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  1. Article: Research on the Mechanism of Corn Price Formation in China Based on the PLS-SEM Model.

    Shen, Xin / Qiu, Cancheng

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 6

    Abstract: After the cancellation of the temporary corn storage system in 2016, the price of corn in China returned to market regulation, resulting in increased price volatility. This study focuses on monthly data from April 2016 to March 2023 in China. The partial ...

    Abstract After the cancellation of the temporary corn storage system in 2016, the price of corn in China returned to market regulation, resulting in increased price volatility. This study focuses on monthly data from April 2016 to March 2023 in China. The partial least squares structural equation modeling (PLS-SEM) is employed to analyze the impact of corn supply and demand factors, substitute prices, monetary supply, international corn prices, and international energy prices on the volatility of corn prices in China. Results indicate that supply and demand factors are the most direct influencers of corn prices, with demand factors having the most significant impact. Monetary supply and substitute prices affect corn prices through the demand side. External factors mainly consist of international energy and corn prices. The impact of international energy on Chinese corn prices is achieved through international corn prices, which directly influence the prices in China. It is recommended to stabilize corn market prices by regulating corn supply and demand, to improve the monitoring and early warning mechanisms for international energy and corn prices, and to implement measures for prudent regulation of monetary supply.
    Language English
    Publishing date 2024-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13060875
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  2. Article: Effect of intercropping with legumes at different rates on the yield and soil physicochemical properties of

    Shen, Xin / Liu, Yalan / Li, Xiangyi / Li, Lei

    Frontiers in plant science

    2024  Volume 15, Page(s) 1351843

    Abstract: Intercropping has the potential to enhance yields and nutrient availability in resource-limited agricultural systems. However, the effects on crop yield nutrients and soil properties can vary considerably depending on the specific plant combinations and ... ...

    Abstract Intercropping has the potential to enhance yields and nutrient availability in resource-limited agricultural systems. However, the effects on crop yield nutrients and soil properties can vary considerably depending on the specific plant combinations and intercropping ratios used. In this study, the advantages and impacts of intercropping
    Language English
    Publishing date 2024-02-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2024.1351843
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  3. Article: Molecular Cloning, Characterization, and Expression of a Receptor for Activated Protein Kinase C1 (RACK1) Gene in

    Cai, Yuefeng / Hu, Jie / Guo, Yepeng / Shen, Xin

    Biology

    2024  Volume 13, Issue 3

    Abstract: The receptor for activated protein kinase C1 (RACK1) belongs to the typical WD repeat family, which is extremely conservative and important in multiple signal transduction pathways related to growth and development that coordinate the intracellular role ... ...

    Abstract The receptor for activated protein kinase C1 (RACK1) belongs to the typical WD repeat family, which is extremely conservative and important in multiple signal transduction pathways related to growth and development that coordinate the intracellular role of various life activities. As a novel protein with versatile functions, it was found in a variety of organisms. In a previous study, we identified the RACK1 sequence of white shrimp from transcriptome data. In this study, we employed specialized bioinformatics software to conduct an in-depth analysis of
    Language English
    Publishing date 2024-03-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology13030174
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  4. Article ; Online: Study on teaching and learning strategies of MOOC-based college English teaching reform from the perspective of game theory

    Shen Xin / Bian Tao

    SHS Web of Conferences, Vol 140, p

    2022  Volume 01015

    Abstract: In China, a new round of college English teaching reform is being conducted in the way of integrating MOOC-based teaching mode. However, the effect is not ideal because lack of optimal strategies. In order to improve the efficiency, this article analyzed ...

