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Article ; Online: Risk factors and predictive model for pulmonary complications in patients transferred to ICU after hepatectomy.

Wang, Bin / Liang, HanSheng / Zhao, HuiYing / Shen, JiaWei / An, YouZhong / Feng, Yi

2023 Volume 23, Issue 1, Page(s) 150

Abstract: Objective: Postoperative pulmonary complications (PPCs) seriously harm the recovery and prognosis of patients undergoing surgery. However, its related risk factors in critical patients after hepatectomy have been rarely reported. This study aimed at ... ...

Abstract	Objective: Postoperative pulmonary complications (PPCs) seriously harm the recovery and prognosis of patients undergoing surgery. However, its related risk factors in critical patients after hepatectomy have been rarely reported. This study aimed at analyzing the factors related to PPCs in critical adult patients after hepatectomy and create a nomogram for prediction of the PPCs. Methods: 503 patients' data were collected form the Peking University People's Hospital. Multivariate logistic regression analysis was used to identify independent risk factors to derive the nomogram. Nomogram's discriminatory ability was assessed using the area under the receiver operating characteristic curve (AUC), and calibration was assessed using the Hosmer-Lemeshow goodness-of-fit test and calibration curve. Results: The independent risk factor for PPCs are advanced age (odds ratio [OR] = 1.026; P = 0.008), higher body mass index (OR = 1.139; P < 0.001), lower preoperative serum albumin level (OR = 0.961; P = 0.037), and intensive care unit first day infusion volume (OR = 1.152; P = 0.040). And based on this, we created a nomogram to predict the occurrence of PPCs. Upon assessing the nomogram's predictive ability, the AUC for the model was 0.713( 95% CI: 0.668-0.758, P<0.001). The Hosmer-Lemeshow test (P = 0.590) and calibration curve showed good calibration for the prediction of PPCs. Conclusions: The prevalence and mortality of postoperative pulmonary complications in critical adult patients after hepatectomy are high. Advanced age, higher body mass index, lower preoperative serum albumin and intensive care unit first day infusion volume were found to be significantly associated with PPCs. And we created a nomogram model which can be used to predict the occurrence of PPCs.
MeSH term(s)	Adult ; Humans ; Hepatectomy/adverse effects ; Risk Factors ; Prognosis ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Intensive Care Units ; Serum Albumin ; Retrospective Studies
Chemical Substances	Serum Albumin
Language	English
Publishing date	2023-06-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2050442-1
ISSN	1471-2482 ; 1471-2482
ISSN (online)	1471-2482
ISSN	1471-2482
DOI	10.1186/s12893-023-02019-1
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Article ; Online: Revision of Eupines King of New Zealand (Coleoptera: Staphylinidae: Pselaphinae: Goniaceritae).

Shen, Jia-Wei / Leschen, Richard A B

Zootaxa

2020 Volume 4777, Issue 1, Page(s) zootaxa.4777.1.1

Abstract: The species-rich genus Eupines King of New Zealand is revised to include 48 species, with 22 known species redescribed. Twenty-two new species are described: Eupines (Byraxis) brevis sp. n., E. (B.) caesta sp. n., E. (B.) carinata sp. n., E. (B.) coalita ...

