (EC 2.7.10.1)
    Language English
    Publishing date 2009-07
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-008-0874-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Um I Zs.55: Show issues Location:
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