    Abstract In China, a new round of college English teaching reform is being conducted in the way of integrating MOOC-based teaching mode. However, the effect is not ideal because lack of optimal strategies. In order to improve the efficiency, this article analyzed the teaching and learning strategies of using MOOC in college English teaching reform from the perspective of game theory. Teachers and students were set as the two sides of “teaching and learning” game. Potential game contradictions have been analyzed. As a result, many appropriate and imaginative strategies have been devised to achieve a “win-win” situation for teachers and students and maximize the efficiency of the teaching reform.
    Keywords mooc ; college english teaching reform ; game theory ; Social Sciences ; H
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Evaluation of screening methods for the students who had close contact with pulmonary tuberculosis patients in Shanghai

    XIAO Xiao / CHEN Jing / SHEN Xin

    Shanghai yufang yixue, Vol 35, Iss 3, Pp 208-

    2023  Volume 212

    Abstract: ObjectiveTo evaluate the current screening methods for the students who were in close contact with tuberculosis patients， that could accurately identify the preventive treatment subjects， and to improve the tuberculosis prevention and control in Shanghai ...

    Abstract ObjectiveTo evaluate the current screening methods for the students who were in close contact with tuberculosis patients， that could accurately identify the preventive treatment subjects， and to improve the tuberculosis prevention and control in Shanghai schools.MethodsThe freshman/sophomore who were in close contact with active tuberculosis patients in the colleges in 2019 were recruited. All the subjects underwent both tuberculin skin test （TST） and QuantiFERON-TB gold in-tube （QFT） test at the enrollment. After signed the informed consent， all of the participants filled in a questionnaire and determined their baseline tuberculosis infection status. They were followed up for 2 years to monitor the conversion of infection status and the incidence of tuberculosis.ResultsFour of 9 （44.4%） positive participants had conversion to negative results， and 5 of 300 （1.7%） negative participants had conversion to positive during the 2-year follow-up， one of which was diagnosed with active tuberculosis. We assessed diagnostic agreement between QFT and TST at different cut-off values. The highest coincidence rate was 94.0% when choosing 15 mm as the cut-off value， with Kappa coefficient of 0.45 （95%CI： 0.32‒0.59）.ConclusionAlthough stricter than the national work requirements， the prevention and control of tuberculosis in Shanghai schools still need to be carried out meticulously. It's necessary to strengthen daily prevention and control measures， and improve the ability of management.
    Keywords pulmonary tuberculosis ; student ; latent tuberculosis infection ; close contacts screening ; Medicine ; R
    Language Chinese
    Publishing date 2023-03-01T00:00:00Z
    Publisher Shanghai Preventive Medicine Association
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Strengthening management of latent tuberculosis infection and accelerating the elimination of the tuberculosis epidemic

    SHEN Xin / XIAO Wenjing / PAN Qichao / WU Guozhu

    Shanghai yufang yixue, Vol 35, Iss 3, Pp 199-

    2023  Volume 202

    Abstract: Screening and preventive treatment for latent tuberculosis infection （LTBI） are important measures to reduce the incidence of active tuberculosis （TB） and its global burden. This paper discusses the current status of LTBI prevalence and preventive ... ...

    Abstract Screening and preventive treatment for latent tuberculosis infection （LTBI） are important measures to reduce the incidence of active tuberculosis （TB） and its global burden. This paper discusses the current status of LTBI prevalence and preventive treatment， risk of incidence in high-risk groups， screening methods， and other interventions， emphasizing the importance of prevention and control as early as possible in a scientific strategy， so as to lay a solid foundation for eliminating TB by 2030.
    Keywords tuberculosis ; latent tuberculosis infection ; preventive treatment ; Medicine ; R
    Language Chinese
    Publishing date 2023-03-01T00:00:00Z
    Publisher Shanghai Preventive Medicine Association
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells.

    Shen, Xin / Jin, Xuli / Fang, Shuang / Chen, Jie

    Cellular & molecular biology letters

    2023  Volume 28, Issue 1, Page(s) 53

    Abstract: Background: Fibulin-like extracellular matrix protein 2 (EFEMP2) has been reported to be related to the progression of various cancers. We have previously reported that EFEMP2 was highly expressed in ovarian cancer and was strongly associated with poor ... ...