Abstract	The species-rich genus Eupines King of New Zealand is revised to include 48 species, with 22 known species redescribed. Twenty-two new species are described: Eupines (Byraxis) brevis sp. n., E. (B.) caesta sp. n., E. (B.) carinata sp. n., E. (B.) coalita sp. n., E. (B.) complector sp. n., E. (B.) dugdalei sp. n., E. (B.) gigas sp. n., E. (B.) graceae sp. n., E. (B.) huizhenae sp. n., E. (B.) hoarei sp. n., E. (B.) insolita sp. n., E. (B.) mayae sp. n., E. (B.) minuta sp. n., E. (B.) obtusa sp. n., E. (B.) ovalis sp. n., E. (B.) pannicula sp. n., E. (B.) petila sp. n., E. (B.) protibialis sp. n., E. (B.) whirinaki sp. n., E. (B.) waikaremoana sp. n., Eupines (Eupines) undecim sp. n. and Eupines novem sp. n. The following 11 synonymies are proposed: E. (B.) dispar (Sharp) (= E. (B.) munroi Broun syn. n.), E. (B.) hectori Broun (= E. (B.) diversides Newton syn. n.), E. (B.) impar (Sharp) (= E. (B.) sanguineua Broun syn. n., E. (B.) foveatissima Broun syn. n.), E. (B.) monstrosa (Reitter) (= E. (B.) rudicornis Broun syn. n., E. (B.) costata Broun syn. n.), E. (B.) mundula (Schaufuss) (= E. (B.) forficulida Broun syn. n.), E. (B.) paganus (Broun) (= E. (B.) allocera Broun syn. n., E. (B.) sylvicola Broun syn. n., E. (B.) rhyssarthra Broun syn. n.) and Eupinolus altulus (Broun) (= E. (E.) nasuta Broun syn. n.). New combinations are proposed for four species previously described in Eupines: Eupinolus calcaratus (Broun) new comb., Eupinolus nasutus (Broun) new comb., Gastrobothrus ignotus (Broun) new comb. and Gastrobothrus platynotus (Broun) new comb. A key and distribution maps for all New Zealand members of Eupines are provided.
MeSH term(s)	Animals ; Coleoptera ; New Zealand
Language	English
Publishing date	2020-05-12
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.4777.1.1
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Article ; Online: Erratum: JIA-WEI SHEN amp; RICHARD A. B. LESCHEN (2020) Revision of Eupines King of New Zealand (Coleoptera: Staphylinidae: Pselaphinae: Goniaceritae) Zootaxa, 4777: 001-084.

Shen, Jia-Wei / Leschen, Richard A B

Zootaxa

2020 Volume 4809, Issue 3, Page(s) zootaxa.4809.3.13

Language	English
Publishing date	2020-07-08
Publishing country	New Zealand
Document type	Journal Article ; Published Erratum
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.4809.3.13
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Article ; Online: Theoretical study of protein adsorption on graphene/h-BN heterostructures.

Lan, Jun / Peng, Yiran / Liang, Lijun / Duan, Xing / Kong, Zhe / Zhang, Li / Shen, Jia-Wei

Physical chemistry chemical physics : PCCP

2023 Volume 25, Issue 45, Page(s) 31206–31221

Abstract: The biological characteristics of planar heterojunction nanomaterials and their interactions with biomolecules are crucial for the potential application of these materials in the biomedical field. This study employed molecular dynamics (MD) simulations ... ...