    Abstract Background: Fibulin-like extracellular matrix protein 2 (EFEMP2) has been reported to be related to the progression of various cancers. We have previously reported that EFEMP2 was highly expressed in ovarian cancer and was strongly associated with poor prognosis in patients. This study intends to further explore its interacting proteins and possible downstream signaling pathways.
    Method: The expression of EFEMP2 was detected by RT-qPCR, ICC and western blot in 4 kinds of ovarian cancer cells with different migration and invasion ability. Cell models with strong or weak EFEMP2 expression were constructed by lentivirus transfection. The effects of the down-regulation and up-regulation of EFEMP2 on the biological behavior of ovarian cancer cells were studied through in-vitro and in-vivo functional tests. The phosphorylation pathway profiling array and KEGG database analyses identified the downstream EGFR/ERK1/2/c-Jun signaling pathway and the programmed death-1 (PD-L1) pathway enrichment. Additionally, the protein interaction between EFEMP2 and EGFR was detected by immunoprecipitation.
    Result: EFEMP2 was positively correlated with the invasion ability of ovarian cancer cells, its down-regulation inhibited the migrative, invasive and cloning capacity of cancer cells in vitro and suppressed the tumor proliferation and intraperitoneal diffusion in vivo, while its up-regulation did the opposite. Moreover, EFEMP2 could bind to EGFR to induce PD-L1 regulation in ovarian cancer, which was caused by the activation of EGFR/ERK1/2/c-Jun signaling. Similar to EFEMP2, PD-L1 was also highly expressed in aggressive cells and had the ability to promote the invasion and metastasis of ovarian cancer cells both in vitro and in vivo, and PD-L1 upregulation was partly caused by EFEMP2 activation. Afatinib combined with trametinib had an obvious effect of inhibiting the intraperitoneal diffusion of ovarian cancer cells, especially in the group with low expression of EFEMP2, while overexpression of PD-L1 could reverse this phenomenon.
    Conclusion: EFEMP2 could bind to EGFR to activate ERK1/2/c-Jun pathway and regulate PD-L1 expression, furthermore PD-L1 was extremely essential for EFEMP2 to promote ovarian cancer cells invasion and dissemination in vitro and in vivo. Targeted therapy against the source gene EFEMP2 is our future research direction, which may better inhibit the invasion and metastasis of ovarian cancer cells.
    MeSH term(s) Female ; Humans ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Cell Line, Tumor ; ErbB Receptors/metabolism ; Gene Expression Regulation, Neoplastic ; MAP Kinase Signaling System ; Ovarian Neoplasms/genetics ; Signal Transduction ; Extracellular Matrix Proteins/genetics ; Extracellular Matrix Proteins/metabolism
    Chemical Substances B7-H1 Antigen ; EGFR protein, human (EC 2.7.10.1) ; ErbB Receptors (EC 2.7.10.1) ; EFEMP2 protein, human ; Extracellular Matrix Proteins
    Language English
    Publishing date 2023-07-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2108724-6
    ISSN 1689-1392 ; 1689-1392
    ISSN (online) 1689-1392
    ISSN 1689-1392
    DOI 10.1186/s11658-023-00471-8
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  8. Article ; Online: Facile wound dressing replacement: Carbon dots for dissolving alginate hydrogels via competitive complexation.

    Li, Qian / Shen, Xin / Liu, Chenguang / Xing, Dongming

    International journal of biological macromolecules

    2023  Volume 240, Page(s) 124455

    Abstract: Dissolvable hydrogels have shown great potentials in removing the exudes and alleviating pain during wound dressing replacement. Herein, a series of carbon dots (CDs) composing high complexation ability with ... ...

    Abstract Dissolvable hydrogels have shown great potentials in removing the exudes and alleviating pain during wound dressing replacement. Herein, a series of carbon dots (CDs) composing high complexation ability with Cu
    MeSH term(s) Hydrogels ; Alginates ; Lysine ; Bandages ; Wound Healing
    Chemical Substances Hydrogels ; Alginates ; Lysine (K3Z4F929H6)
    Language English
    Publishing date 2023-04-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.124455
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  9. Article ; Online: Remote Sensing of the Subtropical Front in the Southeast Pacific and the Ecology of Chilean Jack Mackerel Trachurus murphyi

    Belkin, Igor M. / Shen, Xin-Tang

    Fishes. 2023 Jan. 02, v. 8, no. 1

    2023  

    Abstract: The Subtropical Front (STF) plays a key role in the ecology of Chilean jack mackerel Trachurus murphyi. Nonetheless, there are few remote sensing studies of the STF in the open Southeast Pacific, and almost all of them have been conducted by satellite ... ...

    Abstract The Subtropical Front (STF) plays a key role in the ecology of Chilean jack mackerel Trachurus murphyi. Nonetheless, there are few remote sensing studies of the STF in the open Southeast Pacific, and almost all of them have been conducted by satellite oceanographers in Russia and Ukraine to support respective large-scale fisheries of jack mackerel in this region. We reviewed these studies that documented long-term seasonal and interannual variability of the STF from sea surface temperature (SST) and sea surface height (SSH) data. We also mapped the STF from satellite sea surface salinity (SSS) data of the SMOS mission (2012–2019). The Subtropical Front consists of two fronts–North and South STF about 500 km apart–that border the Subtropical Frontal Zone (STFZ) in-between. The STF is density-compensated, with spatially divergent manifestations in temperature and salinity. In the temperature field, the STF extends in the WNW to ESE direction in the Southeast Pacific. In the salinity field, the STFZ appears as a broad frontal zone, extending zonally across the entire South Pacific. Three major types of satellite data-SST, SSH, and SSS-can be used to locate the STF. The SSH data is most advantageous with regard to the jack mackerel fisheries, owing to the all-weather capability of satellite altimetry and the radical improvement of the spatial resolution of SSH data in the near future. Despite the dearth of dedicated in situ studies of the South Pacific STFZ, there is a broad consensus regarding the STFZ being the principal spawning and nursing ground of T. murphyi and a migration corridor between Chile and New Zealand. Major data/knowledge gaps are identified, and key next steps are proposed to mitigate the data/knowledge gaps and inform fisheries management.
    Keywords Russia ; Soil Moisture and Ocean Salinity satellite ; Trachurus murphyi ; ecology ; mackerel ; salinity ; satellite altimetry ; surface water temperature ; Chile ; New Zealand ; Ukraine
    Language English
    Dates of publication 2023-0102
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ISSN 2410-3888
    DOI 10.3390/fishes8010029
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Facile wound dressing replacement: Carbon dots for dissolving alginate hydrogels via competitive complexation

    Li, Qian / Shen, Xin / Liu, Chenguang / Xing, Dongming

    International Journal of Biological Macromolecules. 2023 June, v. 240 p.124455-

    2023  

    Abstract: Dissolvable hydrogels have shown great potentials in removing the exudes and alleviating pain during wound dressing replacement. Herein, a series of carbon dots (CDs) composing high complexation ability with Cu²⁺ were prepared for capturing Cu²⁺ from Cu²⁺ ...

    Abstract Dissolvable hydrogels have shown great potentials in removing the exudes and alleviating pain during wound dressing replacement. Herein, a series of carbon dots (CDs) composing high complexation ability with Cu²⁺ were prepared for capturing Cu²⁺ from Cu²⁺-alginate hydrogels. CDs were prepared using biocompatible lysine as the main starting material, while ethylenediamine was chosen as the other starting material for its extremely high complexation ability with Cu²⁺. The complexation ability increased with the increasing amount of ethylenediamine, while the cell viability decreased. When the mass ratio of ethylenediamine to lysine in CDs was above 1/4, six-coordinate copper centers could be formed. CD₁/₄ at the concentration of 90 mg/mL could dissolve Cu²⁺-alginate hydrogels within 16 min, which was about twice faster than lysine. In vivo results showed the replaced hydrogels could ameliorate hypoxic conditions, alleviate local inflammatory reactions and promote the healing speed of burn wounds. Thus, the above results suggested the competitive complexation of CDs with Cu²⁺ could effectively dissolve Cu²⁺-alginate hydrogels, which have much potential in realizing facile wound dressing replacement.
    Keywords alginates ; carbon ; cell viability ; ethylenediamines ; hydrogels ; lysine ; pain ; Carbon dots ; Alginate ; Dissolvable hydrogel
    Language English
    Dates of publication 2023-06
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.124455
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