Abstract	The biological characteristics of planar heterojunction nanomaterials and their interactions with biomolecules are crucial for the potential application of these materials in the biomedical field. This study employed molecular dynamics (MD) simulations to investigate the interactions between proteins with distinct secondary structures (a single α-helix representing the minimal oligomeric domain protein, a single β-sheet representing the WW structural domain of the Yap65 protein, and a mixed α/β structure representing the BBA protein) and a planar two-dimensional heterojunction (a GRA/h-BN heterojunction consisting of a graphene nanoplate (GRA) and a hexagonal boron nitride nanoplate (h-BN)). The results indicate that all three kinds of protein can be quickly and stably adsorbed on the GRA/h-BN heterojunction due to the strong van der Waals interaction, regardless of their respective types, structures and initial orientations. Moreover, the proteins exhibit a pronounced binding preference for the hBN region of the GRA/h-BN heterojunction. Upon adsorption, the α-helix structure of the minimal oligomeric domain protein experiences partial or complete denaturation. Conversely, while the secondary structure of the single β-sheet and mixed α/β structure (BBA protein) undergoes slight changes (focus on the coil and turn regions), the main α-helix and β-sheet structures remain intact. The initial orientation significantly impacts the degree of protein adsorption and its position on the GRA/h-BN heterojunction. However, regardless of the initial orientation, proteins can ultimately be adsorbed onto the GRA/h-BN heterojunction. Furthermore, the initial orientation has a minor influence on the structural changes of proteins. Significantly, the combination of different secondary structures helps mitigate the denaturation of a single α-helix structure to some extent. Overall, the adsorption of proteins on GRA/h-BN is primarily driven by van der Waals and hydrophobic interactions. Proteins with β-sheet or mixed structures exhibit stronger biocompatibility on the GRA/h-BN heterojunction. Our research elucidated the biological characteristics of GRA/h-BN heterojunction nanomaterials and their interactions with proteins possessing diverse secondary structures. It offers a theoretical foundation for considering heterojunction nanomaterials as promising candidates for biomedical applications.
MeSH term(s)	Graphite/chemistry ; Adsorption ; Molecular Dynamics Simulation ; Boron Compounds/chemistry
Chemical Substances	Graphite (7782-42-5) ; boron nitride (2U4T60A6YD) ; Boron Compounds
Language	English
Publishing date	2023-11-22
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d3cp03303a
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Article ; Online: Adaptability of melanocytes post ultraviolet stimulation in patients with melasma.

Wang, Yen-Jen / Chang, Chang-Cheng / Wu, Yu-Hung / Huang, Ling / Shen, Jia-Wei / Lu, Meng-En / Chiang, Hsiu-Mei / Lin, Bor-Shyh

Lasers in surgery and medicine

2023 Volume 55, Issue 7, Page(s) 680–689

Abstract: Background: Dynamic in vivo changes in melanin in melasma lesions after exposure to ultraviolet (UV) irradiation have not been described.: Objectives: To determine whether melasma lesions and nearby perilesions demonstrated different adaptive ... ...

Abstract	Background: Dynamic in vivo changes in melanin in melasma lesions after exposure to ultraviolet (UV) irradiation have not been described. Objectives: To determine whether melasma lesions and nearby perilesions demonstrated different adaptive responses to UV irradiation and whether the tanning responses were different among different locations on face. Methods: We collected sequential images from real-time cellular resolution full-field optical coherence tomography (CRFF-OCT) at melasma lesions and perilesions among 20 Asian patients. Quantitative and layer distribution analyses for melanin were performed using a computer-aided detection (CADe) system that utilizes spatial compounding-based denoising convolutional neural networks. Results: The detected melanin (D) is melanin with a diameter >0.5 µm, among which confetti melanin (C) has a diameter of >3.3 µm and corresponds to a melanosome-rich package. The calculated C/D ratio is proportional to active melanin transportation. Before UV exposure, melasma lesions had more detected melanin (p = 0.0271), confetti melanin (p = 0.0163), and increased C/D ratio (p = 0.0152) in the basal layer compared to those of perilesions. After exposure to UV irradiation, perilesions have both increased confetti melanin (p = 0.0452) and the C/D ratio (p = 0.0369) in basal layer, and this effect was most prominent in right cheek (p = 0.030). There were however no significant differences in the detected, confetti, or granular melanin areas before and after exposure to UV irradiation in melasma lesions in all the skin layers. Conclusions: Hyperactive melanocytes with a higher baseline C/D ratio were noted in the melasma lesions. They were "fixed" on the plateau and were not responsive to UV irradiation regardless of the location on face. Perilesions retained adaptability with a dynamic response to UV irradiation, in which more confetti melanin was shed, mainly in the basal layer. Therefore, aggravating effect of UV on melasma was mainly due to UV-responsive perilesions rather than lesions.
MeSH term(s)	Humans ; Melanins/analysis ; Melanocytes/chemistry ; Melanocytes/pathology ; Melanosis ; Skin/pathology ; Epidermis/pathology ; Ultraviolet Rays
Chemical Substances	Melanins
Language	English
Publishing date	2023-06-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	604493-1
ISSN	1096-9101 ; 0196-8092
ISSN (online)	1096-9101
ISSN	0196-8092
DOI	10.1002/lsm.23699
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Zs.A 1603: Show issues

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Article ; Online: Significantly enhanced enzymatic hydrolysis of waste rice hull through a novel surfactant-based deep eutectic solvent pretreatment.

Tang, Zheng-Yu / Li, Lei / Tang, Wei / Shen, Jia-Wei / Yang, Qi-Zhen / Ma, Cuiluan / He, Yu-Cai

Bioresource technology

2023 Volume 381, Page(s) 129106

Abstract: The potential of green solvents, specifically deep eutectic solvents (DESs), has piqued the interest of researchers in the field of lignocellulose pretreatment. To enhance the enzymatic digestion efficiency of waste rice hull (RCH), an effective ... ...

Abstract	The potential of green solvents, specifically deep eutectic solvents (DESs), has piqued the interest of researchers in the field of lignocellulose pretreatment. To enhance the enzymatic digestion efficiency of waste rice hull (RCH), an effective pretreatment approach was developed using the DES [AA][CATB], which was made with acetic acid (AA) and cetyltrimethylammonium bromide (CTAB). The results showed that [AA][CATB] improved enzymatic saccharification by 3.7 times compared to raw RCH and efficiently eliminated lignin and removed xylan. The improvement in enzymatic hydrolysis efficiency was then interpreted by a series of characterizations that showed a great morphological changed RCH with an obvious accessibility increase and a lignin surface area and hydrophobicity reduction. This work demonstrates that functional, and easily recoverable DESs have potential for improving the efficiency of lignocellulose pretreatment in biorefineries, providing a promising approach for developing green solvents and achieving more sustainable and efficient biorefinery processes.
MeSH term(s)	Lignin ; Oryza ; Deep Eutectic Solvents ; Surface-Active Agents ; Hydrolysis ; Solvents ; Biomass ; Acetic Acid
Chemical Substances	Lignin (9005-53-2) ; Deep Eutectic Solvents ; Surface-Active Agents ; Solvents ; Acetic Acid (Q40Q9N063P)
Language	English
Publishing date	2023-04-29
Publishing country	England
Document type	Journal Article
ZDB-ID	1065195-0
ISSN	1873-2976 ; 0960-8524
ISSN (online)	1873-2976
ISSN	0960-8524
DOI	10.1016/j.biortech.2023.129106
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Article ; Online: Catalogue and type designations for New Zealand Goniaceritae (Coleoptera: Staphylinidae: Pselaphinae).

Shen, Jia-Wei / Leschen, Richard A B

Zootaxa

2019 Volume 4614, Issue 2, Page(s) zootaxa.4614.2.2

Abstract: A catalogue for the eight Goniaceritae genera that occur in New Zealand is presented, treating a total of 62 species. Seventeen holotypes are confirmed, 38 lectotypes and 99 paralectotypes are designated herein for all valid species but Eupines acceptus ... ...

Abstract	A catalogue for the eight Goniaceritae genera that occur in New Zealand is presented, treating a total of 62 species. Seventeen holotypes are confirmed, 38 lectotypes and 99 paralectotypes are designated herein for all valid species but Eupines acceptus Broun, for which type material was not located. One synonymy is proposed: Anabaxis electrica (King, 1863) (= Rybaxis brevis Oke, 1928). Four species of Eupines known only by females are valid species, but without subgeneric assignment. Images of primary type specimens and their original labels are provided.
MeSH term(s)	Animal Distribution ; Animals ; Coleoptera ; Female ; New Zealand
Language	English
Publishing date	2019-06-10
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.4614.2.2
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Article ; Online: Reviving Intervertebral Discs: Treating Degeneration Using Advanced Delivery Systems.

Zhang, Hong / Yang, Xiaorong / Huang, Yiheng / Li, Yue / Hu, Quan / Wei, Qiaolin / Xu, Weixing / Ding, Weiguo / Guo, Yong / Shen, Jia-Wei

Molecular pharmaceutics

2024 Volume 21, Issue 2, Page(s) 373–392

Abstract: Intervertebral disc degeneration (IVDD) is commonly associated with many spinal problems, such as low back pain, and significantly impacts a patient's quality of life. However, current treatments for IVDD, which include conservative and surgical methods, ...

Abstract	Intervertebral disc degeneration (IVDD) is commonly associated with many spinal problems, such as low back pain, and significantly impacts a patient's quality of life. However, current treatments for IVDD, which include conservative and surgical methods, are limited in their ability to fully address degeneration. To combat IVDD, delivery-system-based therapy has received extensive attention from researchers. These delivery systems can effectively deliver therapeutic agents for IVDD, overcoming the limitations of these agents, reducing leakage and increasing local concentration to inhibit IVDD or promote intervertebral disc (IVD) regeneration. This review first briefly introduces the structure and function of the IVD, and the related pathophysiology of IVDD. Subsequently, the roles of drug-based and bioactive-substance-based delivery systems in IVDD are highlighted. The former includes natural source drugs, nonsteroidal anti-inflammatory drugs, steroid medications, and other small molecular drugs. The latter includes chemokines, growth factors, interleukin, and platelet-rich plasma. Additionally, gene-based and cell-based delivery systems are briefly involved. Finally, the limitations and future development of the combination of therapeutic agents and delivery systems in the treatment of IVDD are discussed, providing insights for future research.
MeSH term(s)	Humans ; Quality of Life ; Intervertebral Disc/metabolism ; Intervertebral Disc Degeneration/drug therapy ; Intervertebral Disc Degeneration/metabolism ; Intercellular Signaling Peptides and Proteins
Chemical Substances	Intercellular Signaling Peptides and Proteins
Language	English
Publishing date	2024-01-22
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2138405-8
ISSN	1543-8392 ; 1543-8384
ISSN (online)	1543-8392
ISSN	1543-8384
DOI	10.1021/acs.molpharmaceut.3c00579
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Zs.A 6250: Show issues

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Article ; Online: CaCO

Yang, Xiaorong / Sun, Yue / Zhang, Hong / Liu, Fengrui / Chen, Qin / Shen, Qiying / Kong, Zhe / Wei, Qiaolin / Shen, Jia-Wei / Guo, Yong

Nanoscale

2024 Volume 16, Issue 14, Page(s) 6876–6899

Abstract: The use of nanocarriers for drug delivery has opened up exciting new possibilities in cancer treatment. Among them, calcium carbonate ( ... ...

Abstract	The use of nanocarriers for drug delivery has opened up exciting new possibilities in cancer treatment. Among them, calcium carbonate (CaCO
MeSH term(s)	Humans ; Drug Delivery Systems/methods ; Photochemotherapy/methods ; Neoplasms/drug therapy ; Combined Modality Therapy ; Nanoparticles/metabolism
Language	English
Publishing date	2024-04-04
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d3nr05986c
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Article ; Online: Photoaging features of melasma: An in vivo layered and quantitative analysis using computer-aided detection of cellular resolution full-field optical coherence tomography.

Chang, Chang-Cheng / Wang, Yen-Jen / Huang, Ling / Chen, I-Ling / Shih, Yu-Chang / Shen, Jia-Wei / Lu, Meng-En / Chiang, Hsiu-Mei / Lin, Bor-Shyh / Wu, Yu-Hung

Journal of the European Academy of Dermatology and Venereology : JEADV

2024

Language	English
Publishing date	2024-03-21
Publishing country	England
Document type	Letter
ZDB-ID	1128828-0
ISSN	1468-3083 ; 0926-9959
ISSN (online)	1468-3083
ISSN	0926-9959
DOI	10.1111/jdv.19971
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Zs.A 3492: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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